Counting potentially functional variants in BRCA1, BRCA2 and ATM predicts breast cancer susceptibility

Human Molecular Genetics

Volumn 16, Issue 9, 2007, Pages 1051-1057

  Johnson, Nichola ^a   Fletcher, Olivia ^a   Palles, Claire ^a   Rudd, Matthew ^a   Webb, Emily ^a   Sellick, Gabrielle ^a   dos Santos Silva, Isabel ^b   McCormack, Valerie ^b   Gibson, Lorna ^b   Fraser, Agnes ^b   Leonard, Angela ^b   Gilham, Clare ^a   Tavtigian, S V Sean V ^c   Ashworth, Alan ^a   Houlston, Richard ^a   Peto, Julian ^a,b  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; BRCA1 PROTEIN; BRCA2 PROTEIN; CHECKPOINT KINASE 2; PROTEIN P53;

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER RISK; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENE MUTATION; GENETIC ANALYSIS; GENETIC IDENTIFICATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HIGH RISK POPULATION; HUMAN; MAJOR CLINICAL STUDY; ONCOGENE; PRIORITY JOURNAL; SCORING SYSTEM; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL SIGNIFICANCE;

ADULT; AGED; BRCA1 PROTEIN; BRCA2 PROTEIN; BREAST NEOPLASMS; CELL CYCLE PROTEINS; DNA-BINDING PROTEINS; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN-SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 34447295643     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddm050     Document Type: Article

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