Endoplasmic reticulum-associated ubiquitin-conjugating enzyme Ube2j1 is a novel substrate of MK2 (MAPKAP kinase-2) involved in MK2-mediated TNFα production

Biochemical Journal

Volumn 456, Issue 2, 2013, Pages 163-172

  Menon, Manoj B ^a   Tiedje, Christopher ^a   Lafera, Juri ^a   Ronkina, Natalia ^a   Konen, Timo ^a   Kotlyarov, Alexey ^a   Gaestel, Matthias ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Endoplasmic reticulum associated degradation (ERAD); MAPK activated protein (MAPKAP) kinase 2; P38; Tumour necrosis factor (TNF); Ube2j1; Ubiquitin proteasome system

Indexed keywords

CYTOKINE; ENDOPLASMIC RETICULUM ASSOCIATED UBIQUITIN CONJUGATING ENZYME UBE2J1; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; TUMOR NECROSIS FACTOR ALPHA; UBIQUITIN CONJUGATING ENZYME; UNCLASSIFIED DRUG;

ARTICLE; ASSAY; BIOSYNTHESIS; CELL STRAIN HEK293; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; MUTANT; PHOSPHOPROTEOMICS; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEOMICS; STRESS; WILD TYPE;

ANIMALS; CELL LINE; ENDOPLASMIC RETICULUM STRESS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-SERINE-THREONINE KINASES; PROTEOLYSIS; STRESS, PHYSIOLOGICAL; TOLL-LIKE RECEPTORS; TUMOR NECROSIS FACTOR-ALPHA; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITINATION;

EID: 84887463103     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20130755     Document Type: Article

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