메뉴 건너뛰기




Volumn 62, Issue 12, 2013, Pages 1840-1849

The high-fat high-fructose hamster as an animal model for niacin's biological activities in humans

Author keywords

HDL C; LDL C; Lipid metabolism; TG

Indexed keywords

ABC TRANSPORTER A1; ADIPONECTIN; APOLIPOPROTEIN A1; FATTY ACID; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MESSENGER RNA; NICOTINIC ACID; TRIACYLGLYCEROL;

EID: 84887997665     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2013.08.001     Document Type: Article
Times cited : (5)

References (55)
  • 1
    • 0033751381 scopus 로고    scopus 로고
    • Mechanism of action of niacin on lipoprotein metabolism
    • V.S. Kamanna, and M.L. Kashyap Mechanism of action of niacin on lipoprotein metabolism Curr Atheroscler Rep 2 1 2000 36 46
    • (2000) Curr Atheroscler Rep , vol.2 , Issue.1 , pp. 36-46
    • Kamanna, V.S.1    Kashyap, M.L.2
  • 2
    • 20544468764 scopus 로고    scopus 로고
    • High-density lipoproteins as therapeutic targets
    • S.J. Nicholls, K.A. Rye, and P.J. Barter High-density lipoproteins as therapeutic targets Curr Opin Lipidol 16 3 2005 345 349
    • (2005) Curr Opin Lipidol , vol.16 , Issue.3 , pp. 345-349
    • Nicholls, S.J.1    Rye, K.A.2    Barter, P.J.3
  • 3
    • 0026021035 scopus 로고
    • Coronary drug project: Experience with niacin. Coronary Drug Project Research Group
    • K.G. Berge, and P.L. Canner Coronary drug project: experience with niacin. Coronary Drug Project Research Group Eur J Clin Pharmacol 40 Suppl. 1 1991 S49 S51
    • (1991) Eur J Clin Pharmacol , vol.40 , Issue.SUPPL. 1
    • Berge, K.G.1    Canner, P.L.2
  • 4
    • 0035969564 scopus 로고    scopus 로고
    • Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease
    • B.G. Brown, X.Q. Zhao, and A. Chait Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease N Engl J Med 345 22 2001 1583 1592
    • (2001) N Engl J Med , vol.345 , Issue.22 , pp. 1583-1592
    • Brown, B.G.1    Zhao, X.Q.2    Chait, A.3
  • 5
    • 0028913839 scopus 로고
    • Types of change in coronary stenosis severity and their relative importance in overall progression and regression of coronary disease. Observations from the FATS Trial. Familial Atherosclerosis Treatment Study
    • discussion 417-408
    • B.G. Brown, L. Hillger, and X.Q. Zhao Types of change in coronary stenosis severity and their relative importance in overall progression and regression of coronary disease. Observations from the FATS Trial. Familial Atherosclerosis Treatment Study Ann N Y Acad Sci 748 1995 407 417 discussion 417-408
    • (1995) Ann N y Acad Sci , vol.748 , pp. 407-417
    • Brown, B.G.1    Hillger, L.2    Zhao, X.Q.3
  • 6
    • 0034644442 scopus 로고    scopus 로고
    • Effect of niacin on lipid and lipoprotein levels and glycemic control in patients with diabetes and peripheral arterial disease: The ADMIT study: A randomized trial. Arterial Disease Multiple Intervention Trial
    • M.B. Elam, D.B. Hunninghake, and K.B. Davis Effect of niacin on lipid and lipoprotein levels and glycemic control in patients with diabetes and peripheral arterial disease: the ADMIT study: a randomized trial. Arterial Disease Multiple Intervention Trial JAMA 284 10 2000 1263 1270
    • (2000) JAMA , vol.284 , Issue.10 , pp. 1263-1270
    • Elam, M.B.1    Hunninghake, D.B.2    Davis, K.B.3
  • 7
    • 84948007950 scopus 로고
    • Beneficial effects of combined colestipol-niacin therapy on coronary atherosclerosis and coronary venous bypass grafts
    • D.H. Blankenhorn, S.A. Nessim, and R.L. Johnson Beneficial effects of combined colestipol-niacin therapy on coronary atherosclerosis and coronary venous bypass grafts JAMA 257 23 1987 3233 3240
