-
1
-
-
84887156187
-
A high angiopoietin-2/angiopoietin-1 ratio is associated with a high risk of septic shock in patients with febrile neutropenia
-
10.1186/cc12848, 23915833
-
Fiusa MML, Costa-Lima C, de Souza GR, Vigorito AC, Aranha FJP, Lorand-Metze I, Annichino-Bizzacchi JM, de Souza CA, De Paula EV. A high angiopoietin-2/angiopoietin-1 ratio is associated with a high risk of septic shock in patients with febrile neutropenia. Crit Care 2013, 17:R169. 10.1186/cc12848, 23915833.
-
(2013)
Crit Care
, vol.17
-
-
Fiusa, M.M.L.1
Costa-Lima, C.2
de Souza, G.R.3
Vigorito, A.C.4
Aranha, F.J.P.5
Lorand-Metze, I.6
Annichino-Bizzacchi, J.M.7
de Souza, C.A.8
De Paula, E.V.9
-
2
-
-
15144358851
-
Angiopoietin-2, a natural antagonist for Tie-2 that disrupts in vivo angiogenesis
-
10.1126/science.277.5322.55, 9204896
-
Maisonpierre PC, Suri C, Jones PF, Bartunkova S, Wiegand SJ, Radziejewski C, Compton D, Mclain J, Aldrich TH, Papadopoulos N, Daly TJ, Davis S, Sato TN, Yancopoulos GD. Angiopoietin-2, a natural antagonist for Tie-2 that disrupts in vivo angiogenesis. Science 1997, 277:55-60. 10.1126/science.277.5322.55, 9204896.
-
(1997)
Science
, vol.277
, pp. 55-60
-
-
Maisonpierre, P.C.1
Suri, C.2
Jones, P.F.3
Bartunkova, S.4
Wiegand, S.J.5
Radziejewski, C.6
Compton, D.7
Mclain, J.8
Aldrich, T.H.9
Papadopoulos, N.10
Daly, T.J.11
Davis, S.12
Sato, T.N.13
Yancopoulos, G.D.14
-
3
-
-
0037143737
-
Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo
-
10.1073/pnas.172161899, 123234, 12163646
-
Lobov IB, Brooks PC, Lang RA. Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo. Proc Natl Acad Sci U S A 2002, 99:11205-11210. 10.1073/pnas.172161899, 123234, 12163646.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 11205-11210
-
-
Lobov, I.B.1
Brooks, P.C.2
Lang, R.A.3
-
4
-
-
0033601357
-
Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1
-
10.1126/science.286.5449.2511, 10617467
-
Thurston G, Suri C, Smith K, McClain J, Sato TN, Yancopoulous GD, McDonald DM. Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1. Science 1999, 286:2511-2514. 10.1126/science.286.5449.2511, 10617467.
-
(1999)
Science
, vol.286
, pp. 2511-2514
-
-
Thurston, G.1
Suri, C.2
Smith, K.3
McClain, J.4
Sato, T.N.5
Yancopoulous, G.D.6
McDonald, D.M.7
-
5
-
-
11444264653
-
Plasma vascular endothelial growth factor in severe sepsis
-
10.1097/01.shk.0000150728.91155.41, 15614129
-
van der Flier M, van Leeuwen HJ, van Kessel KP, Kimpen JL, Hoepelman AI, Geelen SP. Plasma vascular endothelial growth factor in severe sepsis. Shock 2005, 23:35-38. 10.1097/01.shk.0000150728.91155.41, 15614129.
-
(2005)
Shock
, vol.23
, pp. 35-38
-
-
van der Flier, M.1
van Leeuwen, H.J.2
van Kessel, K.P.3
Kimpen, J.L.4
Hoepelman, A.I.5
Geelen, S.P.6
-
6
-
-
80055021582
-
The synthetic Tie2 peptide vasculotide protects against vascular leakage and reduces mortality in murine abdominal sepsis
-
10.1186/cc10523, 3334812, 22040774
-
Kumpers P, Gueler F, David S, Slyke PV, Dumont DJ, Park JK, Bockmeyer CL, Parikh SM, Pavenstadt H, Haller H, Shushakova N. The synthetic Tie2 peptide vasculotide protects against vascular leakage and reduces mortality in murine abdominal sepsis. Crit Care 2011, 15:R261. 10.1186/cc10523, 3334812, 22040774.
