Access to a new class of biologically active quinoline based 1,2,4-triazoles

European Journal of Medicinal Chemistry

Volumn 71, Issue , 2014, Pages 24-30

  Patel, Rahul V ^a   Park, Se Won ^a  

^a Konkuk University   (South Korea)

Author keywords

1,2,4 Triazole; Antimicrobial activity; Benzothiazole; Quinoline; Naphthyl isothiocyanate

Indexed keywords

1,2,4 TRIAZOL 3 YLTHIO ACETAMIDE; 1,2,4 TRIAZOLE DERIVATIVE; 2 (4 NAPHTHALEN 1 YL) 5 (QUINOLIN 6 YL) 4H 1,2,4 TRIAZOL 3 YLTHIO]ACETAMIDE; AMPICILLIN; ANTIINFECTIVE AGENT; BENZOTHIAZOLE; FLUCONAZOLE; GENTAMICIN; N (6 ACETAMIDOBENZO[D]THIAZOL 2 YL) 2 [4 (NAPHTHALEN 1 YL) 5 (QUINOLIN 6 YL) 4H 1,2,4 TRIAZOL 3 YLTHIO]ACETAMIDE; N (6 BROMOBENZO[D]THIAZOL 2 YL) 2 [4 (NAPHTHALEN 1 YL) 5 (QUINOLIN 6 YL) 4H 1,2,4 TRIAZOL 3 YLTHIO]ACETAMIDE; N (6 CHLOROBENZO[D]THIAZOL 2 YL) 2 [4 (NAPHTHALEN 1 YL) 5 (QUINOLIN 6 YL) 4H 1,2,4 TRIAZOL 3 YLTHIO]ACETAMIDE; N (6 CYANOBENZO[D]THIAZOL 2 YL) 2 [4 (NAPHTHALEN 1 YL) 5 (QUINOLIN 6 YL) 4H 1,2,4 TRIAZOL 3 YLTHIO]ACETAMIDE; N (6 ETHOXYBENZO[D]THIAZOL 2 YL) 2 [4 (NAPHTHALEN 1 YL) 5 (QUINOLIN 6 YL) 4H 1,2,4 TRIAZOL 3 YLTHIO]ACETAMIDE; N (6 FLUOROBENZO[D]THIAZOL 2 YL) 2 [4 (NAPHTHALEN 1 YL) 5 (QUINOLIN 6 YL) 4H 1,2,4 TRIAZOL 3 YLTHIO]ACETAMIDE; N (6 IODOBENZO[D]THIAZOL 2 YL) 2 [4 (NAPHTHALEN 1 YL) 5 (QUINOLIN 6 YL) 4H 1,2,4 TRIAZOL 3 YLTHIO]ACETAMIDE; N (6 METHOXYBENZO[D]THIAZOL 2 YL) 2 [4 (NAPHTHALEN 1 YL) 5 (QUINOLIN 6 YL) 4H 1,2,4 TRIAZOL 3 YLTHIO]ACETAMIDE; N (6 METHYLBENZO[D]THIAZOL 2 YL) 2 [4 (NAPHTHALEN 1 YL) 5 (QUINOLIN 6 YL) 4H 1,2,4 TRIAZOL 3 YLTHIO]ACETAMIDE; N (BENZO[D]THIAZOL 2 YL) 2 [4 (NAPHTHALEN 1 YL) 5 (QUINOLIN 6 YL) 4H 1,2,4 TRIAZOL 3 YLTHIO]ACETAMIDE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTICLE; ASPERGILLUS NIGER; BACTERIAL STRAIN; CANDIDA ALBICANS; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENCY; DRUG SYNTHESIS; ESCHERICHIA COLI; FUNGAL STRAIN; IN VITRO STUDY; INFRARED RADIATION; KLEBSIELLA PNEUMONIAE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHARMACOPHORE; PROTON NUCLEAR MAGNETIC RESONANCE; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION;

1,2,4-TRIAZOLE; ANTIMICROBIAL ACTIVITY; BENZOTHIAZOLE; QUINOLINE; Α-NAPHTHYL ISOTHIOCYANATE;

ANTI-INFECTIVE AGENTS; BACTERIA; BACTERIAL INFECTIONS; FUNGI; HUMANS; MICROBIAL SENSITIVITY TESTS; MYCOSES; QUINOLINES; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

EID: 84887747760     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.10.059     Document Type: Article

References (21)

1. C.F. Gilks Br. Med. Bull. 54 1998 383 393
2. V. Samaras, P.I. Rafailidis, E.G. Mourtzoukou, G. Peppas, and M.E. Falagas J. Infect. Dev. Countries 4 2010 267 281
3. S. Shoham, and K.A. Marr Future Microbiol. 7 2012 639 655
4. WHO, World Health Organization, http://www.who.int/en/.
5. G.R. Thompson, J. Cadena, and T.F. Patterson Clin. Chest Med. 30 2009 203 215
6. Z.A. Kanafani, and J.R. Perfect Clin. Infect. Dis. 46 2008 120 128
7. R.V. Patel, P.K. Patel, P. Kumari, D.P. Rajani, and K.H. Chikhalia Eur. J. Med. Chem. 53 2012 41 51
8. R. Kharb, and H. Kaur Int. Res. J. Pharm. 4 2013 63 69
9. K. Kaur, M. Jain, R.P. Reddy, and R. Jain Eur. J. Med. Chem. 45 2010 3245 3264
10. V.R. Solomon, and H. Lee Curr. Med. Chem. 18 2011 1488 1508
11. P.M. Hawkey, and D.A. Lewis Medical Bacteriology - a Practical Approach 1994 Oxford University Press United Kingdom 181 194
12. M. Wang, M. Gao, B.H. Mock, K.D. Miller, G.W. Sledge, G.D. Hutchinsa, and Q.H. Zhenga Bioorg. Med. Chem. 14 2006 8599 8607
13. A. Rana, N. Siddiqui, S.A. Khan, S.E. Haque, and M.A. Bhat Eur. J. Med. Chem. 43 2008 1114 1122
14. G. Turan-Zitouni, S. Demirayak, A. Ozdemir, Z.A. Kaplancikli, and M.T. Yildiz Eur. J. Med. Chem. 39 2003 267 272
15. K.M. Amin, D.E.A. Rahman, and Y.A. Al-Eryani Med. Chem. 16 2008 5377 5388
16. C.R. Rasmussen, F.J. Villani, L.E. Weaner Jr., B.E. Reynolds, A.R. Hood, L.R. Hecker, S.O. Nortey, A. Hanslin, M.J. Costanzo, E.T. Powell, and A.J. Molinari Synthesis 1988 456 459
17. R.L. Frank, and P.V. Smith Org. Synth. Coll. Vol. 3 1955 735
18. J. Cymerman-Craig, M. Moyle, and R.A. White Org. Synth. Coll. Vol. 4 1963 700
19. R.V. Patel, P. Kumari, and K.H. Chikhalia Med. Chem. 9 2013 596 607
20. D.L.M. Rosa, H.W. Kim, E. Gunic, C. Jenket, U. Boyle, Y.H. Koh, I. Korboukh, M. Allan, W. Zhang, H. Chen, W. Xu, S. Nilar, N. Yao, R. Hamatake, S.A. Lang, Z. Hong, Z. Zhang, and J.L. Girardet Bioorg. Med. Chem. Lett. 16 2006 4444 4449
21. R.V. Patel, P. Kumari, D.P. Rajani, and K.H. Chikhalia Med. Chem. Res. 22 2013 195 210