    • (1987) JAMA , vol.257 , Issue.23 , pp. 3233-3240
    • Blankenhorn, D.H.1    Nessim, S.A.2    Johnson, R.L.3
  • 8
    • 10044281651 scopus 로고    scopus 로고
    • Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol (ARBITER) 2: A double-blind, placebo-controlled study of extended-release niacin on atherosclerosis progression in secondary prevention patients treated with statins
    • A.J. Taylor, L.E. Sullenberger, and H.J. Lee Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol (ARBITER) 2: a double-blind, placebo-controlled study of extended-release niacin on atherosclerosis progression in secondary prevention patients treated with statins Circulation 110 23 2004 3512 3517
    • (2004) Circulation , vol.110 , Issue.23 , pp. 3512-3517
    • Taylor, A.J.1    Sullenberger, L.E.2    Lee, H.J.3
  • 9
    • 77953121328 scopus 로고    scopus 로고
    • The ARBITER 6-HALTS Trial (Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol 6-HDL and LDL Treatment Strategies in Atherosclerosis): Final results and the impact of medication adherence, dose, and treatment duration
    • T.C. Villines, E.J. Stanek, and P.J. Devine The ARBITER 6-HALTS Trial (Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol 6-HDL and LDL Treatment Strategies in Atherosclerosis): final results and the impact of medication adherence, dose, and treatment duration J Am Coll Cardiol 55 24 2010 2721 2726
    • (2010) J Am Coll Cardiol , vol.55 , Issue.24 , pp. 2721-2726
    • Villines, T.C.1    Stanek, E.J.2    Devine, P.J.3
  • 10
    • 84855171302 scopus 로고    scopus 로고
    • Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy
    • W.E. Boden, J.L. Probstfield, and T. Anderson Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy N Engl J Med 365 24 2011 2255 2267
    • (2011) N Engl J Med , vol.365 , Issue.24 , pp. 2255-2267
    • Boden, W.E.1    Probstfield, J.L.2    Anderson, T.3
  • 11
    • 84887990341 scopus 로고    scopus 로고
    • O'Riordan M. HPS-2 THRIVE misses primary end point: no benefit of niacin/laropiprant. Assessed at on 20 December 2012
    • O'Riordan M. HPS-2 THRIVE misses primary end point: no benefit of niacin/laropiprant. Assessed at http://www.theheart.org/article/1490635.do on 20 December 2012.
  • 12
    • 84859088486 scopus 로고    scopus 로고
    • Is niacin ineffective? Or did AIM-HIGH miss its target?
    • S.J. Nicholls Is niacin ineffective? Or did AIM-HIGH miss its target? Cleve Clin J Med 79 1 2012 38 43
    • (2012) Cleve Clin J Med , vol.79 , Issue.1 , pp. 38-43
    • Nicholls, S.J.1
  • 13
    • 0003293442 scopus 로고    scopus 로고
    • Molecular identification of high and low affinity receptors for nicotinic acid
    • A. Wise, S.M. Foord, and N.J. Fraser Molecular identification of high and low affinity receptors for nicotinic acid J Biol Chem 278 11 2003 9869 9874
    • (2003) J Biol Chem , vol.278 , Issue.11 , pp. 9869-9874
    • Wise, A.1    Foord, S.M.2    Fraser, N.J.3
  • 14
    • 0037352280 scopus 로고    scopus 로고
    • PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect
    • S. Tunaru, J. Kero, and A. Schaub PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect Nat Med 9 3 2003 352 355
    • (2003) Nat Med , vol.9 , Issue.3 , pp. 352-355
    • Tunaru, S.1    Kero, J.2    Schaub, A.3
  • 15
    • 0037470749 scopus 로고    scopus 로고
    • Molecular identification of nicotinic acid receptor
    • T. Soga, M. Kamohara, and J. Takasaki Molecular identification of nicotinic acid receptor Biochem Biophys Res Commun 303 1 2003 364 369
    • (2003) Biochem Biophys Res Commun , vol.303 , Issue.1 , pp. 364-369
    • Soga, T.1    Kamohara, M.2    Takasaki, J.3
  • 16
    • 53249145678 scopus 로고    scopus 로고
