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Volumn 441, Issue 1, 2013, Pages 169-174

Ginsenoside Rg3 improves cardiac mitochondrial population quality: Mimetic exercise training

Author keywords

Aerobic exercise; Cardiac muscle; Ginsenoside Rg3; Mitochondrial quality control

Indexed keywords

BECLIN 1; GINSENOSIDE RG 3; MITOCHONDRIAL DNA; MITOCHONDRIAL TRANSCRIPTION FACTOR A; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF1; TRANSCRIPTION FACTOR NRF2; ADENYLATE KINASE; ANTIOXIDANT; GINSENOSIDE;

EID: 84887431349     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.10.039     Document Type: Article
Times cited : (58)

References (36)
  • 1
    • 0004324213 scopus 로고    scopus 로고
    • Statement on exercise: Benefits and recommendations for physical activity programs for all Americans. A statement for health professionals by the committee on exercise and cardiac rehabilitation of the council on clinical cardiology, American Heart Association
    • G.F. Fletcher, G. Balady, and S.N. Blair Statement on exercise: benefits and recommendations for physical activity programs for all Americans. A statement for health professionals by the committee on exercise and cardiac rehabilitation of the council on clinical cardiology, American Heart Association Circulation 94 1996 857 862
    • (1996) Circulation , vol.94 , pp. 857-862
    • Fletcher, G.F.1    Balady, G.2    Blair, S.N.3
  • 2
    • 33847352937 scopus 로고    scopus 로고
    • Characterization of in vivo tissue redox status, oxygenation, and formation of reactive oxygen species in postischemic myocardium
    • X. Zhu, L. Zuo, and A.J. Cardounel Characterization of in vivo tissue redox status, oxygenation, and formation of reactive oxygen species in postischemic myocardium Antioxid. Redox Signal. 9 2007 447 455
    • (2007) Antioxid. Redox Signal. , vol.9 , pp. 447-455
    • Zhu, X.1    Zuo, L.2    Cardounel, A.J.3
  • 3
    • 27844578184 scopus 로고    scopus 로고
    • Exercise by lifelong voluntary wheel running reduces subsarcolemmal and interfibrillar mitochondrial hydrogen peroxide production in the heart
    • S. Judge, Y.M. Jang, and A. Smith Exercise by lifelong voluntary wheel running reduces subsarcolemmal and interfibrillar mitochondrial hydrogen peroxide production in the heart Am. J. Physiol. Regul. Integr. Comp. Physiol. 289 2005 R1564 R1572
    • (2005) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.289
    • Judge, S.1    Jang, Y.M.2    Smith, A.3
  • 4
    • 34247875918 scopus 로고    scopus 로고
    • Exercise training decreases rat heart mitochondria free radical generation but does not prevent Ca2+-induced dysfunction
    • J.W. Starnes, B.D. Barnes, and M.E. Olsen Exercise training decreases rat heart mitochondria free radical generation but does not prevent Ca2+-induced dysfunction J. Appl. Physiol. 102 2007 1793 1798
    • (2007) J. Appl. Physiol. , vol.102 , pp. 1793-1798
    • Starnes, J.W.1    Barnes, B.D.2    Olsen, M.E.3
  • 5
    • 84866645959 scopus 로고    scopus 로고
    • Impaired transcriptional activity of Nrf2 in age-related myocardial oxidative stress is reversible by moderate exercise training
    • S.S. Gounder, S. Kannan, and D. Devadoss Impaired transcriptional activity of Nrf2 in age-related myocardial oxidative stress is reversible by moderate exercise training PLoS One 7 2012 e45697
