메뉴 건너뛰기




Volumn 12, Issue , 2012, Pages

ZIC1 modulates cell-cycle distributions and cell migration through regulation of sonic hedgehog, PI3K and MAPK signaling pathways in gastric cancer

Author keywords

Cell cycle; Sonic hedgehog; Tumour suppressor; Zic1

Indexed keywords

COMPLEMENTARY DNA; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ZIC1; UNCLASSIFIED DRUG;

EID: 84864627156     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-12-290     Document Type: Article
Times cited : (44)

References (35)
  • 1
    • 0027960488 scopus 로고
    • A novel zinc finger protein, zic, is involved in neurogenesis, especially in the cell lineage of cerebellar granule cells
    • Aruga J, Yokota N, Hashimoto M, Furuichi T, Fukuda M, Mikoshiba K. A novel zinc finger protein, zic, is involved in neurogenesis, especially in the cell lineage of cerebellar granule cells. J Neurochem 1994, 63(5):1880-1890.
    • (1994) J Neurochem , vol.63 , Issue.5 , pp. 1880-1890
    • Aruga, J.1    Yokota, N.2    Hashimoto, M.3    Furuichi, T.4    Fukuda, M.5    Mikoshiba, K.6
  • 2
    • 34247332335 scopus 로고    scopus 로고
    • Emerging roles for zic genes in early development
    • 10.1002/dvdy.21098, 17330889
    • Merzdorf CS. Emerging roles for zic genes in early development. Dev Dyn 2007, 236(4):922-940. 10.1002/dvdy.21098, 17330889.
    • (2007) Dev Dyn , vol.236 , Issue.4 , pp. 922-940
    • Merzdorf, C.S.1
  • 4
    • 35348867522 scopus 로고    scopus 로고
    • ZIC1 gene expression is controlled by DNA and histone methylation in mesenchymal proliferations
    • 10.1016/j.febslet.2007.09.061, 17936758
    • Pourebrahim R, Van Dam K, Bauters M, De Wever I, Sciot R, Cassiman JJ, Tejpar S. ZIC1 gene expression is controlled by DNA and histone methylation in mesenchymal proliferations. Febs Lett 2007, 581(26):5122-5126. 10.1016/j.febslet.2007.09.061, 17936758.
    • (2007) Febs Lett , vol.581 , Issue.26 , pp. 5122-5126
    • Pourebrahim, R.1    Van Dam, K.2    Bauters, M.3    De Wever, I.4    Sciot, R.5    Cassiman, J.J.6    Tejpar, S.7
  • 5
    • 33947507141 scopus 로고    scopus 로고
    • Identification of molecular markers and signaling pathway in endometrial cancer in Hong Kong Chinese women by genome-wide gene expression profiling
    • 10.1038/sj.onc.1209986, 17043662
    • Wong YF, Cheung TH, Lo KW, Yim SF, Siu NS, Chan SC, Ho TW, Wong KW, Yu MY, Wang VW, et al. Identification of molecular markers and signaling pathway in endometrial cancer in Hong Kong Chinese women by genome-wide gene expression profiling. Oncogene 2007, 26(13):1971-1982. 10.1038/sj.onc.1209986, 17043662.
    • (2007) Oncogene , vol.26 , Issue.13 , pp. 1971-1982
    • Wong, Y.F.1    Cheung, T.H.2    Lo, K.W.3    Yim, S.F.4    Siu, N.S.5    Chan, S.C.6    Ho, T.W.7    Wong, K.W.8    Yu, M.Y.9    Wang, V.W.10
  • 7
    • 79951922993 scopus 로고    scopus 로고
    • ZIC1 is downregulated through promoter hypermethylation, and functions as a tumor suppressor gene in colorectal cancer
    • 10.1371/journal.pone.0016916, 3039653, 21347233
    • Gan L, Chen S, Zhong J, Wang X, Lam EK, Liu X, Zhang J, Zhou T, Yu J, Si J, et al. ZIC1 is downregulated through promoter hypermethylation, and functions as a tumor suppressor gene in colorectal cancer. PLoS One 2011, 6(2):e16916. 10.1371/journal.pone.0016916, 3039653, 21347233.