    • Effects of a niacin receptor partial agonist, MK-0354, on plasma free fatty acids, lipids, and cutaneous flushing in humans
    • E. Lai, M.G. Waters, and J.R. Tata Effects of a niacin receptor partial agonist, MK-0354, on plasma free fatty acids, lipids, and cutaneous flushing in humans J Clin Lipidol 2 5 2008 375 383
    • (2008) J Clin Lipidol , vol.2 , Issue.5 , pp. 375-383
    • Lai, E.1    Waters, M.G.2    Tata, J.R.3
  • 17
    • 84860273364 scopus 로고    scopus 로고
    • (1aR,5aR)1a,3,5,5a-Tetrahydro-1H-2,3-diaza-cyclopropa[a] pentalene-4-carboxylic acid (MK-1903): A potent GPR109a agonist that lowers free fatty acids in humans
    • P.D. Boatman, B. Lauring, and Schrader TO (1aR,5aR)1a,3,5,5a-Tetrahydro- 1H-2,3-diaza-cyclopropa[a]pentalene-4-carboxylic acid (MK-1903): a potent GPR109a agonist that lowers free fatty acids in humans J Med Chem 55 8 2012 3644 3666
    • (2012) J Med Chem , vol.55 , Issue.8 , pp. 3644-3666
    • Boatman, P.D.1    Lauring, B.2    To, S.3
  • 18
    • 84865330824 scopus 로고    scopus 로고
    • Niacin lipid efficacy is independent of both the niacin receptor GPR109A and free fatty acid suppression
    • Lauring B, Taggart AK, Tata JR, et al. Niacin lipid efficacy is independent of both the niacin receptor GPR109A and free fatty acid suppression. Sci Transl Med 4(148):148ra115.
    • Sci Transl Med , vol.4 , Issue.148
    • Lauring, B.1    Taggart, A.K.2    Tata, J.R.3
  • 19
    • 0032542302 scopus 로고    scopus 로고
    • Efficacy and safety of an extended-release niacin (Niaspan): A long-term study
    • discussion 85U-86U
    • D.M. Capuzzi, J.R. Guyton, and J.M. Morgan Efficacy and safety of an extended-release niacin (Niaspan): a long-term study Am J Cardiol 82 12A 1998 74U 81U discussion 85U-86U
    • (1998) Am J Cardiol , vol.82 , Issue.A12
    • Capuzzi, D.M.1    Guyton, J.R.2    Morgan, J.M.3
  • 20
    • 0037158150 scopus 로고    scopus 로고
    • Efficacy, safety, and tolerability of once-daily niacin for the treatment of dyslipidemia associated with type 2 diabetes: Results of the assessment of diabetes control and evaluation of the efficacy of niaspan trial
    • S.M. Grundy, G.L. Vega, and M.E. McGovern Efficacy, safety, and tolerability of once-daily niacin for the treatment of dyslipidemia associated with type 2 diabetes: results of the assessment of diabetes control and evaluation of the efficacy of niaspan trial Arch Intern Med 162 14 2002 1568 1576
    • (2002) Arch Intern Med , vol.162 , Issue.14 , pp. 1568-1576
    • Grundy, S.M.1    Vega, G.L.2    McGovern, M.E.3
  • 21
    • 61849102939 scopus 로고    scopus 로고
    • Effects of niacin and chromium on the expression of ATP-binding cassette transporter A1 and apolipoprotein A-1 genes in HepG2 cells
    • P. Siripurkpong, and K. Na-Bangchang Effects of niacin and chromium on the expression of ATP-binding cassette transporter A1 and apolipoprotein A-1 genes in HepG2 cells J Nutr Biochem 20 4 2009 261 268
    • (2009) J Nutr Biochem , vol.20 , Issue.4 , pp. 261-268
    • Siripurkpong, P.1    Na-Bangchang, K.2
  • 22
    • 1242322495 scopus 로고    scopus 로고
    • Stimulation of CD36 and the key effector of reverse cholesterol transport ATP-binding cassette A1 in monocytoid cells by niacin
    • T. Rubic, M. Trottmann, and R.L. Lorenz Stimulation of CD36 and the key effector of reverse cholesterol transport ATP-binding cassette A1 in monocytoid cells by niacin Biochem Pharmacol 67 3 2004 411 419
    • (2004) Biochem Pharmacol , vol.67 , Issue.3 , pp. 411-419
    • Rubic, T.1    Trottmann, M.2    Lorenz, R.L.3
  • 23
    • 51649127816 scopus 로고    scopus 로고