    • (2012) PLoS One , vol.7 , pp. 45697
    • Gounder, S.S.1    Kannan, S.2    Devadoss, D.3
  • 6
    • 84871647669 scopus 로고    scopus 로고
    • Exercise training restores cardiac protein quality control in heart failure
    • J.C. Campos, B.B. Queliconi, and P.M. Dourado Exercise training restores cardiac protein quality control in heart failure PLoS One 7 2012 e52764
    • (2012) PLoS One , vol.7 , pp. 52764
    • Campos, J.C.1    Queliconi, B.B.2    Dourado, P.M.3
  • 7
    • 66949139996 scopus 로고    scopus 로고
    • Mitochondrial biogenesis in cardiac pathophysiology
    • S. Rimbaud, A. Garnier, and R. Ventura-Clapier Mitochondrial biogenesis in cardiac pathophysiology Pharmacol. Rep. 61 2009 131 138
    • (2009) Pharmacol. Rep. , vol.61 , pp. 131-138
    • Rimbaud, S.1    Garnier, A.2    Ventura-Clapier, R.3
  • 8
    • 2142758117 scopus 로고    scopus 로고
    • Mitochondrial dynamics in mammals
    • H. Chen, and D.C. Chan Mitochondrial dynamics in mammals Curr. Top. Dev. Biol. 59 2004 119 144
    • (2004) Curr. Top. Dev. Biol. , vol.59 , pp. 119-144
    • Chen, H.1    Chan, D.C.2
  • 9
    • 33745628317 scopus 로고    scopus 로고
    • Proapoptotic BCL-2 family members and mitochondrial dysfunction during ischemia/reperfusion injury, a study employing cardiac HL-1 cells and GFP biosensors
    • N.R. Brady, A. Hamacher-Brady, and R.A. Gottlieb Proapoptotic BCL-2 family members and mitochondrial dysfunction during ischemia/reperfusion injury, a study employing cardiac HL-1 cells and GFP biosensors Biochim. Biophys. Acta 1757 2006 667 678
    • (2006) Biochim. Biophys. Acta , vol.1757 , pp. 667-678
    • Brady, N.R.1    Hamacher-Brady, A.2    Gottlieb, R.A.3
  • 10
    • 70449724857 scopus 로고    scopus 로고
    • Mitochondrial OPA1, apoptosis, and heart failure
    • L. Chen, Q. Gong, and J.P. Stice Mitochondrial OPA1, apoptosis, and heart failure Cardiovasc. Res. 84 2009 91 99
    • (2009) Cardiovasc. Res. , vol.84 , pp. 91-99
    • Chen, L.1    Gong, Q.2    Stice, J.P.3
  • 11
    • 0042339525 scopus 로고    scopus 로고
    • Myocardial hibernation in coronary artery disease
    • D.K. Kalra, and W.A. Zoghbi Myocardial hibernation in coronary artery disease Curr. Atheroscler. Rep. 4 2002 149 155
    • (2002) Curr. Atheroscler. Rep. , vol.4 , pp. 149-155
    • Kalra, D.K.1    Zoghbi, W.A.2
  • 12
    • 84874686751 scopus 로고    scopus 로고
    • Nandrolone attenuates aortic adaptation to exercise in rats
    • M. Sun, W. Shen, and M. Zhong Nandrolone attenuates aortic adaptation to exercise in rats Cardiovasc. Res. 97 2013 686 695
    • (2013) Cardiovasc. Res. , vol.97 , pp. 686-695
    • Sun, M.1    Shen, W.2    Zhong, M.3
  • 13
    • 55549145797 scopus 로고    scopus 로고
    • The anti-fatigue effect of 20(R)-ginsenoside Rg3 in mice by intranasally administration
    • W. Tang, Y. Zhang, and J. Gao The anti-fatigue effect of 20(R)-ginsenoside Rg3 in mice by intranasally administration Biol. Pharm. Bull. 31 2008 2024 2027
    • (2008) Biol. Pharm. Bull. , vol.31 , pp. 2024-2027
    • Tang, W.1    Zhang, Y.2    Gao, J.3
  • 14
    • 77957976228 scopus 로고    scopus 로고
