메뉴 건너뛰기




Volumn 2012, Issue , 2012, Pages

Salvianolic acid B inhibits ERK and p38 MAPK signaling in TGF-Β1-stimulated human hepatic stellate cell line (LX-2) via distinct pathways

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; SALVIANOLIC ACID B; SMAD PROTEIN; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 80053556610     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2012/960128     Document Type: Article
Times cited : (41)

References (23)
  • 1
    • 0033062807 scopus 로고    scopus 로고
    • Human and rat hepatic stellate cells produce stem cell factor: A possible mechanism for mast cell recruitment in liver fibrosis
    • DOI 10.1016/S0168-8278(99)80139-1
    • Gaa M. D. A., Pickering J. A., Arthur M. J. P., Benyon R. C., Human and rat hepatic stellate cells produce stem cell factor: a possible mechanism for mast cell recruitment in liver fibrosis Journal of Hepatology 1999 30 5 850 858 (Pubitemid 29248986)
    • (1999) Journal of Hepatology , vol.30 , Issue.5 , pp. 850-858
    • Gaca, M.D.A.1    Pickering, J.A.2    Arthur, M.J.P.3    Benyon, R.C.4
  • 2
    • 0036551274 scopus 로고    scopus 로고
    • Activation of hepatic stellate cellsa key issue in liver fibrosis
    • Reeves H. L., Friedman S. L., Activation of hepatic stellate cellsa key issue in liver fibrosis Frontiers in Bioscience 2002 7 d808 826
    • (2002) Frontiers in Bioscience , vol.7 , pp. 808-826
    • Reeves, H.L.1    Friedman, S.L.2
  • 3
    • 37149034101 scopus 로고    scopus 로고
    • Liver fibrosis: From mechanisms to treatment
    • DOI 10.1016/S0399-8320(07)73970-2
    • Friedman S. L., Liver fibrosis: from mechanisms to treatment Gastroenterologie Clinique et Biologique 2007 31 10 812 814 (Pubitemid 350261623)
    • (2007) Gastroenterologie Clinique et Biologique , vol.31 , Issue.10 , pp. 812-814
    • Friedman, S.L.1
  • 5
    • 11844250587 scopus 로고    scopus 로고
    • The role of TGF- 1 and cytokines in the modulation of liver fibrosis by Sho-saiko-to in rat's bile duct ligated model
    • Chen M. H., Chen J. C., Tsai C. C., Wang W. C., Chang D. C., Tu D. G., Hsieh H. Y., The role of TGF- 1 and cytokines in the modulation of liver fibrosis by Sho-saiko-to in rat's bile duct ligated model Journal of Ethnopharmacology 2005 97 1 7 13
    • (2005) Journal of Ethnopharmacology , vol.97 , Issue.1 , pp. 7-13
    • Chen, M.H.1    Chen, J.C.2    Tsai, C.C.3    Wang, W.C.4    Chang, D.C.5    Tu, D.G.6    Hsieh, H.Y.7
  • 8
    • 1342265526 scopus 로고    scopus 로고
    • Effects of salvianolic acid-B on TGF-beta 1 stimulated hepatic stellate cell activation and its intracellular signaling
    • Liu C., Liu P., Hu Y., Zhu D., Effects of salvianolic acid-B on TGF-beta 1 stimulated hepatic stellate cell activation and its intracellular signaling Zhonghua Yi Xue Za Zhi 2002 82 18 1267 1272
    • (2002) Zhonghua Yi Xue Za Zhi , vol.82 , Issue.18 , pp. 1267-1272
    • Liu, C.1    Liu, P.2    Hu, Y.3    Zhu, D.4
  • 10
    • 62749135921 scopus 로고    scopus 로고
    • Differential requirement for MEK/ERK and SMAD signaling in PAI-1 and CTGF expression in response to microtubule disruption
    • Samarakoon R., Higgins C. E., Higgins S. P., Higgins P. J., Differential requirement for MEK/ERK and SMAD signaling in PAI-1 and CTGF expression in response to microtubule disruption Cellular Signalling 2009 21 6 986 995
    • (2009) Cellular Signalling , vol.21 , Issue.6 , pp. 986-995
    • Samarakoon, R.1    Higgins, C.E.2    Higgins, S.P.3    Higgins, P.J.4
  • 11
    • 10844242987 scopus 로고    scopus 로고
    • Human hepatic stellate cell lines, LX-1 and LX-2: New tools for analysis of hepatic fibrosis
    • DOI 10.1136/gut.2004.042127
    • Xu L., Hui A. Y., Albanis E., Arthur M. J., O'Byrne S. M., Blaner W. S., Mukherjee P., Friedman S. L., Eng F. J., Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis Gut 2005 54 1 142 151 (Pubitemid 40007234)
    • (2005) Gut , vol.54 , Issue.1 , pp. 142-151
    • Xu, L.1    Hui, A.Y.2    Albanis, E.3    Arthur, M.J.4    O'Byrne, S.M.5    Blaner, W.S.6    Mukherjee, P.7    Friedman, S.L.8    Eng, F.J.9
  • 12
    • 78049382168 scopus 로고    scopus 로고
    • Effect of Salvianolic-acid B on inhibiting MAPK signaling induced by transforming growth factor- 1 in activated rat hepatic stellate cells
    • Lv Z., Song Y., Xue D., Zhang W., Cheng Y., Xu L., Effect of Salvianolic-acid B on inhibiting MAPK signaling induced by transforming growth factor- 1 in activated rat hepatic stellate cells Journal of Ethnopharmacology 2010 132 2 384 392