    • Extended-release niacin alters the metabolism of plasma apolipoprotein (Apo) A-I and ApoB-containing lipoproteins
    • S. Lamon-Fava, M.R. Diffenderfer, and P.H. Barrett Extended-release niacin alters the metabolism of plasma apolipoprotein (Apo) A-I and ApoB-containing lipoproteins Arterioscler Thromb Vasc Biol 28 9 2008 1672 1678
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , Issue.9 , pp. 1672-1678
    • Lamon-Fava, S.1    Diffenderfer, M.R.2    Barrett, P.H.3
  • 24
    • 0031442321 scopus 로고    scopus 로고
    • Niacin decreases removal of high-density lipoprotein apolipoprotein A-I but not cholesterol ester by Hep G2 cells. Implication for reverse cholesterol transport
    • F.Y. Jin, V.S. Kamanna, and M.L. Kashyap Niacin decreases removal of high-density lipoprotein apolipoprotein A-I but not cholesterol ester by Hep G2 cells. Implication for reverse cholesterol transport Arterioscler Thromb Vasc Biol 17 10 1997 2020 2028
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , Issue.10 , pp. 2020-2028
    • Jin, F.Y.1    Kamanna, V.S.2    Kashyap, M.L.3
  • 25
    • 77951483195 scopus 로고    scopus 로고
    • Evidence that niacin inhibits acute vascular inflammation and improves endothelial dysfunction independent of changes in plasma lipids
    • B.J. Wu, L. Yan, and F. Charlton Evidence that niacin inhibits acute vascular inflammation and improves endothelial dysfunction independent of changes in plasma lipids Arterioscler Thromb Vasc Biol 30 5 2010 968 975
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , Issue.5 , pp. 968-975
    • Wu, B.J.1    Yan, L.2    Charlton, F.3
  • 26
    • 79952240405 scopus 로고    scopus 로고
    • Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells
    • M. Lukasova, C. Malaval, and A. Gille Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells J Clin Invest 121 3 2011 1163 1173
    • (2011) J Clin Invest , vol.121 , Issue.3 , pp. 1163-1173
    • Lukasova, M.1    Malaval, C.2    Gille, A.3
  • 27
    • 77049084050 scopus 로고    scopus 로고
    • Anti-inflammatory effects of nicotinic acid in adipocytes demonstrated by suppression of fractalkine, RANTES, and MCP-1 and upregulation of adiponectin
    • J.E. Digby, E. McNeill, and O.J. Dyar Anti-inflammatory effects of nicotinic acid in adipocytes demonstrated by suppression of fractalkine, RANTES, and MCP-1 and upregulation of adiponectin Atherosclerosis 209 1 2009 89 95
    • (2009) Atherosclerosis , vol.209 , Issue.1 , pp. 89-95
    • Digby, J.E.1    McNeill, E.2    Dyar, O.J.3
  • 28
    • 33748446197 scopus 로고    scopus 로고
    • Adipokines and treatment with niacin
    • S. Westphal, K. Borucki, and E. Taneva Adipokines and treatment with niacin Metabolism 55 10 2006 1283 1285
    • (2006) Metabolism , vol.55 , Issue.10 , pp. 1283-1285
    • Westphal, S.1    Borucki, K.2    Taneva, E.3
  • 29
    • 34447324649 scopus 로고    scopus 로고
    • Extended-release niacin raises adiponectin and leptin
    • S. Westphal, K. Borucki, and E. Taneva Extended-release niacin raises adiponectin and leptin Atherosclerosis 193 2 2007 361 365
    • (2007) Atherosclerosis , vol.193 , Issue.2 , pp. 361-365
    • Westphal, S.1    Borucki, K.2    Taneva, E.3
  • 30
    • 40949153934 scopus 로고    scopus 로고
    • Preferential increase in high-molecular weight adiponectin after niacin
    • S. Westphal, and C. Luley Preferential increase in high-molecular weight adiponectin after niacin Atherosclerosis 198 1 2008 179 183
    • (2008) Atherosclerosis , vol.198 , Issue.1 , pp. 179-183
    • Westphal, S.1    Luley, C.2
  • 31
    • 0032171468 scopus 로고    scopus 로고
    • Lack of predictability of classical animal models for hypolipidemic activity: A good time for mice?
