A directional switch of integrin signalling and a new anti-thrombotic strategy

Nature

Volumn 503, Issue 7474, 2013, Pages 131-135

  Shen, Bo ^a   Zhao, Xiaojuan ^a   O'Brien, Kelly A ^a   Stojanovic Terpo, Aleksandra ^a   Delaney, M Keegan ^a   Kim, Kyungho ^a   Cho, Jaehyung ^a   Lam, Stephen C T ^a   Du, Xiaoping ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; BETA3 INTEGRIN; TALIN;

DRUG; SIGNALING;

ANIMAL CELL; ARTERY THROMBOSIS; ARTICLE; BLEEDING; BLOOD CLOT RETRACTION; BLOOD CLOTTING; CONTROLLED STUDY; CYTOPLASM; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; SIGNAL TRANSDUCTION; THROMBOCYTE; THROMBOCYTE AGGREGATION;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; ANTITHROMBINS; BINDING SITES; BLEEDING TIME; CELL POLARITY; CYTOPLASM; GTP-BINDING PROTEIN ALPHA SUBUNITS, G12-G13; HEMORRHAGE; HUMANS; INTEGRIN BETA3; INTEGRINS; MALE; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION; TALIN; THROMBOSIS;

EID: 84887408822     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature12613     Document Type: Article

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