    • (2011) PLoS One , vol.6 , Issue.2
    • Gan, L.1    Chen, S.2    Zhong, J.3    Wang, X.4    Lam, E.K.5    Liu, X.6    Zhang, J.7    Zhou, T.8    Yu, J.9    Si, J.10
  • 9
    • 2342628902 scopus 로고    scopus 로고
    • The role of Zic genes in neural development
    • 10.1016/j.mcn.2004.01.004, 15207846
    • Aruga J. The role of Zic genes in neural development. Mol Cell Neurosci 2004, 26(2):205-221. 10.1016/j.mcn.2004.01.004, 15207846.
    • (2004) Mol Cell Neurosci , vol.26 , Issue.2 , pp. 205-221
    • Aruga, J.1
  • 10
    • 27844472511 scopus 로고    scopus 로고
    • Causes of cancer in the world: comparative risk assessment of nine behavioural and environmental risk factors
    • 10.1016/S0140-6736(05)67725-2, 16298215
    • Danaei G, Vander HS, Lopez AD, Murray CJ, Ezzati M. Causes of cancer in the world: comparative risk assessment of nine behavioural and environmental risk factors. Lancet 2005, 366(9499):1784-1793. 10.1016/S0140-6736(05)67725-2, 16298215.
    • (2005) Lancet , vol.366 , Issue.9499 , pp. 1784-1793
    • Danaei, G.1    Vander, H.S.2    Lopez, A.D.3    Murray, C.J.4    Ezzati, M.5
  • 11
    • 0043200978 scopus 로고    scopus 로고
    • Gastric cancer
    • 10.1016/S0140-6736(03)13975-X, 12892963
    • Hohenberger P, Gretschel S. Gastric cancer. Lancet 2003, 362(9380):305-315. 10.1016/S0140-6736(03)13975-X, 12892963.
    • (2003) Lancet , vol.362 , Issue.9380 , pp. 305-315
    • Hohenberger, P.1    Gretschel, S.2
  • 12
    • 77954027650 scopus 로고    scopus 로고
    • Dysregulation of cellular signaling in gastric cancer
    • 10.1016/j.canlet.2010.04.025, 20488613
    • Wu WK, Cho CH, Lee CW, Fan D, Wu K, Yu J, Sung JJ. Dysregulation of cellular signaling in gastric cancer. Cancer Lett 2010, 295(2):144-153. 10.1016/j.canlet.2010.04.025, 20488613.
    • (2010) Cancer Lett , vol.295 , Issue.2 , pp. 144-153
    • Wu, W.K.1    Cho, C.H.2    Lee, C.W.3    Fan, D.4    Wu, K.5    Yu, J.6    Sung, J.J.7
  • 13
    • 27144541492 scopus 로고    scopus 로고
    • Frequent activation of the hedgehog pathway in advanced gastric adenocarcinomas
    • 10.1093/carcin/bgi130, 15905200
    • Ma X, Chen K, Huang S, Zhang X, Adegboyega PA, Evers BM, Zhang H, Xie J. Frequent activation of the hedgehog pathway in advanced gastric adenocarcinomas. Carcinogenesis 2005, 26(10):1698-1705. 10.1093/carcin/bgi130, 15905200.
    • (2005) Carcinogenesis , vol.26 , Issue.10 , pp. 1698-1705
    • Ma, X.1    Chen, K.2    Huang, S.3    Zhang, X.4    Adegboyega, P.A.5    Evers, B.M.6    Zhang, H.7    Xie, J.8
  • 14
    • 0027756145 scopus 로고
    • Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity
    • 10.1016/0092-8674(93)90627-3, 7916661
    • Echelard Y, Epstein DJ, St-Jacques B, Shen L, Mohler J, McMahon JA, McMahon AP. Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell 1993, 75(7):1417-1430. 10.1016/0092-8674(93)90627-3, 7916661.
    • (1993) Cell , vol.75 , Issue.7 , pp. 1417-1430
    • Echelard, Y.1    Epstein, D.J.2    St-Jacques, B.3    Shen, L.4    Mohler, J.5    McMahon, J.A.6    McMahon, A.P.7
  • 15
    • 27744583597 scopus 로고    scopus 로고
    • Hedgehog signaling pathway and gastric cancer
    • 10.4161/cbt.4.10.2184, 16258256
    • Katoh Y, Katoh M. Hedgehog signaling pathway and gastric cancer. Cancer Biol Ther 2005, 4(10):1050-1054. 10.4161/cbt.4.10.2184, 16258256.
