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Volumn 87, Issue 24, 2013, Pages 13803-13815

Epstein-Barr virus latent membrane protein 2 effects on epithelial acinus development reveal distinct requirements for the PY and YEEA motifs

Author keywords

[No Author keywords available]

Indexed keywords

LATENT MEMBRANE PROTEIN 2; PROTEIN KINASE B; PROTEIN TYROSINE KINASE;

EID: 84888021448     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02203-13     Document Type: Article
Times cited : (9)

References (38)
  • 1
    • 0026594257 scopus 로고
    • Epstein-Barr virus latent gene transcription in nasopharyngeal carcinoma cells:coexpression of EBNA1, LMP1, and LMP2 transcripts
    • Brooks L, Yao QY, Rickinson AB, Young LS. 1992. Epstein-Barr virus latent gene transcription in nasopharyngeal carcinoma cells:coexpression of EBNA1, LMP1, and LMP2 transcripts. J. Virol. 66:2689-2697.
    • (1992) J. Virol. , vol.66 , pp. 2689-2697
    • Brooks, L.1    Yao, Q.Y.2    Rickinson, A.B.3    Young, L.S.4
  • 2
    • 0026582459 scopus 로고
    • Consistent transcription of the Epstein-Barr virus LMP2 gene in nasopharyngeal carcinoma
    • Busson P, McCoy R, Sadler R, Gilligan K, Tursz T, Raab-Traub N. 1992. Consistent transcription of the Epstein-Barr virus LMP2 gene in nasopharyngeal carcinoma. J. Virol. 66:3257-3262.
    • (1992) J. Virol. , vol.66 , pp. 3257-3262
    • Busson, P.1    McCoy, R.2    Sadler, R.3    Gilligan, K.4    Tursz, T.5    Raab-Traub, N.6
  • 3
    • 54849442316 scopus 로고    scopus 로고
    • Function of latent membrane protein 2A
    • Robertson ES (ed), Caister Academic Press, Poole, United Kingdom.
    • Ikeda MF, Makoto; and Longnecker Richard. 2005. Function of latent membrane protein 2A, p 533-552. In Robertson ES (ed), Epstein-Barr virus. Caister Academic Press, Poole, United Kingdom.
    • (2005) Epstein-Barr virus , pp. 533-552
    • Ikeda, M.1    Makoto, F.2    Richard, L.3
  • 4
    • 0036435166 scopus 로고    scopus 로고
    • Epstein-Barr virus in the pathogenesis of NPC
    • Raab-Traub N. 2002. Epstein-Barr virus in the pathogenesis of NPC. Semin. Cancer Biol. 12:431-441.
    • (2002) Semin. Cancer Biol. , vol.12 , pp. 431-441
    • Raab-Traub, N.1
  • 5
    • 79955374520 scopus 로고    scopus 로고
    • Epstein-Barr virus transforming proteins:biologic properties and contribution to oncogenesis
    • Damania B, Pipas JM (ed), Springer Science+Business Media, LLC, New York, NY.
    • Raab-Traub N. 2009. Epstein-Barr virus transforming proteins:biologic properties and contribution to oncogenesis, p 259-284. In Damania B, Pipas JM (ed), DNA tumor viruses. Springer Science+Business Media, LLC, New York, NY.
    • (2009) DNA tumor viruses , pp. 259-284
    • Raab-Traub, N.1
  • 6
    • 84865119328 scopus 로고    scopus 로고
    • Novel mechanisms of EBV-induced oncogenesis
    • Raab-Traub N. 2012. Novel mechanisms of EBV-induced oncogenesis. Curr. Opin. Virol. 2:453-458.
    • (2012) Curr. Opin. Virol. , vol.2 , pp. 453-458
    • Raab-Traub, N.1
  • 7
    • 0026934033 scopus 로고
    • Epstein-Barr virus, lymphomas and Hodgkin's disease
    • Young LS, Rowe M. 1992. Epstein-Barr virus, lymphomas and Hodgkin's disease. Semin. Cancer Biol. 3:273-284.
    • (1992) Semin. Cancer Biol. , vol.3 , pp. 273-284
    • Young, L.S.1    Rowe, M.2
  • 9
    • 0030754766 scopus 로고    scopus 로고
    • The immunoreceptor tyrosine-based activation motif of Epstein-Barr virus LMP2A is essential for blocking BCR-mediated signal transduction
    • Fruehling S, Longnecker R. 1997. The immunoreceptor tyrosine-based activation motif of Epstein-Barr virus LMP2A is essential for blocking BCR-mediated signal transduction. Virology 235:241-251.
    • (1997) Virology , vol.235 , pp. 241-251
    • Fruehling, S.1    Longnecker, R.2
  • 10
