-
2
-
-
33646248661
-
Arf gene loss enhances oncogenicity and limits imatinib response in mouse models of Bcr-Abl-induced acute lymphoblastic leukemia
-
Williams RT, Roussel MF and Sherr CJ: Arf gene loss enhances oncogenicity and limits imatinib response in mouse models of Bcr-Abl-induced acute lymphoblastic leukemia. Proc Natl Acad Sci USA 103: 6688-6693, 2006.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 6688-6693
-
-
Williams, R.T.1
Roussel, M.F.2
Sherr, C.J.3
-
3
-
-
15044346433
-
BCR-ABL-transduced human cord blood cells produce abnormal populations in immunodeficient mice
-
DOI 10.1038/sj.leu.2403650
-
Chalandon Y, Jiang X, Christ O, Loutet S, Thanopoulou E, Eaves A and Eaves C: BCR-ABL-transduced human cord blood cells produce abnormal populations in immunodeficient mice. Leukemia 19: 442-448, 2005. (Pubitemid 40403323)
-
(2005)
Leukemia
, vol.19
, Issue.3
, pp. 442-448
-
-
Chalandon, Y.1
Jiang, X.2
Christ, O.3
Loutet, S.4
Thanopoulou, E.5
Eaves, A.6
Eaves, C.7
-
4
-
-
55749102434
-
Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: Implications for a new mechanism of resistance
-
Iacobucci I, Lonetti A, Messa F, Cilloni D, Arruga F, Ottaviani E, Paolini S, Papayannidis C, Piccaluga PP, Giannoulia P, Soverini S, Amabile M, Poerio A, Saglio G, Pane F, Berton G, Baruzzi A, Vitale A, Chiaretti S, Perini G, Foà R, Baccarani M and Martinelli G: Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: implications for a new mechanism of resistance. Blood 112: 3847-3855, 2008.
-
(2008)
Blood
, vol.112
, pp. 3847-3855
-
-
Iacobucci, I.1
Lonetti, A.2
Messa, F.3
Cilloni, D.4
Arruga, F.5
Ottaviani, E.6
Paolini, S.7
Papayannidis, C.8
Piccaluga, P.P.9
Giannoulia, P.10
Soverini, S.11
Amabile, M.12
Poerio, A.13
Saglio, G.14
Pane, F.15
Berton, G.16
Baruzzi, A.17
Vitale, A.18
Chiaretti, S.19
Perini, G.20
Foà, R.21
Baccarani, M.22
Martinelli, G.23
more..
-
5
-
-
0033566987
-
Decreases in Ikaros activity correlate with blast crisis in patients with chronic myelogenous leukemia
-
Nakayama H, Ishimaru F, Avitahl N, Sezaki N, Fujii N, Nakase K, Ninomiya Y, Harashima A, Minowada J, Tsuchiyama J, Imajoh K, Tsubota T, Fukuda S, Sezaki T, Kojima K, Hara M, Takimoto H, Yorimitsu S, Takahashi I, Miyata A, Taniguchi S, Tokunaga Y, Gondo H, Niho Y, Nakao S, Kyo T, Dohy H, Kamada N and Harada M: Decreases in Ikaros activity correlate with blast crisis in patients with chronic myelogenous leukemia. Cancer Res 59: 3931-3934, 1999. (Pubitemid 29393556)
-
(1999)
Cancer Research
, vol.59
, Issue.16
, pp. 3931-3934
-
-
Nakayama, H.1
Ishimaru, F.2
Avitahl, N.3
Sezaki, N.4
Fujii, N.5
Nakase, K.6
Ninomiya, Y.7
Harashima, A.8
Minowada, J.9
Tsuchiyama, J.10
Imajoh, K.11
Tsubota, T.12
Fukuda, S.13
Sezaki, T.14
Kojima, K.15
Hara, M.16
Takimoto, H.17
Yorimitsu, S.18
Takahashi, I.19
Miyata, A.20
Taniguchi, S.21
Tokunaga, Y.22
Gondo, H.23
Niho, Y.24
Nakao, S.25
Kyo, T.26
Dohy, H.27
Kamada, N.28
Harada, M.29
more..
