메뉴 건너뛰기




Volumn 172, Issue 3, 2013, Pages 832-840

Tumor growth inhibition through targeting liposomally bound curcumin to tumor vasculature

Author keywords

Curcumin formulations; Liposomal drug delivery; RGDK lipopeptides; Tumor growth inhibition; Tumor vasculature targeting

Indexed keywords

ANTI-TUMOR EFFICACY; CURCUMIN; DRUG DELIVERY SYSTEM; IMMUNOHISTOCHEMICAL STAINING; LIPOSOMAL FORMULATION; RGDK-LIPOPEPTIDES; TUMOR GROWTH; TUMOR VASCULATURE TARGETING;

EID: 84887199587     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.08.302     Document Type: Article
Times cited : (39)

References (49)
  • 1
    • 84875388603 scopus 로고    scopus 로고
    • The clinical applications of curcumin: Current state and the future
    • X. Fan, C. Zhang, D.B. Liu, J. Yan, and H.P. Liang The clinical applications of curcumin: current state and the future Curr. Pharm. Des. 19 2013 2011 2031
    • (2013) Curr. Pharm. Des. , vol.19 , pp. 2011-2031
    • Fan, X.1    Zhang, C.2    Liu, D.B.3    Yan, J.4    Liang, H.P.5
  • 2
    • 84875399748 scopus 로고    scopus 로고
    • A review of therapeutic effects of curcumin
    • A. Noorafshan, and S. Ashkani-Esfahani A review of therapeutic effects of curcumin Curr. Pharm. Des. 19 2013 2032 2046
    • (2013) Curr. Pharm. Des. , vol.19 , pp. 2032-2046
    • Noorafshan, A.1    Ashkani-Esfahani, S.2
  • 3
    • 23044479821 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane) inhibits constitutive NF-κB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma
    • DOI 10.1016/j.bcp.2005.04.043, PII S0006295205002418
    • S. Shishodia, H.M. Amin, R. Lai, and B.B. Aggarwal Curcumin (diferuloylmethane) inhibits constitutive NF-κB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma Biochem. Pharmacol. 70 2005 700 713 (Pubitemid 41058705)
    • (2005) Biochemical Pharmacology , vol.70 , Issue.5 , pp. 700-713
    • Shishodia, S.1    Amin, H.M.2    Lai, R.3    Aggarwal, B.B.4
  • 4
    • 0037069939 scopus 로고    scopus 로고
    • Curcumin-induced suppression of cell proliferation correlates with down-regulation of cyclin D1 expression and CDK4-mediated retinoblastoma protein phosphorylation
    • DOI 10.1038/sj.onc.1206048
    • A. Mukhopadhyay Curcumin-induced suppression of cell proliferation correlates with down-regulation of cyclin D1 expression and CDK4-mediated retinoblastoma protein phosphorylation Oncogene 21 2002 8852 8861 (Pubitemid 36132405)
    • (2002) Oncogene , vol.21 , Issue.57 , pp. 8852-8861
    • Mukhopadhyay, A.1    Banerjee, S.2    Stafford, L.J.3    Xia, C.4    Liu, M.5    Aggarwal, B.B.6
  • 5
    • 64249171413 scopus 로고    scopus 로고
    • Molecular mechanism of curcumin induced cytotoxicity in human cervical carcinoma cells
    • M. Singh, and N. Singh Molecular mechanism of curcumin induced cytotoxicity in human cervical carcinoma cells Mol. Cell. Biochem. 325 2009 107 119
    • (2009) Mol. Cell. Biochem. , vol.325 , pp. 107-119
    • Singh, M.1    Singh, N.2
  • 6
    • 30044446136 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IκBα kinase and Akt activation
    • DOI 10.1124/mol.105.017400
    • S. Aggarwal, H. Ichikawa, Y. Takada, S.K. Sandur, S. Shishodia, and B.B. Aggarwal Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IκBα kinase and Akt activation Mol. Pharmacol. 69 2006 195 206 (Pubitemid 43048906)
