메뉴 건너뛰기




Volumn 28, Issue 3, 2013, Pages 268-273

Developing dopaminergic cell therapy for Parkinson's disease-give up or move forward?

Author keywords

Dopaminergic neurons; Neural grafts; Parkinson's disease; Stem cells; Transplantation

Indexed keywords

DOPAMINE;

EID: 84875497155     PISSN: 08853185     EISSN: 15318257     Source Type: Journal    
DOI: 10.1002/mds.25378     Document Type: Note
Times cited : (66)

References (51)
  • 1
    • 0021988433 scopus 로고
    • Transplantation of adrenal medullary tissue to striatum in parkinsonism. First clinical trials
    • Backlund EO, Granberg PO, Hamberger B, et al. Transplantation of adrenal medullary tissue to striatum in parkinsonism. First clinical trials. J Neurosurg 1985;62:169-173.
    • (1985) J Neurosurg , vol.62 , pp. 169-173
    • Backlund, E.O.1    Granberg, P.O.2    Hamberger, B.3
  • 2
    • 0023628653 scopus 로고
    • Transplantation in Parkinson's disease: two cases of adrenal medullary grafts to the putamen
    • Lindvall O, Backlund EO, Farde L, et al. Transplantation in Parkinson's disease: two cases of adrenal medullary grafts to the putamen. Ann Neurol 1987;22:457-468.
    • (1987) Ann Neurol , vol.22 , pp. 457-468
    • Lindvall, O.1    Backlund, E.O.2    Farde, L.3
  • 3
    • 0033934144 scopus 로고    scopus 로고
    • Bilateral caudate and putamen grafts of embryonic mesencephalic tissue treated with lazaroids in Parkinson's disease
    • Brundin P, Pogarell O, Hagell P, et al. Bilateral caudate and putamen grafts of embryonic mesencephalic tissue treated with lazaroids in Parkinson's disease. Brain 2000;123:1380-1390.
    • (2000) Brain , vol.123 , pp. 1380-1390
    • Brundin, P.1    Pogarell, O.2    Hagell, P.3
  • 4
    • 0029160456 scopus 로고
    • Bilateral fetal nigral transplantation into the postcommissural putamen in Parkinson's disease
    • Freeman TB, Olanow CW, Hauser RA, et al. Bilateral fetal nigral transplantation into the postcommissural putamen in Parkinson's disease. Ann Neurol 1995;38:379-388.
    • (1995) Ann Neurol , vol.38 , pp. 379-388
    • Freeman, T.B.1    Olanow, C.W.2    Hauser, R.A.3
  • 5
    • 0032692348 scopus 로고    scopus 로고
    • Sequential bilateral transplantation in Parkinson's disease: effects of the second graft
    • Hagell P, Schrag A, Piccini P, et al. Sequential bilateral transplantation in Parkinson's disease: effects of the second graft. Brain 1999;122 1121-1132.
    • (1999) Brain , vol.122 , pp. 1121-1132
    • Hagell, P.1    Schrag, A.2    Piccini, P.3
  • 6
    • 0033053030 scopus 로고    scopus 로고
    • Long-term evaluation of bilateral fetal nigral transplantation in Parkinson disease
    • Hauser RA, Freeman TB, Snow BJ, et al. Long-term evaluation of bilateral fetal nigral transplantation in Parkinson disease. Arch Neurol 1999;56:179-187.
    • (1999) Arch Neurol , vol.56 , pp. 179-187
    • Hauser, R.A.1    Freeman, T.B.2    Snow, B.J.3
  • 7
    • 0025058215 scopus 로고
    • Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's disease
    • Lindvall O, Brundin P, Widner H, et al. Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's disease. Science 1990;247:574-577.
    • (1990) Science , vol.247 , pp. 574-577
    • Lindvall, O.1    Brundin, P.2    Widner, H.3
  • 8
    • 0027977759 scopus 로고
    • Evidence for long-term survival and function of dopaminergic grafts in progressive Parkinson's disease
    • Lindvall O, Sawle G, Widner H, et al. Evidence for long-term survival and function of dopaminergic grafts in progressive Parkinson's disease. Ann Neurol 1994;35:172-180.
