메뉴 건너뛰기




Volumn 110, Issue 10, 2013, Pages 1751-1759

Disturbance in uniformly 13C-labelled DHA metabolism in elderly human subjects carrying the apoE Î4 allele

Author keywords

Oxidation; ApoE 4; DHA; Metabolism

Indexed keywords

ACETYLSALICYLIC ACID; ANTIHYPERTENSIVE AGENT; BISPHOSPHONIC ACID DERIVATIVE; CARBON 13; CARBON DIOXIDE; DOCOSAHEXAENOIC ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LEVOTHYROXINE; APOLIPOPROTEIN E4; CARBON; FAT INTAKE;

EID: 84887247737     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114513001268     Document Type: Article
Times cited : (78)

References (58)
  • 1
    • 33749154105 scopus 로고    scopus 로고
    • Effects of omega-3 fatty acids on serum markers of cardiovascular disease risk: A systematic review
    • DOI 10.1016/j.atherosclerosis.2006.02.012, PII S0021915006000694
    • Balk EM, Lichtenstein AH, Chung M, et al. (2006) Effects of omega-3 fatty acids on serum markers of cardiovascular disease risk: a systematic review. Atherosclerosis 189, 19-30. (Pubitemid 44468073)
    • (2006) Atherosclerosis , vol.189 , Issue.1 , pp. 19-30
    • Balk, E.M.1    Lichtenstein, A.H.2    Chung, M.3    Kupelnick, B.4    Chew, P.5    Lau, J.6
  • 2
    • 84861676215 scopus 로고    scopus 로고
    • Omega-3 fatty acids and HDL.How do they work in the prevention of cardiovascular disease
    • Burillo E, Martin-Fuentes P, Mateo-Gallego R, et al. (2012) Omega-3 fatty acids and HDL. How do they work in the prevention of cardiovascular disease? Curr Vasc Pharmacol 10, 432-441.
    • (2012) Curr Vasc Pharmacol , vol.10 , pp. 432-441
    • Burillo, E.1    Martin-Fuentes, P.2    Mateo-Gallego, R.3
  • 4
    • 68049087902 scopus 로고    scopus 로고
    • Fish, docosahexaenoic acid and Alzheimer's disease
    • Cunnane SC, Plourde M, Pifferi F, et al. (2009) Fish, docosahexaenoic acid and Alzheimer's disease. Prog Lipid Res 48, 239-256.
    • (2009) Prog. Lipid. Res. , vol.48 , pp. 239-256
    • Cunnane, S.C.1    Plourde, M.2    Pifferi, F.3
  • 5
    • 62549148261 scopus 로고    scopus 로고
    • Fish consumption, long-chain omega-3 fatty acids and risk of cognitive decline or Alzheimer disease: A complex association
    • Fotuhi M, Mohassel P & Yaffe K (2009) Fish consumption, long-chain omega-3 fatty acids and risk of cognitive decline or Alzheimer disease: a complex association. Nat Clin Pract Neurol 5, 140-152.
    • (2009) Nat. Clin. Pract. Neurol. , vol.5 , pp. 140-152
    • Fotuhi, M.1    Mohassel, P.2    Yaffe, K.3
  • 6
    • 34147107925 scopus 로고    scopus 로고
    • Plasma n-3 fatty acids and the risk of cognitive decline in older adults: The atherosclerosis risk in communities study
    • Beydoun MA, Kaufman JS, Satia JA, et al. (2007) Plasma n-3 fatty acids and the risk of cognitive decline in older adults: the Atherosclerosis Risk in Communities Study. Am J Clin Nutr 85, 1103-1111. (Pubitemid 46557928)
    • (2007) American Journal of Clinical Nutrition , vol.85 , Issue.4 , pp. 1103-1111
    • Beydoun, M.A.1    Kaufman, J.S.2    Satia, J.A.3    Rosamond, W.4    Folsom, A.R.5
  • 7
    • 0037395566 scopus 로고    scopus 로고
    • Cognitive decline and fatty acid composition of erythrocyte membranes-The EVA Study
    • Heude B, Ducimetiere P & Berr C (2003) Cognitive decline and fatty acid composition of erythrocyte membranes-The EVA Study. Am J Clin Nutr 77, 803-808.