-
(2011)
Crit Care
, vol.15
-
-
Kumpers, P.1
Gueler, F.2
David, S.3
Slyke, P.V.4
Dumont, D.J.5
Park, J.K.6
Bockmeyer, C.L.7
Parikh, S.M.8
Pavenstadt, H.9
Haller, H.10
Shushakova, N.11
-
7
-
-
79959546082
-
Acute administration of recombinant Angiopoietin-1 ameliorates multiple-organ dysfunction syndrome and improves survival in murine sepsis
-
10.1016/j.cyto.2011.04.005, 21531574
-
David S, Park JK, Meurs M, Zijlstra JG, Koenecke C, Schrimpf C, Shushakova N, Gueler F, Haller H, Kumpers P. Acute administration of recombinant Angiopoietin-1 ameliorates multiple-organ dysfunction syndrome and improves survival in murine sepsis. Cytokine 2011, 55:251-259. 10.1016/j.cyto.2011.04.005, 21531574.
-
(2011)
Cytokine
, vol.55
, pp. 251-259
-
-
David, S.1
Park, J.K.2
Meurs, M.3
Zijlstra, J.G.4
Koenecke, C.5
Schrimpf, C.6
Shushakova, N.7
Gueler, F.8
Haller, H.9
Kumpers, P.10
-
8
-
-
72949100522
-
COMP-angiopoietin-1 decreases lipopolysaccharide-induced acute kidney injury
-
10.1038/ki.2009.387, 19812542
-
Kim DH, Jung YJ, Lee AS, Lee S, Kang KP, Lee TH, Lee SY, Jang KY, Moon WS, Choi KS, Yoon KH, Sung MJ, Park SK, Kim W. COMP-angiopoietin-1 decreases lipopolysaccharide-induced acute kidney injury. Kidney Int 2009, 76:1180-1191. 10.1038/ki.2009.387, 19812542.
-
(2009)
Kidney Int
, vol.76
, pp. 1180-1191
-
-
Kim, D.H.1
Jung, Y.J.2
Lee, A.S.3
Lee, S.4
Kang, K.P.5
Lee, T.H.6
Lee, S.Y.7
Jang, K.Y.8
Moon, W.S.9
Choi, K.S.10
Yoon, K.H.11
Sung, M.J.12
Park, S.K.13
Kim, W.14
-
9
-
-
84881246880
-
Angiopoietin 2 mediates microvascular and hemodynamic alterations in sepsis
-
Epub ahead of print
-
Ziegler T, Horstkotte J, Schwab C, Pfetsch V, Weinmann K, Dietzel S, Rohwedder I, Hinkel R, Gross L, Lee S, Hu J, Soehnlein O, Franz WM, Sperandio M, Pohl U, Thomas M, Weber C, Augustin HG, Fassler R, Deutsch U, Kupatt C. Angiopoietin 2 mediates microvascular and hemodynamic alterations in sepsis. J Clin Invest 2013, Epub ahead of print.
-
(2013)
J Clin Invest
-
-
Ziegler, T.1
Horstkotte, J.2
Schwab, C.3
Pfetsch, V.4
Weinmann, K.5
Dietzel, S.6
Rohwedder, I.7
Hinkel, R.8
Gross, L.9
Lee, S.10
Hu, J.11
Soehnlein, O.12
Franz, W.M.13
Sperandio, M.14
Pohl, U.15
Thomas, M.16
Weber, C.17
Augustin, H.G.18
Fassler, R.19
Deutsch, U.20
Kupatt, C.21
more..
