Distinguishing T-cell large granular lymphocytic leukemia from reactive conditions. Laboratory tools and challenges in their use.

Surgical Pathology Clinics

Volumn 6, Issue 4, 2013, Pages 631-639

  Neff, Jadee L ^a   Howard, Matthew T ^a   Morice, William G ^a  

^a MAYO CLINIC   (United States)

Author keywords

Differential diagnosis; Intrasinusoidal bone marrow infiltrates; KIR flow cytometry; Large granular lymphocytes; Neoplasms of cytotoxic lymphocytes; T LGL

Indexed keywords

ALEMTUZUMAB; CD2 ANTIGEN; CD3 ANTIGEN; CORTICOSTEROID; CYCLOPHOSPHAMIDE; GRANZYME B; METHOTREXATE; STAT3 PROTEIN;

AGGRESSIVE NK CELL LEUKEMIA; ANEMIA; BONE MARROW; BONE MARROW BIOPSY; BONE MARROW EXAMINATION; CD4 CD8 RATIO; CELL TYPE; CELLULAR IMMUNITY; CLINICAL FEATURE; CLONAL VARIATION; CYTOPATHOLOGY; CYTOPENIA; CYTOPLASM; CYTOTOXIC LYMPHOCYTE; CYTOTOXIC T LYMPHOCYTE; DIFFERENTIAL DIAGNOSIS; ERYTHROPOIESIS; FLOW CYTOMETRY; GENE REARRANGEMENT; GENETIC ANALYSIS; GIEMSA STAIN; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; ISOCHROMOSOME; LABORATORY TEST; LARGE GRANULAR LYMPHOCYTE; LARGE GRANULAR LYMPHOCYTE LEUKEMIA; LONG TERM SURVIVAL; LYMPHOCYTE; LYMPHOCYTE COUNT; LYMPHOCYTOSIS; LYMPHOID CELL; MEMORY T LYMPHOCYTE; MUTATIONAL ANALYSIS; MYELODYSPLASTIC SYNDROME; NEUTROPENIA; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; REVIEW; RHEUMATOID ARTHRITIS; T CELL LEUKEMIA; T CELL LYMPHOMA; T LYMPHOCYTE; T LYMPHOCYTE RECEPTOR GENE; TRISOMY 8;

EID: 84887628211     PISSN: 18759181     EISSN: 18759157     Source Type: Journal    
DOI: 10.1016/j.path.2013.08.009     Document Type: Review

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