-
1
-
-
13044316551
-
Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand
-
Hsu H, et al. Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand. Proc Natl Acad Sci U S A. 1999;96(7):3540-3545.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, Issue.7
, pp. 3540-3545
-
-
Hsu, H.1
-
2
-
-
0037202907
-
Macrophage colonystimulating factor promotes the survival of osteoclast precursors by up-regulating Bcl-X(L)
-
Woo KM, Kim HM, Ko JS. Macrophage colonystimulating factor promotes the survival of osteoclast precursors by up-regulating Bcl-X(L). Exp Mol Med. 2002;34(5):340-346.
-
(2002)
Exp Mol Med
, vol.34
, Issue.5
, pp. 340-346
-
-
Woo, K.M.1
Kim, H.M.2
Ko, J.S.3
-
3
-
-
0033611467
-
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
-
Kong YY, et al. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature. 1999;397(6717):315-323.
-
(1999)
Nature
, vol.397
, Issue.6717
, pp. 315-323
-
-
Kong, Y.Y.1
-
4
-
-
0033888977
-
Osteoprotegerin ligand modulates murine osteoclast survival in vitro and in vivo
-
Lacey DL, et al. Osteoprotegerin ligand modulates murine osteoclast survival in vitro and in vivo. Am J Pathol. 2000;157(2):435-448.
-
(2000)
Am J Pathol
, vol.157
, Issue.2
, pp. 435-448
-
-
Lacey, D.L.1
-
5
-
-
0033519221
-
The ligand for osteoprotegerin (OPGL) directly activates mature osteoclasts
-
Burgess TL, et al. The ligand for osteoprotegerin (OPGL) directly activates mature osteoclasts. J Cell Biol. 1999;145(3):527-538.
-
(1999)
J Cell Biol
, vol.145
, Issue.3
, pp. 527-538
-
-
Burgess, T.L.1
-
6
-
-
0034835405
-
Regulation of osteoclastogenesis and RANK expression by TGF-β1
-
Yan T, Riggs BL, Boyle WJ, Khosla S. Regulation of osteoclastogenesis and RANK expression by TGF-β1. J Cell Biochem. 2001;83(2):320-325.
-
(2001)
J Cell Biochem
, vol.83
, Issue.2
, pp. 320-325
-
-
Yan, T.1
Riggs, B.L.2
Boyle, W.J.3
Khosla, S.4
-
7
-
-
33646593852
-
Transforming growth factorbeta1 induces Nox4 NAD(P)H oxidase and reactive oxygen species-dependent proliferation in human pulmonary artery smooth muscle cells
-
Sturrock A, et al. Transforming growth factorbeta1 induces Nox4 NAD(P)H oxidase and reactive oxygen species-dependent proliferation in human pulmonary artery smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2006;290(4):L661-L673.
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.290
, Issue.4
-
-
Sturrock, A.1
-
8
-
-
79953881843
-
The E-loop is involved in hydrogen peroxide formation by the NADPH oxidase Nox4
-
Takac I, et al. The E-loop is involved in hydrogen peroxide formation by the NADPH oxidase Nox4. J Biol Chem. 2011;286(15):13304-13313.
-
(2011)
J Biol Chem
, vol.286
, Issue.15
, pp. 13304-13313
-
-
Takac, I.1
-
9
-
-
59449096625
-
Nox4 acts as a switch between differentiation and proliferation in preadipocytes
-
Schroder K, Wandzioch K, Helmcke I, Brandes RP. Nox4 acts as a switch between differentiation and proliferation in preadipocytes. Arterioscler Thromb Vasc Biol. 2009;29(2):239-245.
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, Issue.2
, pp. 239-245
-
-
Schroder, K.1
Wandzioch, K.2
Helmcke, I.3
Brandes, R.P.4
-
10
-
-
0025236484
-
Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo
-
Garrett IR, Boyce BF, Oreffo RO, Bonewald L, Poser J, Mundy GR. Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo. J Clin Invest. 1990;85(3):632-639.
-
(1990)
J Clin Invest
, vol.85
, Issue.3
, pp. 632-639
-
-
Garrett, I.R.1
Boyce, B.F.2
Oreffo, R.O.3
Bonewald, L.4
Poser, J.5
Mundy, G.R.6
-
11
-
-
79955669262
-
Calcium signaling in osteoclasts
-
Hwang SY, Putney JW. Calcium signaling in osteoclasts. Biochim Biophys Acta. 2011;1813(5):979-983.
