Exogenous C3 protein enhances the adaptive immune response to polymicrobial sepsis through down-regulation of regulatory T cells

International Immunopharmacology

Volumn 12, Issue 1, 2012, Pages 271-277

  Yuan, Yujie ^a   Ren, Jianan ^a   Cao, Shougen ^a   Zhang, Weiwei ^a   Li, Jieshou ^a  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

Author keywords

Adaptive immune; Complement C3; NF B; Sepsis; T regulatory cells; Th cells

Indexed keywords

COMPLEMENT COMPONENT C3; CYTOKINE; HUMAN PURIFIED C3 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOLOGIC AGENT; INTERLEUKIN 10; TRANSCRIPTION FACTOR FOXP3; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CELL ACTIVATION; CONTROLLED STUDY; DOWN REGULATION; DRUG RESPONSE; FEMALE; MOUSE; NONHUMAN; PERITONITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SEPSIS; SURVIVAL RATE; TH1 CELL; TH17 CELL; TH2 CELL;

ADAPTIVE IMMUNITY; ANIMALS; COMPLEMENT C3; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; INTERLEUKIN-10; MICE; MICE, INBRED C57BL; NF-KAPPA B; RNA, MESSENGER; SEPSIS; T-LYMPHOCYTE SUBSETS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84856120141     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2011.11.022     Document Type: Article

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