-
1
-
-
0002180797
-
Yeast cell wall and cell surface
-
eds. J. N. Strathern, E. W. Jones, and J. R. Broach, pp, Cold Spring Harbor, NY: Cold Spring Harbor Laboratory
-
Ballou, C. E. 1982. Yeast cell wall and cell surface. In The molecular biology of the yeast Saccharomyces, Metabolism and gene expression, eds. J. N. Strathern, E. W. Jones, and J. R. Broach, pp. 335-306. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
-
(1982)
The molecular biology of the yeast Saccharomyces, Metabolism and gene expression
, pp. 335-306
-
-
Ballou, C.E.1
-
2
-
-
0038558248
-
Dectin-1 mediates the biological effects of beta-glucans
-
Brown, G. D., Herre, J., Williams, D. L., Willment, J. A., Marshall, A. S., and Gordon, S. 2003. Dectin-1 mediates the biological effects of beta-glucans. J. Exp. Med. 197:1119-1124.
-
(2003)
J. Exp. Med
, vol.197
, pp. 1119-1124
-
-
Brown, G.D.1
Herre, J.2
Williams, D.L.3
Willment, J.A.4
Marshall, A.S.5
Gordon, S.6
-
3
-
-
0017890077
-
Glucan-activated macrophages: Functional characteristics and surface morphology
-
Burgaleta, C., Territo, M. C., Quan, S. G., and Golde, D. W. 1978. Glucan-activated macrophages: Functional characteristics and surface morphology. J. Reticuloendothel. Soc. 23:195-204.
-
(1978)
J. Reticuloendothel. Soc
, vol.23
, pp. 195-204
-
-
Burgaleta, C.1
Territo, M.C.2
Quan, S.G.3
Golde, D.W.4
-
4
-
-
0030744865
-
The impact of non-endotoxin lal-reactive materials on Limulus amebocyte lysate analyses
-
Cooper, J. F., Weary, M. E., and Jordan, F. T. 1997. The impact of non-endotoxin lal-reactive materials on Limulus amebocyte lysate analyses. PDA J. Pharm. Sci. Technol. 51:2-6.
-
(1997)
PDA J. Pharm. Sci. Technol
, vol.51
, pp. 2-6
-
-
Cooper, J.F.1
Weary, M.E.2
Jordan, F.T.3
-
5
-
-
0031689591
-
A new method for quantitative determination of polysaccharides in the yeast cell wall. Application to the cell wall defective mutants of saccharomyces cerevisiae
-
Dallies, N., Francois, J., and Paquet, V. 1998. A new method for quantitative determination of polysaccharides in the yeast cell wall. Application to the cell wall defective mutants of saccharomyces cerevisiae. Yeast 14:1297-1306.
-
(1998)
Yeast
, vol.14
, pp. 1297-1306
-
-
Dallies, N.1
Francois, J.2
Paquet, V.3
-
6
-
-
0026802893
-
Zymosan induces selective release of arachidonic acid from rabbit alveolar macrophage via stimulation of a beta-glucan receptor
-
Daum, T., and Rohrbach, M. S. 1992. Zymosan induces selective release of arachidonic acid from rabbit alveolar macrophage via stimulation of a beta-glucan receptor. FEBS Lett. 309, 119-122.
-
(1992)
FEBS Lett
, vol.309
, pp. 119-122
-
-
Daum, T.1
Rohrbach, M.S.2
-
7
-
-
0000701007
-
On the composition of zymosan
-
DiCarlo, F. J., and Fiore, J. V. 1957. On the composition of zymosan. Science 127:756-757.
-
(1957)
Science
, vol.127
, pp. 756-757
-
-
DiCarlo, F.J.1
Fiore, J.V.2
-
8
-
-
0018756121
-
Lysozyme, glucan-activated macrophages and neoplsia
-
Luzio, N. R. 1979. Lysozyme, glucan-activated macrophages and neoplsia. J. Reticuloendothel. Soc. 26:67-81.
-
(1979)
J. Reticuloendothel. Soc
, vol.26
, pp. 67-81
-
-
Luzio, N.R.1
-
9
-
-
34250191149
-
-
Domer, J., and Garner, R. 1990. Fungal wall components and immunostimulation. In Fungal cell wall and immune response, J.-P. Latge and D. Boucias, pp. 415-430. Berlin: Springer-Verlag.