    • 0031661310 scopus 로고    scopus 로고
    • Tyrosine 112 of latent membrane protein 2A is essential for protein tyrosine kinase loading and regulation of Epstein-Barr virus latency
    • Fruehling S, Swart R, Dolwick KM, Kremmer E, Longnecker R. 1998. Tyrosine 112 of latent membrane protein 2A is essential for protein tyrosine kinase loading and regulation of Epstein-Barr virus latency. J. Virol. 72:7796-7806.
    • (1998) J. Virol. , vol.72 , pp. 7796-7806
    • Fruehling, S.1    Swart, R.2    Dolwick, K.M.3    Kremmer, E.4    Longnecker, R.5
  • 12
    • 0034007009 scopus 로고    scopus 로고
    • The Epstein-Barr virus latent membrane protein 2A PY motif recruits WW domaincontaining ubiquitin-protein ligases
    • Ikeda M, Ikeda A, Longan LC, Longnecker R. 2000. The Epstein-Barr virus latent membrane protein 2A PY motif recruits WW domaincontaining ubiquitin-protein ligases. Virology 268:178-191.
    • (2000) Virology , vol.268 , pp. 178-191
    • Ikeda, M.1    Ikeda, A.2    Longan, L.C.3    Longnecker, R.4
  • 13
    • 0036382917 scopus 로고    scopus 로고
    • Lysine-independent ubiquitination of Epstein-Barr virus LMP2A
    • Ikeda M, Ikeda A, Longnecker R. 2002. Lysine-independent ubiquitination of Epstein-Barr virus LMP2A. Virology 300:153-159.
    • (2002) Virology , vol.300 , pp. 153-159
    • Ikeda, M.1    Ikeda, A.2    Longnecker, R.3
  • 14
    • 0035009189 scopus 로고    scopus 로고
    • PY motifs of Epstein-Barr virus LMP2A regulate protein stability and phosphorylation of LMP2Aassociated proteins
    • Ikeda M, Ikeda A, Longnecker R. 2001. PY motifs of Epstein-Barr virus LMP2A regulate protein stability and phosphorylation of LMP2Aassociated proteins. J. Virol. 75:5711-5718.
    • (2001) J. Virol. , vol.75 , pp. 5711-5718
    • Ikeda, M.1    Ikeda, A.2    Longnecker, R.3
  • 15
    • 0033756590 scopus 로고    scopus 로고
    • Latent membrane protein 2A of Epstein-Barr virus binds WW domain E3 protein-ubiquitin ligases that ubiquitinate B-cell tyrosine kinases
    • Winberg G, Matskova L, Chen F, Plant P, Rotin D, Gish G, Ingham R, Ernberg I, Pawson T. 2000. Latent membrane protein 2A of Epstein-Barr virus binds WW domain E3 protein-ubiquitin ligases that ubiquitinate B-cell tyrosine kinases. Mol. Cell. Biol. 20:8526-8535.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 8526-8535
    • Winberg, G.1    Matskova, L.2    Chen, F.3    Plant, P.4    Rotin, D.5    Gish, G.6    Ingham, R.7    Ernberg, I.8    Pawson, T.9
  • 16
    • 84869032266 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein-2A induces ITAM/Syk-and Akt-dependent epithelial migration through α V-integrin membrane translocation
    • Fotheringham JA, Coalson NE, Raab-Traub N. 2012. Epstein-Barr virus latent membrane protein-2A induces ITAM/Syk-and Akt-dependent epithelial migration through α V-integrin membrane translocation. J. Virol. 86:10308-10320.
    • (2012) J. Virol. , vol.86 , pp. 10308-10320
    • Fotheringham, J.A.1    Coalson, N.E.2    Raab-Traub, N.3
  • 17
    • 77955172208 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein-2A-induced DeltaNp63alpha expression is associated with impaired epithelial-cell differentiation
    • Fotheringham JA, Mazzucca S, Raab-Traub N. 2010. Epstein-Barr virus latent membrane protein-2A-induced DeltaNp63alpha expression is associated with impaired epithelial-cell differentiation. Oncogene 29:4287-4296.
    • (2010) Oncogene , vol.29 , pp. 4287-4296
    • Fotheringham, J.A.1    Mazzucca, S.2    Raab-Traub, N.3
  • 18
    • 34548156449 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 2A mediates transformation through constitutive activation of the Ras/PI3-K/Akt Pathway
    • Fukuda M, Longnecker R. 2007. Epstein-Barr virus latent membrane protein 2A mediates transformation through constitutive activation of the Ras/PI3-K/Akt Pathway. J. Virol. 81:9299-9306.