    • (2006) Molecular Pharmacology , vol.69 , Issue.1 , pp. 195-206
    • Aggarwal, S.1    Ichikawa, H.2    Takada, Y.3    Sandur, S.K.4    Shishodia, S.5    Aggarwal, B.B.6
  • 7
    • 79951601296 scopus 로고    scopus 로고
    • Upregulation of p53 expression in patients with colorectal cancer by administration of curcumin
    • Z.Y. He, C.B. Shi, H. Wen, F.L. Li, B.L. Wang, and J. Wang Upregulation of p53 expression in patients with colorectal cancer by administration of curcumin Cancer Invest. 29 2011 208 213
    • (2011) Cancer Invest. , vol.29 , pp. 208-213
    • He, Z.Y.1    Shi, C.B.2    Wen, H.3    Li, F.L.4    Wang, B.L.5    Wang, J.6
  • 8
    • 80053194778 scopus 로고    scopus 로고
    • Curcumin-induced mitotic spindle defect and cell cycle arrest in human bladder cancer cells occurs partly through inhibition of aurora A
    • H.S. Liu, C.S. Ke, H.C. Cheng, C.Y. Huang, and C.L. Su Curcumin-induced mitotic spindle defect and cell cycle arrest in human bladder cancer cells occurs partly through inhibition of aurora A Mol. Pharmacol. 80 2011 638 646
    • (2011) Mol. Pharmacol. , vol.80 , pp. 638-646
    • Liu, H.S.1    Ke, C.S.2    Cheng, H.C.3    Huang, C.Y.4    Su, C.L.5
  • 9
    • 78651272490 scopus 로고    scopus 로고
    • Curcumin counteracts the proliferative effect of estradiol and induces apoptosis in cervical cancer cells
    • M. Singh, and N. Singh Curcumin counteracts the proliferative effect of estradiol and induces apoptosis in cervical cancer cells Mol. Cell. Biochem. 347 2011 1 11
    • (2011) Mol. Cell. Biochem. , vol.347 , pp. 1-11
    • Singh, M.1    Singh, N.2
  • 10
    • 77955077389 scopus 로고    scopus 로고
    • Curcumin induces apoptosis in human non-small cell lung cancer NCI-H460 cells through ER stress and caspase cascade- and mitochondria-dependent pathways
    • S.H. Wu Curcumin induces apoptosis in human non-small cell lung cancer NCI-H460 cells through ER stress and caspase cascade- and mitochondria-dependent pathways Anticancer. Res. 30 2010 2125 2133
    • (2010) Anticancer. Res. , vol.30 , pp. 2125-2133
    • Wu, S.H.1
  • 11
    • 77955485060 scopus 로고    scopus 로고
    • Systemic administration of polymeric nanoparticle-encapsulated curcumin (NanoCurc) blocks tumor growth and metastases in preclinical models of pancreatic cancer
    • S. Bisht Systemic administration of polymeric nanoparticle-encapsulated curcumin (NanoCurc) blocks tumor growth and metastases in preclinical models of pancreatic cancer Mol. Cancer Ther. 9 2010 2255 2264
    • (2010) Mol. Cancer Ther. , vol.9 , pp. 2255-2264
    • Bisht, S.1
  • 12
    • 79955804832 scopus 로고    scopus 로고
    • Phase IIa clinical trial of curcumin for the prevention of colorectal neoplasia
    • R.E. Carroll Phase IIa clinical trial of curcumin for the prevention of colorectal neoplasia Cancer Prev. Res. (Phila.) 4 2011 354 364
    • (2011) Cancer Prev. Res. (Phila.) , vol.4 , pp. 354-364
    • Carroll, R.E.1
  • 14
    • 67349087690 scopus 로고    scopus 로고
    • Liver metastases after colonic carcinoma-palliative chemotherapy plus curcumin
    • C. Braumann, N. Guenther, L.M. Loeffler, and W. Dubiel Liver metastases after colonic carcinoma-palliative chemotherapy plus curcumin Int. J. Colorectal Dis. 24 2009 859 860
    • (2009) Int. J. Colorectal Dis. , vol.24 , pp. 859-860