-
(2011)
Biochim Biophys Acta
, vol.1813
, Issue.5
, pp. 979-983
-
-
Hwang, S.Y.1
Putney, J.W.2
-
12
-
-
22144457305
-
A crucial role for reactive oxygen species in RANKL-induced osteoclast differentiation
-
Lee NK, et al. A crucial role for reactive oxygen species in RANKL-induced osteoclast differentiation. Blood. 2005;106(3):852-859.
-
(2005)
Blood
, vol.106
, Issue.3
, pp. 852-859
-
-
Lee, N.K.1
-
13
-
-
63349098916
-
NADPH oxidase-derived reactive oxygen species are essential for differentiation of a mouse macrophage cell line (RAW264.7) into osteoclasts
-
Sasaki H, et al. NADPH oxidase-derived reactive oxygen species are essential for differentiation of a mouse macrophage cell line (RAW264.7) into osteoclasts. J Med Invest. 2009;56(1-2):33-41.
-
(2009)
J Med Invest
, vol.56
, Issue.1-2
, pp. 33-41
-
-
Sasaki, H.1
-
14
-
-
78149268561
-
First in class, potent, and orally bioavailable NADPH oxidase isoform 4 (Nox4) inhibitors for the treatment of idiopathic pulmonary fibrosis
-
Laleu B, et al. First in class, potent, and orally bioavailable NADPH oxidase isoform 4 (Nox4) inhibitors for the treatment of idiopathic pulmonary fibrosis. J Med Chem. 2010;53(21):7715-7730.
-
(2010)
J Med Chem
, vol.53
, Issue.21
, pp. 7715-7730
-
-
Laleu, B.1
-
15
-
-
33846031926
-
The molecular understanding of osteoclast differentiation
-
Asagiri M, Takayanagi H. The molecular understanding of osteoclast differentiation. Bone. 2007; 40(2):251-264.
-
(2007)
Bone
, vol.40
, Issue.2
, pp. 251-264
-
-
Asagiri, M.1
Takayanagi, H.2
-
16
-
-
1942475329
-
Genetic predisposition for adult lactose intolerance and relation to diet, bone density, and bone fractures
-
Obermayer-Pietsch BM, et al. Genetic predisposition for adult lactose intolerance and relation to diet, bone density, and bone fractures. J Bone Miner Res. 2004;19(1):42-47.
-
(2004)
J Bone Miner Res
, vol.19
, Issue.1
, pp. 42-47
-
-
Obermayer-Pietsch, B.M.1
-
17
-
-
84877157804
-
Steroids and osteoporosis: The quest for mechanisms
-
Manolagas SC. Steroids and osteoporosis: the quest for mechanisms. J Clin Invest. 2013;123(5):1919-1921.
-
(2013)
J Clin Invest
, vol.123
, Issue.5
, pp. 1919-1921
-
-
Manolagas, S.C.1
-
18
-
-
56549089663
-
Oxidative stress, free radicals and bone remodeling
-
Banfi G, Iorio EL, Corsi MM. Oxidative stress, free radicals and bone remodeling. Clin Chem Lab Med. 2008;46(11)1550-1555.
-
(2008)
Clin Chem Lab Med
, vol.46
, Issue.11
, pp. 1550-1555
-
-
Banfi, G.1
Iorio, E.L.2
Corsi, M.M.3
-
19
-
-
79952026736
-
NADPH oxidasemediated redox signaling: Roles in cellular stress response, stress tolerance, and tissue repair
-
Jiang F, Zhang Y, Dusting GJ. NADPH oxidasemediated redox signaling: roles in cellular stress response, stress tolerance, and tissue repair. Pharmacol Rev. 2011;63(1):218-242.
-
(2011)
Pharmacol Rev
, vol.63
, Issue.1
, pp. 218-242
-
-
Jiang, F.1
Zhang, Y.2
Dusting, G.J.3
-
20
-
-
79953083276
-
BAPTA-AM, an intracellular calcium chelator, inhibits RANKL-induced bone marrow macrophages differentiation through MEK/ERK, p38 MAPK and Akt, but not JNK pathways
-
Zhou S, et al. BAPTA-AM, an intracellular calcium chelator, inhibits RANKL-induced bone marrow macrophages differentiation through MEK/ERK, p38 MAPK and Akt, but not JNK pathways. Cytokine. 2010;52(3):210-214.