    • (2005) Cancer Biol Ther , vol.4 , Issue.10 , pp. 1050-1054
    • Katoh, Y.1    Katoh, M.2
  • 16
    • 77953362373 scopus 로고    scopus 로고
    • Hedgehog signaling and gastrointestinal cancer
    • 10.1016/j.bbamcr.2010.03.008, 20307590
    • Saqui-Salces M, Merchant JL. Hedgehog signaling and gastrointestinal cancer. Biochim Biophys Acta 2010, 1803(7):786-795. 10.1016/j.bbamcr.2010.03.008, 20307590.
    • (2010) Biochim Biophys Acta , vol.1803 , Issue.7 , pp. 786-795
    • Saqui-Salces, M.1    Merchant, J.L.2
  • 17
    • 67149139838 scopus 로고    scopus 로고
    • Zic-associated holoprosencephaly: zebrafish Zic1 controls midline formation and forebrain patterning by regulating Nodal, Hedgehog, and retinoic acid signaling
    • 10.1101/gad.517009, 2701571, 19528322
    • Maurus D, Harris WA. Zic-associated holoprosencephaly: zebrafish Zic1 controls midline formation and forebrain patterning by regulating Nodal, Hedgehog, and retinoic acid signaling. Genes Dev 2009, 23(12):1461-1473. 10.1101/gad.517009, 2701571, 19528322.
    • (2009) Genes Dev , vol.23 , Issue.12 , pp. 1461-1473
    • Maurus, D.1    Harris, W.A.2
  • 18
    • 0037090880 scopus 로고    scopus 로고
    • Zic1 promotes the expansion of dorsal neural progenitors in spinal cord by inhibiting neuronal differentiation
    • 10.1006/dbio.2002.0598, 11944941
    • Aruga J, Tohmonda T, Homma S, Mikoshiba K. Zic1 promotes the expansion of dorsal neural progenitors in spinal cord by inhibiting neuronal differentiation. Dev Biol 2002, 244(2):329-341. 10.1006/dbio.2002.0598, 11944941.
    • (2002) Dev Biol , vol.244 , Issue.2 , pp. 329-341
    • Aruga, J.1    Tohmonda, T.2    Homma, S.3    Mikoshiba, K.4
  • 19
    • 33749247193 scopus 로고    scopus 로고
    • The zic1 gene is an activator of Wnt signaling
    • 10.1387/ijdb.052110cm, 16892174
    • Merzdorf CS, Sive HL. The zic1 gene is an activator of Wnt signaling. Int J Dev Biol 2006, 50(7):611-617. 10.1387/ijdb.052110cm, 16892174.
    • (2006) Int J Dev Biol , vol.50 , Issue.7 , pp. 611-617
    • Merzdorf, C.S.1    Sive, H.L.2
  • 20
    • 0036139973 scopus 로고    scopus 로고
    • Zic2 controls cerebellar development in cooperation with Zic1
    • Aruga J, Inoue T, Hoshino J, Mikoshiba K. Zic2 controls cerebellar development in cooperation with Zic1. J Neurosci 2002, 22(1):218-225.
    • (2002) J Neurosci , vol.22 , Issue.1 , pp. 218-225
    • Aruga, J.1    Inoue, T.2    Hoshino, J.3    Mikoshiba, K.4
  • 21
    • 39049126024 scopus 로고    scopus 로고
    • Inhibitors of cyclin dependent kinases: useful targets for cancer treatment
    • 10.2174/156800908783497131, 18288944
    • Sharma PS, Sharma R, Tyagi R. Inhibitors of cyclin dependent kinases: useful targets for cancer treatment. Curr Cancer Drug Targets 2008, 8(1):53-75. 10.2174/156800908783497131, 18288944.
