Aberrant CpG Islands' hypermethylation of ABCB1 in mesenchymal stem cells of patients with steroid-associated osteonecrosis

Journal of Rheumatology

Volumn 40, Issue 11, 2013, Pages 1913-1920

  Sun, Zhibo ^a   Yang, Shuhua ^a   Ye, Shunan ^a   Zhang, Yukun ^a   Xu, Weihua ^a   Zhang, Bo ^a   Liu, Xianzhe ^a   Mo, Fengbo ^a   Hua, Wenbin ^a  

^a UNION HOSPITAL   (China)

Author keywords

ABCB1; HYPERMETHYLATION; MESENCHYMAL STEM CELLS; STEROID ASSOCIATED OSTEONECROSIS

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; GLUCOCORTICOID; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; REACTIVE OXYGEN METABOLITE;

ABCB1 GENE; ADULT; AGED; ANTIOXIDANT ACTIVITY; ARTICLE; CELL PROLIFERATION; CELL VIABILITY; CLINICAL ARTICLE; CONTROLLED STUDY; CPG ISLAND; DENSITY GRADIENT CENTRIFUGATION; DISEASE ASSOCIATION; DNA METHYLATION; DRUG INDUCED DISEASE; DRUG TARGETING; FEMALE; FEMUR HEAD NECROSIS; FEMUR NECK FRACTURE; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE IDENTIFICATION; GENETIC POLYMORPHISM; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MESENCHYMAL STEM CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION;

ABCB1; HYPERMETHYLATION; MESENCHYMAL STEM CELLS; STEROID-ASSOCIATED OSTEONECROSIS;

ADULT; AGED; CELL SURVIVAL; CPG ISLANDS; DNA METHYLATION; FEMALE; FEMUR HEAD NECROSIS; GLUCOCORTICOIDS; HUMANS; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MESENCHYMAL STROMAL CELLS; MIDDLE AGED; OXIDATIVE STRESS; P-GLYCOPROTEIN; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; REACTIVE OXYGEN SPECIES;

EID: 84887431990     PISSN: 0315162X     EISSN: 14992752     Source Type: Journal    
DOI: 10.3899/jrheum.130191     Document Type: Article

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