-
Domer, J., and Garner, R. 1990. Fungal wall components and immunostimulation. In Fungal cell wall and immune response, J.-P. Latge and D. Boucias, pp. 415-430. Berlin: Springer-Verlag.
-
-
-
-
10
-
-
0031218392
-
Cytokines and particle-induced inflammatory cell recruitment
-
Driscoll, K. E., Carter, J. M., Hassenbein, D. G., and Howard, B. 1997. Cytokines and particle-induced inflammatory cell recruitment. Environ. Health Perspect. 105(suppl. 5):1159-1164.
-
(1997)
Environ. Health Perspect
, vol.105
, Issue.SUPPL. 5
, pp. 1159-1164
-
-
Driscoll, K.E.1
Carter, J.M.2
Hassenbein, D.G.3
Howard, B.4
-
11
-
-
3142592636
-
Modification of the Limulus amebocyte lysate assay for the analysis of glucan in indoor environments
-
Foto, M., Plett, J., Berghout, J., and Miller, J. D. 2004. Modification of the Limulus amebocyte lysate assay for the analysis of glucan in indoor environments. Anal. Bioanal. Chem. 379:156-162.
-
(2004)
Anal. Bioanal. Chem
, vol.379
, pp. 156-162
-
-
Foto, M.1
Plett, J.2
Berghout, J.3
Miller, J.D.4
-
12
-
-
22044448235
-
Role of mannose receptor in oligochitosan-mediated stimulation of macrophage function
-
Han, Y., Zhao, L., Yu, Z., Feng, J., and Yu, Q. 2005. Role of mannose receptor in oligochitosan-mediated stimulation of macrophage function. Int. Immunopharmacol. 5:1533-1542.
-
(2005)
Int. Immunopharmacol
, vol.5
, pp. 1533-1542
-
-
Han, Y.1
Zhao, L.2
Yu, Z.3
Feng, J.4
Yu, Q.5
-
13
-
-
0029179304
-
Composition of plant cell walls
-
Heredia, A., Jimenez, A., and Guillen, R. 1995. Composition of plant cell walls. Z. Lebensm. Unters. Forsch. 200:24-31.
-
(1995)
Z. Lebensm. Unters. Forsch
, vol.200
, pp. 24-31
-
-
Heredia, A.1
Jimenez, A.2
Guillen, R.3
-
14
-
-
0033456234
-
Nitric oxide and proinflammatory cytokines in nasal lavage fluid associated with symptoms and exposure to moldy building microbes
-
Hirvonen, M. R., Ruotsalainen, M., Roponen, M., Hyvarinen, A., Husman, T., Kosma, V. M., Komulainen, H., Savolainen, K., and Nevalainen, A. 1999. Nitric oxide and proinflammatory cytokines in nasal lavage fluid associated with symptoms and exposure to moldy building microbes. Am. J. Respir. Crit. Care Med. 160:1943-1946.
-
(1999)
Am. J. Respir. Crit. Care Med
, vol.160
, pp. 1943-1946
-
-
Hirvonen, M.R.1
Ruotsalainen, M.2
Roponen, M.3
Hyvarinen, A.4
Husman, T.5
Kosma, V.M.6
Komulainen, H.7
Savolainen, K.8
Nevalainen, A.9
-
15
-
-
0024596406
-
Airborne endotoxins: An association with occupational lung disease
-
Jacobs, R. R. 1989. Airborne endotoxins: An association with occupational lung disease. Appl. Ind. Hyg. 4:50-56.
-
(1989)
Appl. Ind. Hyg
, vol.4
, pp. 50-56
-
-
Jacobs, R.R.1
-
16
-
-
0036907167
-
Spores of aspergillus versicolor isolated from indoor air of a moisture-damaged building provoke acute inflammation in mouse lungs
-
Jussila, J., Komulainen, H., Kosma, V. M., Nevalainen, A., Pelkonen, J., and Hirvonen, M. R. 2002. Spores of aspergillus versicolor isolated from indoor air of a moisture-damaged building provoke acute inflammation in mouse lungs. Inhal. Toxicol. 14:1261-1277.
