-
1
-
-
48649108724
-
The prognostic importance of triple negative breast carcinoma
-
Mersin H, Yildirim E, Berberoglu U, et al. The prognostic importance of triple negative breast carcinoma. Breast 2008; 17: 341-6.
-
(2008)
Breast
, vol.17
, pp. 341-346
-
-
Mersin, H.1
Yildirim, E.2
Berberoglu, U.3
-
3
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
DOI 10.1073/pnas.191367098
-
SÃ?rlie T, Perou CM, Tibshirani R, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 2001; 98: 10869-74. (Pubitemid 32878711)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.19
, pp. 10869-10874
-
-
Sorlie, T.1
Perou, C.M.2
Tibshirani, R.3
Aas, T.4
Geisler, S.5
Johnsen, H.6
Hastie, T.7
Eisen, M.B.8
Van De Rijn, M.9
Jeffrey, S.S.10
Thorsen, T.11
Quist, H.12
Matese, J.C.13
Brown, P.O.14
Botstein, D.15
Lonning, P.E.16
Borresen-Dale, A.-L.17
-
4
-
-
79952253747
-
Incidence and outcome of BRCA mutations in unselected patients with triple receptor-negative breast cancer
-
Gonzalez-Angulo AM, Timms KM, Liu S, et al. Incidence and outcome of BRCA mutations in unselected patients with triple receptor-negative breast cancer. Clin Cancer Res 2011; 17: 1082-9.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 1082-1089
-
-
Gonzalez-Angulo, A.M.1
Timms, K.M.2
Liu, S.3
-
5
-
-
84861323251
-
Prevalence of BRCA mutations in an unselected population of triple-negative breast cancer
-
Hartman AR, Kaldate RR, Sailer LM, et al. Prevalence of BRCA mutations in an unselected population of triple-negative breast cancer. Cancer 2012; 118: 2787-95.
-
(2012)
Cancer
, vol.118
, pp. 2787-2795
-
-
Hartman, A.R.1
Kaldate, R.R.2
Sailer, L.M.3
-
6
-
-
84863984125
-
Prevalence of BRCA1 mutations among 403 women with triple-negative breast cancer: Implications for genetic screening selection criteria: A Hellenic Cooperative Oncology Group Study
-
Fostira F, Tsitlaidou M, Papadimitriou C, et al. Prevalence of BRCA1 mutations among 403 women with triple-negative breast cancer: implications for genetic screening selection criteria: a Hellenic Cooperative Oncology Group Study. Breast Cancer Res Treat 2012; 134: 353-62.
-
(2012)
Breast Cancer Res Treat
, vol.134
, pp. 353-362
-
-
Fostira, F.1
Tsitlaidou, M.2
Papadimitriou, C.3
-
7
-
-
84858295021
-
BRCA1 testing should be offered to individuals with triple-negative breast cancer diagnosed below 50 years
-
Robertson L, Hanson H, Seal S, et al. BRCA1 testing should be offered to individuals with triple-negative breast cancer diagnosed below 50 years. Br J Cancer 2012; 106: 1234-8.
-
(2012)
Br J Cancer
, vol.106
, pp. 1234-1238
-
-
Robertson, L.1
Hanson, H.2
Seal, S.3
-
8
-
-
64749086562
-
The prevalence of BRCA1 mutations among young women with triple-negative breast cancer
-
Young SR, Pilarski RT, Donenberg T, et al. The prevalence of BRCA1 mutations among young women with triple-negative breast cancer. BMC Cancer 2009; 9: 86.
-
(2009)
BMC Cancer
, vol.9
, pp. 86
-
-
Young, S.R.1
Pilarski, R.T.2
Donenberg, T.3
-
9
-
-
84868217990
-
Triple-negative breast cancer and PTEN (phosphatase and tensin homologue) loss are predictors of BRCA1 germline mutations in women with early-onset and familial breast cancer, but not in women with isolated late-onset breast cancer
-
Phuah SY, Looi LM, Hassan N, et al. Triple-negative breast cancer and PTEN (phosphatase and tensin homologue) loss are predictors of BRCA1 germline mutations in women with early-onset and familial breast cancer, but not in women with isolated late-onset breast cancer. Breast Cancer Res 2012; 14: R142.