-
(2010)
Cytokine
, vol.52
, Issue.3
, pp. 210-214
-
-
Zhou, S.1
-
21
-
-
78649443616
-
RANKL-induced TRPV2 expression regulates osteoclastogenesis via calcium oscillations
-
Kajiya H, et al. RANKL-induced TRPV2 expression regulates osteoclastogenesis via calcium oscillations. Cell Calcium. 2010;48(5):260-269.
-
(2010)
Cell Calcium
, vol.48
, Issue.5
, pp. 260-269
-
-
Kajiya, H.1
-
22
-
-
77955484684
-
TRPV-5 mediates a receptor activator of NF-kappaB (RANK) ligand-induced increase in cytosolic Ca2+ in human osteoclasts and down-regulates bone resorption
-
Chamoux E, Bisson M, Payet MD, Roux S. TRPV-5 mediates a receptor activator of NF-kappaB (RANK) ligand-induced increase in cytosolic Ca2+ in human osteoclasts and down-regulates bone resorption. J Biol Chem. 2010;285(33):25354-25362.
-
(2010)
J Biol Chem
, vol.285
, Issue.33
, pp. 25354-25362
-
-
Chamoux, E.1
Bisson, M.2
Payet, M.D.3
Roux, S.4
-
23
-
-
0038758731
-
Involvement of capacitive calcium entry and calcium store refilling in osteoclastic survival and bone resorption process
-
Mentaverri R, Kamel S, Brazier M. Involvement of capacitive calcium entry and calcium store refilling in osteoclastic survival and bone resorption process. Cell Calcium. 2003;34(2):169-175.
-
(2003)
Cell Calcium
, vol.34
, Issue.2
, pp. 169-175
-
-
Mentaverri, R.1
Kamel, S.2
Brazier, M.3
-
24
-
-
79959794425
-
TRP channels as mediators of oxidative stress
-
Miller BA, Zhang W. TRP channels as mediators of oxidative stress. Adv Exp Med Biol. 2011;704:531-544.
-
(2011)
Adv Exp Med Biol
, vol.704
, pp. 531-544
-
-
Miller, B.A.1
Zhang, W.2
-
25
-
-
77958495432
-
Upregulation of Nox4 by TGF{beta}1 oxidizes SERCA and inhibits NO in arterial smooth muscle of the prediabetic Zucker rat
-
Tong X, Hou X, Jourd'heuil D, Weisbrod RM, Cohen RA. Upregulation of Nox4 by TGF{beta}1 oxidizes SERCA and inhibits NO in arterial smooth muscle of the prediabetic Zucker rat. Circ Res. 2010; 107(8):975-983.
-
(2010)
Circ Res
, vol.107
, Issue.8
, pp. 975-983
-
-
Tong, X.1
Hou, X.2
Jourd'Heuil, D.3
Weisbrod, R.M.4
Cohen, R.A.5
-
26
-
-
2442520434
-
Involvement of calcineurin in transforming growth factorbeta-mediated regulation of extracellular matrix accumulation
-
Gooch JL, Gorin Y, Zhang BX, Abboud HE. Involvement of calcineurin in transforming growth factorbeta-mediated regulation of extracellular matrix accumulation. J Biol Chem. 2004;279(15):15561-15570.
-
(2004)
J Biol Chem
, vol.279
, Issue.15
, pp. 15561-15570
-
-
Gooch, J.L.1
Gorin, Y.2
Zhang, B.X.3
Abboud, H.E.4
-
27
-
-
77951213242
-
RANKL-mediated reactive oxygen species pathway that induces long lasting Ca2+ oscillations essential for osteoclastogenesis
-
Kim MS, et al. RANKL-mediated reactive oxygen species pathway that induces long lasting Ca2+ oscillations essential for osteoclastogenesis. J Biol Chem. 2010;285(10):6913-6921.
-
(2010)
J Biol Chem
, vol.285
, Issue.10
, pp. 6913-6921
-
-
Kim, M.S.1
-
28
-
-
0032577483
-
Regulation of the calmodulin-stimulated protein phosphatase, calcineurin
-
Klee CB, Ren H, Wang X. Regulation of the calmodulin-stimulated protein phosphatase, calcineurin. J Biol Chem. 1998;273(22):13367-13370.
-
(1998)
J Biol Chem
, vol.273
, Issue.22
, pp. 13367-13370
-
-
Klee, C.B.1
Ren, H.2
Wang, X.3
-
29
-
-
70449560459
-
Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: A genome-wide evaluation of 13 974 participants in the Women's Genome Health Study
-
Pare G, et al. Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: a genome-wide evaluation of 13 974 participants in the Women's Genome Health Study. Circ Cardiovasc Genet. 2009;2:142-150.