-
10
-
-
77952432851
-
The role of angiogenic factors predicting clinical outcome in severe bacterial infection in Malawian children
-
10.1186/cc9025, 2911728, 20492647
-
Mankhambo LA, Banda DL, Jeffers G, White SA, Balmer P, Nkhoma S, Phiri H, Molyneux EM, Hart CA, Molyneux ME, Heyderman RS, Carrol ED. The role of angiogenic factors predicting clinical outcome in severe bacterial infection in Malawian children. Crit Care 2010, 14:R91. 10.1186/cc9025, 2911728, 20492647.
-
(2010)
Crit Care
, vol.14
-
-
Mankhambo, L.A.1
Banda, D.L.2
Jeffers, G.3
White, S.A.4
Balmer, P.5
Nkhoma, S.6
Phiri, H.7
Molyneux, E.M.8
Hart, C.A.9
Molyneux, M.E.10
Heyderman, R.S.11
Carrol, E.D.12
-
11
-
-
36248988406
-
Admission angiopoietin levels in children with septic shock
-
2754128, 18092380
-
Guiliano JS, Lahni PM, Harmon K, Wong HR, Dought LA, Carcillo JA, Zingarelli B, Sukhatme VP, Parikh SM, Wheeler DS. Admission angiopoietin levels in children with septic shock. Shock 2007, 28:650-654. 2754128, 18092380.
-
(2007)
Shock
, vol.28
, pp. 650-654
-
-
Guiliano, J.S.1
Lahni, P.M.2
Harmon, K.3
Wong, H.R.4
Dought, L.A.5
Carcillo, J.A.6
Zingarelli, B.7
Sukhatme, V.P.8
Parikh, S.M.9
Wheeler, D.S.10
-
12
-
-
33645355399
-
Excess circulating angiopoietins-2 may contribute to pulmonary vascular leak in sepsis in humans
-
10.1371/journal.pmed.0030046, 1334221, 16417407
-
Parikh SM, Mammoto T, Schultz A, Yuan HT, Christiani D, Karamanchi SA, Sukhatme VP. Excess circulating angiopoietins-2 may contribute to pulmonary vascular leak in sepsis in humans. PLoS Med 2006, 3:e46. 10.1371/journal.pmed.0030046, 1334221, 16417407.
-
(2006)
PLoS Med
, vol.3
-
-
Parikh, S.M.1
Mammoto, T.2
Schultz, A.3
Yuan, H.T.4
Christiani, D.5
Karamanchi, S.A.6
Sukhatme, V.P.7
-
13
-
-
33845940689
-
Angiopoietin-2 is increased in severe sepsis: correlation with inflammatory mediators
-
10.1097/01.CCM.0000251640.77679.D7, 17110873
-
Orfanos SE, Kotanidou A, Glynos C, Athansiou C, Tsigkos S, Dimopoulou I, Sotiropoulou C, Zakynthinos S, Armaganidis A, Papapetropoulos A, Roussos C. Angiopoietin-2 is increased in severe sepsis: correlation with inflammatory mediators. Crit Care Med 2007, 35:199-2006. 10.1097/01.CCM.0000251640.77679.D7, 17110873.
-
(2007)
Crit Care Med
, vol.35
, pp. 199-2006
-
-
Orfanos, S.E.1
Kotanidou, A.2
Glynos, C.3
Athansiou, C.4
Tsigkos, S.5
Dimopoulou, I.6
Sotiropoulou, C.7
Zakynthinos, S.8
Armaganidis, A.9
Papapetropoulos, A.10
Roussos, C.11
-
14
-
-
64849117308
-
Elevated serum angiopoietin-2 levels are associated with increased mortality in sepsis
-
10.1097/SHK.0b013e318188bd06, 18791490
-
Siner JM, Bhandari V, Engle KM, Elias JA, Siegel MD. Elevated serum angiopoietin-2 levels are associated with increased mortality in sepsis. Shock 2009, 31:348-353. 10.1097/SHK.0b013e318188bd06, 18791490.