    • Ginsenoside Rg3 inhibits tumor necrosis factor-alpha-induced expression of cell adhesion molecules in human endothelial cells
    • T.T. Hien, N.D. Kim, and H.S. Kim Ginsenoside Rg3 inhibits tumor necrosis factor-alpha-induced expression of cell adhesion molecules in human endothelial cells Pharmazie 65 2010 699 701
    • (2010) Pharmazie , vol.65 , pp. 699-701
    • Hien, T.T.1    Kim, N.D.2    Kim, H.S.3
  • 15
    • 84862830195 scopus 로고    scopus 로고
    • Stereoisomers ginsenosides-20(S)-Rg(3) and -20(R)-Rg(3) differentially induce angiogenesis through peroxisome proliferator-activated receptor-gamma
    • H.H. Kwok, G.L. Guo, and J.K. Lau Stereoisomers ginsenosides-20(S)-Rg(3) and -20(R)-Rg(3) differentially induce angiogenesis through peroxisome proliferator-activated receptor-gamma Biochem. Pharmacol. 83 2012 893 902
    • (2012) Biochem. Pharmacol. , vol.83 , pp. 893-902
    • Kwok, H.H.1    Guo, G.L.2    Lau, J.K.3
  • 16
    • 72249088701 scopus 로고    scopus 로고
    • Cardioprotective effect of the mixture of ginsenoside Rg3 and CK on contractile dysfunction of ischemic heart
    • J.-H. Kim Cardioprotective effect of the mixture of ginsenoside Rg3 and CK on contractile dysfunction of ischemic heart J. Ginseng Res. 31 2007 23 33
    • (2007) J. Ginseng Res. , vol.31 , pp. 23-33
    • Kim, J.-H.1
  • 17
    • 84887498507 scopus 로고    scopus 로고
    • Effect of Rg3 on Swimmer's aerobic capacity
    • D. Zhao, Y. Ban, and H. Zhu Effect of Rg3 on Swimmer's aerobic capacity Sports Sci. Res. 3 2009 72 74
    • (2009) Sports Sci. Res. , vol.3 , pp. 72-74
    • Zhao, D.1    Ban, Y.2    Zhu, H.3
  • 18
    • 84861714642 scopus 로고    scopus 로고
    • Improvements in skeletal muscle strength and cardiac function induced by resveratrol during exercise training contribute to enhanced exercise performance in rats
    • V.W. Dolinsky, K.E. Jones, and R.S. Sidhu Improvements in skeletal muscle strength and cardiac function induced by resveratrol during exercise training contribute to enhanced exercise performance in rats J. Physiol. 590 2012 2783 2799
    • (2012) J. Physiol. , vol.590 , pp. 2783-2799
    • Dolinsky, V.W.1    Jones, K.E.2    Sidhu, R.S.3
  • 19
    • 79955469432 scopus 로고    scopus 로고
    • Mitochondrial dynamic remodeling in strenuous exercise-induced muscle and mitochondrial dysfunction: Regulatory effects of hydroxytyrosol
    • Z. Feng, L. Bai, and J. Yan Mitochondrial dynamic remodeling in strenuous exercise-induced muscle and mitochondrial dysfunction: regulatory effects of hydroxytyrosol Free Radic. Biol. Med. 50 2011 1437 1446
    • (2011) Free Radic. Biol. Med. , vol.50 , pp. 1437-1446
    • Feng, Z.1    Bai, L.2    Yan, J.3
  • 20
    • 84863292345 scopus 로고    scopus 로고
    • Mitochondrial nutrients stimulate performance and mitochondrial biogenesis in exhaustively exercised rats
    • M. Sun, F. Qian, and W. Shen Mitochondrial nutrients stimulate performance and mitochondrial biogenesis in exhaustively exercised rats Scand. J. Med. Sci. Sports 2011
    • (2011) Scand. J. Med. Sci. Sports
    • Sun, M.1    Qian, F.2    Shen, W.3
  • 21
    • 48449094498 scopus 로고    scopus 로고
    • AMPK and PPARdelta agonists are exercise mimetics
    • V.A. Narkar, M. Downes, and R.T. Yu AMPK and PPARdelta agonists are exercise mimetics Cell 134 2008 405 415