    • (2003) Am. J. Clin. Nutr. , vol.77 , pp. 803-808
    • Heude, B.1    Ducimetiere, P.2    Berr, C.3
  • 8
    • 59449085082 scopus 로고    scopus 로고
    • Phospholipase A2 activation as a therapeutic approach for cognitive enhancement in early-stage Alzheimer disease
    • Schaeffer EL, Forlenza OV & Gattaz WF (2009) Phospholipase A2 activation as a therapeutic approach for cognitive enhancement in early-stage Alzheimer disease. Psychopharmacology (Berl) 202, 37-51.
    • (2009) Psychopharmacology (Berl) , vol.202 , pp. 37-51
    • Schaeffer, E.L.1    Forlenza, O.V.2    Gattaz, W.F.3
  • 9
    • 80053637923 scopus 로고    scopus 로고
    • V-3 Fatty acids and cognitive decline: Modulation by Apo-Eepsilon4 allele and depression
    • se13-2317.e22
    • Samieri C, Feart C, Proust-Lima C, et al. (2011) v-3 Fatty acids and cognitive decline: modulation by Apo-Eepsilon4 allele and depression. Neurobiol Aging 32, 2317.e13-2317.e22.
    • (2011) Neurobiol Aging , vol.32 , pp. 2317
    • Samieri, C.1    Feart, C.2    Proust-Lima, C.3
  • 13
    • 0344329878 scopus 로고    scopus 로고
    • Health benefits of docosahexaenoic acid (DHA)
    • DOI 10.1006/phrs.1999.0495
    • Horrocks LA & Yeo YK (1999) Health benefits of docosahexaenoic acid (DHA). Pharmacol Res 40, 211-225. (Pubitemid 29435720)
    • (1999) Pharmacological Research , vol.40 , Issue.3 , pp. 211-225
    • Horrocks, L.A.1    Yeo, Y.K.2
  • 15
    • 67949089699 scopus 로고    scopus 로고
    • Fish-oil supplementation induces antiinflammatory gene expression profiles in human blood mononuclear cells
    • Bouwens M, van de Rest O, Dellschaft N, et al. (2009) Fish-oil supplementation induces antiinflammatory gene expression profiles in human blood mononuclear cells. Am J Clin Nutr 90, 415-424.
    • (2009) Am. J. Clin. Nutr. , vol.90 , pp. 415-424
    • Bouwens, M.1    Van De Rest, O.2    Dellschaft, N.3
  • 16
    • 34447331361 scopus 로고    scopus 로고
    • Extremely limited synthesis of long chain polyunsaturates in adults: Implications for their dietary essentiality and use as supplements
    • Plourde M & Cunnane SC (2007) Extremely limited synthesis of long chain polyunsaturates in adults: implications for their dietary essentiality and use as supplements. Appl Physiol Nutr Metab 32, 619-634.
    • (2007) Appl. Physio. Nutr. Metab. , vol.32 , pp. 619-634
    • Plourde, M.1    Cunnane, S.C.2
  • 19
    • 73649133302 scopus 로고    scopus 로고
    • Plasma n-3 fatty acid response to an n-3 fatty acid supplement is modulated by apoE epsilon4 but not by the common PPAR-alpha L162 v polymorphism in men
    • Plourde M, Vohl MC, Vandal M, et al. (2009) Plasma n-3 fatty acid response to an n-3 fatty acid supplement is modulated by apoE epsilon4 but not by the common PPAR-alpha L162 V polymorphism in men. Br J Nutr 102, 1121-1124.