-
6
-
-
0033870658
-
Dominant negative isoform of the Ikaros gene in patients with adult B-cell acute lymphoblastic leukemia
-
Nakase K, Ishimaru F, Avitahl N, Dansako H, Matsuo K, Fujii K, Sezaki N, Nakayama H, Yano T, Fukuda S, Imajoh K, Takeuchi M, Miyata A, Hara M, Yasukawa M, Takahashi I, Taguchi H, Matsue K, Nakao S, Niho Y, Takenaka K, Shinagawa K, Ikeda K, Niiya K and Harada M: Dominant negative isoform of the Ikaros gene in patients with adult B-cell acute lymphoblastic leukemia. Cancer Res 60: 4062-4065, 2000. (Pubitemid 30636585)
-
(2000)
Cancer Research
, vol.60
, Issue.15
, pp. 4062-4065
-
-
Nakase, K.1
Ishimaru, F.2
Avitahl, N.3
Dansako, H.4
Matsuo, K.5
Fujii, K.6
Sezaki, N.7
Nakayama, H.8
Yano, T.9
Fukuda, S.10
Imajoh, K.11
Takeuchi, M.12
Miyata, A.13
Hara, M.14
Yasukawa, M.15
Takahashi, I.16
Taguchi, H.17
Matsue, K.18
Nakao, S.19
Niho, Y.20
Takenaka, K.21
Shinagawa, K.22
Ikeda, K.23
Niiya, K.24
Harada, M.25
more..
-
7
-
-
0036045383
-
Non-DNA-binding Ikaros isoform gene expressed in adult B-precursor acute lymphoblastic leukemia
-
Nishii K, Katayama N, Miwa H, Shikami M, Usui E, Masuya M, Araki H, Lorenzo F, Ogawa T, Kyo T, Nasu K, Shiku H and Kita K: Non-DNA-binding Ikaros isoform gene expressed in adult B-precursor acute lymphoblastic leukemia. Leukemia 16: 1285-1292, 2002.
-
(2002)
Leukemia
, vol.16
, pp. 1285-1292
-
-
Nishii, K.1
Katayama, N.2
Miwa, H.3
Shikami, M.4
Usui, E.5
Masuya, M.6
Araki, H.7
Lorenzo, F.8
Ogawa, T.9
Kyo, T.10
Nasu, K.11
Shiku, H.12
Kita, K.13
-
8
-
-
0026451087
-
Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment
-
Georgopoulos K, Moore DD and Derfler B: Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment. Science 258: 808-812, 1992.
-
(1992)
Science
, vol.258
, pp. 808-812
-
-
Georgopoulos, K.1
Moore, D.D.2
Derfler, B.3
-
9
-
-
0028001362
-
The Ikaros gene is required for the development of all lymphoid lineages
-
DOI 10.1016/0092-8674(94)90407-3
-
Georgopoulos K, Bigby M, Wang JH, Molnar A, Wu P, Winandy S and Sharpe A: The Ikaros gene is required for the development of all lymphoid lineages. Cell 79: 143-156, 1994. (Pubitemid 24309520)
-
(1994)
Cell
, vol.79
, Issue.1
, pp. 143-156
-
-
Georgopoulos, K.1
Bigby, M.2
Wang, J.-H.3
Molnar, A.4
Wu, P.5
Winandy, S.6
Sharpe, A.7
-
10
-
-
0035525762
-
+ cells impairs their ability to differentiate toward the B-lymphoid lineage
-
+ cells impairs their ability to differentiate toward the B-lymphoid lineage. Blood 98: 2673-2680, 2001.
