Guanylated polymethacrylates: A class of potent antimicrobial polymers with low hemolytic activity

Biomacromolecules

Volumn 14, Issue 11, 2013, Pages 4021-4031

  Locock, Katherine E S ^a   Michl, Thomas D ^b   Valentin, Jules D P ^b   Vasilev, Krasimir ^b   Hayball, John D ^b   Qu, Yue ^c   Traven, Ana ^c   Griesser, Hans J ^b   Meagher, Laurence ^a   Haeussler, Matthias ^a  

^a CSIRO   (Australia)

^b UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^c MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-MICROBIAL ACTIVITY; ANTIMICROBIAL PEPTIDE; ANTIMICROBIAL POLYMERS; HYDROPHOBIC CHARACTER; LOW HEMOLYTIC ACTIVITIES; REVERSIBLE ADDITION FRAGMENTATION CHAIN TRANSFER (RAFT); STAPHYLOCOCCUS EPIDERMIDIS; STRUCTURE ACTIVITY RELATIONSHIPS;

ANTIGEN-ANTIBODY REACTIONS; CHAIN LENGTH; COPOLYMERS; HYDROPHOBICITY; MICROORGANISMS; MOLECULAR WEIGHT; POLYDISPERSITY; TOXICITY;

POLYMERS;

AMINE; AMINE FUNCTIONALIZED POLYMER; AMPHOPHILE; ANTIINFECTIVE AGENT; CATION; GUANIDINE DERIVATIVE; GUANIDINE FUNCTIONALIZED POLYMER; POLYMETHACRYLIC ACID DERIVATIVE; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CONTROLLED STUDY; DRUG SYNTHESIS; HEMAGGLUTINATION; HEMOLYSIS; HUMAN; HUMAN CELL; HYDROPHOBICITY; MAMMAL CELL; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR WEIGHT; PRIORITY JOURNAL; STAPHYLOCOCCUS EPIDERMIDIS; TOXICITY TESTING;

ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; CANDIDA ALBICANS; DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROCYTES; GUANIDINES; HEMOLYSIS; HUMANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; POLYMETHACRYLIC ACIDS; STAPHYLOCOCCUS EPIDERMIDIS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84887596476     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm401128r     Document Type: Article

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