    • (1994) Ann Neurol , vol.35 , pp. 172-180
    • Lindvall, O.1    Sawle, G.2    Widner, H.3
  • 9
    • 0026584525 scopus 로고
    • Transplantation of fetal dopamine neurons in Parkinson's disease: one-year clinical and neurophysiological observations in two patients with putaminal implants
    • Lindvall O, Widner H, Rehncrona S, et al. Transplantation of fetal dopamine neurons in Parkinson's disease: one-year clinical and neurophysiological observations in two patients with putaminal implants. Ann Neurol 1992;31:155-165.
    • (1992) Ann Neurol , vol.31 , pp. 155-165
    • Lindvall, O.1    Widner, H.2    Rehncrona, S.3
  • 10
    • 0028360518 scopus 로고
    • Bilateral motor improvement and alteration of L-dopa effect in two patients with Parkinson's disease following intrastriatal transplantation of foetal ventral mesencephalon
    • Peschanski M, Defer G, N'Guyen JP, et al. Bilateral motor improvement and alteration of L-dopa effect in two patients with Parkinson's disease following intrastriatal transplantation of foetal ventral mesencephalon. Brain 1994;117:487-499.
    • (1994) Brain , vol.117 , pp. 487-499
    • Peschanski, M.1    Defer, G.2    N'Guyen, J.P.3
  • 11
    • 0028991533 scopus 로고
    • Clinical correlates of [18F]fluorodopa uptake in five grafted parkinsonian patients
    • Remy P, Samson Y, Hantraye P, et al. Clinical correlates of [18F]fluorodopa uptake in five grafted parkinsonian patients. Ann Neurol 1995;38:580-588.
    • (1995) Ann Neurol , vol.38 , pp. 580-588
    • Remy, P.1    Samson, Y.2    Hantraye, P.3
  • 12
    • 0026533881 scopus 로고
    • Transplantation of fetal dopamine neurons in Parkinson's disease: PET [18F]6-L-fluorodopa studies in two patients with putaminal implants
    • Sawle GV, Bloomfield PM, Bjorklund A, et al. Transplantation of fetal dopamine neurons in Parkinson's disease: PET [18F]6-L-fluorodopa studies in two patients with putaminal implants. Ann Neurol 1992;31:166-173.
    • (1992) Ann Neurol , vol.31 , pp. 166-173
    • Sawle, G.V.1    Bloomfield, P.M.2    Bjorklund, A.3
  • 13
    • 0030834093 scopus 로고    scopus 로고
    • Short- and long-term survival and function of unilateral intrastriatal dopaminergic grafts in Parkinson's disease
    • Wenning GK, Odin P, Morrish P, et al. Short- and long-term survival and function of unilateral intrastriatal dopaminergic grafts in Parkinson's disease. Ann Neurol 1997;42:95-107.
    • (1997) Ann Neurol , vol.42 , pp. 95-107
    • Wenning, G.K.1    Odin, P.2    Morrish, P.3
  • 14
    • 0035826089 scopus 로고    scopus 로고
    • Transplantation of embryonic dopamine neurons for severe Parkinson's disease
    • Freed CR, Greene PE, Breeze RE, et al. Transplantation of embryonic dopamine neurons for severe Parkinson's disease. N Engl J Med 2001;344:710-719.
    • (2001) N Engl J Med , vol.344 , pp. 710-719
    • Freed, C.R.1    Greene, P.E.2    Breeze, R.E.3
  • 15
    • 0042837887 scopus 로고    scopus 로고
    • A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease
    • Olanow CW, Goetz CG, Kordower JH, et al. A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease. Ann Neurol 2003;54:403-414.
    • (2003) Ann Neurol , vol.54 , pp. 403-414
    • Olanow, C.W.1    Goetz, C.G.2    Kordower, J.H.3
  • 16
    • 67349088356 scopus 로고    scopus 로고
    • Clinical pattern and risk factors for dyskinesias following fetal nigral transplantation in Parkinson's disease: a double blind video-based analysis
    • Olanow CW, Gracies J-M, Goetz C, et al. Clinical pattern and risk factors for dyskinesias following fetal nigral transplantation in Parkinson's disease: a double blind video-based analysis. Mov Disord 2009;24:336-343.