-
(2012)
Breast Cancer Res
, vol.14
-
-
Phuah, S.Y.1
Looi, L.M.2
Hassan, N.3
-
10
-
-
33745200945
-
Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2
-
Xia B, Sheng Q, Nakanishi K, et al. Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2. Mol Cell 2006; 22: 719-29.
-
(2006)
Mol Cell
, vol.22
, pp. 719-729
-
-
Xia, B.1
Sheng, Q.2
Nakanishi, K.3
-
11
-
-
66349096607
-
PALB2 is an integral component of the BRCA complex required for homologous recombination repair
-
Sy SM, Huen MS, Chen J,. PALB2 is an integral component of the BRCA complex required for homologous recombination repair. Proc Natl Acad Sci USA 2009; 106: 7155-60.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 7155-7160
-
-
Sy, S.M.1
Huen, M.S.2
Chen, J.3
-
12
-
-
33846625493
-
PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene
-
DOI 10.1038/ng1959, PII NG1959
-
Rahman N, Seal S, Thompson D, et al. PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene. Nat Genet 2007; 39: 165-7. (Pubitemid 46184346)
-
(2007)
Nature Genetics
, vol.39
, Issue.2
, pp. 165-167
-
-
Rahman, N.1
Seal, S.2
Thompson, D.3
Kelly, P.4
Renwick, A.5
Elliott, A.6
Reid, S.7
Spanova, K.8
Barfoot, R.9
Chagtai, T.10
Jayatilake, H.11
McGuffog, L.12
Hanks, S.13
Evans, D.G.14
Eccles, D.15
Easton, D.F.16
Stratton, M.R.17
-
13
-
-
79958282990
-
BRIP1, PALB2, and RAD51C mutation analysis reveals their relative importance as genetic susceptibility factors for breast cancer
-
Wong MW, Nordfors C, Mossman D, et al. BRIP1, PALB2, and RAD51C mutation analysis reveals their relative importance as genetic susceptibility factors for breast cancer. Breast Cancer Res Treat 2011; 127: 853-9.
-
(2011)
Breast Cancer Res Treat
, vol.127
, pp. 853-859
-
-
Wong, M.W.1
Nordfors, C.2
Mossman, D.3
-
14
-
-
77957329128
-
PALB2/FANCN: Recombining cancer and Fanconi anemia
-
Tischkowitz M, Xia B,. PALB2/FANCN: recombining cancer and Fanconi anemia. Cancer Res 2010; 70: 7353-9.
-
(2010)
Cancer Res
, vol.70
, pp. 7353-7359
-
-
Tischkowitz, M.1
Xia, B.2
-
15
-
-
79958123341
-
PALB2 mutations in familial breast and pancreatic cancer
-
Hofstatter EW, Domchek SM, Miron A, et al. PALB2 mutations in familial breast and pancreatic cancer. Fam Cancer 2011; 10: 225-31.
