-
1
-
-
34248160010
-
Pandrug-resistant Gram-negative bacteria: The dawn of the post-antibiotic era
-
Falagas, M. E.; Bliziotis, I. A. Pandrug-resistant Gram-negative bacteria: The dawn of the post-antibiotic era. Int. J. Antimicrob. Agents 2007, 29, 630-636.
-
(2007)
Int. J. Antimicrob. Agents
, vol.29
, pp. 630-636
-
-
Falagas, M.E.1
Bliziotis, I.A.2
-
2
-
-
84969301493
-
A cheap and effective anti-Mdr/Xdr/Tdr Tb drug is already available
-
doi: 10. 4172/2167-0501. 1000e137
-
Amaral, L.; Udwadia, Z. F.; van Soolingen, D. A cheap and effective anti-Mdr/Xdr/Tdr Tb drug is already available. Biochem. Pharmacol. J. 2012, doi: 10. 4172/2167-0501. 1000e137.
-
(2012)
Biochem. Pharmacol. J.
-
-
Amaral, L.1
Udwadia, Z.F.2
van Soolingen, D.3
-
3
-
-
84866532211
-
Why and how the old neuroleptic thioridazine cures the XDR-TB patient
-
Amaral, L.; Molnar, J. Why and how the old neuroleptic thioridazine cures the XDR-TB patient. Pharmaceuticals 2012, 5, 1021-1031.
-
(2012)
Pharmaceuticals
, vol.5
, pp. 1021-1031
-
-
Amaral, L.1
Molnar, J.2
-
4
-
-
84870330683
-
The added effect of Thioridazine in treatment of resistant TB
-
Amaral, L.; Udwadia, Z.; Abbate, E.; van Soolingen, D. The added effect of Thioridazine in treatment of resistant TB. Int. J. Tuberc. Lung Dis. 2012, 16, 1706-1708.
-
(2012)
Int. J. Tuberc. Lung Dis.
, vol.16
, pp. 1706-1708
-
-
Amaral, L.1
Udwadia, Z.2
Abbate, E.3
van Soolingen, D.4
-
5
-
-
38349170156
-
Treatment of health-careassociated infections caused by Gram-negative bacteria: A consensus statement
-
Chopra, I.; Schofield, C.; Everett, M.; O'Neill, A.; Miller, K.; Wilcox, M.; Frère, J.-M.; Dawson, M.; Czaplewski, L.; Urleb, U.; et al. Treatment of health-careassociated infections caused by Gram-negative bacteria: A consensus statement. Lancet Infect. Dis. 2008, 8, 133-139.
-
(2008)
Lancet Infect. Dis.
, vol.8
, pp. 133-139
-
-
Chopra, I.1
Schofield, C.2
Everett, M.3
O'Neill, A.4
Miller, K.5
Wilcox, M.6
Frère, J.-M.7
Dawson, M.8
Czaplewski, L.9
Urleb, U.10
-
6
-
-
0027073297
-
The antimicrobial activity of non-antibiotics. Report from a congress on the antimicrobial effect of drugs other than antibiotics on bacteria, viruses, protozoa, and other organisms
-
Kristiansen, J. E. The antimicrobial activity of non-antibiotics. Report from a congress on the antimicrobial effect of drugs other than antibiotics on bacteria, viruses, protozoa, and other organisms. APMIS. Suppl. 1992, 30, 7-14.
-
(1992)
APMIS. Suppl.
, vol.30
, pp. 7-14
-
-
Kristiansen, J.E.1
-
8
-
-
0030801767
-
The potential management of resistant infections with non-antibiotics
-
Kristiansen, J. E.; Amaral, L. The potential management of resistant infections with non-antibiotics. J. Antimicrob. Chemother. 1997, 40, 319-327.
-
(1997)
J. Antimicrob. Chemother.
, vol.40
, pp. 319-327
-
-
Kristiansen, J.E.1
Amaral, L.2
-
9
-
-
0017037937
-
Antibacterial activities of ambodryl and benadryl
-
Dastidar, S. G.; Saha, P. K.; Sanyamat, B.; Chakrabarty, A. N. Antibacterial activities of ambodryl and benadryl. J. Appl. Bact. 1976, 41, 209-214.
-
(1976)
J. Appl. Bact.
, vol.41
, pp. 209-214
-
-
Dastidar, S.G.1
Saha, P.K.2
Sanyamat, B.3
Chakrabarty, A.N.4
-
10
-
-
0031929640
-
Antimicrobial activity of the antiinflammatory agent diclofenac sodium
-
Annadurai, S.; Basu, S.; Ray, S.; Dastidar, S. G.; Chakrabarty, A. N. Antimicrobial activity of the antiinflammatory agent diclofenac sodium. Indian J. Exp. Biol. 1998, 36, 86-90.
-
(1998)
Indian J. Exp. Biol.
, vol.36
, pp. 86-90
-
-
Annadurai, S.1
Basu, S.2
Ray, S.3
Dastidar, S.G.4
Chakrabarty, A.N.5
-
11
-
-
0142056162
-
Amlodipine: A cardiovascular drug with powerful antimicrobial property
-
Kumar, K. A.; Ganguly, K.; Mazumdar, K.; Dutta, N. K.; Dastidar, S. G.; Chakrabarty, A. N. Amlodipine: A cardiovascular drug with powerful antimicrobial property. Acta Microbiol. Pol. 2003, 52, 285-292.
-
(2003)
Acta Microbiol. Pol.
, vol.52
, pp. 285-292
-
-
Kumar, K.A.1
Ganguly, K.2
Mazumdar, K.3
Dutta, N.K.4
Dastidar, S.G.5
Chakrabarty, A.N.6
-
12
-
-
0041784908
-
Antimicrobial potentiality of a new non-antibiotic: The cardiovascular drug oxyfedrine hydrochloride
-
Mazumdar, K.; Ganguly, K.; Kumar, K. A.; Dutta, N. K.; Chakrabarty, A. N.; Dastidar, S. G. Antimicrobial potentiality of a new non-antibiotic: The cardiovascular drug oxyfedrine hydrochloride. Microbiol. Res. 2003, 158, 259-264.
-
(2003)
Microbiol. Res.