-
(2001)
Blood
, vol.98
, pp. 2673-2680
-
-
Tonnelle, C.1
Bardin, F.2
Maroc, C.3
Imbert, A.-M.4
Campa, F.5
Dalloul, A.6
Schmitt, C.7
Chabannon, C.8
-
11
-
-
0030498975
-
Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation
-
DOI 10.1016/S1074-7613(00)80269-1
-
Wang JH, Nichogiannopoulou A, Wu L, Sun L, Sharpe AH, Bigby M and Georgopoulos K: Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation. Immunity 5: 537-549, 1996. (Pubitemid 27062064)
-
(1996)
Immunity
, vol.5
, Issue.6
, pp. 537-549
-
-
Wang, J.-H.1
Nichogiannopoulou, A.2
Wu, L.3
Sun, L.4
Sharpe, A.H.5
Bigby, M.6
Georgopoulos, K.7
-
12
-
-
0028866897
-
A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma
-
Winandy S, Wu P and Georgopoulos K: A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma. Cell 83: 289-299, 1995.
-
(1995)
Cell
, vol.83
, pp. 289-299
-
-
Winandy, S.1
Wu, P.2
Georgopoulos, K.3
-
13
-
-
0030044364
-
The Ikaros gene encodes a family of lymphocyte-restricted zinc finger DNA binding proteins, highly conserved in human and mouse
-
Molnár A, Wu P, Largespada DA, Vortkamp A, Scherer S, Copeland NG, Jenkins NA, Bruns G and Georgopoulos K: The Ikaros gene encodes a family of lymphocyte-restricted zinc finger DNA binding proteins, highly conserved in human and mouse. J Immunol 156: 585-592, 1996. (Pubitemid 26028917)
-
(1996)
Journal of Immunology
, vol.156
, Issue.2
, pp. 585-592
-
-
Molnar, A.1
Wu, P.2
Largespada, D.A.3
Vortkamp, A.4
Scherer, S.5
Copeland, N.G.6
Jenkins, N.A.7
Bruns, G.8
Georgopoulos, K.9
-
14
-
-
0029831978
-
Zinc finger-mediated protein interactions modulate lkaros activity, a molecular control of lymphocyte development
-
Sun L, Liu A and Georgopoulos K: Zinc finger-mediated protein interactions modulate Ikaros acitivity, a molecular control of lymphocyte development. EMBO J 15: 5358-5369, 1996. (Pubitemid 26336218)
-
(1996)
EMBO Journal
, vol.15
, Issue.19
, pp. 5358-5369
-
-
Sun, L.1
Liu, A.2
Georgopoulos, K.3
-
15
-
-
49749114048
-
The Ikaros splice isoform, Ikaros 6, immortalizes murine haematopoietic progenitor cells
-
Ruiz A, Williams O and Brady HJ: The Ikaros splice isoform, Ikaros 6, immortalizes murine haematopoietic progenitor cells. Int J Cancer 123: 1240-1245, 2008.
-
(2008)
Int J Cancer
, vol.123
, pp. 1240-1245
-
-
Ruiz, A.1
Williams, O.2
Brady, H.J.3
-
16
-
-
43049139905
-
BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros
-
DOI 10.1038/nature06866, PII NATURE06866
-
Mullighan CG, Miller CB, Radtke I, Phillips LA, Dalton J, Ma J, White D, Hughes TP, Le Beau MM, Pui CH, Relling MV, Shurtleff SA and Downing JR: BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros. Nature 453: 110-114, 2008. (Pubitemid 351630327)
-
(2008)
Nature
, vol.453
, Issue.7191
, pp. 110-114
-
-
Mullighan, C.G.1
Miller, C.B.2
Radtke, I.3
Phillips, L.A.4
Dalton, J.5
Ma, J.6
White, D.7
Hughes, T.P.8
Le, B.M.M.9
Pui, C.-H.10
Relling, M.V.11
Shurtleff, S.A.12
Downing, J.R.13
-
17
-
-
70349242044
-
Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCR-ABL1-positive acute lymphoblastic leukemia patients: On behalf of Gruppo Italiano Malattie Ematologiche dell'Adulto Acute Leukemia Working Party (GIMEMA AL WP)
-
Iacobucci I, Storlazzi CT, Cilloni D, Lonetti A, Ottaviani E, Soverini S, Astolfi A, Chiaretti S, Vitale A, Messa F, Impera L, Baldazzi C, D'Addabbo P, Papayannidis C, Lonoce A, Colarossi S, Vignetti M, Piccaluga PP, Paolini S, Russo D, Pane F, Saglio G, Baccarani M, Foà R and Martinelli G: Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCR-ABL1-positive acute lymphoblastic leukemia patients: on behalf of Gruppo Italiano Malattie Ematologiche dell'Adulto Acute Leukemia Working Party (GIMEMA AL WP). Blood 114: 2159-2167, 2009.
