Punicalagin, a polyphenol in pomegranate juice, downregulates p53 and attenuates hypoxia-induced apoptosis in cultured human placental syncytiotrophoblasts

American Journal of Physiology - Endocrinology and Metabolism

Volumn 305, Issue 10, 2013, Pages

  Chen, Baosheng ^a   Longtine, Mark S ^a   Nelson, D Michael ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Hypoxia inducible factor ; Mouse double minute 2 homolog; Placenta

Indexed keywords

CASPASE 3; CASPASE 9; HYPOXIA INDUCIBLE FACTOR 1ALPHA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; OXYGEN; POLYPHENOL; PROTEIN BCL 2; PROTEIN MDM2; PROTEIN P21; PROTEIN P53; PUNICALAGIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HYPOXIA; OXIDATIVE STRESS; POMEGRANATE JUICE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNCYTIOTROPHOBLAST;

HYPOXIA-INDUCIBLE FACTOR Α; MOUSE DOUBLE MINUTE 2 HOMOLOG; PLACENTA;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; BEVERAGES; CELL HYPOXIA; CELLS, CULTURED; DOWN-REGULATION; FEMALE; HUMANS; HYDROLYZABLE TANNINS; MICE; POLYPHENOLS; PREGNANCY; PUNICACEAE; TROPHOBLASTS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84887567833     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00218.2013     Document Type: Article

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