    • (2009) Br. J. Nutr. , vol.102 , pp. 1121-1124
    • Plourde, M.1    Vohl, M.C.2    Vandal, M.3
  • 21
    • 0030781741 scopus 로고    scopus 로고
    • Use of stable isotopes to study fatty acid and lipoprotein metabolism in man
    • Brenna JT (1997) Use of stable isotopes to study fatty acid and lipoprotein metabolism in man. Prostaglandins Leukot Essent Fatty Acids 57, 467-472. (Pubitemid 27504745)
    • (1997) Prostaglandins Leukotrienes and Essential Fatty Acids , vol.57 , Issue.4-5 , pp. 467-472
    • Brenna, J.T.1
  • 24
    • 79251576788 scopus 로고    scopus 로고
    • Plasma incorporation, apparent retroconversion and betaoxidation of 13C-docosahexaenoic acid in the elderly
    • Plourde M, Chouinard-Watkins R, Vandal M, et al. (2011) Plasma incorporation, apparent retroconversion and betaoxidation of 13C-docosahexaenoic acid in the elderly. Nutr Metab (Lond) 8, 5.
    • (2011) Nutr Metab (Lond) , Issue.8 , pp. 5
    • Plourde, M.1    Chouinard-Watkins, R.2    Vandal, M.3
  • 26
    • 65249181503 scopus 로고    scopus 로고
    • Metabolic response to a ketogenic breakfast in the healthy elderly
    • Freemantle E, Vandal M, Tremblay Mercier J, et al. (2009) Metabolic response to a ketogenic breakfast in the healthy elderly. J Nutr Health Aging 13, 293-298.
    • (2009) J. Nutr. Health Aging , vol.13 , pp. 293-298
    • Freemantle, E.1    Vandal, M.2    Tremblay Mercier, J.3
  • 28
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipides from animal tissues
    • Folch J, Lees M & Sloane Stanley GH (1957) A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 226, 497-509.
    • (1957) J. Biol. Chem. , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane Stanley, G.H.3
  • 29
    • 0027120290 scopus 로고
    • High sensitivity tracer detection using high-precision gas chromatography-combustion isotope ratio mass spectrometry and highly enriched [U-13C]-labeled precursors
    • Goodman KJ & Brenna JT (1992) High sensitivity tracer detection using high-precision gas chromatography-combustion isotope ratio mass spectrometry and highly enriched [U-13C]-labeled precursors. Anal Chem 64, 1088-1095.
    • (1992) Anal Chem , vol.64 , pp. 1088-1095
    • Goodman, K.J.1    Brenna, J.T.2
  • 30
    • 70349668471 scopus 로고    scopus 로고
    • Predicting energy expenditure in elders with the metabolic cost of activities
    • Choquette S, Chuin A, Lalancette DA, et al. (2009) Predicting energy expenditure in elders with the metabolic cost of activities. Med Sci Sports Exerc 41, 1915-1920.
    • (2009) Med Sci Sports Exerc , vol.41 , pp. 1915-1920
    • Choquette, S.1    Chuin, A.2    Lalancette, D.A.3
  • 31
    • 0024119002 scopus 로고
    • Genotyping and sequence analysis of apolipoprotein e isoforms
    • Emi M, Wu LL, Robertson MA, et al. (1988) Genotyping and sequence analysis of apolipoprotein E isoforms. Genomics 3, 373-379.
    • (1988) Genomics , vol.3 , pp. 373-379
    • Emi, M.1    Wu, L.L.2    Robertson, M.A.3
  • 32
    • 0025257612 scopus 로고
    • Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI
    • Hixson JE & Vernier DT (1990) Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. J Lipid Res 31, 545-548. (Pubitemid 20107994)
    • (1990) Journal of Lipid Research , vol.31 , Issue.3 , pp. 545-548
    • Hixson, J.E.1    Vernier, D.T.2
  • 33
    • 0003632935 scopus 로고
    • 7th ed. 507 Iowa State University, IA: Iowa State University Press
    • Cochran GWSWG (1980) Statistical Methods, 7th ed., pp. 507. Iowa State University, IA: Iowa State University Press.