-
(2009)
Shock
, vol.31
, pp. 348-353
-
-
Siner, J.M.1
Bhandari, V.2
Engle, K.M.3
Elias, J.A.4
Siegel, M.D.5
-
15
-
-
77952692518
-
Imbalances in serum angiopoietins concentrations are early predictors of septic shock development in patients with post chemotherapy febrile neutropenia
-
10.1186/1471-2334-10-143, 2890004, 20509945
-
Alves BE, Montalvao SA, Aranha FJ, Siegl TF, Souza CA, Lorand-Metze I, Annichino-Bizzacchi JM, De Paula EV. Imbalances in serum angiopoietins concentrations are early predictors of septic shock development in patients with post chemotherapy febrile neutropenia. BMC Infect Dis 2010, 10:143. 10.1186/1471-2334-10-143, 2890004, 20509945.
-
(2010)
BMC Infect Dis
, vol.10
, pp. 143
-
-
Alves, B.E.1
Montalvao, S.A.2
Aranha, F.J.3
Siegl, T.F.4
Souza, C.A.5
Lorand-Metze, I.6
Annichino-Bizzacchi, J.M.7
De Paula, E.V.8
-
16
-
-
79953218683
-
Angiopoietin-2 and angiopoietin-1 as clinically informative prognostic biomarkers of morbidity and mortality in severe sepsis
-
10.1097/CCM.0b013e318206d285, 21242795
-
Ricciuto DR, Dos Santos CC, Hawkes M, Toltl LJ, Conroy AL, Rajwans N, Lafferty EI, Cook DJ, Fox-Robichaud A, Kahnamoui K, Kain KC, Liaw PC, Liles WC. Angiopoietin-2 and angiopoietin-1 as clinically informative prognostic biomarkers of morbidity and mortality in severe sepsis. Crit Care Med 2011, 39:702-710. 10.1097/CCM.0b013e318206d285, 21242795.
-
(2011)
Crit Care Med
, vol.39
, pp. 702-710
-
-
Ricciuto, D.R.1
Dos Santos, C.C.2
Hawkes, M.3
Toltl, L.J.4
Conroy, A.L.5
Rajwans, N.6
Lafferty, E.I.7
Cook, D.J.8
Fox-Robichaud, A.9
Kahnamoui, K.10
Kain, K.C.11
Liaw, P.C.12
Liles, W.C.13
-
17
-
-
84868196659
-
Angiopoietin-2 may contribute to multiple organ dysfunction and death in sepsis
-
10.1097/CCM.0b013e31825fdc31, 22890252
-
David S, Mukherjee A, Ghosh CC, Yano M, Khankin EV, Wenger JB, Karumanchi SA, Shapiro NI, Parikh SM. Angiopoietin-2 may contribute to multiple organ dysfunction and death in sepsis. Crit Care Med 2012, 40:3034-3041. 10.1097/CCM.0b013e31825fdc31, 22890252.
-
(2012)
Crit Care Med
, vol.40
, pp. 3034-3041
-
-
David, S.1
Mukherjee, A.2
Ghosh, C.C.3
Yano, M.4
Khankin, E.V.5
Wenger, J.B.6
Karumanchi, S.A.7
Shapiro, N.I.8
Parikh, S.M.9
-
18
-
-
0035829842
-
Early goal-directed therapy in the treatment of severe sepsis and septic shock
-
10.1056/NEJMoa010307, 11794169, Early Goal Directed Therapy Collaborative Group
-
Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, Peterson E, Tomlanovich M. Early Goal Directed Therapy Collaborative Group Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001, 345:1368-1377. 10.1056/NEJMoa010307, 11794169, Early Goal Directed Therapy Collaborative Group.
-
(2001)
N Engl J Med
, vol.345
, pp. 1368-1377
-
-
Rivers, E.1
Nguyen, B.2
Havstad, S.3
Ressler, J.4
Muzzin, A.5
Knoblich, B.6
Peterson, E.7
Tomlanovich, M.8
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