    • B.R. Krause, and H.M. Princen Lack of predictability of classical animal models for hypolipidemic activity: a good time for mice? Atherosclerosis 140 1 1998 15 24
    • (1998) Atherosclerosis , vol.140 , Issue.1 , pp. 15-24
    • Krause, B.R.1    Princen, H.M.2
  • 32
    • 79954995814 scopus 로고    scopus 로고
    • Nicotinic acid has anti-atherogenic and anti-inflammatory properties on advanced atherosclerotic lesions independent of its lipid-modifying capabilities
    • E. Holzhauser, C. Albrecht, and Q. Zhou Nicotinic acid has anti-atherogenic and anti-inflammatory properties on advanced atherosclerotic lesions independent of its lipid-modifying capabilities J Cardiovasc Pharmacol 57 4 2011 447 454
    • (2011) J Cardiovasc Pharmacol , vol.57 , Issue.4 , pp. 447-454
    • Holzhauser, E.1    Albrecht, C.2    Zhou, Q.3
  • 33
    • 55449114841 scopus 로고    scopus 로고
    • Niacin increases HDL by reducing hepatic expression and plasma levels of cholesteryl ester transfer protein in APOE*3Leiden.CETP mice
    • J.W. van der Hoorn, W. de Haan, and J.F. Berbee Niacin increases HDL by reducing hepatic expression and plasma levels of cholesteryl ester transfer protein in APOE*3Leiden.CETP mice Arterioscler Thromb Vasc Biol 28 11 2008 2016 2022
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , Issue.11 , pp. 2016-2022
    • Van Der Hoorn, J.W.1    De Haan, W.2    Berbee, J.F.3
  • 34
    • 0028915911 scopus 로고
    • Lovastatin inhibits diet induced atherosclerosis in F1B Golden Syrian hamsters
    • J. Otto, J.M. Ordovas, and D. Smith Lovastatin inhibits diet induced atherosclerosis in F1B Golden Syrian hamsters Atherosclerosis 114 1 1995 19 28
    • (1995) Atherosclerosis , vol.114 , Issue.1 , pp. 19-28
    • Otto, J.1    Ordovas, J.M.2    Smith, D.3
  • 35
    • 0035929192 scopus 로고    scopus 로고
    • High fat fed hamster, a unique animal model for treatment of diabetic dyslipidemia with peroxisome proliferator activated receptor alpha selective agonists
    • P.R. Wang, Q. Guo, and M. Ippolito High fat fed hamster, a unique animal model for treatment of diabetic dyslipidemia with peroxisome proliferator activated receptor alpha selective agonists Eur J Pharmacol 427 3 2001 285 293
    • (2001) Eur J Pharmacol , vol.427 , Issue.3 , pp. 285-293
    • Wang, P.R.1    Guo, Q.2    Ippolito, M.3
  • 36
    • 78449298399 scopus 로고    scopus 로고
    • Anti-hyperlipidemic and insulin sensitizing activities of fenofibrate reduces aortic lipid deposition in hyperlipidemic Golden Syrian hamster
    • R.A. Srivastava, and S. He Anti-hyperlipidemic and insulin sensitizing activities of fenofibrate reduces aortic lipid deposition in hyperlipidemic Golden Syrian hamster Mol Cell Biochem 345 1-2 2010 197 206
    • (2010) Mol Cell Biochem , vol.345 , Issue.12 , pp. 197-206
    • Srivastava, R.A.1    He, S.2
  • 37
    • 0031920793 scopus 로고    scopus 로고
    • An efficient chromatographic system for lipoprotein fractionation using whole plasma
    • W. Innis-Whitehouse, X. Li, and W.V. Brown An efficient chromatographic system for lipoprotein fractionation using whole plasma J Lipid Res 39 3 1998 679 690
    • (1998) J Lipid Res , vol.39 , Issue.3 , pp. 679-690
    • Innis-Whitehouse, W.1    Li, X.2    Brown, W.V.3
  • 38
    • 15744394674 scopus 로고    scopus 로고
    • Fructose, insulin resistance, and metabolic dyslipidemia
    • H. Basciano, L. Federico, and K. Adeli Fructose, insulin resistance, and metabolic dyslipidemia Nutr Metab (Lond) 2 1 2005 5
    • (2005) Nutr Metab (Lond) , vol.2 , Issue.1 , pp. 5
    • Basciano, H.1    Federico, L.2    Adeli, K.3
