Complement C3 depletion links to the expansion of regulatory T cells and compromises T-cell immunity in human abdominal sepsis: A prospective pilot study

Journal of Critical Care

Volumn 28, Issue 6, 2013, Pages 1032-1038

  Yuan, Yujie ^a   Yan, Dongsheng ^b   Han, Gang ^c   Gu, Guosheng ^b   Ren, Jianan ^b  

^a THE FIRST AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

^b MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^c THE SECOND HOSPITAL OF JILIN UNIVERSITY   (China)

Author keywords

Adaptive immunity; Complement; Regulatory T cells; Sepsis

Indexed keywords

COMPLEMENT COMPONENT C3;

ADULT; ARTICLE; CD4 CD8 RATIO; CELL EXPANSION; CELLULAR IMMUNITY; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; HOSPITAL COST; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOSUPPRESSIVE TREATMENT; LENGTH OF STAY; LYMPHOCYTE COUNT; LYMPHOCYTE FUNCTION; MAJOR CLINICAL STUDY; MALE; MOLECULAR DYNAMICS; MORTALITY; OUTCOME ASSESSMENT; PILOT STUDY; POSTOPERATIVE COMPLICATION; PROSPECTIVE STUDY; PROTEIN DEPLETION; PROTEIN DETERMINATION; PROTEIN FUNCTION; REGULATORY T LYMPHOCYTE; SEPSIS;

ADAPTIVE IMMUNITY; COMPLEMENT; REGULATORY T CELLS; SEPSIS;

ABDOMEN; ADAPTIVE IMMUNITY; ADULT; BACTERIAL LOAD; COMPLEMENT C3; FEMALE; HOSPITAL COSTS; HUMANS; INTENSIVE CARE UNITS; LENGTH OF STAY; MALE; PILOT PROJECTS; POSTOPERATIVE COMPLICATIONS; PROSPECTIVE STUDIES; SEPSIS; T-LYMPHOCYTES, REGULATORY; TIME FACTORS;

EID: 84887359215     PISSN: 08839441     EISSN: 15578615     Source Type: Journal    
DOI: 10.1016/j.jcrc.2013.09.007     Document Type: Article

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