-
(2011)
Fam Cancer
, vol.10
, pp. 225-231
-
-
Hofstatter, E.W.1
Domchek, S.M.2
Miron, A.3
-
16
-
-
65649112112
-
The breast cancer susceptibility mutation PALB2 1592delT is associated with an aggressive tumor phenotype
-
Heikkinen T, Karkkainen H, Aaltonen K, et al. The breast cancer susceptibility mutation PALB2 1592delT is associated with an aggressive tumor phenotype. Clin Cancer Res 2009; 15: 3214-22.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3214-3222
-
-
Heikkinen, T.1
Karkkainen, H.2
Aaltonen, K.3
-
17
-
-
34249857115
-
Analysis of PALB2/FANCN-associated breast cancer families
-
DOI 10.1073/pnas.0701724104
-
Tischkowitz M, Xia B, Sabbaghian N, et al. Analysis of PALB2/FANCN-associated breast cancer families. Proc Natl Acad Sci USA 2007; 104: 6788-93. (Pubitemid 47175579)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.16
, pp. 6788-6793
-
-
Tischkowitz, M.1
Xia, B.2
Sabbaghian, N.3
Reis-Filho, J.S.4
Hamel, N.5
Li, G.6
Van Beers, E.H.7
Li, L.8
Khalil, T.9
Quenneville, L.A.10
Omeroglu, A.11
Poll, A.12
Lepage, P.13
Wong, N.14
Nederlof, P.M.15
Ashworth, A.16
Tonin, P.N.17
Narod, S.A.18
Livingston, D.M.19
Foulkes, W.D.20
more..
-
18
-
-
68149165614
-
Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm
-
Kumar P, Henikoff S, Ng PC,. Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm. Nat Protoc 2009; 4: 1073-81.
-
(2009)
Nat Protoc
, vol.4
, pp. 1073-1081
-
-
Kumar, P.1
Henikoff, S.2
Ng, P.C.3
-
19
-
-
0043122919
-
SIFT: Predicting amino acid changes that affect protein function
-
DOI 10.1093/nar/gkg509
-
Ng PC, Henikoff S. SIFT,: predicting amino acid changes that affect protein function. Nucleic Acids Res 2003; 31: 3812-14. (Pubitemid 37442253)
-
(2003)
Nucleic Acids Research
, vol.31
, Issue.13
, pp. 3812-3814
-
-
Ng, P.C.1
Henikoff, S.2
-
20
-
-
79957608461
-
Germline mutations in the PALB2 gene are population specific and occur with low frequencies in familial breast cancer
-
Hellebrand H, Sutter C, Honisch E, et al. Germline mutations in the PALB2 gene are population specific and occur with low frequencies in familial breast cancer. Hum Mutat 2011; 32: E2176-E2188.
-
(2011)
Hum Mutat
, vol.32
-
-
Hellebrand, H.1
Sutter, C.2
Honisch, E.3
-
21
-
-
84857918420
-
Detection of a large rearrangement in PALB2 in Spanish breast cancer families with male breast cancer
-
Blanco A, de la Hoya M, Balmana J, et al. Detection of a large rearrangement in PALB2 in Spanish breast cancer families with male breast cancer. Breast Cancer Res Treat 2012; 132: 307-15.
-
(2012)
Breast Cancer Res Treat
, vol.132
, pp. 307-315
-
-
Blanco, A.1
De La Hoya, M.2
Balmana, J.3
-
22
-
-
58549086980
-
Analysis of FANCB and FANCN/PALB2 fanconi anemia genes in BRCA1/2-negative Spanish breast cancer families
-
Garcia MJ, Fernandez V, Osorio A, et al. Analysis of FANCB and FANCN/PALB2 fanconi anemia genes in BRCA1/2-negative Spanish breast cancer families. Breast Cancer Res Treat 2009; 113: 545-51.
-
(2009)
Breast Cancer Res Treat
, vol.113
, pp. 545-551
-
-
Garcia, M.J.1
Fernandez, V.2
Osorio, A.3
-
23
-
-
77953534887
-
PALB2 mutations in male breast cancer: A population-based study in Central Italy
-
Silvestri V, Rizzolo P, Zanna I, et al. PALB2 mutations in male breast cancer: a population-based study in Central Italy. Breast Cancer Res Treat 2010; 122: 299-301.
-
(2010)
Breast Cancer Res Treat
, vol.122
, pp. 299-301
-
-
Silvestri, V.1
Rizzolo, P.2
Zanna, I.3
-
24
-
-
77649148280
-
A novel germline PALB2 deletion in Polish breast and ovarian cancer patients
-
Dansonka-Mieszkowska A, Kluska A, Moes J, et al. A novel germline PALB2 deletion in Polish breast and ovarian cancer patients. BMC Med Genet 2010; 11: 20.
