Modeling nigrostriatal degeneration in organotypic cultures, a new ex vivo model of Parkinson's disease

Neuroscience

Volumn 256, Issue , 2014, Pages 10-22

  Daviaud, N ^a,b   Garbayo, E ^a,b,c   Lautram, N ^a,b   Franconi, F ^a   Lemaire, L ^a,b   Perez Pinzon, M ^d   Montero Menei, C N ^a,b  

^a LUNAM   (France)

^b UNIVERSITÉ D'ANGERS   (France)

^c UNIVERSITY OF NAVARRA   (Spain)

^d UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Diffusion tensor imaging; Dopamine; Mass spectrometry; MRI; Nigrostriatal organotypic slices; Parkinson's disease

Indexed keywords

DOPAMINE; TYROSINE 3 MONOOXYGENASE; ENOLASE;

ANATOMIC MODEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL INTERACTION; CELL SURVIVAL; DIFFUSION TENSOR IMAGING; DISEASE MODEL; EX VIVO STUDY; FRACTIONAL ANISOTROPY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MASS SPECTROMETRY; MEDIAL FOREBRAIN BUNDLE; NERVE FIBER DEGENERATION; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PARKINSON DISEASE; PRIORITY JOURNAL; RAT; STRIATONIGRAL DEGENERATION; SUBSTANTIA NIGRA; ANIMAL; CORPUS STRIATUM; DEGENERATIVE DISEASE; FEMALE; HUMAN; METABOLISM; NERVE TRACT; NEWBORN; ORGAN CULTURE TECHNIQUE; PATHOLOGY; PREGNANCY; SPRAGUE DAWLEY RAT;

ANIMALS; ANIMALS, NEWBORN; CORPUS STRIATUM; DIFFUSION TENSOR IMAGING; DISEASE MODELS, ANIMAL; DOPAMINE; FEMALE; HUMANS; MASS SPECTROMETRY; MEDIAL FOREBRAIN BUNDLE; NEURAL PATHWAYS; NEURODEGENERATIVE DISEASES; ORGAN CULTURE TECHNIQUES; PHOSPHOPYRUVATE HYDRATASE; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; SUBSTANTIA NIGRA; TYROSINE 3-MONOOXYGENASE;

EID: 84887348727     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2013.10.021     Document Type: Article

References (48)