, vol.158
, pp. 259-264
-
-
Mazumdar, K.1
Ganguly, K.2
Kumar, K.A.3
Dutta, N.K.4
Chakrabarty, A.N.5
Dastidar, S.G.6
-
13
-
-
79953210160
-
Antibacterial Activity of Artificial Phenothiazines and Isoflavones from Plants
-
In, VI; Springer: Berlin/Heidelberg, Germany
-
Dasgupta, A.; Dastidar, S. G.; Shiratki, Y.; Motohashi, N. Antibacterial Activity of Artificial Phenothiazines and Isoflavones from Plants. In Bioactive Heterocycles VI; Springer: Berlin/Heidelberg, Germany, 2008; Volume 15, pp. 67-132.
-
(2008)
Bioactive Heterocycles
, vol.15
, pp. 67-132
-
-
Dasgupta, A.1
Dastidar, S.G.2
Shiratki, Y.3
Motohashi, N.4
-
14
-
-
0018718216
-
Experiments to illustrate the effect of chlorpromazine on the permeability of the bacterial cell wall
-
Kristiansen, J. E. Experiments to illustrate the effect of chlorpromazine on the permeability of the bacterial cell wall. Acta Pathol. Microbiol. Scand. B 1979, 87, 317-319.
-
(1979)
Acta Pathol. Microbiol. Scand. B
, vol.87
, pp. 317-319
-
-
Kristiansen, J.E.1
-
15
-
-
0022997767
-
Chlorpromazine as permeabilizer and reagent for detection of microbial peroxidase and peroxidaselike activities
-
Galeazzi, L.; Turchetti, G.; Grilli, G.; Groppa, G.; Giunta, S. Chlorpromazine as permeabilizer and reagent for detection of microbial peroxidase and peroxidaselike activities. Appl. Environ. Microbiol. 1986, 52, 1433-1435.
-
(1986)
Appl. Environ. Microbiol.
, vol.52
, pp. 1433-1435
-
-
Galeazzi, L.1
Turchetti, G.2
Grilli, G.3
Groppa, G.4
Giunta, S.5
-
16
-
-
0025850483
-
Effects of chlorpromazine on the cell envelope proteins of Echerichia coli
-
Amaral, L.; Lorian, V. Effects of chlorpromazine on the cell envelope proteins of Echerichia coli. Antimicrob. Agents Chemother. 1991, 35, 1923-1924.
-
(1991)
Antimicrob. Agents Chemother.
, vol.35
, pp. 1923-1924
-
-
Amaral, L.1
Lorian, V.2
-
17
-
-
0034115335
-
The effect of chlorpromazine on the outer cell wall constituents of Salmonella typhimurium ensuring resistance to the drug
-
Amaral, L.; Kristiansen, J. E.; Thomsen, V. F.; Markowich, B. The effect of chlorpromazine on the outer cell wall constituents of Salmonella typhimurium ensuring resistance to the drug. Int. J. Antimicrob. Agents 2000, 14, 225-229.
-
(2000)
Int. J. Antimicrob. Agents
, vol.14
, pp. 225-229
-
-
Amaral, L.1
Kristiansen, J.E.2
Thomsen, V.F.3
Markowich, B.4
-
18
-
-
0033033874
-
Potentiality of tricyclic compound thioridazine as an effective antibacterial and antiplasmid agent
-
Radhakrishnan, V.; Ganguly, K.; Ganguly, M.; Dastidar, S. G.; Chakrabarty, A. N. Potentiality of tricyclic compound thioridazine as an effective antibacterial and antiplasmid agent. Indian J. Exp. Biol. 1999, 37, 671-675.
-
(1999)
Indian J. Exp. Biol.
, vol.37
, pp. 671-675
-
-
Radhakrishnan, V.1
Ganguly, K.2
Ganguly, M.3
Dastidar, S.G.4
Chakrabarty, A.N.5
-
19
-
-
0028790130
-
Effects of phenothiazine neuroleptic drugs on the microtubular-membrane complex in bloodstream forms of Trypanosoma brucei
-
Page, A. M.; Lagnado, J. R. Effects of phenothiazine neuroleptic drugs on the microtubular-membrane complex in bloodstream forms of Trypanosoma brucei. Parasitology 1995, 111, 493-504.
-
(1995)
Parasitology
, vol.111
, pp. 493-504
-
-
Page, A.M.1
Lagnado, J.R.2
-
20
-
-
0027017181
-
In vitro antimicrobial activity of 18 phenothiazine derivatives: Structure-activity relationship
-
Bourlioux, P.; Moreaux, J. M.; Su, W. J.; Boureau, H. In vitro antimicrobial activity of 18 phenothiazine derivatives: Structure-activity relationship. APMIS Suppl. 1992, 30, 40-43.
-
(1992)
APMIS
, vol.30
, Issue.SUPPL.
, pp. 40-43
-
-
Bourlioux, P.1
Moreaux, J.M.2
Su, W.J.3
Boureau, H.4
-
21
-
-
85020656381
-
-
Eds., John Wiley & Sons, Inc.: NY, NY, USA
-
Mitruka, B. M., Rawnsle, H. M., Vadehra, D. V., Eds. Animal of Medical Research; John Wiley & Sons, Inc.: NY, NY, USA, 1976; Volume 301, pp. 145-150.
-
(1976)
Animal of Medical Research
, vol.301
, pp. 145-150
-
-
Mitruka, B.M.1
Rawnsle, H.M.2
Vadehra, D.V.3
-
22
-
-
0035996896
-
Intracellular activity of clinical concentrations of phenothiazines including thioridazine against phagocytosed Staphylococcus aureus
-
Ordway, D.; Viveiros, M.; Leandro, C.; Arroz, M. J.; Amaral, L. Intracellular activity of clinical concentrations of phenothiazines including thioridazine against phagocytosed Staphylococcus aureus. Int. J. Antimicrob. Agents 2001, 20, 34-43.
-
(2001)
Int. J. Antimicrob. Agents
, vol.20
, pp. 34-43
-
-
Ordway, D.1
Viveiros, M.2
Leandro, C.3
Arroz, M.J.4
Amaral, L.5
-
23
-
-
39149121434
-
Potential role of non-antibiotics (helper compounds) in the treatment of multi-drug resistant Gram negative infections: Mechanisms for their direct and indirect activities
-
Martins, M.; Dastidar, S. G.; Fanning, S.; Kristiansen, J. E.; Molnar, J.; Pagès, J. M.; Schelz, Z.; Spengler, G.; Viveiros, M.; Amaral, L. Potential role of non-antibiotics (helper compounds) in the treatment of multi-drug resistant Gram negative infections: Mechanisms for their direct and indirect activities. Int. J. Antimicrob. Agents 2008, 31, 198-208.