    • Braumann, C.1    Guenther, N.2    Loeffler, L.M.3    Dubiel, W.4
  • 15
    • 48949086300 scopus 로고    scopus 로고
    • Phase II study of curcumin and gemcitabine in patients with advanced pancreatic cancer
    • R. Epelbaum, B. Vizel, and G. Bar-Sela Phase II study of curcumin and gemcitabine in patients with advanced pancreatic cancer J. Clin. Oncol. 26 2008 15619
    • (2008) J. Clin. Oncol. , vol.26 , pp. 15619
    • Epelbaum, R.1    Vizel, B.2    Bar-Sela, G.3
  • 16
    • 79959612772 scopus 로고    scopus 로고
    • A phase I/II study of gemcitabine-based chemotherapy plus curcumin for patients with gemcitabine-resistant pancreatic cancer
    • M. Kanai A phase I/II study of gemcitabine-based chemotherapy plus curcumin for patients with gemcitabine-resistant pancreatic cancer Cancer Chemother. Pharmacol. 68 2011 157 164
    • (2011) Cancer Chemother. Pharmacol. , vol.68 , pp. 157-164
    • Kanai, M.1
  • 17
    • 51649118928 scopus 로고    scopus 로고
    • Phase II trial of curcumin in patients with advanced pancreatic cancer
    • N. Dhillon Phase II trial of curcumin in patients with advanced pancreatic cancer Clin. Cancer Res. 14 2008 4491 4499
    • (2008) Clin. Cancer Res. , vol.14 , pp. 4491-4499
    • Dhillon, N.1
  • 18
    • 77954160638 scopus 로고    scopus 로고
    • Phase i dose escalation trial of docetaxel plus curcumin in patients with advanced and metastatic breast cancer
    • M. Bayet-Robert Phase I dose escalation trial of docetaxel plus curcumin in patients with advanced and metastatic breast cancer Cancer Biol. Ther. 9 2010 8 14
    • (2010) Cancer Biol. Ther. , vol.9 , pp. 8-14
    • Bayet-Robert, M.1
  • 21
    • 84875397668 scopus 로고    scopus 로고
    • Perspectives on new synthetic curcumin analogs and their potential anticancer properties
    • A. Vyas, P. Dandawate, S. Padhye, A. Ahmad, and F. Sarkar Perspectives on new synthetic curcumin analogs and their potential anticancer properties Curr. Pharm. Des. 19 2013 2047 2069
    • (2013) Curr. Pharm. Des. , vol.19 , pp. 2047-2069
    • Vyas, A.1    Dandawate, P.2    Padhye, S.3    Ahmad, A.4    Sarkar, F.5
  • 22
    • 24644508916 scopus 로고    scopus 로고
    • Liposome-encapsulated curcumin in vitro and in vivo effects on proliferation, apoptosis, signaling, and angiogenesis
    • L. Lan, B.S. Fadi, and K. Razelle Liposome-encapsulated curcumin in vitro and in vivo effects on proliferation, apoptosis, signaling, and angiogenesis Cancer 104 2005 1322 1331
    • (2005) Cancer , vol.104 , pp. 1322-1331
    • Lan, L.1    Fadi, B.S.2    Razelle, K.3
  • 23
    • 84870381912 scopus 로고    scopus 로고
    • A systemic administration of liposomal curcumin inhibits radiation pneumonitis and sensitizes lung carcinoma to radiation
    • H.S. Shi A systemic administration of liposomal curcumin inhibits radiation pneumonitis and sensitizes lung carcinoma to radiation Int. J. Nanomedicine 7 2012 2601 2611
    • (2012) Int. J. Nanomedicine , vol.7 , pp. 2601-2611
    • Shi, H.S.1
  • 24
    • 84867494034 scopus 로고    scopus 로고
    • Native and β-cyclodextrin-enclosed curcumin: Entrapment within liposomes and their in vitro cytotoxicity in lung and colon cancer
    • S. Rahman Native and β-cyclodextrin-enclosed curcumin: entrapment within liposomes and their in vitro cytotoxicity in lung and colon cancer Drug Deliv. 19 2012 346 353