    • (1980) Statistical Methods
    • Gwswg, C.1
  • 34
    • 12744254968 scopus 로고    scopus 로고
    • Population prevalence of APOE, APOC3 and PPAR-alpha mutations associated to hypertriglyceridemia in French Canadians
    • Garenc C, Aubert S, Laroche J, et al. (2004) Population prevalence of APOE, APOC3 and PPAR-alpha mutations associated to hypertriglyceridemia in French Canadians. J Hum Genet 49, 691-700.
    • (2004) J. Hum. Genet. , vol.49 , pp. 691-700
    • Garenc, C.1    Aubert, S.2    Laroche, J.3
  • 36
    • 0032044405 scopus 로고    scopus 로고
    • Statistical Analysis of Repeated Measures Data Using SAS Procedures
    • Littell RC, Henry PR & Ammerman CB (1998) Statistical analysis of repeated measures data using SAS procedures. J Anim Sci 76, 1216-1231. (Pubitemid 128437870)
    • (1998) Journal of Animal Science , vol.76 , Issue.4 , pp. 1216-1231
    • Littell, R.C.1    Henry, P.R.2    Ammerman, C.B.3
  • 37
    • 42249103252 scopus 로고    scopus 로고
    • Fatty acids, lipid metabolism and Alzheimer pathology
    • Hooijmans CR & Kiliaan AJ (2008) Fatty acids, lipid metabolism and Alzheimer pathology. Eur J Pharmacol 585, 176-196.
    • (2008) Eur. J. Pharmacol. , vol.585 , pp. 176-196
    • Hooijmans, C.R.1    Kiliaan, A.J.2
  • 38
    • 0032895028 scopus 로고    scopus 로고
    • Remnant lipoprotein metabolism: Key pathways involving cell-surface heparan sulfate proteoglycans and apolipoprotein E
    • Mahley RW & Ji ZS (1999) Remnant lipoprotein metabolism: key pathways involving cell-surface heparan sulfate proteoglycans and apolipoprotein E. J Lipid Res 40, 1-16. (Pubitemid 29022581)
    • (1999) Journal of Lipid Research , vol.40 , Issue.1 , pp. 1-16
    • Mahley, R.W.1    Ji, Z.-S.2
  • 39
    • 58149389414 scopus 로고    scopus 로고
    • Apolipoprotein gene polymorphisms and plasma levels in healthy Tunisians and patients with coronary artery disease
    • Bahri R, Esteban E, Moral P, et al. (2008) Apolipoprotein gene polymorphisms and plasma levels in healthy Tunisians and patients with coronary artery disease. Lipids Health Dis 7, 46.
    • (2008) Lipids Health Dis. , vol.7 , pp. 46
    • Bahri, R.1    Esteban, E.2    Moral, P.3
  • 41
    • 77957710737 scopus 로고    scopus 로고
    • Interactions between age and apoE genotype on fasting and postprandial triglycerides levels
    • Carvalho-Wells AL, Jackson KG, Gill R, et al. (2010) Interactions between age and apoE genotype on fasting and postprandial triglycerides levels. Atherosclerosis 212, 481-487.
    • (2010) Atherosclerosis , vol.212 , pp. 481-487
    • Carvalho-Wells, A.L.1    Jackson, K.G.2    Gill, R.3
  • 42
    • 0035864691 scopus 로고    scopus 로고
    • Effect of apolipoprotein E3/4 phenotype on postprandial triglycerides and retinyl palmitate metabolism in plasma from hyperlipidemic subjects in Japan
    • DOI 10.1016/S0021-9150(00)00464-0, PII S0021915000004640
    • Kobayashi J, Saito Y, Taira K, et al. (2001) Effect of apolipoprotein E3/4 phenotype on postprandial triglycerides and retinyl palmitate metabolism in plasma from hyperlipidemic subjects in Japan. Atherosclerosis 154, 539-546. (Pubitemid 32232150)
    • (2001) Atherosclerosis , vol.154 , Issue.3 , pp. 539-546
    • Kobayashi, J.1    Saito, Y.2    Taira, K.3    Hikita, M.4    Takahashi, K.5    Bujo, H.6    Morisaki, N.7    Saito, Y.8
  • 43
    • 0036737723 scopus 로고    scopus 로고
    • The effect of age, body mass index, and fasting triglyceride level on postprandial lipemia is dependent on apolipoprotein e polymorphism in subjects with non-insulin-dependent diabetes mellitus
    • Reznik Y, Morello R, Pousse P, et al. (2002) The effect of age, body mass index, and fasting triglyceride level on postprandial lipemia is dependent on apolipoprotein E polymorphism in subjects with non-insulin-dependent diabetes mellitus. Metabolism 51, 1088-1092.
