메뉴 건너뛰기




Volumn 62, Issue , 2014, Pages 354-364

Treatment with afobazole at delayed time points following ischemic stroke improves long-term functional and histological outcomes

Author keywords

Afobazole; Behavior; Ischemic stroke; Middle cerebral artery occlusion; Neuroprotection; Oligodendroglia; Sigma receptor

Indexed keywords

AFOBAZOLE; ANXIOLYTIC AGENT; BD 1063; RECEPTOR BLOCKING AGENT; SM 21; UNCLASSIFIED DRUG;

EID: 84887379919     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2013.10.011     Document Type: Article
Times cited : (26)

References (35)
  • 1
    • 33646876375 scopus 로고    scopus 로고
    • Sigma receptor activation reduces infarct size at 24hours after permanent middle cerebral artery occlusion in rats
    • Ajmo C.T., Vernon D.O., Collier L., Pennypacker K.R., Cuevas J. Sigma receptor activation reduces infarct size at 24hours after permanent middle cerebral artery occlusion in rats. Curr. Neurovasc. Res. 2006, 3:89-98.
    • (2006) Curr. Neurovasc. Res. , vol.3 , pp. 89-98
    • Ajmo, C.T.1    Vernon, D.O.2    Collier, L.3    Pennypacker, K.R.4    Cuevas, J.5
  • 5
    • 0032539034 scopus 로고    scopus 로고
    • Early assessment of motor dysfunctions aids in successful occlusion of the middle cerebral artery
    • Borlongan C.V., Hida H., Nishino H. Early assessment of motor dysfunctions aids in successful occlusion of the middle cerebral artery. Neuroreport 1998, 9:3615-3621.
    • (1998) Neuroreport , vol.9 , pp. 3615-3621
    • Borlongan, C.V.1    Hida, H.2    Nishino, H.3
  • 6
    • 0037040519 scopus 로고    scopus 로고
    • Neurodegeneration in the rat hippocampus and striatum after middle cerebral artery occlusion
    • Butler T.L., Kassed C.A., Sanberg P.R., Willing A.E., Pennypacker K.R. Neurodegeneration in the rat hippocampus and striatum after middle cerebral artery occlusion. Brain Res. 2002, 929:252-260.
    • (2002) Brain Res. , vol.929 , pp. 252-260
    • Butler, T.L.1    Kassed, C.A.2    Sanberg, P.R.3    Willing, A.E.4    Pennypacker, K.R.5
  • 7
    • 80053149971 scopus 로고    scopus 로고
    • Afobazole modulates neuronal response to ischemia and acidosis via activation of sigma-1 receptors
    • Cuevas J., Behensky A., Deng W., Katnik C. Afobazole modulates neuronal response to ischemia and acidosis via activation of sigma-1 receptors. J. Pharmacol. Exp. Ther. 2011, 339:152-160.
    • (2011) J. Pharmacol. Exp. Ther. , vol.339 , pp. 152-160
    • Cuevas, J.1    Behensky, A.2    Deng, W.3    Katnik, C.4
  • 8
    • 80053136199 scopus 로고    scopus 로고
    • Afobazole modulates microglial function via activation of both sigma-1 and sigma-2 receptors
    • Cuevas J., Rodriguez A., Behensky A., Katnik C. Afobazole modulates microglial function via activation of both sigma-1 and sigma-2 receptors. J. Pharmacol. Exp. Ther. 2011, 339:161-172.
    • (2011) J. Pharmacol. Exp. Ther. , vol.339 , pp. 161-172
    • Cuevas, J.1    Rodriguez, A.2    Behensky, A.3    Katnik, C.4
  • 11
    • 29244455020 scopus 로고    scopus 로고
    • Talampanel improves the functional deficit after transient focal cerebral ischemia in rats. A 30-day follow up study
    • Erdo F., Berzsenyi P., Nemet L., Andrasi F. Talampanel improves the functional deficit after transient focal cerebral ischemia in rats. A 30-day follow up study. Brain Res. Bull. 2006, 68:269-276.
    • (2006) Brain Res. Bull. , vol.68 , pp. 269-276
    • Erdo, F.1    Berzsenyi, P.2    Nemet, L.3    Andrasi, F.4
  • 13
    • 0034491018 scopus 로고    scopus 로고
    • Pharmacological identification of SM-21, the novel sigma(2) antagonist