    • (2012) Drug Deliv. , vol.19 , pp. 346-353
    • Rahman, S.1
  • 25
    • 84862807918 scopus 로고    scopus 로고
    • Liposome-encapsulated curcumin suppresses neuroblastoma growth through nuclear factor-kappa B inhibition
    • W.S. Orr Liposome-encapsulated curcumin suppresses neuroblastoma growth through nuclear factor-kappa B inhibition Surgery 151 2012 736 744
    • (2012) Surgery , vol.151 , pp. 736-744
    • Orr, W.S.1
  • 26
    • 84866782159 scopus 로고    scopus 로고
    • Inclusion complex of novel curcumin analogue CDF and β-cyclodextrin (1:2) and its enhanced in vivo anticancer activity against pancreatic cancer
    • P.R. Dandawate Inclusion complex of novel curcumin analogue CDF and β-cyclodextrin (1:2) and its enhanced in vivo anticancer activity against pancreatic cancer Pharm. Res. 29 2012 1775 1786
    • (2012) Pharm. Res. , vol.29 , pp. 1775-1786
    • Dandawate, P.R.1
  • 27
    • 84861646477 scopus 로고    scopus 로고
    • Antiglioma activity of curcumin-loaded lipid nanoparticles and its enhanced bioavailability in brain tissue for effective glioblastoma therapy
    • P. Kundu, C. Mohanty, and S.K. Sahoo Antiglioma activity of curcumin-loaded lipid nanoparticles and its enhanced bioavailability in brain tissue for effective glioblastoma therapy Acta Biomater. 8 2012 2670 2687
    • (2012) Acta Biomater. , vol.8 , pp. 2670-2687
    • Kundu, P.1    Mohanty, C.2    Sahoo, S.K.3
  • 28
    • 77953152280 scopus 로고    scopus 로고
    • Injectable sustained release microparticles of curcumin: A new concept for cancer chemoprevention
    • S. Komal Injectable sustained release microparticles of curcumin: a new concept for cancer chemoprevention Cancer Res. 70 2010 4443 4452
    • (2010) Cancer Res. , vol.70 , pp. 4443-4452
    • Komal, S.1
  • 29
    • 84870310484 scopus 로고    scopus 로고
    • Improving antiangiogenesis and anti-tumor activity of curcumin by biodegradable polymeric micelles
    • C. Gong Improving antiangiogenesis and anti-tumor activity of curcumin by biodegradable polymeric micelles Biomaterials 34 2013 1413 1432
    • (2013) Biomaterials , vol.34 , pp. 1413-1432
    • Gong, C.1
  • 30
    • 81255188940 scopus 로고    scopus 로고
    • Tumor angiogenesis: Molecular pathways and therapeutic targets
    • S.M. Weis, and D.A. Cheresh Tumor angiogenesis: molecular pathways and therapeutic targets Nat. Med. 17 2011 1359 1370
    • (2011) Nat. Med. , vol.17 , pp. 1359-1370
    • Weis, S.M.1    Cheresh, D.A.2
  • 31
    • 72949119124 scopus 로고    scopus 로고
    • Integrins in cancer: Biological implications and therapeutic opportunities
    • J.S. Desgrosellier, and D.A. Cheresh Integrins in cancer: biological implications and therapeutic opportunities Nat. Rev. Cancer 10 2010 9 22
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 9-22
    • Desgrosellier, J.S.1    Cheresh, D.A.2
  • 32
    • 84864125045 scopus 로고    scopus 로고
    • Peptides as targeting elements and tissue penetration devices for nanoparticles
    • E. Ruoslahti Peptides as targeting elements and tissue penetration devices for nanoparticles Adv. Mater. 24 2012 3747 3756
    • (2012) Adv. Mater. , vol.24 , pp. 3747-3756
    • Ruoslahti, E.1
  • 33
    • 81555224647 scopus 로고    scopus 로고
    • Integrin targeted delivery of chemotherapeutics