-
(2008)
Int. J. Antimicrob. Agents
, vol.31
, pp. 198-208
-
-
Martins, M.1
Dastidar, S.G.2
Fanning, S.3
Kristiansen, J.E.4
Molnar, J.5
Pagès, J.M.6
Schelz, Z.7
Spengler, G.8
Viveiros, M.9
Amaral, L.10
-
24
-
-
79959961390
-
New Patentable use of an old neuroleptic compound thioridazine to combat against tuberculosis: Gene regulation perspective
-
Dutta, N. K.; Mazumdar, K.; Dastidar, S. G.; Amaral, L. New Patentable use of an old neuroleptic compound thioridazine to combat against tuberculosis: Gene regulation perspective. Recent Pat. Anti-Infect. Drug Discov. 2011, 6, 128-138.
-
(2011)
Recent Pat. Anti-Infect. Drug Discov.
, vol.6
, pp. 128-138
-
-
Dutta, N.K.1
Mazumdar, K.2
Dastidar, S.G.3
Amaral, L.4
-
25
-
-
82955237533
-
Genetic Response of Salmonella enterica serovar Typhimurium to Thioridazine rendering the organism resistant to the agent
-
Spengler, G.; Rodrigues, L.; Martins, M.; McCusker, M.; Cerca, P.; Machado, L.; Costa, S. S.; Ntokoue, E.; Couto, I.; Viveiros, M.; et al. Genetic Response of Salmonella enterica serovar Typhimurium to Thioridazine rendering the organism resistant to the agent. Int. J. Antimicrob. Agents 2012, 39, 16-21.
-
(2012)
Int. J. Antimicrob. Agents
, vol.39
, pp. 16-21
-
-
Spengler, G.1
Rodrigues, L.2
Martins, M.3
McCusker, M.4
Cerca, P.5
Machado, L.6
Costa, S.S.7
Ntokoue, E.8
Couto, I.9
Viveiros, M.10
-
26
-
-
0035721056
-
Antimicrobial activity of prenylflavanones
-
Dastidar, S. G.; Mahapatra, S. K.; Ganguly, K.; Chakrabarty, A. N. Antimicrobial activity of prenylflavanones. In Vivo 2001, 15, 519-524.
-
(2001)
In Vivo
, vol.15
, pp. 519-524
-
-
Dastidar, S.G.1
Mahapatra, S.K.2
Ganguly, K.3
Chakrabarty, A.N.4
-
27
-
-
0347090623
-
Studies on the antibacterial potentiality of isoflavones
-
Dastidar, S. G.; Manna, A.; Kumar, K. A.; Mazumdar, K.; Dutta, N. K.; Chakrabarty, A. N.; Motohashi, N.; Shirataki, Y. Studies on the antibacterial potentiality of isoflavones. Int. J. Antimicrob. Agents 2004, 23, 99-102.
-
(2004)
Int. J. Antimicrob. Agents
, vol.23
, pp. 99-102
-
-
Dastidar, S.G.1
Manna, A.2
Kumar, K.A.3
Mazumdar, K.4
Dutta, N.K.5
Chakrabarty, A.N.6
Motohashi, N.7
Shirataki, Y.8
-
28
-
-
20444477225
-
Effect of Mesua ferrea Linn. flower extract on Salmonella
-
Mazumder, R.; Dastidar, S. G.; Basu, S. P.; Mazumder, A. Effect of Mesua ferrea Linn. flower extract on Salmonella. Indian J. Exp. Biol. 2005, 43, 566-568.
-
(2005)
Indian J. Exp. Biol.
, vol.43
, pp. 566-568
-
-
Mazumder, R.1
Dastidar, S.G.2
Basu, S.P.3
Mazumder, A.4
-
29
-
-
78650262885
-
Inhibition of efflux pumps of methicillin-resistant Staphylococcus aureus and Enterococcus faecalis resistant strains by triterpenoids from Momordica balsamina
-
Ramalhete, C.; Spengler, G.; Mulhovo, S.; Costa, S.; Couto, I.; Viveiros, M.; Ferreira, M. J. U.; Amaral, L. Inhibition of efflux pumps of methicillin-resistant Staphylococcus aureus and Enterococcus faecalis resistant strains by triterpenoids from Momordica balsamina. Int. J. Antimicrob. Agents 2011, 77, 70-74.
-
(2011)
Int. J. Antimicrob. Agents
, vol.77
, pp. 70-74
-
-
Ramalhete, C.1
Spengler, G.2
Mulhovo, S.3
Costa, S.4
Couto, I.5
Viveiros, M.6
Ferreira, M.J.U.7
Amaral, L.8
-
30
-
-
79953836705
-
Antibacterial properties of compounds isolated from Carpobrotus edulis
-
Martins, A.; Vasas, A.; Viveiros, M.; Molnar, J.; Hohmann, J.; Amaral, L. Antibacterial properties of compounds isolated from Carpobrotus edulis. Int. J. Antimicrob. Agents 2011, 37, 438-444.
-
(2011)
Int. J. Antimicrob. Agents
, vol.37
, pp. 438-444
-
-
Martins, A.1
Vasas, A.2
Viveiros, M.3
Molnar, J.4
Hohmann, J.5
Amaral, L.6
-
31
-
-
85020686886
-
Efflux modulators from Momordica balsamina L. in multidrug resistant bacterial strains
-
Ramalhete, C.; Spengler, G.; Serly, J.; Amaral, L.; Molnar, J.; Mulhovo, S.; Ferreira, M. J. U. Efflux modulators from Momordica balsamina L. in multidrug resistant bacterial strains. Planta Med. 2009, 75, 896-896.
-
(2009)
Planta Med.