    • (2009) Mov Disord , vol.24 , pp. 336-343
    • Olanow, C.W.1    Gracies, J.-M.2    Goetz, C.3
  • 17
    • 0036307190 scopus 로고    scopus 로고
    • Dyskinesias following neural transplantation in Parkinson's disease
    • Hagell P, Piccini P, Bjorklund A, et al. Dyskinesias following neural transplantation in Parkinson's disease. Nat Neurosci 2002;5:627-628.
    • (2002) Nat Neurosci , vol.5 , pp. 627-628
    • Hagell, P.1    Piccini, P.2    Bjorklund, A.3
  • 18
    • 10744219751 scopus 로고    scopus 로고
    • Transplantation in Parkinson's disease: PET changes correlate with the amount of grafted tissue
    • Cochen V, Ribeiro MJ, Nguyen JP, et al. Transplantation in Parkinson's disease: PET changes correlate with the amount of grafted tissue. Mov Disord 2003;18:928-932.
    • (2003) Mov Disord , vol.18 , pp. 928-932
    • Cochen, V.1    Ribeiro, M.J.2    Nguyen, J.P.3
  • 19
    • 0036120029 scopus 로고    scopus 로고
    • Simultaneous intrastriatal and intranigral fetal dopaminergic grafts in patients with Parkinson disease: a pilot study. report of three cases
    • Mendez I, Dagher A, Hong M, et al. Simultaneous intrastriatal and intranigral fetal dopaminergic grafts in patients with Parkinson disease: a pilot study. report of three cases. J Neurosurg 2002;96:589-596.
    • (2002) J Neurosurg , vol.96 , pp. 589-596
    • Mendez, I.1    Dagher, A.2    Hong, M.3
  • 20
    • 21944436225 scopus 로고    scopus 로고
    • Cell type analysis of functional fetal dopamine cell suspension transplants in the striatum and substantia nigra of patients with Parkinson's disease
    • Mendez I, Sanchez-Pernaute R, Cooper O, et al. Cell type analysis of functional fetal dopamine cell suspension transplants in the striatum and substantia nigra of patients with Parkinson's disease. Brain 2005;128(pt 7):1498-1510.
    • (2005) Brain , vol.128 , Issue.PART 7 , pp. 1498-1510
    • Mendez, I.1    Sanchez-Pernaute, R.2    Cooper, O.3
  • 21
    • 75149140104 scopus 로고    scopus 로고
    • Dopamine cell implantation in Parkinson's disease: long-term clinical and (18)F-FDOPA PET outcomes
    • Ma Y, Tang C, Chaly T, et al. Dopamine cell implantation in Parkinson's disease: long-term clinical and (18)F-FDOPA PET outcomes. J Nucl Med 2010;51:7-15.
    • (2010) J Nucl Med , vol.51 , pp. 7-15
    • Ma, Y.1    Tang, C.2    Chaly, T.3
  • 22
    • 43249114934 scopus 로고    scopus 로고
    • Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease
    • Kordower JH, Chu Y, Hauser RA, Freeman TB, Olanow CW. Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease. Nat Med 2008;14:504-506.
    • (2008) Nat Med , vol.14 , pp. 504-506
    • Kordower, J.H.1    Chu, Y.2    Hauser, R.A.3    Freeman, T.B.4    Olanow, C.W.5
  • 23
    • 61449216234 scopus 로고    scopus 로고
    • Transplanted dopaminergic neurons develop PD pathologic changes: a second case report
    • Kordower JH, Chu Y, Hauser RA, Olanow CW, Freeman TB. Transplanted dopaminergic neurons develop PD pathologic changes: a second case report. Mov Disord 2008;23:2303-2306.
    • (2008) Mov Disord , vol.23 , pp. 2303-2306
    • Kordower, J.H.1    Chu, Y.2    Hauser, R.A.3    Olanow, C.W.4    Freeman, T.B.5
  • 24
    • 0031922226 scopus 로고    scopus 로고
    • Fetal nigral grafts survive and mediate clinical benefit in a patient with Parkinson's disease
    • Kordower JH, Freeman TB, Chen EY, et al. Fetal nigral grafts survive and mediate clinical benefit in a patient with Parkinson's disease. Mov Disord 1998;13:383-393.
    • (1998) Mov Disord , vol.13 , pp. 383-393
    • Kordower, J.H.1    Freeman, T.B.2    Chen, E.Y.3
  • 25
    • 0028911848 scopus 로고
    • Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease
    • Kordower JH, Freeman TB, Snow BJ, et al. Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease. N Engl J Med 1995;332:1118-1124.
