Determination of clonal origin of recurrent hepatocellular carcinoma for personalized therapy and outcomes evaluation: A new strategy for hepatic surgery

Journal of the American College of Surgeons

Volumn 217, Issue 6, 2013, Pages 1054-1062

  Wang, Bin ^a   Xia, Chun Yan ^b   Lau, Wan Yee ^a,c   Lu, Xin Yuan ^a   Dong, Hui ^a   Yu, Wen Long ^a   Jin, Guang Zhi ^a   Cong, Wen Ming ^a   Wu, Meng Chao ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c Prince of Wales Hospital   (Hong Kong)

Author keywords

Abbreviations and Acronyms; HCC; hepatocellular carcinoma; IM; intrahepatic metastasis; LOH; loss of heterozygosity; MO; multicentric occurrence; PCR; polymerase chain reaction; recurrent hepatocellular carcinoma; RHCC

Indexed keywords

ADULT; ARTICLE; CANCER RECURRENCE; CANCER SIZE; CANCER SURGERY; CANCER SURVIVAL; CHRONIC LIVER DISEASE; CLINICAL ARTICLE; CLINICAL FEATURE; FEMALE; HETEROZYGOSITY LOSS; HISTOPATHOLOGY; HUMAN; LIVER CELL CARCINOMA; LONG TERM CARE; MALE; MICRODISSECTION; OVERALL SURVIVAL; PATIENT SELECTION; PERSONALIZED MEDICINE; PRIORITY JOURNAL; RECURRENCE FREE SURVIVAL; RECURRENT HEPATOCELLULAR CARCINOMA;

HCC; HEPATOCELLULAR CARCINOMA; IM; INTRAHEPATIC METASTASIS; LOH; LOSS OF HETEROZYGOSITY; MO; MULTICENTRIC OCCURRENCE; PCR; POLYMERASE CHAIN REACTION; RECURRENT HEPATOCELLULAR CARCINOMA; RHCC;

ADULT; CARCINOMA, HEPATOCELLULAR; CLONE CELLS; FEMALE; GENETIC MARKERS; HEPATECTOMY; HUMANS; INDIVIDUALIZED MEDICINE; LIVER NEOPLASMS; LOSS OF HETEROZYGOSITY; MALE; MICROSATELLITE REPEATS; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 84887915180     PISSN: 10727515     EISSN: 18791190     Source Type: Journal    
DOI: 10.1016/j.jamcollsurg.2013.07.402     Document Type: Article

References (35)