, vol.75
, pp. 896
-
-
Ramalhete, C.1
Spengler, G.2
Serly, J.3
Amaral, L.4
Molnar, J.5
Mulhovo, S.6
Ferreira, M.J.U.7
-
32
-
-
34447558018
-
Antibacterial activity of ergosterol peroxide against Mycobacterium tuberculosis: Dependence upon system and medium employed
-
Duarte, N.; Ferreira, M. J.; Martins, M.; Viveiros, M.; Amaral, L. Antibacterial activity of ergosterol peroxide against Mycobacterium tuberculosis: Dependence upon system and medium employed. Phytother. Res. 2007, 21, 601-604.
-
(2007)
Phytother. Res.
, vol.21
, pp. 601-604
-
-
Duarte, N.1
Ferreira, M.J.2
Martins, M.3
Viveiros, M.4
Amaral, L.5
-
33
-
-
66149148982
-
Helichrysum italicum essential oil contains compounds that restore chloramphenicol activity on multi-drug resistant isolates from Gram-negative species
-
Lorenzi, V.; Muselli, A.; Bernardini, A. F.; Berti, L.; Pagès, J. M.; Amaral, L.; Bolla, J. M. Helichrysum italicum essential oil contains compounds that restore chloramphenicol activity on multi-drug resistant isolates from Gram-negative species. Antimicrob. Agents Chemother. 2008, 53, 2209-2211.
-
(2008)
Antimicrob. Agents Chemother.
, vol.53
, pp. 2209-2211
-
-
Lorenzi, V.1
Muselli, A.2
Bernardini, A.F.3
Berti, L.4
Pagès, J.M.5
Amaral, L.6
Bolla, J.M.7
-
35
-
-
79958257266
-
Recent progress in biological activities of synthesized phenothiazines
-
Pluta, K.; Morak-Młodawska, B.; Jeleń, M. Recent progress in biological activities of synthesized phenothiazines. Eur. J. Med. Chem. 2011, 46, 3179-3189.
-
(2011)
Eur. J. Med. Chem.
, vol.46
, pp. 3179-3189
-
-
Pluta, K.1
Morak-Młodawska, B.2
Jeleń, M.3
-
36
-
-
34447547640
-
Reversal of resistance in microorganisms by help of non-antibiotics
-
Kristiansen, J. E.; Hendricks, O.; Delvin, T.; Butterworth, T. S.; Aagaard, L.; Christensen, J. B.; Flores, V. C.; Keyzer, H. Reversal of resistance in microorganisms by help of non-antibiotics. J. Antimicrob. Chemother. 2007, 59, 1271-1279.
-
(2007)
J. Antimicrob. Chemother.
, vol.59
, pp. 1271-1279
-
-
Kristiansen, J.E.1
Hendricks, O.2
Delvin, T.3
Butterworth, T.S.4
Aagaard, L.5
Christensen, J.B.6
Flores, V.C.7
Keyzer, H.8
-
37
-
-
22944439377
-
Phenothiazinium based photosensitisers-photodynamic agents with a multiplicity of cellular targets and clinical applications
-
Harris, F.; Chatfield, L. K.; Phoenix, D. A. Phenothiazinium based photosensitisers-photodynamic agents with a multiplicity of cellular targets and clinical applications. Curr. Drug Targets 2005, 6, 615-627.
-
(2005)
Curr. Drug Targets
, vol.6
, pp. 615-627
-
-
Harris, F.1
Chatfield, L.K.2
Phoenix, D.A.3
-
38
-
-
0036294844
-
Fluorescent and photoactivable probes in depth-dependent analysis of membranes
-
Lala, A. K. Fluorescent and photoactivable probes in depth-dependent analysis of membranes. Chem. Phys. Lipids 2002, 116, 177-188.
-
(2002)
Chem. Phys. Lipids
, vol.116
, pp. 177-188
-
-
Lala, A.K.1
-
39
-
-
33748479692
-
Interactions of phenothiazines with lipid bilayer and their role in multidrug resistance reversal
-
Michalak, K.; Wesolowska, O.; Motohashi, N.; Molnar, J.; Hendrich, A. B. Interactions of phenothiazines with lipid bilayer and their role in multidrug resistance reversal. Curr. Drug Targets 2006, 7, 1095-1105.
-
(2006)
Curr. Drug Targets
, vol.7
, pp. 1095-1105
-
-
Michalak, K.1
Wesolowska, O.2
Motohashi, N.3
Molnar, J.4
Hendrich, A.B.5
-
40
-
-
0019470522
-
Interaction of chlorpromazine with tea and coffee
-
Cheeseman, H. J.; Neal, M. J. Interaction of chlorpromazine with tea and coffee. Br. J. Clin. Pharmacol. 1981, 12, 165-169.
-
(1981)
Br. J. Clin. Pharmacol.
, vol.12
, pp. 165-169
-
-
Cheeseman, H.J.1
Neal, M.J.2
-
41
-
-
0019231651
-
Pharmacological regulation of calmodulin
-
Weiss, B.; Prozialeck, W.; Cimino, M.; Barnette, M. S.; Wallace, T. L. Pharmacological regulation of calmodulin. Ann. NY Acad. Sci. 1980, 356, 319-345.
-
(1980)
Ann. NY Acad. Sci.
, vol.356
, pp. 319-345
-
-
Weiss, B.1
Prozialeck, W.2
Cimino, M.3
Barnette, M.S.4
Wallace, T.L.5
-
42
-
-
0021995178
-
Antispasticity drugs: Mechanisms of action
-
Davidoff, R. A. Antispasticity drugs: Mechanisms of action. Ann. Neurol. 1985, 17, 107-116.
-
(1985)
Ann. Neurol.
, vol.17
, pp. 107-116
-
-
Davidoff, R.A.1
-
43
-
-
84865693407
-
Inhibitors of bacterial efflux pumps that also inhibit efflux pumps of cancer cells
-
Amaral, L.; Spengler, G.; Martins, A.; Armada, A.; Handzlik, J.; Kiec-Kononowicz, K.; Molnar, J. Inhibitors of bacterial efflux pumps that also inhibit efflux pumps of cancer cells. Anticancer Res. 2012, 32, 2947-2957.
-
(2012)
Anticancer Res.