-
(2009)
Blood
, vol.114
, pp. 2159-2167
-
-
Iacobucci, I.1
Storlazzi, C.T.2
Cilloni, D.3
Lonetti, A.4
Ottaviani, E.5
Soverini, S.6
Astolfi, A.7
Chiaretti, S.8
Vitale, A.9
Messa, F.10
Impera, L.11
Baldazzi, C.12
D'Addabbo, P.13
Papayannidis, C.14
Lonoce, A.15
Colarossi, S.16
Vignetti, M.17
Piccaluga, P.P.18
Paolini, S.19
Russo, D.20
Pane, F.21
Saglio, G.22
Baccarani, M.23
Foà, R.24
Martinelli, G.25
more..
-
18
-
-
77954609243
-
Haploinsufficiency of the IKZF1 (IKAROS) tumor suppressor gene cooperates with BCR-ABL in a transgenic model of acute lymphoblastic leukemia
-
Virely C, sMoulin S, Cobaleda C, Lasgi C, Alberdi A, Soulier J, Sigaux F, Chan S, Kastner P and Ghysdael J: Haploinsufficiency of the IKZF1 (IKAROS) tumor suppressor gene cooperates with BCR-ABL in a transgenic model of acute lymphoblastic leukemia. Leukemia 24: 1200-1204, 2010.
-
(2010)
Leukemia
, vol.24
, pp. 1200-1204
-
-
Virely, C.1
SMoulin, S.2
Cobaleda, C.3
Lasgi, C.4
Alberdi, A.5
Soulier, J.6
Sigaux, F.7
Chan, S.8
Kastner, P.9
Ghysdael, J.10
-
19
-
-
0037392235
-
Over-expression of the dominant-negative isoform of Ikaros confers resistance to dexamethasone-induced and anti-IgM-induced apoptosis
-
DOI 10.1046/j.1365-2141.2003.04263.x
-
Sezaki N, Ishimaru F, Takata M, Tabayashi T, Nakase K, Kozuka T, Fujii K, Nakayama H, Teshima T, Harada M and Tanimoto M: Over-expression of the dominant-negative isoform of Ikaros confers resistance to dexamethasone-induced and anti-IgM-induced apoptosis. Br J Haematol 121: 165-169, 2003. (Pubitemid 36461284)
-
(2003)
British Journal of Haematology
, vol.121
, Issue.1
, pp. 165-169
-
-
Sezaki, N.1
Ishimaru, F.2
Takata, M.3
Tabayashi, T.4
Nakase, K.5
Kozuka, T.6
Fujii, K.7
Nakayama, H.8
Teshima, T.9
Harada, M.10
Tanimoto, M.11
-
20
-
-
58749109707
-
Children's Oncology Group: Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia
-
Mullighan CG, Su X, Zhang J, Radtke I, Phillips LA, Miller CB, Ma J, Liu W, Cheng C, Schulman BA, Harvey RC, Chen IM, Clifford RJ, Carroll WL, Reaman G, Bowman WP, Devidas M, Gerhard DS, Yang W, Relling MV, Shurtleff SA, Campana D, Borowitz MJ, Pui CH, Smith M, Hunger SP, Willman CL and Downing JR, Children's Oncology Group: Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia. N Engl J Med 360: 470-480, 2009.