-
(2010)
BMC Med Genet
, vol.11
, pp. 20
-
-
Dansonka-Mieszkowska, A.1
Kluska, A.2
Moes, J.3
-
25
-
-
40349111045
-
Identification of a novel truncating PALB2 mutation and analysis of its contribution to early-onset breast cancer in French-Canadian women
-
Foulkes WD, Ghadirian P, Akbari MR, et al. Identification of a novel truncating PALB2 mutation and analysis of its contribution to early-onset breast cancer in French-Canadian women. Breast Cancer Res 2007; 9: R83.
-
(2007)
Breast Cancer Res
, vol.9
-
-
Foulkes, W.D.1
Ghadirian, P.2
Akbari, M.R.3
-
26
-
-
79151476244
-
Germline mutations in PALB2 in African-American breast cancer cases
-
Ding YC, Steele L, Chu LH, et al. Germline mutations in PALB2 in African-American breast cancer cases. Breast Cancer Res Treat 2011; 126: 227-30.
-
(2011)
Breast Cancer Res Treat
, vol.126
, pp. 227-230
-
-
Ding, Y.C.1
Steele, L.2
Chu, L.H.3
-
27
-
-
42949174531
-
Analysis of the gene coding for the BRCA2-interacting protein PALB2 in hereditary prostate cancer
-
DOI 10.1002/pros.20729
-
Tischkowitz M, Sabbaghian N, Ray AM, et al. Analysis of the gene coding for the BRCA2-interacting protein PALB2 in hereditary prostate cancer. Prostate 2008; 68: 675-8. (Pubitemid 351614645)
-
(2008)
Prostate
, vol.68
, Issue.6
, pp. 675-678
-
-
Tischkowitz, M.1
Sabbaghian, N.2
Ray, A.M.3
Lange, E.M.4
Foulkes, W.D.5
Cooney, K.A.6
-
28
-
-
84860389325
-
Screening for BRCA1, BRCA2, CHEK2, PALB2, BRIP1, RAD50, and CDH1 mutations in high-risk Finnish BRCA1/2-founder mutation-negative breast and/or ovarian cancer individuals
-
Kuusisto KM, Bebel A, Vihinen M, et al. Screening for BRCA1, BRCA2, CHEK2, PALB2, BRIP1, RAD50, and CDH1 mutations in high-risk Finnish BRCA1/2-founder mutation-negative breast and/or ovarian cancer individuals. Breast Cancer Res 2011; 13: R20.
-
(2011)
Breast Cancer Res
, vol.13
-
-
Kuusisto, K.M.1
Bebel, A.2
Vihinen, M.3
-
29
-
-
70449523582
-
PALB2 sequence variants in young South African breast cancer patients
-
Sluiter M, Mew S, van Rensburg EJ,. PALB2 sequence variants in young South African breast cancer patients. Fam Cancer 2009; 8: 347-53.
-
(2009)
Fam Cancer
, vol.8
, pp. 347-353
-
-
Sluiter, M.1
Mew, S.2
Van Rensburg, E.J.3
-
30
-
-
79958732548
-
PALB2 mutations in German and Russian patients with bilateral breast cancer
-
Bogdanova N, Sokolenko AP, Iyevleva AG, et al. PALB2 mutations in German and Russian patients with bilateral breast cancer. Breast Cancer Res Treat 2011; 126: 545-50.
-
(2011)
Breast Cancer Res Treat
, vol.126
, pp. 545-550
-
-
Bogdanova, N.1
Sokolenko, A.P.2
Iyevleva, A.G.3
-
31
-
-
77955053607
-
A PALB2 germline mutation associated with hereditary breast cancer in Italy
-
Papi L, Putignano AL, Congregati C, et al. A PALB2 germline mutation associated with hereditary breast cancer in Italy. Fam Cancer 2010; 9: 181-5.