1. Alberio T., Lopiano L., Fasano M. Cellular models to investigate biochemical pathways in Parkinson's disease. FEBS J 2012, 279:1146-1155.
2. Beirowski B., Adalbert R., Wagner D., Grumme D.S., Addicks K., Ribchester R.R., Coleman M.P. The progressive nature of Wallerian degeneration in wild-type and slow Wallerian degeneration (WldS) nerves. BMC Neurosci 2005, 6:6.
3. Blandini F. Neural and immune mechanisms in the pathogenesis of Parkinson's disease. J Neuroimmune Pharmacol 2013, 8:189-201.
4. Cavaliere F., Vicente E.S., Matute C. An organotypic culture model to study nigro-striatal degeneration. J Neurosci Methods 2010, 188:205-212.
5. Daviaud N., Garbayo E., Schiller P.C., Perez-Pinzon M., Montero-Menei C.N. Organotypic cultures as tools for optimization of central nervous system cell therapies. Exp Neurol 2013, 248:429-440.
6. Daviaud N, Garbayo E, Sindji L, Serrano AM, Perez-Pinzon M, Schiller PC, Montero-Menei CN (2011) Pharmacologically active microcarriers carrying stem cells for tissue engineering in an organotypic model of neurodegenerative disorders, personal communication. Tissue Engineering & Regenerative Medicine International Society (TERMIS).
7. Dawson T.M., Ko H.S., Dawson V.L. Genetic animal models of Parkinson's disease. Neuron 2010, 66:646-661.
8. Delli Pizzi S., Rossi C., Di Matteo V., Esposito E., Guarnieri S., Mariggio M.A., Franciotti R., Caulo M., Thomas A., Onofrj M., Tartaro A., Bonanni L. Morphological and metabolic changes in the nigro-striatal pathway of synthetic proteasome inhibitor (PSI)-treated rats: a MRI and MRS study. PLoS One 2013, 8:e56501.
9. Diekmann S., Nitsch R., Ohm T.G. The organotypic entorhinal-hippocampal complex slice culture of adolescent rats. A model to study transcellular changes in a circuit particularly vulnerable in neurodegenerative disorders. J Neural Transm Suppl 1994, 44:61-71.
10. Ecker D., Unrath A., Kassubek J., Sabolek M. Dopamine agonists and their risk to induce psychotic episodes in Parkinson's disease: a case-control study. BMC Neurol 2009, 9:23.
11. Fernandez-Bueno I., Fernandez-Sanchez L., Gayoso M.J., Garcia-Gutierrez M.T., Pastor J.C., Cuenca N. Time course modifications in organotypic culture of human neuroretina. Exp Eye Res 2012, 104:26-38.
12. Finley M., Fairman D., Liu D., Li P., Wood A., Cho S. Functional validation of adult hippocampal organotypic cultures as an in vitro model of brain injury. Brain Res 2004, 1001:125-132.
13. Flint J.J., Hansen B., Fey M., Schmidig D., King M.A., Vestergaard-Poulsen P., Blackband S.J. Cellular-level diffusion tensor microscopy and fiber tracking in mammalian nervous tissue with direct histological correlation. Neuroimage 2010, 52:556-561.
14. Gahwiler B.H. Organotypic monolayer cultures of nervous tissue. J Neurosci Methods 1981, 4:329-342.
15. Ganesana M., Erlichman J.S., Andreescu S. Real-time monitoring of superoxide accumulation and antioxidant activity in a brain slice model using an electrochemical cytochrome c biosensor. Free Radic Biol Med 2012, 53:2240-2249.
16. Garzon-Muvdi T., Quinones-Hinojosa A. Neural stem cell niches and homing: recruitment and integration into functional tissues. ILAR J 2009, 51:3-23.
17. Gazewood J.D., Richards D.R., Clebak K. Parkinson disease: an update. Am Fam Physician 2013, 87:267-273.
18. Hauser R.A. Levodopa: past, present, and future. Eur Neurol 2009, 62:1-8.
19. Ishihara M., Mochizuki-Oda N., Iwatsuki K., Kishima H., Iwamoto Y., Ohnishi Y., Umegaki M., Yoshimine T. A new three-dimensional axonal outgrowth assay for central nervous system regeneration. J Neurosci Methods 2011, 198:181-186.
20. Jackson-Lewis V., Blesa J., Przedborski S. Animal models of Parkinson's disease. Parkinsonism Relat Disord 2012, 18(Suppl. 1):S183-S185.
21. Jaeger C., Gonzalo Ruiz A., Llinas R. Organotypic slice cultures of dopaminergic neurons of substantia nigra. Brain Res Bull 1989, 22:981-991.
22. Kearns S.M., Scheffler B., Goetz A.K., Lin D.D., Baker H.D., Roper S.N., Mandel R.J., Steindler D.A. A method for a more complete in vitro Parkinson's model: slice culture bioassay for modeling maintenance and repair of the nigrostriatal circuit. J Neurosci Methods 2006, 157:1-9.
23. Kordower J.H., Olanow C.W., Dodiya H.B., Chu Y., Beach T.G., Adler C.H., Halliday G.M., Bartus R.T. Disease duration and the integrity of the nigrostriatal system in Parkinson's disease. Brain 2013, 136(Pt 8):2419-2431.