    • (2008) Curr Cancer Drug Targets , vol.8 , Issue.1 , pp. 53-75
    • Sharma, P.S.1    Sharma, R.2    Tyagi, R.3
  • 22
    • 66549121314 scopus 로고    scopus 로고
    • Expression of retinoblastoma and cyclin D1 in gastric carcinoma
    • 10.4149/neo_2009_01_63, 19152247
    • Arici DS, Tuncer E, Ozer H, Simek G, Koyuncu A. Expression of retinoblastoma and cyclin D1 in gastric carcinoma. Neoplasma 2009, 56(1):63-67. 10.4149/neo_2009_01_63, 19152247.
    • (2009) Neoplasma , vol.56 , Issue.1 , pp. 63-67
    • Arici, D.S.1    Tuncer, E.2    Ozer, H.3    Simek, G.4    Koyuncu, A.5
  • 23
    • 34247149015 scopus 로고    scopus 로고
    • The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention
    • 1851974, 17407548
    • Alao JP. The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention. Mol Cancer 2007, 6:24. 1851974, 17407548.
    • (2007) Mol Cancer , vol.6 , pp. 24
    • Alao, J.P.1
  • 24
    • 67649424560 scopus 로고    scopus 로고
    • P21 in cancer: intricate networks and multiple activities
    • 10.1038/nrc2657, 2722839, 19440234
    • Abbas T, Dutta A. p21 in cancer: intricate networks and multiple activities. Nat Rev Cancer 2009, 9(6):400-414. 10.1038/nrc2657, 2722839, 19440234.
    • (2009) Nat Rev Cancer , vol.9 , Issue.6 , pp. 400-414
    • Abbas, T.1    Dutta, A.2
  • 25
    • 28244447471 scopus 로고    scopus 로고
    • P53-Independent negative regulation of p21/cyclin-dependent kinase-interacting protein 1 by the sonic hedgehog-glioma-associated oncogene 1 pathway in gastric carcinoma cells
    • 10.1158/0008-5472.CAN-05-0777, 16322228
    • Ohta M, Tateishi K, Kanai F, Watabe H, Kondo S, Guleng B, Tanaka Y, Asaoka Y, Jazag A, Imamura J, et al. p53-Independent negative regulation of p21/cyclin-dependent kinase-interacting protein 1 by the sonic hedgehog-glioma-associated oncogene 1 pathway in gastric carcinoma cells. Cancer Res 2005, 65(23):10822-10829. 10.1158/0008-5472.CAN-05-0777, 16322228.
    • (2005) Cancer Res , vol.65 , Issue.23 , pp. 10822-10829
    • Ohta, M.1    Tateishi, K.2    Kanai, F.3    Watabe, H.4    Kondo, S.5    Guleng, B.6    Tanaka, Y.7    Asaoka, Y.8    Jazag, A.9    Imamura, J.10
  • 26
    • 79952559236 scopus 로고    scopus 로고
    • Antiproliferative mechanism of a cannabinoid agonist by cell cycle arrest in human gastric cancer cells
    • 10.1002/jcb.23041, 21312237
    • Park JM, Xian XS, Choi MG, Park H, Cho YK, Lee IS, Kim SW, Chung IS. Antiproliferative mechanism of a cannabinoid agonist by cell cycle arrest in human gastric cancer cells. J Cell Biochem 2011, 112(4):1192-1205. 10.1002/jcb.23041, 21312237.
    • (2011) J Cell Biochem , vol.112 , Issue.4 , pp. 1192-1205
    • Park, J.M.1    Xian, X.S.2    Choi, M.G.3    Park, H.4    Cho, Y.K.5    Lee, I.S.6    Kim, S.W.7    Chung, I.S.8
  • 27
    • 0142227025 scopus 로고    scopus 로고
    • Developmental biology informs cancer: the emerging role of the hedgehog signaling pathway in upper gastrointestinal cancers
    • 10.1016/S1535-6108(03)00246-0, 14585350
    • Xie K, Abbruzzese JL. Developmental biology informs cancer: the emerging role of the hedgehog signaling pathway in upper gastrointestinal cancers. Cancer Cell 2003, 4(4):245-247. 10.1016/S1535-6108(03)00246-0, 14585350.
    • (2003) Cancer Cell , vol.4 , Issue.4 , pp. 245-247
    • Xie, K.1    Abbruzzese, J.L.2
  • 28
    • 0034738979 scopus 로고    scopus 로고
    • Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine
    • 10.1038/35023008, 10984056
    • Taipale J, Chen JK, Cooper MK, Wang B, Mann RK, Milenkovic L, Scott MP, Beachy PA. Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine. Nature 2000, 406(6799):1005-1009. 10.1038/35023008, 10984056.