    • (2008) Cell , vol.134 , pp. 405-415
    • Narkar, V.A.1    Downes, M.2    Yu, R.T.3
  • 22
    • 80055016811 scopus 로고    scopus 로고
    • Paradoxical effects of streptozotocin-induced diabetes on endothelial dysfunction in stroke-prone spontaneously hypertensive rats
    • M.F. Zhong, W.L. Shen, and J. Wang Paradoxical effects of streptozotocin-induced diabetes on endothelial dysfunction in stroke-prone spontaneously hypertensive rats J. Physiol. 589 2011 5153 5165
    • (2011) J. Physiol. , vol.589 , pp. 5153-5165
    • Zhong, M.F.1    Shen, W.L.2    Wang, J.3
  • 23
    • 84858006645 scopus 로고    scopus 로고
    • Visualization and quantification of cardiac mitochondrial protein clusters with STED microscopy
    • H. Singh, R. Lu, and P.F. Rodriguez Visualization and quantification of cardiac mitochondrial protein clusters with STED microscopy Mitochondrion 12 2012 230 236
    • (2012) Mitochondrion , vol.12 , pp. 230-236
    • Singh, H.1    Lu, R.2    Rodriguez, P.F.3
  • 24
    • 0344443765 scopus 로고    scopus 로고
    • Oxidative alpha-ketoglutarate dehydrogenase inhibition via subtle elevations in monoamine oxidase B levels results in loss of spare respiratory capacity: Implications for Parkinson's disease
    • M.J. Kumar, D.G. Nicholls, and J.K. Andersen Oxidative alpha-ketoglutarate dehydrogenase inhibition via subtle elevations in monoamine oxidase B levels results in loss of spare respiratory capacity: implications for Parkinson's disease J. Biol. Chem. 278 2003 46432 46439
    • (2003) J. Biol. Chem. , vol.278 , pp. 46432-46439
    • Kumar, M.J.1    Nicholls, D.G.2    Andersen, J.K.3
  • 25
    • 0035857493 scopus 로고    scopus 로고
    • Acrolein inhibits respiration in isolated brain mitochondria
    • M.J. Picklo, and T.J. Montine Acrolein inhibits respiration in isolated brain mitochondria Biochim. Biophys. Acta 1535 2001 145 152
    • (2001) Biochim. Biophys. Acta , vol.1535 , pp. 145-152
    • Picklo, M.J.1    Montine, T.J.2
  • 26
    • 46949087413 scopus 로고    scopus 로고
    • Protective effects of R-alpha-lipoic acid and acetyl-l-carnitine in MIN6 and isolated rat islet cells chronically exposed to oleic acid
    • W. Shen, K. Liu, and C. Tian Protective effects of R-alpha-lipoic acid and acetyl-l-carnitine in MIN6 and isolated rat islet cells chronically exposed to oleic acid J. Cell. Biochem. 104 2008 1232 1243
    • (2008) J. Cell. Biochem. , vol.104 , pp. 1232-1243
    • Shen, W.1    Liu, K.2    Tian, C.3
  • 27
    • 84861385983 scopus 로고    scopus 로고
    • Down-regulation of OPA1 alters mouse mitochondrial morphology, PTP function, and cardiac adaptation to pressure overload
    • J. Piquereau, F. Caffin, and M. Novotova Down-regulation of OPA1 alters mouse mitochondrial morphology, PTP function, and cardiac adaptation to pressure overload Cardiovasc. Res. 94 2012 408 417
    • (2012) Cardiovasc. Res. , vol.94 , pp. 408-417
    • Piquereau, J.1    Caffin, F.2    Novotova, M.3
  • 28
    • 77957756428 scopus 로고    scopus 로고
    • Dysfunctional Nrf2-Keap1 redox signaling in skeletal muscle of the sedentary old
    • A. Safdar, J. deBeer, and M.A. Tarnopolsky Dysfunctional Nrf2-Keap1 redox signaling in skeletal muscle of the sedentary old Free Radic. Biol. Med. 49 2010 1487 1493