  • 39
    • 66449093225 scopus 로고    scopus 로고
    • Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans
    • K.L. Stanhope, J.M. Schwarz, and N.L. Keim Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans J Clin Invest 119 5 2009 1322 1334
    • (2009) J Clin Invest , vol.119 , Issue.5 , pp. 1322-1334
    • Stanhope, K.L.1    Schwarz, J.M.2    Keim, N.L.3
  • 40
    • 0027958084 scopus 로고
    • ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree
    • Y. Nakashima, A.S. Plump, and E.W. Raines ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree Arterioscler Thromb 14 1 1994 133 140
    • (1994) Arterioscler Thromb , vol.14 , Issue.1 , pp. 133-140
    • Nakashima, Y.1    Plump, A.S.2    Raines, E.W.3
  • 41
    • 0029838433 scopus 로고    scopus 로고
    • Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level: A meta-analysis of population-based prospective studies
    • J.E. Hokanson, and M.A. Austin Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level: a meta-analysis of population-based prospective studies J Cardiovasc Risk 3 2 1996 213 219
    • (1996) J Cardiovasc Risk , vol.3 , Issue.2 , pp. 213-219
    • Hokanson, J.E.1    Austin, M.A.2
  • 43
    • 0035980764 scopus 로고    scopus 로고
    • Regulation of lipid metabolism and gene expression by fenofibrate in hamsters
    • Q. Guo, P.R. Wang, and D.P. Milot Regulation of lipid metabolism and gene expression by fenofibrate in hamsters Biochim Biophys Acta 1533 3 2001 220 232
    • (2001) Biochim Biophys Acta , vol.1533 , Issue.3 , pp. 220-232
    • Guo, Q.1    Wang, P.R.2    Milot, D.P.3
  • 44
    • 11844296800 scopus 로고    scopus 로고
    • Efficacy and safety of high-density lipoprotein cholesterol-increasing compounds: A meta-analysis of randomized controlled trials
    • R.S. Birjmohun, B.A. Hutten, and J.J. Kastelein Efficacy and safety of high-density lipoprotein cholesterol-increasing compounds: a meta-analysis of randomized controlled trials J Am Coll Cardiol 45 2 2005 185 197
    • (2005) J Am Coll Cardiol , vol.45 , Issue.2 , pp. 185-197
    • Birjmohun, R.S.1    Hutten, B.A.2    Kastelein, J.J.3
  • 45
    • 0035823531 scopus 로고    scopus 로고
    • Human ABCA1 BAC transgenic mice show increased high density lipoprotein cholesterol and ApoAI-dependent efflux stimulated by an internal promoter containing liver X receptor response elements in intron 1
    • R.R. Singaraja, V. Bocher, and E.R. James Human ABCA1 BAC transgenic mice show increased high density lipoprotein cholesterol and ApoAI-dependent efflux stimulated by an internal promoter containing liver X receptor response elements in intron 1 J Biol Chem 276 36 2001 33969 33979
    • (2001) J Biol Chem , vol.276 , Issue.36 , pp. 33969-33979
    • Singaraja, R.R.1    Bocher, V.2    James, E.R.3
  • 46
    • 33845320131 scopus 로고    scopus 로고
    • Molecular regulation of HDL metabolism and function: Implications for novel therapies
    • D.J. Rader Molecular regulation of HDL metabolism and function: implications for novel therapies J Clin Invest 116 12 2006 3090 3100
    • (2006) J Clin Invest , vol.116 , Issue.12 , pp. 3090-3100
    • Rader, D.J.1
  • 47
    • 84860303700 scopus 로고    scopus 로고
    • Niacin increases HDL biogenesis by enhancing DR4-dependent transcription of ABCA1 and lipidation of apolipoprotein A-I in HepG2 cells
    • L.H. Zhang, V.S. Kamanna, and S.H. Ganji Niacin increases HDL biogenesis by enhancing DR4-dependent transcription of ABCA1 and lipidation of apolipoprotein A-I in HepG2 cells J Lipid Res 53 5 2012 941 950
    • (2012) J Lipid Res , vol.53 , Issue.5 , pp. 941-950