, vol.32
, pp. 2947-2957
-
-
Amaral, L.1
Spengler, G.2
Martins, A.3
Armada, A.4
Handzlik, J.5
Kiec-Kononowicz, K.6
Molnar, J.7
-
44
-
-
52449130017
-
Clinical impact of the over-expression of efflux pump in nonfermentative Gram-negative bacilli, development of efflux pump inhibitors
-
Vila, J.; Martínez, J. L. Clinical impact of the over-expression of efflux pump in nonfermentative Gram-negative bacilli, development of efflux pump inhibitors. Curr. Drug Targets 2008, 9, 797-807.
-
(2008)
Curr. Drug Targets
, vol.9
, pp. 797-807
-
-
Vila, J.1
Martínez, J.L.2
-
45
-
-
64649103209
-
Mechanisms of drug efflux and strategies to combat them: Challenging the efflux pump of Gram-negative bacteria
-
Pagès, J. M.; Amaral, L. Mechanisms of drug efflux and strategies to combat them: challenging the efflux pump of Gram-negative bacteria. Biochim. Biophys. Acta 2009, 1794, 826-833.
-
(2009)
Biochim. Biophys. Acta
, vol.1794
, pp. 826-833
-
-
Pagès, J.M.1
Amaral, L.2
-
46
-
-
79957550202
-
Efflux pumps of gram-negative bacteria: Genetic responses to stress and the modulation of their activity by pH, inhibitors, and phenothiazines
-
Amaral, L.; Fanning, S.; Pagès, J. M. Efflux pumps of gram-negative bacteria: Genetic responses to stress and the modulation of their activity by pH, inhibitors, and phenothiazines. Adv. Enzymol. Relat. Areas Mol. Biol. 2011, 77, 61-108.
-
(2011)
Adv. Enzymol. Relat. Areas Mol. Biol.
, vol.77
, pp. 61-108
-
-
Amaral, L.1
Fanning, S.2
Pagès, J.M.3
-
47
-
-
84855160972
-
Thioridazine induces apoptosis of multidrug-resistant mouse lymphoma cells transfected with the human ABCB1 andinhibits the expression of P-glycoprotein
-
Spengler, G.; Molnar, J.; Viveiros, M.; Amaral, L. Thioridazine induces apoptosis of multidrug-resistant mouse lymphoma cells transfected with the human ABCB1 andinhibits the expression of P-glycoprotein. Anticancer Res. 2011, 31, 4201-4205.
-
(2011)
Anticancer Res.
, vol.31
, pp. 4201-4205
-
-
Spengler, G.1
Molnar, J.2
Viveiros, M.3
Amaral, L.4
-
48
-
-
80054745363
-
Modulation of multidrug efflux pump activity by new hydantoin derivatives on colon adenocarcinoma cells without inducing apoptosis
-
Spengler, G.; Handzlik, J.; Ocsovszki, I.; Viveiros, M.; Kiec-Kononowicz, K.; Molnar, J.; Amaral, L. Modulation of multidrug efflux pump activity by new hydantoin derivatives on colon adenocarcinoma cells without inducing apoptosis. Anticancer Res. 2011, 31, 3285-3288.
-
(2011)
Anticancer Res.
, vol.31
, pp. 3285-3288
-
-
Spengler, G.1
Handzlik, J.2
Ocsovszki, I.3
Viveiros, M.4
Kiec-Kononowicz, K.5
Molnar, J.6
Amaral, L.7
-
49
-
-
0036719989
-
Isoniazid-induced transient high-level resistance in Mycobacterium tuberculosis
-
Viveiros, M.; Portugal, I.; Bettencourt, R.; Victor, T. C.; Jordaan, A. M.; Leandro, C.; Ordway, D.; Amaral, L. Isoniazid-induced transient high-level resistance in Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 2002, 46, 2804-2810.
-
(2002)
Antimicrob. Agents Chemother.
, vol.46
, pp. 2804-2810
-
-
Viveiros, M.1
Portugal, I.2
Bettencourt, R.3
Victor, T.C.4
Jordaan, A.M.5
Leandro, C.6
Ordway, D.7
Amaral, L.8
-
50
-
-
23044454231
-
Inducement and reversal of tetracycline resistance in Escherichia coli K-12 and the expression of proton gradient dependent multidrug efflux pump genes
-
Viveiros, M.; Jesus, A.; Brito, M.; Leandro, C.; Martins, M.; Ordway, D.; Molnar, A. M.; Molnar, J.; Amaral, L. Inducement and reversal of tetracycline resistance in Escherichia coli K-12 and the expression of proton gradient dependent multidrug efflux pump genes. Antimicrob. Agents Chemother. 2005, 49, 3578-3582.
-
(2005)
Antimicrob. Agents Chemother.
, vol.49
, pp. 3578-3582
-
-
Viveiros, M.1
Jesus, A.2
Brito, M.3
Leandro, C.4
Martins, M.5
Ordway, D.6
Molnar, A.M.7
Molnar, J.8
Amaral, L.9
-
51
-
-
70350621247
-
AcrAB mediated MDR phenotype is maintained after efflux pump genes and their regulators have restored wild type activities
-
Martins, A.; Spengler, G.; Rodrigues, L.; Viveiros, M.; Ramos, J.; Martins, M.; Couto, I.; Fanning, S.; Pages, J. M.; Bolla, J. M.; et al. AcrAB mediated MDR phenotype is maintained after efflux pump genes and their regulators have restored wild type activities. Int. J. Antimicrob. Agents 2009, 34, 602-604.
-
(2009)
Int. J. Antimicrob. Agents
, vol.34
, pp. 602-604
-
-
Martins, A.1
Spengler, G.2
Rodrigues, L.3
Viveiros, M.4
Ramos, J.5
Martins, M.6
Couto, I.7
Fanning, S.8
Pages, J.M.9
Bolla, J.M.10
-
52
-
-
84962044479
-
Sequential responses of bacteria to noxious agents (antibiotics) leading to accumulation of mutations and permanent resistance
-
doi: 10. 4172/2167-0501. 1000104
-
Martins, A.; Spengler, G.; Molnar, J.; Amaral, L. Sequential responses of bacteria to noxious agents (antibiotics) leading to accumulation of mutations and permanent resistance. Biochem. Pharmacol. 2012, 1, doi: 10. 4172/2167-0501. 1000104.
-
(2012)
Biochem. Pharmacol.