1. A. Jemal, F. Bray, and M.M. Center Global cancer statistics CA Cancer J Clin 61 2011 69 90
2. W.M. Cong, H. Dong, and B. Wang Clinicopathological features and originated model of postoperative recurrent hepatocellular carcinoma Chin J Pract Surg 29 2009 71 73
3. N. Portolani, A. Coniglio, and S. Ghidoni Early and late recurrence after liver resection for hepatocellular carcinoma: prognostic and therapeutic implications Ann Surg 243 2006 229 235
4. S. Arii, K. Teramoto, and T. Kawamura Characteristics of recurrent hepatocellular carcinoma in Japan and our surgical experience J Hepatobiliary Pancreat Surg 8 2001 397 403
5. W. Cong, M. Wu, H. Chen, and X. Zhang Studies on the clinical significance of the clonal origins of recurrent hepatocellular carcinoma Chin Med Sci J 7 1992 101 104
6. R.T. Poon, S.T. Fan, and I.O. Ng Different risk factors and prognosis for early and late intrahepatic recurrence after resection of hepatocellular carcinoma Cancer 89 2000 500 507
7. S. Ariizumi, K. Takasaki, and M. Yamamoto Histopathologic differentiation of the main nodule determines outcome after hepatic resection for synchronous multicentric hepatocellular carcinomas Hepatogastroenterology 51 2004 500 504
8. Y. Matsumoto, H. Fujii, M. Matsuda, and H. Kono Multicentric occurrence of hepatocellular carcinoma: diagnosis and clinical significance J Hepatobiliary Pancreat Surg 8 2001 435 440
9. I. Utsunomiya Pathological study on multicentric occurrence of hepatocellular carcinoma Kurume Med J 52 2005 133 138
10. L. Wilkens, M. Bredt, and P. Flemming Differentiation of multicentric origin from intra-organ metastatic spread of hepatocellular carcinomas by comparative genomic hybridization J Pathol 192 2000 43 51
11. S. Nomoto, T. Kinoshita, and K. Kato Hypermethylation of multiple genes as clonal markers in multicentric hepatocellular carcinoma Br J Cancer 97 2007 1260 1265
12. Q. Zhao, C.Q. Su, and H. Dong Hepatocellular carcinoma and hepatic adenocarcinosarcoma in a patient with hepatitis B virus-related cirrhosis Semin Liver Dis 30 2010 107 112
13. S.F. Ding, R.P. Jalleh, and C.B. Wood Different DNA changes in primary and recurrent hepatocellular carcinoma Gut 33 1992 1433 1435
14. K.B. Hodges, O.W. Cummings, and R. Saxena Clonal origin of multifocal hepatocellular carcinoma Cancer 116 2010 4078 4085
15. I.O. Ng, X.Y. Guan, and R.T. Poon Determination of the molecular relationship between multiple tumour nodules in hepatocellular carcinoma differentiates multicentric origin from intrahepatic metastasis J Pathol 199 2003 345 353
16. H. Tsuda, T. Oda, M. Sakamoto, and S. Hirohashi Different pattern of chromosomal allele loss in multiple hepatocellular carcinomas as evidence of their multifocal origin Cancer Res 52 1992 1504 1509
17. X.Y. Lu, T. Xi, and W.Y. Lau Pathobiological features of small hepatocellular carcinoma: correlation between tumor size and biological behavior J Cancer Res Clin Oncol 137 2011 567 575
18. W.M. Cong, A. Bakker, and P.A. Swalsky Multiple genetic alterations involved in the tumorigenesis of human cholangiocarcinoma: a molecular genetic and clinicopathological study J Cancer Res Clin Oncol 127 2001 187 192
19. S.P. Li, H.Y. Wang, and J.Q. Li Genome-wide analyses on loss of heterozygosity in hepatocellular carcinoma in Southern China J Hepatol 34 2001 840 849
20. H. Nagai, P. Pineau, and P. Tiollais Comprehensive allelotyping of human hepatocellular carcinoma Oncogene 14 1997 2927 2933
21. Y.W. Lin, H.S. Lee, and C.H. Chen Clonality analysis of multiple hepatocellular carcinomas by loss of heterozygosity pattern determined by chromosomes 16q and 13q J Gastroenterol Hepatol 20 2005 536 546
22. O. Morimoto, H. Nagano, and M. Sakon Diagnosis of intrahepatic metastasis and multicentric carcinogenesis by microsatellite loss of heterozygosity in patients with multiple and recurrent hepatocellular carcinomas J Hepatol 39 2003 215 221
23. R. Tung-Ping Poon, S.T. Fan, and J. Wong Risk factors, prevention, and management of postoperative recurrence after resection of hepatocellular carcinoma Ann Surg 232 2000 10 24
24. G.H. Choi, D.H. Kim, and C.M. Kang Prognostic factors and optimal treatment strategy for intrahepatic nodular recurrence after curative resection of hepatocellular carcinoma Ann Surg Oncol 15 2008 618 629
25. J. Wang, Q. Li, and Y. Sun Clinicopathologic features between multicentric occurrence and intrahepatic metastasis of multiple hepatocellular carcinomas related to HBV Surg Oncol 18 2009 25 30
26. Q. Li, J. Wang, and J.T. Juzi Clonality analysis for multicentric origin and intrahepatic metastasis in recurrent and primary hepatocellular carcinoma J Gastrointest Surg 12 2008 1540 1547
27. S.A. Shah, S.P. Cleary, and A.C. Wei Recurrence after liver resection for hepatocellular carcinoma: risk factors, treatment, and outcomes Surgery 141 2007 330 339
28. M. Shimada, T. Hamatsu, and Y. Yamashita Characteristics of multicentric hepatocellular carcinomas: comparison with intrahepatic metastasis World J Surg 25 2001 991 995
29. M. Yasui, A. Harada, and T. Nonami Potentially multicentric hepatocellular carcinoma: clinicopathologic characteristics and postoperative prognosis World J Surg 21 1997 860 864
30. E. Gras, X. Matias-Guiu, and L. Catasus Application of microsatellite PCR techniques in the identification of mixed up tissue specimens in surgical pathology J Clin Pathol 53 2000 238 240
31. J.D. Pfeifer, B. Zehnbauer, and J. Payton The changing spectrum of DNA-based specimen provenance testing in surgical pathology Am J Clin Pathol 135 2011 132 138
32. C.M. Wong, J.M. Lee, and T.C. Lau Clinicopathological significance of loss of heterozygosity on chromosome 13q in hepatocellular carcinoma Clin Cancer Res 8 2002 2266 2272
33. R. Tateishi, S. Shiina, and M. Akahane Frequency, risk factors and survival associated with an intrasubsegmental recurrence after radiofrequency ablation for hepatocellular carcinoma PLoS One 8 2013 e59040
34. Y.C. Shen, C. Hsu, and L.T. Chen Adjuvant interferon therapy after curative therapy for hepatocellular carcinoma (HCC): a meta-regression approach J Hepatol 52 2010 889 894
35. Y. Yu, Q. Lang, and Z. Chen The efficacy for unresectable hepatocellular carcinoma may be improved by transcatheter arterial chemoembolization in combination with a traditional Chinese herbal medicine formula: a retrospective study Cancer 115 2009 5132 5138