    • Zhang, L.H.1    Kamanna, V.S.2    Ganji, S.H.3
  • 48
    • 77953961808 scopus 로고    scopus 로고
    • Cholesterol efflux potential and antiinflammatory properties of high-density lipoprotein after treatment with niacin or anacetrapib
    • L. Yvan-Charvet, J. Kling, and T. Pagler Cholesterol efflux potential and antiinflammatory properties of high-density lipoprotein after treatment with niacin or anacetrapib Arterioscler Thromb Vasc Biol 30 7 2010 1430 1438
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , Issue.7 , pp. 1430-1438
    • Yvan-Charvet, L.1    Kling, J.2    Pagler, T.3
  • 49
    • 38749110451 scopus 로고    scopus 로고
    • Increased total and high-molecular weight adiponectin after extended-release niacin
    • E.P. Plaisance, P.W. Grandjean, and B.L. Brunson Increased total and high-molecular weight adiponectin after extended-release niacin Metabolism 57 3 2008 404 409
    • (2008) Metabolism , vol.57 , Issue.3 , pp. 404-409
    • Plaisance, E.P.1    Grandjean, P.W.2    Brunson, B.L.3
  • 50
    • 77952515176 scopus 로고    scopus 로고
    • Hypoadiponectinemia: A risk factor for metabolic syndrome
    • O. Renaldi, B. Pramono, and H. Sinorita Hypoadiponectinemia: a risk factor for metabolic syndrome Acta Med Indones 41 1 2009 20 24
    • (2009) Acta Med Indones , vol.41 , Issue.1 , pp. 20-24
    • Renaldi, O.1    Pramono, B.2    Sinorita, H.3
  • 51
    • 22144459031 scopus 로고    scopus 로고
    • Niacin mediates lipolysis in adipose tissue through its G-protein coupled receptor HM74A
    • Y. Zhang, R.J. Schmidt, and P. Foxworthy Niacin mediates lipolysis in adipose tissue through its G-protein coupled receptor HM74A Biochem Biophys Res Commun 334 2 2005 729 732
    • (2005) Biochem Biophys Res Commun , vol.334 , Issue.2 , pp. 729-732
    • Zhang, Y.1    Schmidt, R.J.2    Foxworthy, P.3
  • 52
    • 16644369497 scopus 로고    scopus 로고
    • Niacin noncompetitively inhibits DGAT2 but not DGAT1 activity in HepG2 cells
    • S.H. Ganji, S. Tavintharan, and D. Zhu Niacin noncompetitively inhibits DGAT2 but not DGAT1 activity in HepG2 cells J Lipid Res 45 10 2004 1835 1845
    • (2004) J Lipid Res , vol.45 , Issue.10 , pp. 1835-1845
    • Ganji, S.H.1    Tavintharan, S.2    Zhu, D.3
  • 53
    • 77958100005 scopus 로고    scopus 로고
    • New evidence for nicotinic acid treatment to reduce atherosclerosis
    • F. Montecucco, A. Quercioli, and F. Dallegri New evidence for nicotinic acid treatment to reduce atherosclerosis Expert Rev Cardiovasc Ther 8 10 2010 1457 1467
    • (2010) Expert Rev Cardiovasc Ther , vol.8 , Issue.10 , pp. 1457-1467
    • Montecucco, F.1    Quercioli, A.2    Dallegri, F.3
  • 54
    • 79955769365 scopus 로고    scopus 로고
    • International Union of Basic and Clinical Pharmacology. LXXXII: Nomenclature and classification of hydroxy-carboxylic acid receptors (GPR81, GPR109A, and GPR109B)
    • S. Offermanns, S.L. Colletti, and T.W. Lovenberg International Union of Basic and Clinical Pharmacology. LXXXII: nomenclature and classification of hydroxy-carboxylic acid receptors (GPR81, GPR109A, and GPR109B) Pharmacol Rev 63 2 2011 269 290
    • (2011) Pharmacol Rev , vol.63 , Issue.2 , pp. 269-290
    • Offermanns, S.1    Colletti, S.L.2    Lovenberg, T.W.3
  • 55
    • 84855172236 scopus 로고    scopus 로고
    • Niacin at 56 years of age - Time for an early retirement?
    • R.P. Giugliano Niacin at 56 years of age - time for an early retirement? N Engl J Med 365 24 2011 2318 2320
    • (2011) N Engl J Med , vol.365 , Issue.24 , pp. 2318-2320
    • Giugliano, R.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.