, vol.1
-
-
Martins, A.1
Spengler, G.2
Molnar, J.3
Amaral, L.4
-
53
-
-
0037699291
-
The role of mutators in the emergence of antibiotic-resistant bacteria
-
Chopra, I.; O'Neill, A. J.; Miller, K. The role of mutators in the emergence of antibiotic-resistant bacteria. Drug Resist. Updat. 2003, 6, 137-145.
-
(2003)
Drug Resist. Updat.
, vol.6
, pp. 137-145
-
-
Chopra, I.1
O'Neill, A.J.2
Miller, K.3
-
54
-
-
80054939368
-
Exploring the contribution of efflux on the resistance to fluoroquinolones in clinical isolates of Staphylococcus aureus
-
doi: 10. 1186/1471-2180-11-241
-
Costa, S. S.; Falcão, C.; Viveiros, M.; Machado, D.; Martins, M.; Melo-Cristino, J.; Amaral, L.; Couto, I. Exploring the contribution of efflux on the resistance to fluoroquinolones in clinical isolates of Staphylococcus aureus. BMC Microbiol. 2011, 11, doi: 10. 1186/1471-2180-11-241.
-
(2011)
BMC Microbiol.
, vol.11
-
-
Costa, S.S.1
Falcão, C.2
Viveiros, M.3
Machado, D.4
Martins, M.5
Melo-Cristino, J.6
Amaral, L.7
Couto, I.8
-
55
-
-
78249239176
-
Identification of the plasmid-encoded qacA efflux pump gene in meticillin-resistant Staphylococcus aureus (MRSA) strain HPV107, a representative of the MRSA Iberian clone
-
Costa, S. S.; Ntokou, E.; Martins, A.; Viveiros, M.; Pournaras, S.; Couto, I.; Amaral, L. Identification of the plasmid-encoded qacA efflux pump gene in meticillin-resistant Staphylococcus aureus (MRSA) strain HPV107, a representative of the MRSA Iberian clone. Int. J. Antimicrob. Agents 2010, 36, 557-561.
-
(2010)
Int. J. Antimicrob. Agents
, vol.36
, pp. 557-561
-
-
Costa, S.S.1
Ntokou, E.2
Martins, A.3
Viveiros, M.4
Pournaras, S.5
Couto, I.6
Amaral, L.7
-
56
-
-
63049100884
-
Characterization of intrinsic efflux activity of Enterococcus faecalis ATCC29212 by a semi-automated ethidium bromide method
-
Spengler, G.; Martins, A.; Schelz, Z.; Rodrigues, L.; Aagaard, L.; Martins, M.; Costa, S. S.; Couto, I.; Viveiros, M.; Fanning, S.; et al. Characterization of intrinsic efflux activity of Enterococcus faecalis ATCC29212 by a semi-automated ethidium bromide method. In Vivo 2009, 23, 81-87.
-
(2009)
In Vivo
, vol.23
, pp. 81-87
-
-
Spengler, G.1
Martins, A.2
Schelz, Z.3
Rodrigues, L.4
Aagaard, L.5
Martins, M.6
Costa, S.S.7
Couto, I.8
Viveiros, M.9
Fanning, S.10
-
57
-
-
84868155091
-
Inhibitors of mycobacterial efflux pumps as potential boosters for TB drugs
-
Viveiros, M.; Martins, M.; Rodrigues, L.; Machado, D.; Couto, I.; Ainsa, J.; Amaral, L. Inhibitors of mycobacterial efflux pumps as potential boosters for TB drugs. Expert Rev. Anti-Infect. Ther. 2012, 10, 983-998.
-
(2012)
Expert Rev. Anti-Infect. Ther.
, vol.10
, pp. 983-998
-
-
Viveiros, M.1
Martins, M.2
Rodrigues, L.3
Machado, D.4
Couto, I.5
Ainsa, J.6
Amaral, L.7
-
58
-
-
84859513842
-
Contribution of efflux to the emergence of isoniazid and multidrug resistance in Mycobacterium tuberculosis
-
Machado, D.; Couto, I.; Perdigão, J.; Rodrigues, L.; Portugal, I.; Baptista, P.; Veigas, B.; Amaral, L.; Viveiros, M. Contribution of efflux to the emergence of isoniazid and multidrug resistance in Mycobacterium tuberculosis. PLoS One 2012, 7, e34538.
-
(2012)
PLoS One
, vol.7
-
-
Machado, D.1
Couto, I.2
Perdigão, J.3
Rodrigues, L.4
Portugal, I.5
Baptista, P.6
Veigas, B.7
Amaral, L.8
Viveiros, M.9
-
59
-
-
84859421891
-
Contribution of efflux activity to isoniazid resistance in the Mycobacterium tuberculosis complex
-
Rodrigues, L.; Machado, D.; Couto, I.; Amaral, L.; Viveiros, M. Contribution of efflux activity to isoniazid resistance in the Mycobacterium tuberculosis complex. Infect. Genet. Evol. 2012, 12, 695-700.
-
(2012)
Infect. Genet. Evol.
, vol.12
, pp. 695-700
-
-
Rodrigues, L.1
Machado, D.2
Couto, I.3
Amaral, L.4
Viveiros, M.5
-
60
-
-
79959759805
-
Ethidium bromide efflux by salmonella: Modulation by metabolic energy, pH, ions and phenothiazines
-
Amaral, L.; Cerca, P.; Spengler, G.; Machado, L.; Couto, I.; Viveiros, M.; Fanning, S.; Pagès, J.-M. Ethidium bromide efflux by salmonella: Modulation by metabolic energy, pH, ions and phenothiazines. Int. J. Antimicrob. Agents 2011, 38, 140-145.
-
(2011)
Int. J. Antimicrob. Agents
, vol.38
, pp. 140-145
-
-
Amaral, L.1
Cerca, P.2
Spengler, G.3
Machado, L.4
Couto, I.5
Viveiros, M.6
Fanning, S.7
Pagès, J.-M.8
-
61
-
-
17144387894
-
Proton transfer dynamics at membrane/water interface and mechanism of biological energy conversion
-
Mulkidjanian, A. Y.; Cherepanov, D. A.; Heberle, J.; Junge, W. Proton transfer dynamics at membrane/water interface and mechanism of biological energy conversion. Biochemistry (Moscow) 2005, 70, 251-256.
