T/NK large granular lymphocyte leukemia and coexisting monoclonal B-cell lymphocytosis-like proliferations an unrecognized and frequent association

American Journal of Clinical Pathology

Volumn 133, Issue 6, 2010, Pages 936-941

  Howard, Matthew T ^a   Bejanyan, Nelli ^b   Maciejewski, Jaroslaw P ^b   Hsi, Eric D ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b TAUSSIG CANCER INSTITUTE   (United States)

Author keywords

B cell dyscrasias; Flow cytometry; Lymphoproliferations; Lymphoproliferative disorders; T NK large granular lymphocyte leukemia

Indexed keywords

ADULT; ARTICLE; B CELL LYMPHOCYTOSIS; B LYMPHOCYTE; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LARGE GRANULAR LYMPHOCYTE LEUKEMIA; LYMPHOCYTOSIS; MAJOR CLINICAL STUDY; MALE; NATURAL KILLER CELL; NATURAL KILLER LARGE GRANULAR LYMPHOCYTE LEUKEMIA; PRIORITY JOURNAL; T CELL LARGE GRANULAR LYMPHOCYTE LEUKEMIA; T LYMPHOCYTE; TUMOR GROWTH; AGED; IMMUNOLOGY; LYMPHOCYTE COUNT; MIDDLE AGED; PATHOLOGY; RETROSPECTIVE STUDY;

ADULT; AGED; B-LYMPHOCYTES; FEMALE; FLOW CYTOMETRY; HUMANS; KILLER CELLS, NATURAL; LEUKEMIA, LARGE GRANULAR LYMPHOCYTIC; LYMPHOCYTE COUNT; LYMPHOCYTOSIS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; T-LYMPHOCYTES;

EID: 77952992101     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1309/AJCPIIL1Y5QXTIBP     Document Type: Article

References (16)

1. Rawstron AC, Bennett FL, O'Connor SJM, et al. Monoclonal B-cell lymphocytosis and chronic lymphocytic leukemia. N Engl J Med. 2008;359:575-583.
2. Rawstron AC, Yuille MR, Fuller J, et al. Inherited predisposition to CLL is detectable as subclinical monoclonal B-lymphocyte expansion. Blood. 2002;100:2289-2290.
3. Marti GE, Carter P, Abbasi F, et al. B-cell monoclonal lymphocytosis and B-cell abnormalities in the setting of familial B-cell chronic lymphocytic leukemia. Cytometry B Clin Cytom. 2003;52:1-12.
4. Marti GE, Rawstron AC, Ghia P, et al. Diagnostic criteria for monoclonal B-cell lymphocytosis. Br J Haematol. 2005;130:325-332.
5. Viny AD, Lichtin A, Pohlman B, et al. Chronic B-cell dyscrasias are an important clinical feature of T-LGLL leukemia. Leuk Lymphoma. 2008;49:932-938.
6. β antibodies. Am J Clin Pathol. 2003;120:785-794.
7. Semenzato G, Zambello R, Starkebaum G, et al. The lymphoproliferative disease of granular lymphocytes: updated criteria for diagnosis. Blood. 1997;89:256-260.
8. Wlodarski MW, Schade AE, Maciejewski JP. T-large granular lymphocyte leukemia: current molecular concepts. Hematology. 2006;11:245-256.
9. Swerdlow SH, Campo E, Harris NL, et al, eds. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. Lyon, France: IARC Press; 2008:272-275.
10. Hsi ED, Hoeltge G, Tubbs RR. Biclonal chronic lymphocytic leukemia. Am J Clin Pathol. 2000;113:798-804.
11. Lamy T, Loughren TP. Current concepts: large granular lymphocyte leukemia. Blood Rev. 1999;13:230-240.
12. Witzig TE, Wahner-Roedler DL. Heavy chain disease. Curr Treat Options Oncol. 2002;3:247-254.
13. Galanti LM, Doyen C, Vander Maelen C, et al. Biological diagnosis of a gamma-1-heavy chain disease in an asymptomatic patient. Eur J Haematol. 1995;54:202-204.
14. Fermand JP, Brouet JC. Heavy-chain diseases. Hematol Oncol Clin North Am. 1999;13:1281-1294.
15. Weinberg JB, Volkheimer AD, Chen Y, et al. Clinical and molecular predictors of disease severity and survival in chronic lymphocytic leukemia [published correction appears in Am J Hematol. 2008;83:90]. Am J Hematol. 2007;82:1063-1070.
16. Mueller A, O'Rourke J, Chu P, et al. The role of antigenic drive and tumor-infiltrating accessory cells in the pathogenesis of Helicobacter-induced mucosa-associated lymphoid tissue lymphoma. Am J Pathol. 2005;167:797-812.