    • (2010) Journal of Ethnopharmacology , vol.132 , Issue.2 , pp. 384-392
    • Lv, Z.1    Song, Y.2    Xue, D.3    Zhang, W.4    Cheng, Y.5    Xu, L.6
  • 14
    • 44449122797 scopus 로고    scopus 로고
    • Transforming growth factor-β-induced alpha-smooth muscle cell actin expression in renal proximal tubular cells is regulated by p38β mitogen-activated protein kinase, extracellular signal-regulated protein kinase1,2 and the Smad signalling during epithelial-myofibroblast transdifferentiation
    • DOI 10.1093/ndt/gfm789
    • Sebe A., Leivonen S. K., Fintha A., Masszi A., Rosivall L., Khri V. M., Mucsi I., Transforming growth factor- -induced alpha-smooth muscle cell actin expression in renal proximal tubular cells is regulated by p38 mitogen-activated protein kinase, extracellular signal-regulated protein kinase1,2 and the Smad signalling during epithelial-myofibroblast transdifferentiation Nephrology Dialysis Transplantation 2008 23 5 1537 1545 (Pubitemid 351767730)
    • (2008) Nephrology Dialysis Transplantation , vol.23 , Issue.5 , pp. 1537-1545
    • Sebe, A.1    Leivonen, S.-K.2    Fintha, A.3    Masszi, A.4    Rosivall, L.5    Kahari, V.-M.6    Mucsi, I.7
  • 15
    • 0242456727 scopus 로고    scopus 로고
    • MAP inase modules: Many roads home
    • Raman M., Cobb M. H., MAP inase modules: many roads home Current Biology 2003 13 22 R886 R888
    • (2003) Current Biology , vol.13 , Issue.22
    • Raman, M.1    Cobb, M.H.2
  • 16
    • 0142026209 scopus 로고    scopus 로고
    • P38 MAP kinases: Key signalling molecules as therapeutic targets for inflammatory diseases
    • Kumar S., Boehm J., Lee J. C., P38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases Nature Reviews Drug Discovery 2003 2 9 717 726 (Pubitemid 37361787)
    • (2003) Nature Reviews Drug Discovery , vol.2 , Issue.9 , pp. 717-726
    • Kumar, S.1    Boehm, J.2    Lee, J.C.3
  • 20
    • 0035957924 scopus 로고    scopus 로고
    • Transcriptional cross-talk between smad, ERK1/2, and p38 Mitogen-activated protein kinase pathways regulates transforming growth factor- -induced aggrecan gene expression in chondrogenic ATDC5 cells
    • Watanabe H., de Caestecker M. P., Yamada Y., Transcriptional cross-talk between smad, ERK1/2, and p38 Mitogen-activated protein kinase pathways regulates transforming growth factor- -induced aggrecan gene expression in chondrogenic ATDC5 cells Journal of Biological Chemistry 2001 276 17 14466 14473
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.17 , pp. 14466-14473
    • Watanabe, H.1    De Caestecker, M.P.2    Yamada, Y.3
  • 21
    • 0034023127 scopus 로고    scopus 로고
    • Role of Ras and Mapks in TGFβ signaling
    • DOI 10.1016/S1359-6101(99)00026-X, PII S135961019900026X
    • Mulder K. M., Role of ras and mapks in TGF signaling Cytokine and Growth Factor Reviews 2000 11 1-2 23 35 (Pubitemid 30169723)
    • (2000) Cytokine and Growth Factor Reviews , vol.11 , Issue.1-2 , pp. 23-35
    • Mulder, K.M.1
  • 22
    • 33748799132 scopus 로고    scopus 로고
    • ERK contributes to the effects of Smad signaling on oxidized LDL-induced PAI-1 expression in human mesangial cells
    • DOI 10.1016/j.trsl.2006.07.005, PII S1931524406002957
    • Hong H. K., Song C. Y., Kim B. C., Lee H. S., ERK contributes to the effects of Smad signaling on oxidized LDL-induced PAI-1 expression in human mesangial cells Translational Research 2006 148 4 171 179 (Pubitemid 44416362)
    • (2006) Translational Research , vol.148 , Issue.4 , pp. 171-179
    • Hong, H.K.1    Song, C.Y.2    Kim, B.C.3    Lee, H.S.4
  • 23
    • 0037177841 scopus 로고    scopus 로고
    • Cross-talk between ERK and p38 MAPK mediates selective suppression of pro-inflammatory cytokines by transforming growth factor-β
    • DOI 10.1074/jbc.M111718200
    • Xiao Y. Q., Malcolm K., Worthen G. S., Gardai S., Schiemann W. P., Fadok V. A., Bratton D. L., Henson P. M., Cross-talk between ERK and p38 MAPK mediates selective suppression of pro-inflammatory cytokines by transforming growth factor- Journal of Biological Chemistry 2002 277 17 14884 14893 (Pubitemid 34952562)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.17 , pp. 14884-14893
    • Xiao, Y.Q.1    Malcolm, K.2    Scott Worthen, G.3    Gardai, S.4    Schiemann, W.P.5    Fadok, V.A.6    Bratton, D.L.7    Henson, P.M.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.