    • (1995) N Engl J Med , vol.332 , pp. 1118-1124
    • Kordower, J.H.1    Freeman, T.B.2    Snow, B.J.3
  • 26
    • 8944230650 scopus 로고    scopus 로고
    • Functional fetal nigral grafts in a patient with Parkinson's disease: chemoanatomic, ultrastructural, and metabolic studies
    • Kordower JH, Rosenstein JM, Collier TJ, et al. Functional fetal nigral grafts in a patient with Parkinson's disease: chemoanatomic, ultrastructural, and metabolic studies. J Comp Neurol 1996;370:203-230.
    • (1996) J Comp Neurol , vol.370 , pp. 203-230
    • Kordower, J.H.1    Rosenstein, J.M.2    Collier, T.J.3
  • 27
    • 43249110200 scopus 로고    scopus 로고
    • Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
    • Li JY, Englund E, Holton JL, et al. Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation. Nat Med 2008;14:501-503.
    • (2008) Nat Med , vol.14 , pp. 501-503
    • Li, J.Y.1    Englund, E.2    Holton, J.L.3
  • 28
    • 43249085326 scopus 로고    scopus 로고
    • Dopamine neurons implanted into people with Parkinson's disease survive without pathology for 14 years
    • Mendez I, Vinuela A, Astradsson A, et al. Dopamine neurons implanted into people with Parkinson's disease survive without pathology for 14 years. Nat Med 2008;14:507-509.
    • (2008) Nat Med , vol.14 , pp. 507-509
    • Mendez, I.1    Vinuela, A.2    Astradsson, A.3
  • 29
    • 77949820437 scopus 로고    scopus 로고
    • Characterization of Lewy body pathology in 12- and 16-year-old intrastriatal mesencephalic grafts surviving in a patient with Parkinson's disease
    • Li JY, Englund E, Widner H, et al. Characterization of Lewy body pathology in 12- and 16-year-old intrastriatal mesencephalic grafts surviving in a patient with Parkinson's disease. Mov Disord 2010;25:1091-1096.
    • (2010) Mov Disord , vol.25 , pp. 1091-1096
    • Li, J.Y.1    Englund, E.2    Widner, H.3
  • 30
    • 0033491121 scopus 로고    scopus 로고
    • Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient
    • Piccini P, Brooks DJ, Bjorklund A, et al. Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient. Nat Neurosci 1999;2:1137-1140.
    • (1999) Nat Neurosci , vol.2 , pp. 1137-1140
    • Piccini, P.1    Brooks, D.J.2    Bjorklund, A.3
  • 31
    • 84859496019 scopus 로고    scopus 로고
    • Serotonin neuron loss and nonmotor symptoms continue in Parkinson's patients treated with dopamine grafts [serial online]
    • Politis M, Wu K, Loane C, et al. Serotonin neuron loss and nonmotor symptoms continue in Parkinson's patients treated with dopamine grafts [serial online]. Sci Transl Med 2012;4:128ra141.
    • (2012) Sci Transl Med , vol.4
    • Politis, M.1    Wu, K.2    Loane, C.3
  • 32
    • 77955617871 scopus 로고    scopus 로고
    • Serotonergic neurons mediate dyskinesia side effects in Parkinson's patients with neural transplants [serial online]
    • Politis M, Wu K, Loane C, et al. Serotonergic neurons mediate dyskinesia side effects in Parkinson's patients with neural transplants [serial online]. Sci Transl Med 2010;2:38ra46.
    • (2010) Sci Transl Med , vol.2
    • Politis, M.1    Wu, K.2    Loane, C.3
  • 33
    • 0033767269 scopus 로고    scopus 로고
    • Delayed recovery of movement-related cortical function in Parkinson's disease after striatal dopaminergic grafts
    • Piccini P, Lindvall O, Bjorklund A, et al. Delayed recovery of movement-related cortical function in Parkinson's disease after striatal dopaminergic grafts. Ann Neurol 2000;48:689-695.