-
(2002)
Inhal. Toxicol
, vol.14
, pp. 1261-1277
-
-
Jussila, J.1
Komulainen, H.2
Kosma, V.M.3
Nevalainen, A.4
Pelkonen, J.5
Hirvonen, M.R.6
-
17
-
-
0028897101
-
Architecture of the yeast cell wall. The linkage between chitin and beta(1 - >3)-glucan
-
Kollar, R., Petrakova, E., Ashwell, G., Robbins, P. W., and Cabib, E. 1995. Architecture of the yeast cell wall. The linkage between chitin and beta(1 - >3)-glucan. J. Biol. Chem. 270:1170-1178.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 1170-1178
-
-
Kollar, R.1
Petrakova, E.2
Ashwell, G.3
Robbins, P.W.4
Cabib, E.5
-
18
-
-
0030814079
-
Architecture of the yeast cell wall. Beta(1 - >6)-glucan interconnects mannoprotein, beta(1 - >)3-glucan, and chitin
-
Kollar, R., Reinhold, B. B., Petrakova, E., Yeh, H. J., Ashwell, G., Drgonova, J., Kapteyn, J. C., Klis, F. M., and Cabib, E. 1997. Architecture of the yeast cell wall. Beta(1 - >6)-glucan interconnects mannoprotein, beta(1 - >)3-glucan, and chitin. J. Biol. Chem. 272:17762-17775.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 17762-17775
-
-
Kollar, R.1
Reinhold, B.B.2
Petrakova, E.3
Yeh, H.J.4
Ashwell, G.5
Drgonova, J.6
Kapteyn, J.C.7
Klis, F.M.8
Cabib, E.9
-
19
-
-
0346336124
-
Pneumocystis carinii: Cell wall beta-glucan-mediated pulmonary inflammation
-
Limper, A. H., Lebron, F., Evans, S. E., and Hahn, R. Y. 2003. Pneumocystis carinii: Cell wall beta-glucan-mediated pulmonary inflammation. J. Eukaryot. Microbiol. 50(suppl.):646.
-
(2003)
J. Eukaryot. Microbiol
, vol.50
, Issue.SUPPL.
, pp. 646
-
-
Limper, A.H.1
Lebron, F.2
Evans, S.E.3
Hahn, R.Y.4
-
20
-
-
0025314534
-
Endotoxin measurement: Aerosol sampling and application of a new limulus method
-
Milton, D. K., Gere, R. J., Feldman, H. A., and Greaves, I. A. 1990. Endotoxin measurement: Aerosol sampling and application of a new limulus method. Am. Ind. Hyg. Assoc. J. 51:331-337.
-
(1990)
Am. Ind. Hyg. Assoc. J
, vol.51
, pp. 331-337
-
-
Milton, D.K.1
Gere, R.J.2
Feldman, H.A.3
Greaves, I.A.4
-
21
-
-
0026514698
-
Environmental endotoxin measurement: The kinetic Limulus assay with resistant-parallel-line estimation
-
Milton, D. K., Feldman, H. A., Neuberg, D. S., Bruckner, R. J., and Greaves, I. A. 1992. Environmental endotoxin measurement: The kinetic Limulus assay with resistant-parallel-line estimation. Environ. Res. 57:212-230.
-
(1992)
Environ. Res
, vol.57
, pp. 212-230
-
-
Milton, D.K.1
Feldman, H.A.2
Neuberg, D.S.3
Bruckner, R.J.4
Greaves, I.A.5
-
22
-
-
34250170886
-
Comparison of various LAL methods
-
Novitsky, T. J. 1993. Comparison of various LAL methods. LAL Update 11:2-4.
-
(1993)
LAL Update
, vol.11
, pp. 2-4
-
-
Novitsky, T.J.1
-
23
-
-
0034666005
-
The fungal cell wall component beta-1,3-glucan has an adjuvant effect on the allergic response to ovalbumin in mice
-
Ormstad, H., Groeng, E.-C., Lovik, M., and Hetland, G. 2000. The fungal cell wall component beta-1,3-glucan has an adjuvant effect on the allergic response to ovalbumin in mice. J. Toxicol. Environ. Health A 61:55-67.