-
(2005)
Biochemistry (Moscow)
, vol.70
, pp. 251-256
-
-
Mulkidjanian, A.Y.1
Cherepanov, D.A.2
Heberle, J.3
Junge, W.4
-
62
-
-
33749128697
-
Protons @ interfaces: Implications for biological energy conversion
-
Mulkidjanian, A. Y.; Heberle, J.; Cherepanov, D. A. Protons @ interfaces: Implications for biological energy conversion. Biochim. Biophys. Acta 2006, 1757, 913-930.
-
(2006)
Biochim. Biophys. Acta
, vol.1757
, pp. 913-930
-
-
Mulkidjanian, A.Y.1
Heberle, J.2
Cherepanov, D.A.3
-
63
-
-
84857823876
-
Inhibition of quorum sensing and efflux pump system by trifluoromethyl ketone proton pump inhibitors
-
Varga, Z. G.; Armada, A.; Cerca, P.; Amaral, L.; Mior Ahmad Subki, M. A.; Savka, M. A.; Szegedi, E.; Kawase, M.; Motohashi, N.; Molnár, J. Inhibition of quorum sensing and efflux pump system by trifluoromethyl ketone proton pump inhibitors. In Vivo 2012, 26, 277-285.
-
(2012)
In Vivo
, vol.26
, pp. 277-285
-
-
Varga, Z.G.1
Armada, A.2
Cerca, P.3
Amaral, L.4
Mior Ahmad Subki, M.A.5
Savka, M.A.6
Szegedi, E.7
Kawase, M.8
Motohashi, N.9
Molnár, J.10
-
64
-
-
0027793370
-
Mechanisms of antimotility action of tricyclic compounds in Proteus vulgaris
-
Ren, J. K.; Petöfi, S.; Molnár, J. Mechanisms of antimotility action of tricyclic compounds in Proteus vulgaris. Acta Microbiol. Hung. 1993, 40, 369-377.
-
(1993)
Acta Microbiol. Hung.
, vol.40
, pp. 369-377
-
-
Ren, J.K.1
Petöfi, S.2
Molnár, J.3
-
65
-
-
0027052626
-
Chlorpromazine: A drug potentially useful for treating mycobacteria infections
-
Crowle, A. J.; Douvas, G. S.; May, M. H. Chlorpromazine: A drug potentially useful for treating mycobacteria infections. Chemotherapy 1992, 38, 410-419.
-
(1992)
Chemotherapy
, vol.38
, pp. 410-419
-
-
Crowle, A.J.1
Douvas, G.S.2
May, M.H.3
-
66
-
-
0030462751
-
Inhibition of the respiration of multi-drug resistant clinical isolates of Mycobacterium tuberculosis by Thioridazine: Potential use for the initial therapy of freshly diagnosed tuberculosis
-
Amaral, L.; Kristiansen, J. E.; Abebe, L. S.; Millet, W. Inhibition of the respiration of multi-drug resistant clinical isolates of Mycobacterium tuberculosis by Thioridazine: Potential use for the initial therapy of freshly diagnosed tuberculosis. J. Antimicrob. Chemother. 1996, 38, 1049-1053.
-
(1996)
J. Antimicrob. Chemother.
, vol.38
, pp. 1049-1053
-
-
Amaral, L.1
Kristiansen, J.E.2
Abebe, L.S.3
Millet, W.4
-
67
-
-
0037416986
-
Clinical concentrations of Thioridazine kill intracellular Multi-drug resistant Mycobacterium tuberculosis
-
Ordway, D.; Viveiros, M.; Leandro, C.; Amaral, L. Clinical concentrations of Thioridazine kill intracellular Multi-drug resistant Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 2003, 47, 917-922.
-
(2003)
Antimicrob. Agents Chemother.
, vol.47
, pp. 917-922
-
-
Ordway, D.1
Viveiros, M.2
Leandro, C.3
Amaral, L.4
-
68
-
-
62949134547
-
Sila Compound 421, an Inhibitor of efflux pumps of cancer cells, enhances the killing of intracellular XDRTB
-
Martins, M.; Viveiros, M.; Amaral, L. Sila Compound 421, an Inhibitor of efflux pumps of cancer cells, enhances the killing of intracellular XDRTB. Int. J. Antimicrob. Agents 2008, 33, 479-482.
-
(2008)
Int. J. Antimicrob. Agents
, vol.33
, pp. 479-482
-
-
Martins, M.1
Viveiros, M.2
Amaral, L.3
-
69
-
-
35648948351
-
The curative activity of thioridazine on mice infected with Mycobacterium tuberculosis
-
Martins, M.; Viveiros, M.; Amaral, L. The curative activity of thioridazine on mice infected with Mycobacterium tuberculosis. In Vivo 2007, 21, 771-776.
-
(2007)
In Vivo
, vol.21
, pp. 771-776
-
-
Martins, M.1
Viveiros, M.2
Amaral, L.3
-
70
-
-
77958612298
-
Thioridazine shows promising activity in a murine model of multi-drug resistant tuberculosis
-
van Soolingen, D.; Pando, R. H.; Orozco, H.; Aguilar, D.; Magis, C.; van Ingen, J.; Amaral, L.; Boeree, M. Thioridazine shows promising activity in a murine model of multi-drug resistant tuberculosis. PloS One 2010, 5, e12640.
-
(2010)
PloS One
, vol.5
-
-
van Soolingen, D.1
Pando, R.H.2
Orozco, H.3
Aguilar, D.4
Magis, C.5
van Ingen, J.6
Amaral, L.7
Boeree, M.8
-
71
-
-
84855829764
-
Successful alternative treatment of extensively drug-resistant tuberculosis in Argentina with a combination of linezolid, moxifloxacin and thioridazine
-
Abbate, E.; Vescovo, M.; Natiello, M.; Cufré, M.; García, A.; Gonzalez Montaner, P.; Ambroggi, M.; Ritacco, V.; van Soolingen, D. Successful alternative treatment of extensively drug-resistant tuberculosis in Argentina with a combination of linezolid, moxifloxacin and thioridazine. J. Antimicrob. Chemother. 2012, 67, 473-477.