    • (2010) Free Radic. Biol. Med. , vol.49 , pp. 1487-1493
    • Safdar, A.1    Debeer, J.2    Tarnopolsky, M.A.3
  • 29
    • 84878728657 scopus 로고    scopus 로고
    • The Amelioration of N-acetyl-p-benzoquinone imine toxicity by ginsenoside Rg3: The role of Nrf2-mediated detoxification and Mrp1/Mrp3 transports
    • S.I. Gum, and M.K. Cho The Amelioration of N-acetyl-p-benzoquinone imine toxicity by ginsenoside Rg3: the role of Nrf2-mediated detoxification and Mrp1/Mrp3 transports Oxid. Med. Cell. Longev. 2013 2013 957947
    • (2013) Oxid. Med. Cell. Longev. , vol.2013 , pp. 957947
    • Gum, S.I.1    Cho, M.K.2
  • 30
  • 31
    • 34548848059 scopus 로고    scopus 로고
    • Mitochondrial energetics in the heart in obesity-related diabetes: Direct evidence for increased uncoupled respiration and activation of uncoupling proteins
    • S. Boudina, S. Sena, and H. Theobald Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins Diabetes 56 2007 2457 2466
    • (2007) Diabetes , vol.56 , pp. 2457-2466
    • Boudina, S.1    Sena, S.2    Theobald, H.3
  • 32
    • 77952428203 scopus 로고    scopus 로고
    • Defective DNA replication impairs mitochondrial biogenesis in human failing hearts
    • G. Karamanlidis, L. Nascimben, and G.S. Couper Defective DNA replication impairs mitochondrial biogenesis in human failing hearts Circ. Res. 106 2010 1541 1548
    • (2010) Circ. Res. , vol.106 , pp. 1541-1548
    • Karamanlidis, G.1    Nascimben, L.2    Couper, G.S.3
  • 33
    • 79961021186 scopus 로고    scopus 로고
    • Altered mitochondrial dynamics contributes to endothelial dysfunction in diabetes mellitus
    • S.M. Shenouda, M.E. Widlansky, and K. Chen Altered mitochondrial dynamics contributes to endothelial dysfunction in diabetes mellitus Circulation 124 2011 444 453
    • (2011) Circulation , vol.124 , pp. 444-453
    • Shenouda, S.M.1    Widlansky, M.E.2    Chen, K.3
  • 34
    • 77950238514 scopus 로고    scopus 로고
    • Exercise training improves cardiac function in infarcted rabbits: Involvement of autophagic function and fatty acid utilization
    • C.Y. Chen, H.C. Hsu, and B.C. Lee Exercise training improves cardiac function in infarcted rabbits: involvement of autophagic function and fatty acid utilization Eur. J. Heart Fail. 12 2010 323 330
    • (2010) Eur. J. Heart Fail. , vol.12 , pp. 323-330
    • Chen, C.Y.1    Hsu, H.C.2    Lee, B.C.3
  • 35
    • 84861548814 scopus 로고    scopus 로고
    • Ginsenoside Rg3 reduces lipid accumulation with AMP-activated protein kinase (AMPK) activation in HepG2 cells
    • S. Lee, M.S. Lee, and C.T. Kim Ginsenoside Rg3 reduces lipid accumulation with AMP-activated protein kinase (AMPK) activation in HepG2 cells Int. J. Mol. Sci. 13 2012 5729 5739
    • (2012) Int. J. Mol. Sci. , vol.13 , pp. 5729-5739
    • Lee, S.1    Lee, M.S.2    Kim, C.T.3
  • 36
    • 84871388330 scopus 로고    scopus 로고
    • Oxidative stress mediates chemerin-induced autophagy in endothelial cells
    • W. Shen, C. Tian, and H. Chen Oxidative stress mediates chemerin-induced autophagy in endothelial cells Free Radic. Biol. Med. 55 2013 73 82
    • (2013) Free Radic. Biol. Med. , vol.55 , pp. 73-82
    • Shen, W.1    Tian, C.2    Chen, H.3


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