Bioavailability of salvianolic acid B and effect on blood viscosities after oral administration of salvianolic acids in beagle dogs

Archives of Pharmacal Research

Volumn 32, Issue 5, 2009, Pages 773-779

  Gao, Dong Yan ^a   Han, Li Mei ^a   Zhang, Li Hong ^b   Fang, Xiao Ling ^a   Wang, Jian Xin ^a  

^a FUDAN UNIVERSITY   (China)

^b TONGJI UNIVERSITY   (China)

Author keywords

Beagle dogs; Bioavailability; Blood viscosity; Salvianolic acid B; Salvianolic acids

Indexed keywords

3 (3,4 DIHYDROXYPHENYL)LACTIC ACID; DRUG METABOLITE; LITHOSPERMIC ACID; PROTOCATECHUALDEHYDE; SALVIANOLIC ACID B; BENZOFURAN DERIVATIVE; HERBACEOUS AGENT;

ACCURACY; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD VISCOSITY; CONTROLLED STUDY; DISTRIBUTION VOLUME; DOG; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG ELIMINATION; DRUG HALF LIFE; ELUTION; HERBAL MEDICINE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; NONHUMAN; PHARMACODYNAMICS; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION; ANIMAL; BIOAVAILABILITY; BIOTRANSFORMATION; BLOOD; BLOOD RHEOLOGY; DRUG EFFECT; INTRAVENOUS DRUG ADMINISTRATION; ORAL DRUG ADMINISTRATION; REPRODUCIBILITY; ULTRAVIOLET SPECTROPHOTOMETRY; VALIDATION STUDY;

ADMINISTRATION, ORAL; ANIMALS; AREA UNDER CURVE; BENZOFURANS; BIOLOGICAL AVAILABILITY; BIOTRANSFORMATION; BLOOD VISCOSITY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOGS; DRUGS, CHINESE HERBAL; HEMORHEOLOGY; INJECTIONS, INTRAVENOUS; MALE; REPRODUCIBILITY OF RESULTS; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 67649304834     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-009-1517-2     Document Type: Article

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