-
(2009)
N Engl J Med
, vol.360
, pp. 470-480
-
-
Mullighan, C.G.1
Su, X.2
Zhang, J.3
Radtke, I.4
Phillips, L.A.5
Miller, C.B.6
Ma, J.7
Liu, W.8
Cheng, C.9
Schulman, B.A.10
Harvey, R.C.11
Chen, I.M.12
Clifford, R.J.13
Carroll, W.L.14
Reaman, G.15
Bowman, W.P.16
Devidas, M.17
Gerhard, D.S.18
Yang, W.19
Relling, M.V.20
Shurtleff, S.A.21
Campana, D.22
Borowitz, M.J.23
Pui, C.H.24
Smith, M.25
Hunger, S.P.26
Willman, C.L.27
Downing, J.R.28
more..
-
21
-
-
70449719091
-
IKZF1 (Ikaros) deletions in BCR-ABL1-positive acute lymphoblastic leukemia are associated with short disease-free survival and high rate of cumulative incidence of relapse: A GIMEMA AL WP report
-
Martinelli G, Iacobucci I, Storlazzi CT, Vignetti M, Paoloni F, Cilloni D, Soverini S, Vitale A, Chiaretti S, Cimino G, Papayannidis C, Paolini S, Elia L, Fazi P, Meloni G, Amadori S, Saglio G, Pane F, Baccarani M and Foà R: IKZF1 (Ikaros) deletions in BCR-ABL1-positive acute lymphoblastic leukemia are associated with short disease-free survival and high rate of cumulative incidence of relapse: a GIMEMA AL WP report. J Clin Oncol 27: 5202-5207, 2009.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5202-5207
-
-
Martinelli, G.1
Iacobucci, I.2
Storlazzi, C.T.3
Vignetti, M.4
Paoloni, F.5
Cilloni, D.6
Soverini, S.7
Vitale, A.8
Chiaretti, S.9
Cimino, G.10
Papayannidis, C.11
Paolini, S.12
Elia, L.13
Fazi, P.14
Meloni, G.15
Amadori, S.16
Saglio, G.17
Pane, F.18
Baccarani, M.19
Foà, R.20
more..
-
22
-
-
0036565871
-
BCR-ABL activity in transduced primary human hematopoietic cells controls lineage programming
-
BCR-ABL activity in transduced primary human hematopoietic cells controls lineage programming. Blood 99: 3197-3204, 2002.
-
(2002)
Blood
, vol.99
, pp. 3197-3204
-
-
Chalandon, Y.1
Jiang, X.2
Hazlewood, G.3
Loutet, S.4
Conneally, E.5
Eaves, A.6
Eaves, C.7
-
23
-
-
59749084821
-
+ cells induces similar gene expression profiles and results in a STAT5-dependent expansion of the erythroid lineage
-
+ cells induces similar gene expression profiles and results in a STAT5-dependent expansion of the erythroid lineage. Exp Hematol 37: 367-375, 2009.
-
(2009)
Exp Hematol
, vol.37
, pp. 367-375
-
-
Järås, M.1
Johnels, P.2
Agerstam, H.3
Lassen, C.4
Rissler, M.5
Edén, P.6
Cammenga, J.7
Olofsson, T.8
Bjerrum, O.W.9
Richter, J.10
Fan, X.11
Fioretos, T.12
-
24
-
-
33748753239
-
Pleiotropic role of histone deacetylases in the regulation of human adult erythropoiesis
-
DOI 10.1111/j.1365-2141.2006.06275.x
-
Yamamura K, Ohishi K, Katayama N, Yu Z, Kato K, Masuya M, Fujieda A, Sugimoto Y, Miyata E, Shibasaki T, Heike Y, Takaue Y and Shiku H: Pleiotropic role of histone deacetylases in the regulation of human adult erythropoiesis. Br J Haematol 135: 242-253, 2006. (Pubitemid 44401623)
-
(2006)
British Journal of Haematology
, vol.135
, Issue.2
, pp. 242-253
-
-
Yamamura, K.1
Ohishi, K.2
Katayama, N.3
Yu, Z.4
Kato, K.5
Masuya, M.6
Fujieda, A.7
Sugimoto, Y.8
Miyata, E.9
Shibasaki, T.10
Heike, Y.11
Takaue, Y.12
Shiku, H.13
-
25
-
-
0037438385
-
Ex vivo expansion of human umbilical cord hematopoietic progenitor cells using a coculture system with human telomerase catalytic subunit (hTERT)-transfected human stromal cells