-
(2000)
J. Toxicol. Environ. Health A
, vol.61
, pp. 55-67
-
-
Ormstad, H.1
Groeng, E.-C.2
Lovik, M.3
Hetland, G.4
-
24
-
-
0042623422
-
Efficacy of a technique for exposing the mouse lung to particles aspirated from the pharynx
-
Rao, G. V., Tinkle, S., Weissman, D. N., Antonini, J. M., Kashon, M. L., Salmen, R., Battelli, L. A., Willard, P. A., Hoover, M. D., and Hubbs, A. F. 2003. Efficacy of a technique for exposing the mouse lung to particles aspirated from the pharynx. J. Toxicol. Environ. Health A 66:1441-1452.
-
(2003)
J. Toxicol. Environ. Health A
, vol.66
, pp. 1441-1452
-
-
Rao, G.V.1
Tinkle, S.2
Weissman, D.N.3
Antonini, J.M.4
Kashon, M.L.5
Salmen, R.6
Battelli, L.A.7
Willard, P.A.8
Hoover, M.D.9
Hubbs, A.F.10
-
25
-
-
0023077050
-
Specificity of membrane complement receptor type three (cr3) for beta-glucans
-
Ross, G. D., Cain, J. A., Myones, B. L., Newman, S. L., and Lachmann, P. J. 1987. Specificity of membrane complement receptor type three (cr3) for beta-glucans. Complement 4:61-74.
-
(1987)
Complement
, vol.4
, pp. 61-74
-
-
Ross, G.D.1
Cain, J.A.2
Myones, B.L.3
Newman, S.L.4
Lachmann, P.J.5
-
27
-
-
0032791064
-
Indoor air-related effects and airborne (1 - > 3)-beta-d-glucan
-
Rylander, R. 1999. Indoor air-related effects and airborne (1 - > 3)-beta-d-glucan. Environ. Health Perspect. 107(suppl. 3):501-503.
-
(1999)
Environ. Health Perspect
, vol.107
, Issue.SUPPL. 3
, pp. 501-503
-
-
Rylander, R.1
-
28
-
-
0029101735
-
Effect of soluble fungi (1-3)-beta-d-glucan obtained from sclerotinia sclerotiorum on macrophage activation
-
Sakurai, T., Ohno, N., Suzuki, I., and Yadomae, T. 1995. Effect of soluble fungi (1-3)-beta-d-glucan obtained from sclerotinia sclerotiorum on macrophage activation. Immunopharmacology 30:157-166.
-
(1995)
Immunopharmacology
, vol.30
, pp. 157-166
-
-
Sakurai, T.1
Ohno, N.2
Suzuki, I.3
Yadomae, T.4
-
29
-
-
0032571026
-
Effect of glucan on murine lungs
-
Schuyler, M., Gott, K., and Cherne, A. 1998. Effect of glucan on murine lungs. J. Toxicol. Environ. Health A 53:493-505.
-
(1998)
J. Toxicol. Environ. Health A
, vol.53
, pp. 493-505
-
-
Schuyler, M.1
Gott, K.2
Cherne, A.3
-
30
-
-
0022919831
-
Glucan stimulates production of antitumor cytolytic/cytosatic factor(s) by macrophages
-
Sherwood, E. R., Williams, D. L., and Di Luzio, N. R. 1986. Glucan stimulates production of antitumor cytolytic/cytosatic factor(s) by macrophages. J. Biol. Response Mod. 5:504-526.
-
(1986)
J. Biol. Response Mod
, vol.5
, pp. 504-526
-
-
Sherwood, E.R.1
Williams, D.L.2
Di Luzio, N.R.3
-
31
-
-
0033178781
-
Cell wall dynamics in yeast
-
Smits, G. J., Kapteyn, J. C., van den Ende, H., and Klis, F. M. 1999. Cell wall dynamics in yeast. Curr. Opin. Microbiol. 2:348-352.
-
(1999)
Curr. Opin. Microbiol
, vol.2
, pp. 348-352
-
-
Smits, G.J.1
Kapteyn, J.C.2
van den Ende, H.3
Klis, F.M.4
-
32
-
-
0001017560
-
Beta-1,3-glucan enhancement of protease activity in crayfish hemocyte lysate
-
Soderhall, K. 1983. Beta-1,3-glucan enhancement of protease activity in crayfish hemocyte lysate. Comp. Biochem. Physiol. B 74:221-224.