    • (2007) J. Virol. , vol.81 , pp. 9299-9306
    • Fukuda, M.1    Longnecker, R.2
  • 19
    • 0033756107 scopus 로고    scopus 로고
    • Epstein-Barr virus LMP2A transforms epithelial cells, inhibits cell differentiation, and activates Akt
    • Scholle F, Bendt KM, Raab-Traub N. 2000. Epstein-Barr virus LMP2A transforms epithelial cells, inhibits cell differentiation, and activates Akt. J. Virol. 74:10681-10689.
    • (2000) J. Virol. , vol.74 , pp. 10681-10689
    • Scholle, F.1    Bendt, K.M.2    Raab-Traub, N.3
  • 20
    • 44949174077 scopus 로고    scopus 로고
    • Rhesus lymphocryptovirus latent membrane protein 2A activates beta-catenin signaling and inhibits differentiation in epithelial cells
    • Siler CA, Raab-Traub N. 2008. Rhesus lymphocryptovirus latent membrane protein 2A activates beta-catenin signaling and inhibits differentiation in epithelial cells. Virology 377:273-279.
    • (2008) Virology , vol.377 , pp. 273-279
    • Siler, C.A.1    Raab-Traub, N.2
  • 21
    • 13444254201 scopus 로고    scopus 로고
    • Roles of the ITAM and PY motifs of Epstein-Barr virus latent membrane protein 2A in the inhibition of epithelial cell differentiation and activation of β-catenin signaling
    • Morrison JA, Raab-Traub N. 2005. Roles of the ITAM and PY motifs of Epstein-Barr virus latent membrane protein 2A in the inhibition of epithelial cell differentiation and activation of β-catenin signaling. J. Virol. 79:2375-2382.
    • (2005) J. Virol. , vol.79 , pp. 2375-2382
    • Morrison, J.A.1    Raab-Traub, N.2
  • 22
    • 84861312893 scopus 로고    scopus 로고
    • Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) and LMP2A function cooperatively to promote carcinoma development in a mouse carcinogenesis model
    • Shair KH, Bendt KM, Edwards RH, Nielsen JN, Moore DT, Raab-Traub N. 2012. Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) and LMP2A function cooperatively to promote carcinoma development in a mouse carcinogenesis model. J. Virol. 86:5352-5365.
    • (2012) J. Virol. , vol.86 , pp. 5352-5365
    • Shair, K.H.1    Bendt, K.M.2    Edwards, R.H.3    Nielsen, J.N.4    Moore, D.T.5    Raab-Traub, N.6
  • 23
    • 0033825005 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 2A has no growth-altering effects when expressed in differentiating epithelia
    • Longan L, Longnecker R. 2000. Epstein-Barr virus latent membrane protein 2A has no growth-altering effects when expressed in differentiating epithelia. J. Gen. Virol. 81:2245-2252.
    • (2000) J. Gen. Virol. , vol.81 , pp. 2245-2252
    • Longan, L.1    Longnecker, R.2
  • 24
    • 25444443688 scopus 로고    scopus 로고
    • Modelling glandular epithelial cancers in three-dimensional cultures
    • Debnath J, Brugge JS. 2005. Modelling glandular epithelial cancers in three-dimensional cultures. Nat. Rev. Cancer 5:675-688.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 675-688
    • Debnath, J.1    Brugge, J.S.2
  • 25
    • 0037020196 scopus 로고    scopus 로고
    • The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini
    • Debnath J, Mills KR, Collins NL, Reginato MJ, Muthuswamy SK, Brugge JS. 2002. The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini. Cell 111:29-40.
    • (2002) Cell , vol.111 , pp. 29-40
    • Debnath, J.1    Mills, K.R.2    Collins, N.L.3    Reginato, M.J.4    Muthuswamy, S.K.5    Brugge, J.S.6
  • 26
    • 0037603113 scopus 로고    scopus 로고
    • Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in threedimensional basement membrane cultures
    • Debnath J, Muthuswamy SK, Brugge JS. 2003. Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in threedimensional basement membrane cultures. Methods 30:256-268.
    • (2003) Methods , vol.30 , pp. 256-268