-
DOI 10.1182/blood-2002-04-1268
-
Kawano Y, Kobune M, Yamaguchi M, Nakamura K, Ito Y, Sasaki K, Takahashi S, Nakamura T, Chiba H, Sato T, Matsunaga T, Azuma H, Ikebuchi K, Ikeda H, Kato J, Niitsu Y and Hamada H: Ex vivo expansion of human umbilical cord hematopoietic progenitor cells using a coculture system with human telomerase catalytic subunit (hTERT)-transfected human stromal cells. Blood 101: 532-540, 2003. (Pubitemid 36077574)
-
(2003)
Blood
, vol.101
, Issue.2
, pp. 532-540
-
-
Kawano, Y.1
Kobune, M.2
Yamaguchi, M.3
Nakamura, K.4
Ito, Y.5
Sasaki, K.6
Takahashi, S.7
Nakamura, T.8
Chiba, H.9
Sato, T.10
Matsunaga, T.11
Azuma, H.12
Ikebuchi, K.13
Ikeda, H.14
Kato, J.15
Niitsu, Y.16
Hamada, H.17
-
26
-
-
0036320651
-
Pim-1 expression is sufficient to induce cytokine independence in murine hematopoietic cells, but is dispensable for BCR-ABL-mediated transformation
-
DOI 10.1016/S0301-472X(02)00808-1, PII S0301472X02008081
-
Nosaka T and Kitamuta T: Pim-1 expression is sufficient to induce cytokine independence in murine hematopoietic cells, but is dispensable for BCR-ABL-mediated transformation. Exp Hematol 30: 697-702, 2002. (Pubitemid 34831689)
-
(2002)
Experimental Hematology
, vol.30
, Issue.7
, pp. 697-702
-
-
Nosaka, T.1
Kitamura, T.2
-
27
-
-
0031836964
-
Identification and characterization of a constitutively active STAT5 mutant that promotes cell proliferation
-
Onishi M, Nosaka T, Misawa K, Mui ALF, Gorman D, McMahon M, Miyajima A and Kitamura T: Identification and characterization of a constitutively active STAT5 mutant that promotes cell proliferation. Mol Cell Biol 18: 3871-3879, 1998. (Pubitemid 28287910)
-
(1998)
Molecular and Cellular Biology
, vol.18
, Issue.7
, pp. 3871-3879
-
-
Onishi, M.1
Nosaka, T.2
Misawa, K.3
Mui, A.L.-F.4
Gorman, D.5
McMahon, M.6
Miyajima, A.7
Kitamura, T.8
-
28
-
-
0142227052
-
Retrovirus-mediated gene transfer and expression cloning: Powerful tools in functional genomics
-
DOI 10.1016/j.exphem.2003.07.005
-
Kitamura T, Koshino Y, Shibata F, Oki T, Nakajima H, Nosaka T and Kumagai H: Retrovirus-mediated gene transfer and expression cloning: powerful tools in functional genomics. Exp Hematol 31: 1007-1014, 2003. (Pubitemid 37329742)
-
(2003)
Experimental Hematology
, vol.31
, Issue.11
, pp. 1007-1014
-
-
Kitamura, T.1
Koshino, Y.2
Shibata, F.3
Oki, T.4
Nakajima, H.5
Nosaka, T.6
Kumagai, H.7
-
29
-
-
0020644732
-
1-positive human cell line (BV173)
-
Pegoraro L, Matera L, Ritz J, Levis A, Palumbo A and Biagini G: Establishment of a Ph1-positive human cell line (BV173). J Natl Cancer Inst 70: 447-453, 1983. (Pubitemid 13117191)
-
(1983)
Journal of the National Cancer Institute
, vol.70
, Issue.3
, pp. 447-453
-
-
Pegoraro, L.1
Matera, L.2
Ritz, J.3
-
30
-
-
74049101141
-
Mixed-lineage-leukemia (MLL) fusion protein collaborates with Ras to induce acute leukemia through aberrant Hox expression and Raf activation
-
Ono R, Kumagai H, Nakajima H, Hishiya A, Taki T, Horikawa K, Takatsu K, Satoh T, Hayashi Y, Kitamura T and Nosaka T: Mixed-lineage-leukemia (MLL) fusion protein collaborates with Ras to induce acute leukemia through aberrant Hox expression and Raf activation. Leukemia 23: 2197-2209, 2009.