    • (2000) Ann Neurol , vol.48 , pp. 689-695
    • Piccini, P.1    Lindvall, O.2    Bjorklund, A.3
  • 34
    • 28544441892 scopus 로고    scopus 로고
    • Factors affecting the clinical outcome after neural transplantation in Parkinson's disease
    • Piccini P, Pavese N, Hagell P, et al. Factors affecting the clinical outcome after neural transplantation in Parkinson's disease. Brain 2005;128(pt 12):2977-2986.
    • (2005) Brain , vol.128 , Issue.PART 12 , pp. 2977-2986
    • Piccini, P.1    Pavese, N.2    Hagell, P.3
  • 35
    • 32544432029 scopus 로고    scopus 로고
    • Non-motor symptoms of Parkinson's disease: diagnosis and management
    • Chaudhuri KR, Healy DG, Schapira AH. Non-motor symptoms of Parkinson's disease: diagnosis and management. Lancet Neurol 2006;5:235-245.
    • (2006) Lancet Neurol , vol.5 , pp. 235-245
    • Chaudhuri, K.R.1    Healy, D.G.2    Schapira, A.H.3
  • 36
    • 69549126673 scopus 로고    scopus 로고
    • Serotonin and Parkinson's disease: on movement, mood, and madness
    • Fox SH, Chuang R, Brotchie JM. Serotonin and Parkinson's disease: on movement, mood, and madness. Mov Disord 2009;24:1255-1266.
    • (2009) Mov Disord , vol.24 , pp. 1255-1266
    • Fox, S.H.1    Chuang, R.2    Brotchie, J.M.3
  • 37
    • 78049460075 scopus 로고    scopus 로고
    • Fatigue in Parkinson's disease is linked to striatal and limbic serotonergic dysfunction
    • Pavese N, Metta V, Bose SK, Chaudhuri KR, Brooks DJ. Fatigue in Parkinson's disease is linked to striatal and limbic serotonergic dysfunction. Brain 2010;133:3434-3443.
    • (2010) Brain , vol.133 , pp. 3434-3443
    • Pavese, N.1    Metta, V.2    Bose, S.K.3    Chaudhuri, K.R.4    Brooks, D.J.5
  • 38
    • 33747200803 scopus 로고    scopus 로고
    • Deep brain stimulation of the internal segment of the globus pallidus in delayed runaway dyskinesia
    • Graff-Radford J, Foote KD, Rodriguez RL, et al. Deep brain stimulation of the internal segment of the globus pallidus in delayed runaway dyskinesia. Arch Neurol 2006;63:1181-1184.
    • (2006) Arch Neurol , vol.63 , pp. 1181-1184
    • Graff-Radford, J.1    Foote, K.D.2    Rodriguez, R.L.3
  • 39
    • 52649157756 scopus 로고    scopus 로고
    • Deep brain stimulation in Parkinson's disease following fetal nigral transplantation
    • Herzog J, Pogarell O, Pinsker MO, et al. Deep brain stimulation in Parkinson's disease following fetal nigral transplantation. Mov Disord 2008;23:1293-1296.
    • (2008) Mov Disord , vol.23 , pp. 1293-1296
    • Herzog, J.1    Pogarell, O.2    Pinsker, M.O.3
  • 40
    • 68549099660 scopus 로고    scopus 로고
    • Priming for L-DOPA-induced abnormal involuntary movements increases the severity of amphetamine-induced dyskinesia in grafted rats
    • Lane EL, Vercammen L, Cenci MA, Brundin P. Priming for L-DOPA-induced abnormal involuntary movements increases the severity of amphetamine-induced dyskinesia in grafted rats. Exp Neurol 2009;219:355-358.
    • (2009) Exp Neurol , vol.219 , pp. 355-358
    • Lane, E.L.1    Vercammen, L.2    Cenci, M.A.3    Brundin, P.4
  • 41
    • 33244459813 scopus 로고    scopus 로고
    • Graft placement and uneven pattern of reinnervation in the striatum is important for development of graft-induced dyskinesia
    • Carlsson T, Winkler C, Lundblad M, Cenci MA, Bjorklund A, Kirik D. Graft placement and uneven pattern of reinnervation in the striatum is important for development of graft-induced dyskinesia. Neurobiol Dis 2006;21:657-668.