-
(2010)
Fam Cancer
, vol.9
, pp. 181-185
-
-
Papi, L.1
Putignano, A.L.2
Congregati, C.3
-
32
-
-
77955861787
-
Evaluation of the contribution of the three breast cancer susceptibility genes CHEK2, STK11, and PALB2 in non-BRCA1/2 French Canadian families with high risk of breast cancer
-
Guenard F, Pedneault CS, Ouellette G, et al. Evaluation of the contribution of the three breast cancer susceptibility genes CHEK2, STK11, and PALB2 in non-BRCA1/2 French Canadian families with high risk of breast cancer. Genet Test Mol Biomarkers 2010; 14: 515-26.
-
(2010)
Genet Test Mol Biomarkers
, vol.14
, pp. 515-526
-
-
Guenard, F.1
Pedneault, C.S.2
Ouellette, G.3
-
33
-
-
33846569450
-
Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer
-
DOI 10.1038/ng1947, PII NG1947
-
Reid S, Schindler D, Hanenberg H, et al. Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer. Nat Genet 2007; 39: 162-4. (Pubitemid 46184345)
-
(2007)
Nature Genetics
, vol.39
, Issue.2
, pp. 162-164
-
-
Reid, S.1
Schindler, D.2
Hanenberg, H.3
Barker, K.4
Hanks, S.5
Kalb, R.6
Neveling, K.7
Kelly, P.8
Seal, S.9
Freund, M.10
Wurm, M.11
Batish, S.D.12
Lach, F.P.13
Yetgin, S.14
Neitzel, H.15
Ariffin, H.16
Tischkowitz, M.17
Mathew, C.G.18
Auerbach, A.D.19
Rahman, N.20
more..
-
35
-
-
78650389153
-
A PALB2 mutation associated with high risk of breast cancer
-
Southey MC, Teo ZL, Dowty JG, et al. A PALB2 mutation associated with high risk of breast cancer. Breast Cancer Res 2010; 12: R109.
-
(2010)
Breast Cancer Res
, vol.12
-
-
Southey, M.C.1
Teo, Z.L.2
Dowty, J.G.3
-
36
-
-
69949169651
-
Structural basis for recruitment of BRCA2 by PALB2
-
Oliver AW, Swift S, Lord CJ, et al. Structural basis for recruitment of BRCA2 by PALB2. EMBO Rep 2009; 10: 990-6.
-
(2009)
EMBO Rep
, vol.10
, pp. 990-996
-
-
Oliver, A.W.1
Swift, S.2
Lord, C.J.3
-
37
-
-
62549115236
-
PALB2 links BRCA1 and BRCA2 in the DNA-damage response
-
Zhang F, Ma J, Wu J, et al. PALB2 links BRCA1 and BRCA2 in the DNA-damage response. Curr Biol 2009; 19: 524-9.
-
(2009)
Curr Biol
, vol.19
, pp. 524-529
-
-
Zhang, F.1
Ma, J.2
Wu, J.3
-
38
-
-
34447295643
-
Counting potentially functional variants in BRCA1, BRCA2 and ATM predicts breast cancer susceptibility
-
DOI 10.1093/hmg/ddm050
-
Johnson N, Fletcher O, Palles C, et al. Counting potentially functional variants in BRCA1, BRCA2 and ATM predicts breast cancer susceptibility. Hum Mol Genet 2007; 16: 1051-7. (Pubitemid 47062726)
-
(2007)
Human Molecular Genetics
, vol.16
, Issue.9
, pp. 1051-1057
-
-
Johnson, N.1
Fletcher, O.2
Palles, C.3
Rudd, M.4
Webb, E.5
Sellick, G.6
Dos Santos Silva, I.7
McCormack, V.8
Gibson, L.9
Fraser, A.10
Leonard, A.11
Gilham, C.12
Tavtigian, S.V.13
Sean, V.14
Ashworth, A.15
Houlston, R.16
Peto, J.17
-
39
-
-
84873696289
-
Whole exome sequencing suggests much of non-BRCA1/BRCA2 familial breast cancer is due to moderate and low penetrance susceptibility alleles
-
Gracia-Aznarez FJ, Fernandez V, Pita G, et al. Whole exome sequencing suggests much of non-BRCA1/BRCA2 familial breast cancer is due to moderate and low penetrance susceptibility alleles. PLoS One 2013; 8: e55681.