    • Debnath, J.1    Muthuswamy, S.K.2    Brugge, J.S.3
  • 27
    • 0242266916 scopus 로고    scopus 로고
    • Akt activation disrupts mammary acinar architecture and enhances proliferation in an mTOR-dependent manner
    • Debnath J, Walker SJ, Brugge JS. 2003. Akt activation disrupts mammary acinar architecture and enhances proliferation in an mTOR-dependent manner. J. Cell Biol. 163:315-326.
    • (2003) J. Cell Biol. , vol.163 , pp. 315-326
    • Debnath, J.1    Walker, S.J.2    Brugge, J.S.3
  • 28
    • 64749094541 scopus 로고    scopus 로고
    • Increasingly transformed MCF-10A cells have a progressively tumor-like phenotype in three-dimensional basement membrane culture
    • Imbalzano KM, Tatarkova I, Imbalzano AN, Nickerson JA. 2009. Increasingly transformed MCF-10A cells have a progressively tumor-like phenotype in three-dimensional basement membrane culture. Cancer Cell Int. 9:7.
    • (2009) Cancer Cell Int. , vol.9 , pp. 7
    • Imbalzano, K.M.1    Tatarkova, I.2    Imbalzano, A.N.3    Nickerson, J.A.4
  • 32
    • 9644279753 scopus 로고    scopus 로고
    • Epstein-Barr virus (EBV) LMP2A mediates B-lymphocyte survival through constitutive activation of the Ras/PI3K/ Akt pathway
    • Portis T, Longnecker R. 2004. Epstein-Barr virus (EBV) LMP2A mediates B-lymphocyte survival through constitutive activation of the Ras/PI3K/ Akt pathway. Oncogene 23:8619-8628.
    • (2004) Oncogene , vol.23 , pp. 8619-8628
    • Portis, T.1    Longnecker, R.2
  • 33
    • 0034854417 scopus 로고    scopus 로고
    • ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini
    • Muthuswamy SK, Li D, Lelievre S, Bissell MJ, Brugge JS. 2001. ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini. Nat. Cell Biol. 3:785-792.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 785-792
    • Muthuswamy, S.K.1    Li, D.2    Lelievre, S.3    Bissell, M.J.4    Brugge, J.S.5
  • 34
    • 0033761806 scopus 로고    scopus 로고
    • Latent membrane protein 2A-mediated effects on the phosphatidylinositol 3-Kinase/Akt pathway
    • Swart R, Ruf IK, Sample J, Longnecker R. 2000. Latent membrane protein 2A-mediated effects on the phosphatidylinositol 3-Kinase/Akt pathway. J. Virol. 74:10838-10845.
    • (2000) J. Virol. , vol.74 , pp. 10838-10845
    • Swart, R.1    Ruf, I.K.2    Sample, J.3    Longnecker, R.4
  • 35
    • 79955532880 scopus 로고    scopus 로고
    • Mutant p53 disrupts MCF-10A cell polarity in three-dimensional culture via epithelial-to-mesenchymal transitions
    • Zhang Y, Yan W, Chen X. 2011. Mutant p53 disrupts MCF-10A cell polarity in three-dimensional culture via epithelial-to-mesenchymal transitions. J. Biol. Chem. 286:16218-16228.
    • (2011) J. Biol. Chem. , vol.286 , pp. 16218-16228
    • Zhang, Y.1    Yan, W.2    Chen, X.3
  • 37
    • 40949148735 scopus 로고    scopus 로고
    • 14-3-3 zeta down-regulates p53 in mammary epithelial cells and confers luminal filling
    • Danes CG, Wyszomierski SL, Lu J, Neal CL, Yang W, Yu D. 2008. 14-3-3 zeta down-regulates p53 in mammary epithelial cells and confers luminal filling. Cancer Res. 68:1760-1767.
    • (2008) Cancer Res. , vol.68 , pp. 1760-1767
    • Danes, C.G.1    Wyszomierski, S.L.2    Lu, J.3    Neal, C.L.4    Yang, W.5    Yu, D.6
  • 38
    • 84866516368 scopus 로고    scopus 로고
    • HuR is necessary for mammary epithelial cell proliferation and polarity at least in part via DeltaNp63
    • doi:10.1371/journal.pone.0045336
    • Yan W, Zhang Y, Zhang J, Cho SJ, Chen X. 2012. HuR is necessary for mammary epithelial cell proliferation and polarity at least in part via DeltaNp63. PLoS One 7:e45336. doi:10.1371/journal.pone.0045336.
    • (2012) PLoS One , vol.7
    • Yan, W.1    Zhang, Y.2    Zhang, J.3    Cho, S.J.4    Chen, X.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.