    • (2006) Neurobiol Dis , vol.21 , pp. 657-668
    • Carlsson, T.1    Winkler, C.2    Lundblad, M.3    Cenci, M.A.4    Bjorklund, A.5    Kirik, D.6
  • 42
    • 29144490744 scopus 로고    scopus 로고
    • Focal not widespread grafts induce novel dyskinetic behavior in parkinsonian rats
    • Maries E, Kordower JH, Chu Y, et al. Focal not widespread grafts induce novel dyskinetic behavior in parkinsonian rats. Neurobiol Dis 2006;21:165-180.
    • (2006) Neurobiol Dis , vol.21 , pp. 165-180
    • Maries, E.1    Kordower, J.H.2    Chu, Y.3
  • 43
    • 80052971467 scopus 로고    scopus 로고
    • Graft-induced dyskinesias in Parkinson's disease: high striatal serotonin/dopamine transporter ratio
    • Politis M, Oertel WH, Wu K, et al. Graft-induced dyskinesias in Parkinson's disease: high striatal serotonin/dopamine transporter ratio. Mov Disord 2011;26:1997-2003.
    • (2011) Mov Disord , vol.26 , pp. 1997-2003
    • Politis, M.1    Oertel, W.H.2    Wu, K.3
  • 44
    • 60149088032 scopus 로고    scopus 로고
    • Impact of grafted serotonin and dopamine neurons on development of L-DOPA-induced dyskinesias in parkinsonian rats is determined by the extent of dopamine neuron degeneration
    • Carlsson T, Carta M, Munoz A, Mattsson B, Winkler C, Kirik D, Bjorklund A. Impact of grafted serotonin and dopamine neurons on development of L-DOPA-induced dyskinesias in parkinsonian rats is determined by the extent of dopamine neuron degeneration. Brain 2009;132(pt 2):319-335.
    • (2009) Brain , vol.132 , Issue.PART 2 , pp. 319-335
    • Carlsson, T.1    Carta, M.2    Munoz, A.3    Mattsson, B.4    Winkler, C.5    Kirik, D.6    Bjorklund, A.7
  • 45
    • 79551519276 scopus 로고    scopus 로고
    • α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells
    • Hansen C, Angot E, Bergstrom AL, et al. α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells. J Clin Invest 2011;121:715-725.
    • (2011) J Clin Invest , vol.121 , pp. 715-725
    • Hansen, C.1    Angot, E.2    Bergstrom, A.L.3
  • 46
    • 65349181409 scopus 로고    scopus 로고
    • Prospects of stem cell therapy for replacing dopamine neurons in Parkinson's disease
    • Lindvall O, Kokaia Z. Prospects of stem cell therapy for replacing dopamine neurons in Parkinson's disease. Trends in pharmacological sciences 2009;30:260-267.
    • (2009) Trends in pharmacological sciences , vol.30 , pp. 260-267
    • Lindvall, O.1    Kokaia, Z.2
  • 47
    • 84355166561 scopus 로고    scopus 로고
    • Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease
    • Kriks S, Shim JW, Piao J, et al. Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease. Nature 2011;480:547-551.
    • (2011) Nature , vol.480 , pp. 547-551
    • Kriks, S.1    Shim, J.W.2    Piao, J.3
  • 48
    • 77957670482 scopus 로고    scopus 로고
    • Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats
    • Hargus G, Cooper O, Deleidi M, et al. Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats. Proc Natl Acad Sci U S A 2010;107:15921-15926.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 15921-15926
    • Hargus, G.1    Cooper, O.2    Deleidi, M.3
  • 49
    • 80051674431 scopus 로고    scopus 로고
    • Direct generation of functional dopaminergic neurons from mouse and human fibroblasts
    • Caiazzo M, Dell'Anno MT, Dvoretskova E, et al. Direct generation of functional dopaminergic neurons from mouse and human fibroblasts. Nature 2011;476:224-227.
    • (2011) Nature , vol.476 , pp. 224-227
    • Caiazzo, M.1    Dell'Anno, M.T.2    Dvoretskova, E.3
  • 50
    • 79959951387 scopus 로고    scopus 로고
    • Direct conversion of human fibroblasts to dopaminergic neurons
    • Pfisterer U, Kirkeby A, Torper O, et al. Direct conversion of human fibroblasts to dopaminergic neurons. Proc Natl Acad Sci U S A 2011;108:10343-10348.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 10343-10348
    • Pfisterer, U.1    Kirkeby, A.2    Torper, O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.