Germline mutations in the PALB2 gene are population specific and occur with low frequencies in familial breast cancer

Human Mutation

Volumn 32, Issue 6, 2011, Pages

  Hellebrand, Heide ^a   Sutter, Christian ^b   Honisch, Ellen ^c   Gross, Eva ^a   Wappenschmidt, Barbara ^d   Schem, Christian ^e   Deißler, Helmut ^f   Ditsch, Nina ^g   Gress, Verena ^a   Kiechle, Marion ^a   Bartram, Claus R ^b   Schmutzler, Rita K ^d   Niederacher, Dieter ^c   Arnold, Norbert ^e   Meindl, Alfons ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c HEINRICH HEINE UNIVERSITY   (Germany)

^d UNIVERSITY OF COLOGNE   (Germany)

^e UNIVERSITY OF KIEL   (Germany)

^f UNIVERSITY OF ULM   (Germany)

^g UNIVERSITY OF MUNICH   (Germany)

Author keywords

Breast cancer; DNA repair; PALB2; Population Genetics

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR;

ADULT; BREAST CANCER; CONTROLLED STUDY; FAMILIAL CANCER; FEMALE; GENE; GENETIC SCREENING; GERMANY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MISSENSE MUTATION; NOTE; NUCLEOTIDE SEQUENCE; PALB2 GENE; POPULATION GENETICS; PRIORITY JOURNAL; PROMOTER REGION;

ADULT; BRCA2 PROTEIN; BREAST NEOPLASMS; CODON, NONSENSE; DNA MUTATIONAL ANALYSIS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GERM-LINE MUTATION; GERMANY; HUMANS; MIDDLE AGED; MUTATION, MISSENSE; NUCLEAR PROTEINS; TUMOR SUPPRESSOR PROTEINS;

EID: 79957608461     PISSN: 10597794     EISSN: 10981004     Source Type: Journal    
DOI: 10.1002/humu.21478     Document Type: Note

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