-
(2012)
J. Antimicrob. Chemother.
, vol.67
, pp. 473-477
-
-
Abbate, E.1
Vescovo, M.2
Natiello, M.3
Cufré, M.4
García, A.5
Gonzalez Montaner, P.6
Ambroggi, M.7
Ritacco, V.8
van Soolingen, D.9
-
72
-
-
84865699664
-
Totally Drug Resistant Tuberculosis can be Treated with Thioridazine in Combination with Antibiotics to which the Patient was Initially Resistant
-
doi: 10. 4172/bcpc. 1000e102
-
Amaral, L. Totally Drug Resistant Tuberculosis can be Treated with Thioridazine in Combination with Antibiotics to which the Patient was Initially Resistant. Biochem. Pharmacol. 2012, doi: 10. 4172/bcpc. 1000e102.
-
(2012)
Biochem. Pharmacol.
-
-
Amaral, L.1
-
73
-
-
84859428822
-
Why thioridazine in combination with antibiotics cures extensively drug-resistant Mycobacterium tuberculosis infections
-
Amaral, L.; Viveiros, M. Why thioridazine in combination with antibiotics cures extensively drug-resistant Mycobacterium tuberculosis infections. Int. J. Antimicrob. Agents 2012, 39, 376-380.
-
(2012)
Int. J. Antimicrob. Agents
, vol.39
, pp. 376-380
-
-
Amaral, L.1
Viveiros, M.2
-
74
-
-
84857879092
-
Potential therapy of multidrug-resistant and extremely drug-resistant tuberculosis with thioridazine
-
Amaral, L.; Molnar, J. Potential therapy of multidrug-resistant and extremely drug-resistant tuberculosis with thioridazine. In Vivo 2012, 26, 231-236.
-
(2012)
In Vivo
, vol.26
, pp. 231-236
-
-
Amaral, L.1
Molnar, J.2
-
75
-
-
79959935423
-
Safety and efficacy of thioridazine as salvagetherapy in Indian patients with XDR-TB
-
Udwadia, Z. F.; Sen, T.; Pinto, L. M. Safety and efficacy of thioridazine as salvagetherapy in Indian patients with XDR-TB. Recent Pat. Antiinfect. Drug Discov. 2011, 6, 88-91.
-
(2011)
Recent Pat. Antiinfect. Drug Discov.
, vol.6
, pp. 88-91
-
-
Udwadia, Z.F.1
Sen, T.2
Pinto, L.M.3
-
76
-
-
84870330683
-
The added effect of Thioridazine in treatment of resistant TB
-
Amaral, L.; Udwadia, Z.; Abbate, E.; van Soolingen, D. The added effect of Thioridazine in treatment of resistant TB. Int. J. Tuberc. Lung Dis. 2012, 16, 1706-1708.
-
(2012)
Int. J. Tuberc. Lung Dis.
, vol.16
, pp. 1706-1708
-
-
Amaral, L.1
Udwadia, Z.2
Abbate, E.3
van Soolingen, D.4
-
77
-
-
33646849578
-
Synergistic interaction between proton pump inhibitors and resistance modifiers: Promoting effects of antibiotics and plasmid curing
-
Wolfart, K.; Spengler, G.; Kawase, M.; Motohashi, N.; Molnár, J.; Viveiros, M.; Amaral, L. Synergistic interaction between proton pump inhibitors and resistance modifiers: Promoting effects of antibiotics and plasmid curing. In Vivo 2006, 20, 367-372.
-
(2006)
In Vivo
, vol.20
, pp. 367-372
-
-
Wolfart, K.1
Spengler, G.2
Kawase, M.3
Motohashi, N.4
Molnár, J.5
Viveiros, M.6
Amaral, L.7
-
78
-
-
0042334479
-
Enhancement of plasmid curing by 9-aminoacridine and two phenothiazines in the presence of proton pump inhibitor 1-(2-benzoxazolyl)-3, 3, 3-trifluoro-2-propanone
-
Spengler, G.; Miczák, A.; Hajdú, E.; Kawase, M.; Amaral, L.; Molnár, J. Enhancement of plasmid curing by 9-aminoacridine and two phenothiazines in the presence of proton pump inhibitor 1-(2-benzoxazolyl)-3, 3, 3-trifluoro-2-propanone. Int. J. Antimicrob. Agents 2003, 22, 223-227.
-
(2003)
Int. J. Antimicrob. Agents
, vol.22
, pp. 223-227
-
-
Spengler, G.1
Miczák, A.2
Hajdú, E.3
Kawase, M.4
Amaral, L.5
Molnár, J.6
-
79
-
-
0033033874
-
Potentiality of tricyclic compound thioridazine as an effective antibacterial and antiplasmid agent
-
Radhakrishnan, V.; Ganguly, K.; Ganguly, M.; Dastidar, S. G.; Chakrabarty, A. N. Potentiality of tricyclic compound thioridazine as an effective antibacterial and antiplasmid agent. Indian J. Exp. Biol. 1999, 37, 671-675.
-
(1999)
Indian J. Exp. Biol.
, vol.37
, pp. 671-675
-
-
Radhakrishnan, V.1
Ganguly, K.2
Ganguly, M.3
Dastidar, S.G.4
Chakrabarty, A.N.5
-
80
-
-
0030624055
-
Effect of promethazine hydrochloride (pipolphen) on the stability of R plasmid resistance in Escherichia coli (in Russian)
-
Evdokimova, O. V.; Smirnov, I. V.; Artem'eva, N. A.; Rozhkova, E. A. Effect of promethazine hydrochloride (pipolphen) on the stability of R plasmid resistance in Escherichia coli (in Russian). Antibiot Khimioter 1997, 42, 8-11.
-
(1997)
Antibiot Khimioter
, vol.42
, pp. 8-11
-
-
Evdokimova, O.V.1
Smirnov, I.V.2
Artem'eva, N.A.3
Rozhkova, E.A.4
-
81
-
-
0021321945
-
Inhibition of bacterial plasmid replication by stereoselective binding by tricyclic psychopharmacons
-
Molnár, J.; Gálfi, M.; Lózsa, A.; Nakamura, M. J. Inhibition of bacterial plasmid replication by stereoselective binding by tricyclic psychopharmacons. Res. Commun. Chem. Pathol. Pharmacol. 1984, 43, 235-249.
-
(1984)
Res. Commun. Chem. Pathol. Pharmacol.
, vol.43
, pp. 235-249
-
-
Molnár, J.1
Gálfi, M.2
Lózsa, A.3
Nakamura, M.J.4
|