    • Ghelardini C., Galeotti N., Bartolini A. Pharmacological identification of SM-21, the novel sigma(2) antagonist. Pharmacol. Biochem. Behav. 2000, 67:659-662.
    • (2000) Pharmacol. Biochem. Behav. , vol.67 , pp. 659-662
    • Ghelardini, C.1    Galeotti, N.2    Bartolini, A.3
  • 14
    • 1842861541 scopus 로고    scopus 로고
    • Comparative electroencephalographic evaluation of anxiolytics afobazol and diazepam in MR and MNRA inbred rats with different anxiety levels
    • Kozhechkin S.N. Comparative electroencephalographic evaluation of anxiolytics afobazol and diazepam in MR and MNRA inbred rats with different anxiety levels. Eksp. Klin. Farmakol. 2003, 66:38-41.
    • (2003) Eksp. Klin. Farmakol. , vol.66 , pp. 38-41
    • Kozhechkin, S.N.1
  • 17
    • 84868198165 scopus 로고    scopus 로고
    • White matter lesion severity in mild acute ischemic stroke patients and functional outcome after 1year
    • Leonards C.O., Ipsen N., Malzahn U., Fiebach J.B., Endres M., Ebinger M. White matter lesion severity in mild acute ischemic stroke patients and functional outcome after 1year. Stroke 2012, 43:3046-3051.
    • (2012) Stroke , vol.43 , pp. 3046-3051
    • Leonards, C.O.1    Ipsen, N.2    Malzahn, U.3    Fiebach, J.B.4    Endres, M.5    Ebinger, M.6
  • 19
    • 0035815645 scopus 로고    scopus 로고
    • (+/-)-SM 21 attenuates the convulsive and locomotor stimulatory effects of cocaine in mice
    • Matsumoto R.R., Mack A.L. (+/-)-SM 21 attenuates the convulsive and locomotor stimulatory effects of cocaine in mice. Eur. J. Pharmacol. 2001, 417:R1-R2.
    • (2001) Eur. J. Pharmacol. , vol.417
    • Matsumoto, R.R.1    Mack, A.L.2
  • 20
    • 0029053594 scopus 로고
    • Characterization of two novel sigma receptor ligands: antidystonic effects in rats suggest sigma receptor antagonism
    • Matsumoto R.R., Bowen W.D., Tom M.A., Vo V.N., Truong D.D., De Costa B.R. Characterization of two novel sigma receptor ligands: antidystonic effects in rats suggest sigma receptor antagonism. Eur. J. Pharmacol. 1995, 280:301-310.
    • (1995) Eur. J. Pharmacol. , vol.280 , pp. 301-310
    • Matsumoto, R.R.1    Bowen, W.D.2    Tom, M.A.3    Vo, V.N.4    Truong, D.D.5    De Costa, B.R.6
  • 21
    • 0035843786 scopus 로고    scopus 로고
    • Conformationally restricted analogs of BD1008 and an antisense oligodeoxynucleotide targeting sigma1 receptors produce anti-cocaine effects in mice
    • Matsumoto R.R., McCracken K.A., Friedman M.J., Pouw B., De Costa B.R., Bowen W.D. Conformationally restricted analogs of BD1008 and an antisense oligodeoxynucleotide targeting sigma1 receptors produce anti-cocaine effects in mice. Eur. J. Pharmacol. 2001, 419:163-174.
    • (2001) Eur. J. Pharmacol. , vol.419 , pp. 163-174
    • Matsumoto, R.R.1    McCracken, K.A.2    Friedman, M.J.3    Pouw, B.4    De Costa, B.R.5    Bowen, W.D.6
  • 22
    • 33847042772 scopus 로고    scopus 로고
    • Effects of UMB24 and (+/-)-SM 21, putative sigma2-preferring antagonists, on behavioral toxic and stimulant effects of cocaine in mice
    • Matsumoto R.R., Pouw B., Mack A.L., Daniels A., Coop A. Effects of UMB24 and (+/-)-SM 21, putative sigma2-preferring antagonists, on behavioral toxic and stimulant effects of cocaine in mice. Pharmacol. Biochem. Behav. 2007, 86:86-91.
    • (2007) Pharmacol. Biochem. Behav. , vol.86 , pp. 86-91
    • Matsumoto, R.R.1    Pouw, B.2    Mack, A.L.3    Daniels, A.4    Coop, A.5
  • 23
    • 0033555570 scopus 로고    scopus 로고
    • Novel sigma receptor ligands attenuate the locomotor stimulatory effects of cocaine
    • McCracken K.A., Bowen W.D., Matsumoto R.R. Novel sigma receptor ligands attenuate the locomotor stimulatory effects of cocaine. Eur. J. Pharmacol. 1999, 365:35-38.