-
(2013)
PLoS One
, vol.8
-
-
Gracia-Aznarez, F.J.1
Fernandez, V.2
Pita, G.3
-
40
-
-
55749109888
-
Are the so-called low penetrance breast cancer genes, ATM, BRIP1, PALB2 and CHEK2, high risk for women with strong family histories?
-
Byrnes GB, Southey MC, Hopper JL,. Are the so-called low penetrance breast cancer genes, ATM, BRIP1, PALB2 and CHEK2, high risk for women with strong family histories? Breast Cancer Res 2008; 10: 208.
-
(2008)
Breast Cancer Res
, vol.10
, pp. 208
-
-
Byrnes, G.B.1
Southey, M.C.2
Hopper, J.L.3
-
41
-
-
58149234684
-
Therapeutic strategies for triple-negative breast cancer
-
Tan AR, Swain SM,. Therapeutic strategies for triple-negative breast cancer. Cancer J 2008; 14: 343-51.
-
(2008)
Cancer J
, vol.14
, pp. 343-351
-
-
Tan, A.R.1
Swain, S.M.2
-
42
-
-
70449645182
-
T1N0 triple negative breast cancer: Risk of recurrence and adjuvant chemotherapy
-
Kaplan HG, Malmgren JA, Atwood M,. T1N0 triple negative breast cancer: risk of recurrence and adjuvant chemotherapy. Breast J 2009; 15: 454-60.
-
(2009)
Breast J
, vol.15
, pp. 454-460
-
-
Kaplan, H.G.1
Malmgren, J.A.2
Atwood, M.3
-
43
-
-
67650471685
-
Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers
-
Fong PC, Boss DS, Yap TA, et al. Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers. N Engl J Med 2009; 361: 123-34.
-
(2009)
N Engl J Med
, vol.361
, pp. 123-134
-
-
Fong, P.C.1
Boss, D.S.2
Yap, T.A.3
-
44
-
-
77955019276
-
Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: A proof-of-concept trial
-
Tutt A, Robson M, Garber JE, et al. Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial. Lancet 2010; 376: 235-44.
-
(2010)
Lancet
, vol.376
, pp. 235-244
-
-
Tutt, A.1
Robson, M.2
Garber, J.E.3
-
45
-
-
77955066856
-
PARP inhibitors in BRCA1/BRCA2 germline mutation carriers with ovarian and breast cancer
-
10
-
Annunziata CM, Bates SE,. PARP inhibitors in BRCA1/BRCA2 germline mutation carriers with ovarian and breast cancer. F1000 Biol Rep 2010; 2: pii 10.
-
(2010)
F1000 Biol Rep
, vol.2
-
-
Annunziata, C.M.1
Bates, S.E.2
-
46
-
-
77957760669
-
Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination
-
Buisson R, Dion-Cote AM, Coulombe Y, et al. Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination. Nat Struct Mol Biol 2010; 17: 1247-54.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 1247-1254
-
-
Buisson, R.1
Dion-Cote, A.M.2
Coulombe, Y.3
-
47
-
-
79954560252
-
Synthetic lethality of PARP inhibition in cancers lacking BRCA1 and BRCA2 mutations
-
Dedes KJ, Wilkerson PM, Wetterskog D, et al. Synthetic lethality of PARP inhibition in cancers lacking BRCA1 and BRCA2 mutations. Cell Cycle 2011; 10: 1192-9.
-
(2011)
Cell Cycle
, vol.10
, pp. 1192-1199
-
-
Dedes, K.J.1
Wilkerson, P.M.2
Wetterskog, D.3
|