-
(2009)
Circ Cardiovasc Genet
, vol.2
, pp. 142-150
-
-
Pare, G.1
-
30
-
-
27744432009
-
Autoamplification of NFATc1 expression determines its essential role in bone homeostasis
-
Asagiri M, et al. Autoamplification of NFATc1 expression determines its essential role in bone homeostasis. J Exp Med. 2005;202(9):1261-1269.
-
(2005)
J Exp Med
, vol.202
, Issue.9
, pp. 1261-1269
-
-
Asagiri, M.1
-
31
-
-
33750915802
-
Regulation of signal transduction through protein cysteine oxidation
-
Cross JV, Templeton DJ. Regulation of signal transduction through protein cysteine oxidation. Antioxid Redox Signal. 2006;8(9-10):1819-1827.
-
(2006)
Antioxid Redox Signal
, vol.8
, Issue.9-10
, pp. 1819-1827
-
-
Cross, J.V.1
Templeton, D.J.2
-
32
-
-
12744260290
-
Expression of Nox4 in osteoclasts
-
Yang S, Zhang Y, Ries W, Key L. Expression of Nox4 in osteoclasts. J Cell Biochem. 2004;92(2):238-248.
-
(2004)
J Cell Biochem
, vol.92
, Issue.2
, pp. 238-248
-
-
Yang, S.1
Zhang, Y.2
Ries, W.3
Key, L.4
-
33
-
-
77952407681
-
Oxidative modification of nuclear mitogen-activated protein kinase phosphatase 1 is involved in transforming growth factor beta1-induced expression of plasminogen activator inhibitor 1 in fibroblasts
-
Liu RM, et al. Oxidative modification of nuclear mitogen-activated protein kinase phosphatase 1 is involved in transforming growth factor beta1-induced expression of plasminogen activator inhibitor 1 in fibroblasts. J Biol Chem. 2010;285(21):16239-16247.
-
(2010)
J Biol Chem
, vol.285
, Issue.21
, pp. 16239-16247
-
-
Liu, R.M.1
-
34
-
-
73549120650
-
Role of MKP-1 in osteoclasts and bone homeostasis
-
Carlson J, et al. Role of MKP-1 in osteoclasts and bone homeostasis. Am J Pathol. 2009;175(4):1564-1573.
-
(2009)
Am J Pathol
, vol.175
, Issue.4
, pp. 1564-1573
-
-
Carlson, J.1
-
35
-
-
84866950669
-
Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent
-
Aoyama T, et al. Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent. Hepatology. 2012;56(6):2316-2327.
-
(2012)
Hepatology
, vol.56
, Issue.6
, pp. 2316-2327
-
-
Aoyama, T.1
-
36
-
-
80052030972
-
Aging and osteoarthritis
-
Loeser RF. Aging and osteoarthritis. Curr Opin Rheumatol. 2011;23(5):492-496.
-
(2011)
Curr Opin Rheumatol
, vol.23
, Issue.5
, pp. 492-496
-
-
Loeser, R.F.1
-
37
-
-
30444446380
-
Molecularly-defined lactose malabsorption, milk consumption and anthropometric differences in adult males
-
Gugatschka M, et al. Molecularly-defined lactose malabsorption, milk consumption and anthropometric differences in adult males. QJM. 2005;98(12):857-863.
-
(2005)
QJM
, vol.98
, Issue.12
, pp. 857-863
-
-
Gugatschka, M.1
-
38
-
-
78149239505
-
NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis
-
Zhang M, et al. NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis. Proc Natl Acad Sci U S A. 2010;107(42):18121-18126.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.42
, pp. 18121-18126
-
-
Zhang, M.1
-
39
-
-
0033571243
-
Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: Comparison of the recombinase activity of the tamoxifeninducible Cre-ER(T) and Cre-ER(T2) recombinases
-
Indra AK, et al. Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifeninducible Cre-ER(T) and Cre-ER(T2) recombinases. Nucleic Acids Res. 1999;27(22):4324-4327.
-
(1999)
Nucleic Acids Res
, vol.27
, Issue.22
, pp. 4324-4327
-
-
Indra, A.K.1
-
40
-
-
67349238305
-
Inhibition of osteoblastic bone formation by nuclear factor-kappaB
-
Chang J, et al. Inhibition of osteoblastic bone formation by nuclear factor-kappaB. Nat Med. 2009; 15(6):682-689.
-
(2009)
Nat Med
, vol.15
, Issue.6
, pp. 682-689
-
-
Chang, J.1
|