    • (1999) Eur. J. Pharmacol. , vol.365 , pp. 35-38
    • McCracken, K.A.1    Bowen, W.D.2    Matsumoto, R.R.3
  • 24
  • 25
    • 0018591165 scopus 로고
    • A method for the routine assessment of fore- and hindlimb grip strength of rats and mice
    • Meyer O.A., Tilson H.A., Byrd W.C., Riley M.T. A method for the routine assessment of fore- and hindlimb grip strength of rats and mice. Neurobehav. Toxicol. 1979, 1:233-236.
    • (1979) Neurobehav. Toxicol. , vol.1 , pp. 233-236
    • Meyer, O.A.1    Tilson, H.A.2    Byrd, W.C.3    Riley, M.T.4
  • 26
    • 0034671355 scopus 로고    scopus 로고
    • Neurological sequelae and long-term behavioural assessment of rats with transient middle cerebral artery occlusion
    • Modo M., Stroemer R.P., Tang E., Veizovic T., Sowniski P., Hodges H. Neurological sequelae and long-term behavioural assessment of rats with transient middle cerebral artery occlusion. J. Neurosci. Methods 2000, 104:99-109.
    • (2000) J. Neurosci. Methods , vol.104 , pp. 99-109
    • Modo, M.1    Stroemer, R.P.2    Tang, E.3    Veizovic, T.4    Sowniski, P.5    Hodges, H.6
  • 28
    • 84866487963 scopus 로고    scopus 로고
    • Effects of the sigma-1 receptor agonist 1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)-piperazine dihydro-chloride on inflammation after stroke
    • Ruscher K., Inacio A.R., Valind K., Rowshan Ravan A., Kuric E., Wieloch T. Effects of the sigma-1 receptor agonist 1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)-piperazine dihydro-chloride on inflammation after stroke. PLoS One 2012, 7:e45118.
    • (2012) PLoS One , vol.7
    • Ruscher, K.1    Inacio, A.R.2    Valind, K.3    Rowshan Ravan, A.4    Kuric, E.5    Wieloch, T.6
  • 29
    • 33744515839 scopus 로고    scopus 로고
    • An improved post-operative care protocol allows detection of long-term functional deficits following MCAo surgery in rats
    • Ryan C.L., Doucette T.A., Gill D.A., Langdon K.D., Liu Y., Perry M.A., Tasker R.A. An improved post-operative care protocol allows detection of long-term functional deficits following MCAo surgery in rats. J. Neurosci. Methods 2006, 154:30-37.
    • (2006) J. Neurosci. Methods , vol.154 , pp. 30-37
    • Ryan, C.L.1    Doucette, T.A.2    Gill, D.A.3    Langdon, K.D.4    Liu, Y.5    Perry, M.A.6    Tasker, R.A.7
  • 30
    • 50649115279 scopus 로고    scopus 로고
    • Neuroprotective effect of afobazole on rats with bilateral local photothrombosis of vessels in the prefrontal cortex
    • Seredenin S.B., Romanova G.A., Shakova F.M. Neuroprotective effect of afobazole on rats with bilateral local photothrombosis of vessels in the prefrontal cortex. Bull. Exp. Biol. Med. 2008, 145:207-209.
    • (2008) Bull. Exp. Biol. Med. , vol.145 , pp. 207-209
    • Seredenin, S.B.1    Romanova, G.A.2    Shakova, F.M.3
  • 31
    • 0029847364 scopus 로고    scopus 로고
    • PPBP [4-phenyl-1-(4-phenylbutyl) piperidine] decreases brain injury after transient focal ischemia in rats
    • Takahashi H., Kirsch J.R., Hashimoto K., London E.D., Koehler R.C., Traystman R.J. PPBP [4-phenyl-1-(4-phenylbutyl) piperidine] decreases brain injury after transient focal ischemia in rats. Stroke 1996, 27:2120-2123.
    • (1996) Stroke , vol.27 , pp. 2120-2123
    • Takahashi, H.1    Kirsch, J.R.2    Hashimoto, K.3    London, E.D.4    Koehler, R.C.5    Traystman, R.J.6
  • 33
    • 84859059514 scopus 로고    scopus 로고
    • World Health Organization, Geneva, Switzerland
    • WHO World Health Statistics 2011 2011, 170. World Health Organization, Geneva, Switzerland.
    • (2011) WHO World Health Statistics 2011 , pp. 170


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.