Interactions between age and apoE genotype on fasting and postprandial triglycerides levels

Atherosclerosis

Volumn 212, Issue 2, 2010, Pages 481-487

  Carvalho Wells, Andrew L ^a   Jackson, Kim G ^a   Gill, Rosalynn ^b   Olano Martin, Estibaliz ^a   Lovegrove, Julie A ^a   Williams, Christine M ^a   Minihane, Anne M ^a  

^a UNIVERSITY OF READING   (United Kingdom)

^b Ipsogen Inc   (United States)

Author keywords

Apolipoprotein E genotype; Blood lipids; Cholesterol; Postprandial lipaemia; Triglycerides

Indexed keywords

APOLIPOPROTEIN E; DNA; GLUCOSE; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADULT; AGE; ARTICLE; BLOOD SAMPLING; BODY MASS; CHOLESTEROL BLOOD LEVEL; CLINICAL ASSESSMENT; DIET RESTRICTION; DNA EXTRACTION; FEMALE; GENE FREQUENCY; GENOTYPE; HUMAN; HYPERLIPIDEMIA; MALE; MEAL; NORMAL HUMAN; POSTPRANDIAL STATE; PRIORITY JOURNAL; TRIACYLGLYCEROL BLOOD LEVEL;

ADULT; AGE FACTORS; AGED; ALLELES; APOLIPOPROTEINS E; BODY MASS INDEX; CHOLESTEROL; CORONARY DISEASE; FEMALE; GENOTYPE; HETEROZYGOTE; HUMANS; MALE; MIDDLE AGED; MUTATION; POSTPRANDIAL PERIOD; RISK; TRIGLYCERIDES;

EID: 77957710737     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2010.06.036     Document Type: Article

References (43)