    • K. Chen, and X. Chen Integrin targeted delivery of chemotherapeutics Theranostics 1 2011 189 200
    • (2011) Theranostics , vol.1 , pp. 189-200
    • Chen, K.1    Chen, X.2
  • 34
    • 56749158194 scopus 로고    scopus 로고
    • Lipopeptide with a RGDK tetrapeptide sequence can selectively target genes to proangiogenic α5β1 integrin receptor and mouse tumor vasculature
    • D. Pramanik Lipopeptide with a RGDK tetrapeptide sequence can selectively target genes to proangiogenic α5β1 integrin receptor and mouse tumor vasculature J. Med. Chem. 51 2008 7298 7302
    • (2008) J. Med. Chem. , vol.51 , pp. 7298-7302
    • Pramanik, D.1
  • 35
    • 73249139451 scopus 로고    scopus 로고
    • The use of RGDGWK-lipopeptide to selectively deliver genes to mouse tumor vasculature and its complexation with p53 to inhibit tumor growth
    • S. Samanta, R. Sistla, and A. Chaudhuri The use of RGDGWK-lipopeptide to selectively deliver genes to mouse tumor vasculature and its complexation with p53 to inhibit tumor growth Biomaterials 31 2010 1787 1797
    • (2010) Biomaterials , vol.31 , pp. 1787-1797
    • Samanta, S.1    Sistla, R.2    Chaudhuri, A.3
  • 36
    • 45849083928 scopus 로고    scopus 로고
    • Evaluation of a nanotechnology based carrier for delivery of curcumin in prostate cancer cells
    • R.L. Thangapazham Evaluation of a nanotechnology based carrier for delivery of curcumin in prostate cancer cells Int. J. Oncol. 32 2008 1119 1123
    • (2008) Int. J. Oncol. , vol.32 , pp. 1119-1123
    • Thangapazham, R.L.1
  • 37
    • 0035174504 scopus 로고    scopus 로고
    • Phase i clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions
    • A.L. Cheng Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions Anticancer. Res. 21 2001 2895 2900
    • (2001) Anticancer. Res. , vol.21 , pp. 2895-2900
    • Cheng, A.L.1
  • 39
    • 53449094405 scopus 로고    scopus 로고
    • Anticancer and carcinogenic properties of curcumin: Considerations for its clinical development as a cancer chemopreventive and chemotherapeutic agent
    • M. Lopez-Lazaro Anticancer and carcinogenic properties of curcumin: considerations for its clinical development as a cancer chemopreventive and chemotherapeutic agent Mol. Nutr. Food Res. 52 Suppl. 1 2008 S103 S127
    • (2008) Mol. Nutr. Food Res. , vol.52 , Issue.SUPPL. 1
    • Lopez-Lazaro, M.1
  • 40
    • 0027315841 scopus 로고
    • Site-directed mutagenesis of the arginine-glycine-aspartic acid in vitronectin abolishes cell adhesion
    • R.C. Cherny, M.A. Honan, and P. Thiagarajan Site-directed mutagenesis of the arginine-glycine-aspartic acid in vitronectin abolishes cell adhesion J. Biol. Chem. 268 1993 9725 9729 (Pubitemid 23146033)
    • (1993) Journal of Biological Chemistry , vol.268 , Issue.13 , pp. 9725-9729
    • Cherny, R.C.1    Honan, M.A.2    Thiagarajan, P.3
  • 41
    • 16844373504 scopus 로고    scopus 로고
    • 1 integrin overexpressed on the luminal surface of tumor blood vessels
    • DOI 10.1158/0008-5472.CAN-04-2691
    • A. Magnussen Rapid access of antibodies to alpha5beta1 integrin overexpressed on the luminal surface of tumor blood vessels Cancer Res. 65 2005 2712 2721 (Pubitemid 40490072)
    • (2005) Cancer Research , vol.65 , Issue.7 , pp. 2712-2721
    • Magnussen, A.1    Kasman, I.M.2    Nerberg, S.3    Baluk, P.4    Murray, R.5    McDonald, D.M.6
  • 42