-
(2009)
Leukemia
, vol.23
, pp. 2197-2209
-
-
Ono, R.1
Kumagai, H.2
Nakajima, H.3
Hishiya, A.4
Taki, T.5
Horikawa, K.6
Takatsu, K.7
Satoh, T.8
Hayashi, Y.9
Kitamura, T.10
Nosaka, T.11
-
31
-
-
16844380787
-
Dimerization of MLL fusion proteins and FLT3 activation synergize to induce multiple-lineage leukemogenesis
-
DOI 10.1172/JCI200522725
-
Ono R, Nakajima H, Ozaki K, Kumagai H. Kawashima T, Taki T, Kitamura T, Hayashi Y and Nosaka T: Dimerization of MLL fusion proteins and FLT3 activation synergize to induce multiple-lineage leukemogenesis. J Clin Invest 115: 919-929, 2005. (Pubitemid 40489396)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.4
, pp. 919-929
-
-
Ono, R.1
Nakajima, H.2
Ozaki, K.3
Kumagai, H.4
Kawashima, T.5
Taki, T.6
Kitamura, T.7
Hayashi, Y.8
Nosaka, T.9
-
32
-
-
0033199236
-
STAT5 as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cells
-
DOI 10.1093/emboj/18.17.4754
-
Nosaka T, Kawashima T, Misawa K, Ikuta K, Mui AL-F and Kitamura T: STAT5 as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cells. EMBO J 18: 4754-4765, 1999. (Pubitemid 29415529)
-
(1999)
EMBO Journal
, vol.18
, Issue.17
, pp. 4754-4765
-
-
Nosaka, T.1
Kawashima, T.2
Misawa, K.3
Ikuta, K.4
Mui, A.L.-F.5
Kitamura, T.6
-
33
-
-
68149098480
-
Pre-B cell receptor-mediated cell cycle arrest in Philadelphia chromosome-positive acute lymphoblastic leukemia requires IKAROS function
-
Trageser D, Iacobucci I, Nahar R, Duy C, von Levetzow G, Klemm L, Park E, Schuh W, Gruber T, Herzog S, Kim Y-M, Hofmann W-K, Li A, Storlazzi CT, Jäck H-M, Groffen J, Martinelli G, Heisterkamp N, Jumaa H and Müschen M: Pre-B cell receptor-mediated cell cycle arrest in Philadelphia chromosome-positive acute lymphoblastic leukemia requires IKAROS function. J Exp Med 206: 1739-1753, 2009.
-
(2009)
J Exp Med
, vol.206
, pp. 1739-1753
-
-
Trageser, D.1
Iacobucci, I.2
Nahar, R.3
Duy, C.4
Von Levetzow, G.5
Klemm, L.6
Park, E.7
Schuh, W.8
Gruber, T.9
Herzog, S.10
Kim, Y.-M.11
Hofmann, W.-K.12
Li, A.13
Storlazzi, C.T.14
Jäck, H.-M.15
Groffen, J.16
Martinelli, G.17
Heisterkamp, N.18
Jumaa, H.19
Müschen, M.20
more..
-
34
-
-
77954977940
-
Chronic myeloid leukemia: Mechanisms of blastic transformation
-
Perrotti D, Jamieson C, Goldman J and Skorski T: Chronic myeloid leukemia: mechanisms of blastic transformation. J Clin Invest 120: 2254-2264, 2010.
-
(2010)
J Clin Invest
, vol.120
, pp. 2254-2264
-
-
Perrotti, D.1
Jamieson, C.2
Goldman, J.3
Skorski, T.4
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