1. Bouchier I.A.D., Bronte-Stewart B. Alimentary lipemia and ischaemic heart disease. Lancet 1961, 277:363-366.
2. Groot P.H.E., Vanstiphout W., Krauss X.H., et al. Postprandial lipoprotein metabolism in normolipidemic men with and without coronary artery disease. Arterioscler Thromb 1991, 11:653-662.
3. Patsch J.R., Miesenbock G., Hopferwieser T., et al. Relation of triglyceride metabolism and coronary artery disease-studies in the postprandial state. Arterioscler Thromb 1992, 12:1336-1345.
4. Nordestgaard B.G., Benn M., Schnohr P., Tybjaerg-Hansen A. Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women. JAMA 2007, 298:299-308.
5. Bansal S., Buring J.E., Rifai N., Mora S., Sacks F.M., Ridker P.M. Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women. JAMA 2007, 298:309-316.
6. Cullen P. Evidence that triglycerides are an independent coronary heart disease risk factor. Am J Cardiol 2000, 86:943-949.
7. Austin M.A. Triacylglycerol and coronary heart disease. Proc Nutr Soc 1997, 56:667-670.
8. Roche H.M., Gibney M.J. Effect of long-chain n-3 polyunsaturated fatty acids on fasting and postprandial triacylglycerol metabolism1. Am J Clin Nutr 2000, 71:232-237.
9. Lopez-Miranda J., Williams C., Lairon D. Dietary, physiological, genetic and pathological influences on postprandial lipid metabolism. Br J Nutr 2007, 98:458-473.
10. Perez-Martinez P., Lopez-Miranda J., Perez-Jimenez F., Ordovas J.M. Influence of genetic factors in the modulation of postprandial lipemia. Atheroscler Suppl 2008, 9:49-55.
11. Mahley R.W. Apolipoprotein E-cholesterol transport protein with expanding role in cell biology. Science 1988, 240:622-630.
12. Weisgraber K.H. Apolipoprotein E: structure-function relationships. Advances in protein chemistry, vol. 45 1994, Academic Press Inc., San Diego, p. 249-302.
13. Tetali S.D., Budamagunta M.S., Voss J.C., Rutledge J.C. C-terminal interactions of apolipoprotein E4 respond to the postprandial state. J Lipid Res 2006, 47:1358-1365.
14. Miettinen T.A., Gylling H., Vanhanen H., Ollus A. Cholesterol absorption, elimination, and synthesis related to LDL kinetics during varying fat intake in men with different apoprotein E phenotypes. Arterioscler Thromb 1992, 12:1044-1052.
15. Minihane A.M., Jofre-Monseny L., Olano-Martin E., Rimbach G. ApoE genotype, cardiovascular risk and responsiveness to dietary fat manipulation. Proc Nutr Soc 2007, 66:183-197.
16. Huang Y.D., Ji Z.S., Brecht W.J., Rall S.C., Taylor J.M., Mahley R.W. Overexpression of apolipoprotein E3 in transgenic rabbits causes combined hyperlipidemia by stimulating hepatic VLDL production and impairing VLDL lipolysis. Arterioscler Thromb Vasc Biol 1999, 19:2952-2959.
17. Boerwinkle E., Brown S., Sharrett A.R., Heiss G., Patsch W. Apolipoprotein E polymorphism influences postprandial retinyl palmitate but not triglyceride concentrations. Am J Hum Genet 1994, 54:341-360.
18. Weintraub M.S., Eisenberg S., Breslow J.L. Dietary fat clearance in normal subjects is regulated by genetic variation in apolipoprotein E. J Clinical Invest 1987, 80:1571-1577.
19. Rimbach G., Minihane A.M. Nutrigenetics and personalised nutrition: how far have we progressed and are we likely to get there?. Proc Nutr Soc 2009, 68:162-172.
20. Olano-Martin E., Abraham E.C., Gill-Garrison R., et al. Influence of apoA-V gene variants on postprandial triglyceride metabolism: impact of gender. J Lipid Res 2008, 49:945-953.
21. 2+ high density lipoprotein cholesterol precipitation method for use with previously frozen plasma. Clin Chem 1994, 40:233-239.
22. Griffin B.A., Caslake M.J., Yip B., Tait G.W., Packard C.J., Shepherd J. Rapid isolation of low-density lipoprotein (LDL) subfractions from plasma by density gradient ultracentrifugation. Atherosclerosis 1990, 83:59-67.
23. Friedewald W.T., Levy R.J., Fredrickson D.S. Estimation of concentration of low density lipoprotein cholesterol in plasma, without use of preparative ultracentrifuge. Clinical Chem 1972, 18:499-502.
24. Frayn K.N. Metabolic regulation: a human perspective 2003, Portland Press, Oxford. 2nd ed.
25. Frayn K.N., Summers L.K.M., Fielding B.A. Regulation of the plasma non-esterified fatty acid concentration in the postprandial state. Proc Nutr Soc 1997, 56:713-721.
26. Bennet A.M., Di Angelantonio E., Ye Z., et al. Association of apolipoprotein E genotypes with lipid levels and coronary risk. JAMA 2007, 298:1300-1311.
27. Caslake M.J., Miles E.A., Kofler B.M., et al. Effect of sex and genotype on cardiovascular biomarker response to fish oils: the FINGEN Study. Am J Clin Nutr 2008, 88:618-629.
28. Skoglund-Andersson C., Ehrenborg E., Fisher R.M., Olivercrona G., Hamsten A., Karpe F. Influence of common variants in the CETP, LPL, HL and APO E genes on LDL heterogeneity in healthy, middle-aged men. Atherosclerosis 2003, 167:311-317.
29. Lipoprotein atherogenicity: an overview of current mechanisms. Meeting of the Nutrition-Society 1999, B.A. Griffin (Ed.).
30. Mahley R.W., Huang Y.D., Rall S.C. Pathogenesis of type III hyperlipoproteinemia (dysbetalipoproteinemia): questions, quandaries, and paradoxes. J Lipid Res 1999, 40:1933-1949.
31. Minihane A.M., Khan S., Leigh-Firbank E.C., et al. ApoE polymorphism and fish oil supplementation in subjects with an antherogenic lipoprotein phenotype. Arterioscler Thromb Vasc Biol 2000, 20:1990-1997.
32. Dart A., Sherrard B., Simpson H. Influence of apo E phenotype on postprandial triglyceride and glucose responses in subjects with and without coronary heart disease. Atherosclerosis 1997, 130:161-170.
33. Dart A.M., Cooper B. Independent effects of Apo E phenotype and plasma triglyceride on lipoprotein particle sizes in the fasting and postprandial states. Arterioscler Thromb Vasc Biol 1999, 19:2465-2473.
34. Kobayashi J., Saito Y., Taira K., et al. Effect of apolipoprotein E3/4 phenotype on postprandial triglycerides and retinyl palmitate metabolism in plasma from hyperlipidemic subjects in Japan. Atherosclerosis 2001, 154:539-546.
35. Dallongeville J., Tiret L., Visvikis S., et al. Effect of apo E phenotype on plasma postprandial triglyceride levels in young male adults with and without a familial history of myocardial infarction: the EARS II study. Atherosclerosis 1999, 145:381-388.
36. Huang Y., Liu X.Q., Rall S.C., et al. Overexpression and accumulation of apolipoprotein E as a cause of hypertriglyceridemia. J Biol Chem 1998, 273:26388-26393.
37. Rensen P.C.N., van Berkel T.J.C. Apolipoprotein E effectively inhibits lipoprotein lipase-mediated lipolysis of chylomicron-like triglyceride-rich lipid emulsions in vitro and in vivo. J Biol Chem 1996, 271:14791-14799.
38. Gregg R.E., Zech L.A., Schaefer E.J., Stark D., Wilson D., Brewer H.B. Abnormal in vivo metabolism of apolipoprotein E4 in humans. J Clin Invest 1986, 78:815-821.
39. Heeren J., Beisiegel U., Grewal T. Apolipoprotein E recycling implications for dyslipidemia and atherosclerosis. Arterioscler Thromb Vasc Biol 2006, 26:442-448.
40. Heeren J., Grewal T., Laatsch A., et al. Impaired recycling of apolipoprotein E4 is associated with intracellular cholesterol accumulation. J Biol Chem 2004, 279:55483-55492.
41. Fazio S., Major A.S., Swift L.L., et al. Increased atherosclerosis in LDL receptor-null mice lacking ACAT1 in macrophages. J Clin Invest 2001, 107:163-171.
42. Reznik Y., Morello R., Pousse P., Mahoudeau J., Fradin S. The effect of age, body mass index, and fasting triglyceride level on postprandial lipemia is dependent on apolipoprotein E polymorphism in subjects with non-insulin-dependent diabetes mellitus. Metabolism 2002, 51:1088-1092.
43. Stiefel P., Montilla C., Muniz-Grijalvo O., et al. Apolipoprotein E gene polymorphism is related to metabolic abnormalities, but does not influence erythrocyte membrane lipid composition or sodium-lithium countertransport activity in essential hypertension. Metabolism 2001, 50:157-160.