    • 84878666541 scopus 로고    scopus 로고
    • The relationship between the cyclic-RGDfK ligand and αvβ3 integrin receptor
    • G. Mondal, S. Barui, and A. Chaudhuri The relationship between the cyclic-RGDfK ligand and αvβ3 integrin receptor Biomaterials 34 2013 6249 6260
    • (2013) Biomaterials , vol.34 , pp. 6249-6260
    • Mondal, G.1    Barui, S.2    Chaudhuri, A.3
  • 43
    • 1942509594 scopus 로고    scopus 로고
    • Enhanced intravenous transgene expression in mouse lung using cyclic-head cationic lipids
    • M.K. Bharat Enhanced intravenous transgene expression in mouse lung using cyclic-head cationic lipids Chem. Biol. 11 2004 427 437
    • (2004) Chem. Biol. , vol.11 , pp. 427-437
    • Bharat, M.K.1
  • 44
    • 0033596121 scopus 로고    scopus 로고
    • Activators and target genes of Rel/NF-kappaB transcription factors
    • H.L. Pahl Activators and target genes of Rel/NF-kappaB transcription factors Oncogene 18 1999 6853 6866
    • (1999) Oncogene , vol.18 , pp. 6853-6866
    • Pahl, H.L.1
  • 45
    • 54349099181 scopus 로고    scopus 로고
    • Rapid reactive oxygen species (ROS) generation induced by curcumin leads to caspase-dependent and -independent apoptosis in L929 cells
    • F. Thayyullathil Rapid reactive oxygen species (ROS) generation induced by curcumin leads to caspase-dependent and -independent apoptosis in L929 cells Free Radic. Biol. Med. 45 2008 1403 1412
    • (2008) Free Radic. Biol. Med. , vol.45 , pp. 1403-1412
    • Thayyullathil, F.1
  • 46
    • 70249136561 scopus 로고    scopus 로고
    • Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model
    • A.B. Kunnumakkara Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model Int. J. Cancer 125 2009 2187 2197
    • (2009) Int. J. Cancer , vol.125 , pp. 2187-2197
    • Kunnumakkara, A.B.1
  • 47
    • 33847066381 scopus 로고    scopus 로고
    • The chemopreventive polyphenol curcumin prevents hematogenous breast cancer metastases in immunodeficient mice
    • B. Bachmeier, A.G. Nerlich, and C.M. Iancu The chemopreventive polyphenol curcumin prevents hematogenous breast cancer metastases in immunodeficient mice Cell. Physiol. Biochem. 19 2007 137 152
    • (2007) Cell. Physiol. Biochem. , vol.19 , pp. 137-152
    • Bachmeier, B.1    Nerlich, A.G.2    Iancu, C.M.3
  • 48
    • 27144468987 scopus 로고    scopus 로고
    • Curcumin suppresses the paclitaxel-induced nuclear factor-κB pathway in breast cancer cells and inhibits lung metastasis of human breast cancer in nude mice
    • DOI 10.1158/1078-0432.CCR-05-1192
    • B.B. Aggarwal Curcumin suppresses the paclitaxel-induced nuclear factor-κB pathway in breast cancer cells and inhibits lung metastasis of human breast cancer in nude mice Clin. Cancer Res. 11 2005 7490 7498 (Pubitemid 41507710)
    • (2005) Clinical Cancer Research , vol.11 , Issue.20 , pp. 7490-7498
    • Aggarwal, B.B.1    Shishodia, S.2    Takada, Y.3    Banerjee, S.4    Newman, R.A.5    Bueso-Ramos, C.E.6    Price, J.E.7
  • 49
    • 58149122747 scopus 로고    scopus 로고
    • Activated STAT3 is a mediator and biomarker of VEGF endothelial activation
    • S.H. Chen Activated STAT3 is a mediator and biomarker of VEGF endothelial activation Cancer Biol. Ther. 7 2008 1994-03
    • (2008) Cancer Biol. Ther. , vol.7 , pp. 1994-2003
    • Chen, S.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.