24. Kim H., Kim E., Park M., Lee E., Namkoong K. Organotypic hippocampal slice culture from the adult mouse brain: a versatile tool for translational neuropsychopharmacology. Prog Neuropsychopharmacol Biol Psychiatry 2013, 41:36-43.
25. Krabbe C., Courtois E., Jensen P., Jorgensen J.R., Zimmer J., Martinez-Serrano A., Meyer M. Enhanced dopaminergic differentiation of human neural stem cells by synergistic effect of Bcl-xL and reduced oxygen tension. J Neurochem 2009, 110:1908-1920.
26. Lees A.J., Hardy J., Revesz T. Parkinson's disease. Lancet 2009, 373:2055-2066.
27. Lindvall O. Developing dopaminergic cell therapy for Parkinson's disease-give up or move forward?. Mov Disord 2013, 28:268-273.
28. Cavaliere F, Matute C (2011) Utility of Organotypic Slices in Parkinson's Disease Research, Towards New Therapies for Parkinson's Disease. David Finkelstein (Ed.), ISBN: 978-953-307-463-4, InTech, http://dx.oi.org/10.5772/16902.
29. Ostergaard K., Schou J.P., Zimmer J. Rat ventral mesencephalon grown as organotypic slice cultures and co-cultured with striatum, hippocampus, and cerebellum. Exp Brain Res 1990, 82:547-565.
30. Parkinson J. An essay on the shaking palsy. J Neuropsychiatry Clin Neurosci 1817, 14:223-236. (discussion 222).
31. Petridou N., Plenz D., Silva A.C., Loew M., Bodurka J., Bandettini P.A. Direct magnetic resonance detection of neuronal electrical activity. Proc Natl Acad Sci U S A 2006, 103:16015-16020.
32. Plenz D., Aertsen A. Neural dynamics in cortex-striatum co-cultures - I. Anatomy and electrophysiology of neuronal cell types. Neuroscience 1996, 70:861-891.
33. Plenz D., Aertsen A. Neural dynamics in cortex-striatum co-cultures - II. Spatiotemporal characteristics of neuronal activity. Neuroscience 1996, 70:893-924.
34. Plenz D., Kitai S.T. Organotypic cortex-striatum-mesencephalon cultures: the nigrostriatal pathway. Neurosci Lett 1996, 209:177-180.
35. Poewe W., Mahlknecht P., Jankovic J. Emerging therapies for Parkinson's disease. Curr Opin Neurol 2012, 25:448-459.
36. Schober A. Classic toxin-induced animal models of Parkinson's disease: 6-OHDA and MPTP. Cell Tissue Res 2004, 318:215-224.
37. Shepherd T.M., Ozarslan E., King M.A., Mareci T.H., Blackband S.J. Structural insights from high-resolution diffusion tensor imaging and tractography of the isolated rat hippocampus. Neuroimage 2006, 32:1499-1509.
38. Shepherd T.M., Scheffler B., King M.A., Stanisz G.J., Steindler D.A., Blackband S.J. MR microscopy of rat hippocampal slice cultures: a novel model for studying cellular processes and chronic perturbations to tissue microstructure. Neuroimage 2006, 30:780-786.
39. Shepherd T.M., Thelwall P.E., Blackband S.J., Pike B.R., Hayes R.L., Wirth E.D. Diffusion magnetic resonance imaging study of a rat hippocampal slice model for acute brain injury. J Cereb Blood Flow Metab 2003, 23:1461-1470.
40. Spillantini M.G., Schmidt M.L., Lee V.M., Trojanowski J.Q., Jakes R., Goedert M. Alpha-synuclein in Lewy bodies. Nature 1997, 388:839-840.
41. Stahl K., Skare O., Torp R. Organotypic cultures as a model of Parkinson s disease. A twist to an old model. Sci World J 2009, 9:811-821.
42. Stoppini L., Buchs P.A., Muller D. A simple method for organotypic cultures of nervous tissue. J Neurosci Methods 1991, 37:173-182.
43. Su T., Paradiso B., Long Y.S., Liao W.P., Simonato M. Evaluation of cell damage in organotypic hippocampal slice culture from adult mouse: a potential model system to study neuroprotection. Brain Res 2011, 1385:68-76.
44. Tieu K. A guide to neurotoxic animal models of Parkinson's disease. Cold Spring Harb Perspect Med 2011, 1:a009316.
45. Ullrich C., Daschil N., Humpel C. Organotypic vibrosections: novel whole sagittal brain cultures. J Neurosci Methods 2011, 201:131-141.
46. Volles M.J., Lansbury P.T. Zeroing in on the pathogenic form of alpha-synuclein and its mechanism of neurotoxicity in Parkinson's disease. Biochemistry 2003, 42:7871-7878.
47. Yoshikawa K., Nakata Y., Yamada K., Nakagawa M. Early pathological changes in the parkinsonian brain demonstrated by diffusion tensor MRI. J Neurol Neurosurg Psychiatry 2004, 75:481-484.
48. Ziemka-Nalecz M., Stanaszek L., Zalewska T. Oxygen-glucose deprivation promotes gliogenesis and microglia activation in organotypic hippocampal slice culture: involvement of metalloproteinases. Acta Neurobiol Exp (Wars) 2013, 73:130-142.