    • (2000) Nature , vol.406 , Issue.6799 , pp. 1005-1009
    • Taipale, J.1    Chen, J.K.2    Cooper, M.K.3    Wang, B.4    Mann, R.K.5    Milenkovic, L.6    Scott, M.P.7    Beachy, P.A.8
  • 29
    • 51649094216 scopus 로고    scopus 로고
    • ZIC antibodies in paraneoplastic cerebellar degeneration and small cell lung cancer
    • Sabater L, Bataller L, Suarez-Calvet M, Saiz A, Dalmau J, Graus F. ZIC antibodies in paraneoplastic cerebellar degeneration and small cell lung cancer. J Neuroimmunol 2008, 201-202:163-165.
    • (2008) J Neuroimmunol , vol.201-202 , pp. 163-165
    • Sabater, L.1    Bataller, L.2    Suarez-Calvet, M.3    Saiz, A.4    Dalmau, J.5    Graus, F.6
  • 30
    • 34547208851 scopus 로고    scopus 로고
    • ERK implication in cell cycle regulation
    • 10.1016/j.bbamcr.2006.11.010, 17188374
    • Chambard JC, Lefloch R, Pouyssegur J, Lenormand P. ERK implication in cell cycle regulation. Biochim Biophys Acta 2007, 1773(8):1299-1310. 10.1016/j.bbamcr.2006.11.010, 17188374.
    • (2007) Biochim Biophys Acta , vol.1773 , Issue.8 , pp. 1299-1310
    • Chambard, J.C.1    Lefloch, R.2    Pouyssegur, J.3    Lenormand, P.4
  • 31
    • 38949143728 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway in human cancer: genetic alterations and therapeutic implications
    • 10.2174/138920207782446160, 2652403, 19384426
    • Arcaro A, Guerreiro AS. The phosphoinositide 3-kinase pathway in human cancer: genetic alterations and therapeutic implications. Curr Genomics 2007, 8(5):271-306. 10.2174/138920207782446160, 2652403, 19384426.
    • (2007) Curr Genomics , vol.8 , Issue.5 , pp. 271-306
    • Arcaro, A.1    Guerreiro, A.S.2
  • 32
    • 34247612847 scopus 로고    scopus 로고
    • Targeting cell cycle kinases for cancer therapy
    • 10.2174/092986707780362925, 17439397
    • de Carcer G, Perez DCI, Malumbres M. Targeting cell cycle kinases for cancer therapy. Curr Med Chem 2007, 14(9):969-985. 10.2174/092986707780362925, 17439397.
    • (2007) Curr Med Chem , vol.14 , Issue.9 , pp. 969-985
    • de Carcer, G.1    Perez, D.C.I.2    Malumbres, M.3
  • 34
    • 40949137792 scopus 로고    scopus 로고
    • Sonic hedgehog signaling promotes motility and invasiveness of gastric cancer cells through TGF-beta-mediated activation of the ALK5-Smad 3 pathway
    • Yoo YA, Kang MH, Kim JS, Oh SC. Sonic hedgehog signaling promotes motility and invasiveness of gastric cancer cells through TGF-beta-mediated activation of the ALK5-Smad 3 pathway. Carcinogenesis 2008, 29(3):480-490.
    • (2008) Carcinogenesis , vol.29 , Issue.3 , pp. 480-490
    • Yoo, Y.A.1    Kang, M.H.2    Kim, J.S.3    Oh, S.C.4
  • 35
    • 0035831529 scopus 로고    scopus 로고
    • Physical and functional interactions between Zic and Gli proteins
    • 10.1074/jbc.C000773200, 11238441
    • Koyabu Y, Nakata K, Mizugishi K, Aruga J, Mikoshiba K. Physical and functional interactions between Zic and Gli proteins. J Biol Chem 2001, 276(10):6889-6892. 10.1074/jbc.C000773200, 11238441.
    • (2001) J Biol Chem , vol.276 , Issue.10 , pp. 6889-6892
    • Koyabu, Y.1    Nakata, K.2    Mizugishi, K.3    Aruga, J.4    Mikoshiba, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.