    • (2002) Metabolism , vol.51 , pp. 1088-1092
    • Reznik, Y.1    Morello, R.2    Pousse, P.3
  • 44
    • 0034913794 scopus 로고    scopus 로고
    • The role of docosahexaenoic acid containing phospholipids in modulating G protein-coupled signaling pathways: Visual transduction
    • DOI 10.1385/JMN:16:2-3:237
    • Litman BJ, Niu SL, Polozova A, et al. (2001) The role of docosahexaenoic acid containing phospholipids in modulating G protein-coupled signaling pathways: visual transduction. J Mol Neurosci 16, 237-242, discussion 79-84. (Pubitemid 32664785)
    • (2001) Journal of Molecular Neuroscience , vol.16 , Issue.2-3 , pp. 237-242
    • Litman, B.J.1    Niu, S.-L.2    Polozova, A.3    Mitchell, D.C.4
  • 45
    • 0034675852 scopus 로고    scopus 로고
    • Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing
    • Serhan CN, Clish CB, Brannon J, et al. (2000) Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing. J Exp Med 192, 1197-1204.
    • (2000) J. Exp. Med. , vol.192 , pp. 1197-1204
    • Serhan, C.N.1    Clish, C.B.2    Brannon, J.3
  • 46
    • 0033553213 scopus 로고    scopus 로고
    • Delta3 5,7,Delta2 4, 6-trienoyl-CoA isomerase, a novel enzyme that functions in the beta-oxidation of polyunsaturated fatty acids with conjugated double bonds
    • Liang X, Zhu D & Schulz H (1999) Delta3,5,7,Delta2,4, 6-trienoyl-CoA isomerase, a novel enzyme that functions in the beta-oxidation of polyunsaturated fatty acids with conjugated double bonds. J Biol Chem 274, 13830-13835.
    • (1999) J. Biol. Chem. , vol.274 , pp. 13830-13835
    • Liang, X.1    Zhu, D.2    Schulz, H.3
  • 47
    • 84859397583 scopus 로고    scopus 로고
    • Potential roles of peroxisomes in Alzheimer's disease and in dementia of the Alzheimer's type
    • Lizard G, Rouaud O, Demarquoy J, et al. (2012) Potential roles of peroxisomes in Alzheimer's disease and in dementia of the Alzheimer's type. J Alzheimers Dis 29, 241-254.
    • (2012) J. Alzheimers. Dis. , vol.29 , pp. 241-254
    • Lizard, G.1    Rouaud, O.2    Demarquoy, J.3
  • 48
    • 33746754085 scopus 로고    scopus 로고
    • Polyunsaturated fatty acid concentrations in young men and women consuming their habitual diets
    • DOI 10.1079/BJN20061801
    • Bakewell L, Burdge GC & Calder PC (2006) Polyunsaturated fatty acid concentrations in young men and women consuming their habitual diets. Br J Nutr 96, 93-99. (Pubitemid 44160901)
    • (2006) British Journal of Nutrition , vol.96 , Issue.1 , pp. 93-99
    • Bakewell, L.1    Burdge, G.C.2    Calder, P.C.3
  • 49
    • 3042680440 scopus 로고    scopus 로고
    • α-Linolenic acid metabolism in men and women: Nutritional and biological implications
    • DOI 10.1097/00075197-200403000-00006
    • Burdge G (2004) Alpha-linolenic acid metabolism in men and women: nutritional and biological implications. Curr Opin Clin Nutr Metab Care 7, 137-144. (Pubitemid 40340675)
    • (2004) Current Opinion in Clinical Nutrition and Metabolic Care , vol.7 , Issue.2 , pp. 137-144
    • Burdge, G.1
  • 50
    • 82355190915 scopus 로고    scopus 로고
    • Sex-specific differences in essential fatty acid metabolism
    • Decsi T & Kennedy K (2011) Sex-specific differences in essential fatty acid metabolism. Am J Clin Nutr 94, Suppl. 6, 1914S-1919S.
    • (2011) Am. J. Clin. Nutr. , vol.94 , Issue.SUPPL. 6
    • Decsi, T.1    Kennedy, K.2
  • 51
    • 27244445146 scopus 로고    scopus 로고
    • Conversion of α-linolenic acid to longer-chain polyunsaturated fatty acids in human adults
    • DOI 10.1051/rnd:2005047
    • Burdge GC & Calder PC (2005) Conversion of alphalinolenic acid to longer-chain polyunsaturated fatty acids in human adults. Reprod Nutr Dev 45, 581-597. (Pubitemid 41511883)
    • (2005) Reproduction Nutrition Development , vol.45 , Issue.5 , pp. 581-597
    • Burdge, G.C.1    Calder, P.C.2
  • 52
    • 0142196218 scopus 로고    scopus 로고
    • Conversion of α-linolenic acid to palmitic, palmitoleic, stearic and oleic acids in men and women
    • DOI 10.1016/S0952-3278(03)00111-X
    • Burdge GC & Wootton SA (2003) Conversion of alphalinolenic acid to palmitic, palmitoleic, stearic and oleic acids in men and women. Prostaglandins Leukot Essent Fatty Acids 69, 283-290. (Pubitemid 37463810)
    • (2003) Prostaglandins Leukotrienes and Essential Fatty Acids , vol.69 , Issue.4 , pp. 283-290
    • Burdge, G.C.1    Wootton, S.A.2
  • 53
    • 0036774671 scopus 로고    scopus 로고
    • Conversion of α-linolenic acid to eicosapentaenoic, docosapentaenoic and docosahexaenoic acids in young women
    • Burdge GC & Wootton SA (2002) Conversion of alphalinolenic acid to eicosapentaenoic, docosapentaenoic and docosahexaenoic acids in young women. Br J Nutr 88, 411-420. (Pubitemid 35251957)
    • (2002) British Journal of Nutrition , vol.88 , Issue.4 , pp. 411-420
    • Burdge, G.C.1    Wootton, S.A.2
  • 54
    • 0036774711 scopus 로고    scopus 로고
    • Eicosapentaenoic and docosapentaenoic acids are the principal products of α-linolenic acid metabolism in young men
    • Burdge GC, Jones AE & Wootton SA (2002) Eicosapentaenoic and docosapentaenoic acids are the principal products of alpha-linolenic acid metabolism in young men. Br J Nutr 88, 355-363. (Pubitemid 35251952)
    • (2002) British Journal of Nutrition , vol.88 , Issue.4 , pp. 355-363
    • Burdge, G.C.1    Jones, A.E.2    Wootton, S.A.3
  • 58
    • 67349280899 scopus 로고    scopus 로고
    • Serum cholesterol, apolipoprotein e genotype and depressive symptoms in elderly European men: The FINE study
    • Giltay EJ, van Reedt Dortland AK, Nissinen A, et al. (2009) Serum cholesterol, apolipoprotein E genotype and depressive symptoms in elderly European men: the FINE study. J Affect Disord 115, 471-477.
    • (2009) J. Affect. Disord. , vol.115 , pp. 471-477
    • Giltay, E.J.1    Van Reedt Dortland, A.K.2    Nissinen, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.