-
(1983)
Comp. Biochem. Physiol. B
, vol.74
, pp. 221-224
-
-
Soderhall, K.1
-
33
-
-
0031776213
-
Cell wall preparations from environmental yeasts: Effect on alveolar macrophage function in vitro
-
Sorenson, W. G., Shahan, T. A., and Simpson, J. 1998. Cell wall preparations from environmental yeasts: Effect on alveolar macrophage function in vitro. Ann. Agric. Environ. Med. 5:65-71.
-
(1998)
Ann. Agric. Environ. Med
, vol.5
, pp. 65-71
-
-
Sorenson, W.G.1
Shahan, T.A.2
Simpson, J.3
-
34
-
-
1642536438
-
The role of signr1 and the beta-glucan receptor (dectin-1) in the nonopsonic recognition of yeast by specific macrophages
-
Taylor, P. R., Brown, G. D., Herre, J., Williams, D. L., Willment, J. A., and Gordon, S. 2004. The role of signr1 and the beta-glucan receptor (dectin-1) in the nonopsonic recognition of yeast by specific macrophages. J. Immunol. 172:1157-1162.
-
(2004)
J. Immunol
, vol.172
, pp. 1157-1162
-
-
Taylor, P.R.1
Brown, G.D.2
Herre, J.3
Williams, D.L.4
Willment, J.A.5
Gordon, S.6
-
35
-
-
0025038834
-
Discrimination betweenn endotoxin and (1->3)-beta-d-glucan using turbi-dimetric kinetic assay with limulus amebocyte lysate
-
Tsuchiya, M., Oishi, H., Takaoka, A., Fusamoto, M., and Matsuura, S. 1990. Discrimination betweenn endotoxin and (1->3)-beta-d-glucan using turbi-dimetric kinetic assay with limulus amebocyte lysate. Chem. Pharm. Bull. 38(9):2523-2526.
-
(1990)
Chem. Pharm. Bull
, vol.38
, Issue.9
, pp. 2523-2526
-
-
Tsuchiya, M.1
Oishi, H.2
Takaoka, A.3
Fusamoto, M.4
Matsuura, S.5
-
36
-
-
0141918816
-
The role of mannose-binding lectin in health and disease
-
Turner, M. W. 2003. The role of mannose-binding lectin in health and disease. Mol. Immunol. 40:423-429.
-
(2003)
Mol. Immunol
, vol.40
, pp. 423-429
-
-
Turner, M.W.1
-
37
-
-
0029977686
-
Glucan-based macrophage stimulators - A review of their anti-infective potential
-
Williams, D. L., Mueller, A., and Browder, W. 1996. Glucan-based macrophage stimulators - A review of their anti-infective potential. Clin. Immunother. 5:392-399.
-
(1996)
Clin. Immunother
, vol.5
, pp. 392-399
-
-
Williams, D.L.1
Mueller, A.2
Browder, W.3
-
38
-
-
0345552244
-
The beta-glucan-binding lectin site of mouse cr3 (cd11b/cd18) and its function in generating a primed state of the receptor that mediates cytotoxic activation in response to ic3b-opsonized target cells
-
Xia, Y., Vetvicka, V., Yan, J., Hanikyrova, M., Mayadas, T., and Ross, G. D. 1999. The beta-glucan-binding lectin site of mouse cr3 (cd11b/cd18) and its function in generating a primed state of the receptor that mediates cytotoxic activation in response to ic3b-opsonized target cells. J. Immunol. 162:2281-2290.
-
(1999)
J. Immunol
, vol.162
, pp. 2281-2290
-
-
Xia, Y.1
Vetvicka, V.2
Yan, J.3
Hanikyrova, M.4
Mayadas, T.5
Ross, G.D.6
-
39
-
-
33746829125
-
Animal model of (1->3)-beta-glucan-induced pulmonary inflammation in rats
-
eds. S.-H. Young and V. Castranova, pp, New York: Taylor & Francis
-
Young, S.-H., and Castranova, V. 2005. Animal model of (1->3)-beta-glucan-induced pulmonary inflammation in rats. In Toxicology of 1->3-beta-glucans, Glucans as a marker for fungal exposure, eds. S.-H. Young and V. Castranova, pp. 65-93. New York: Taylor & Francis.
-
(2005)
Toxicology of 1->3-beta-glucans, Glucans as a marker for fungal exposure
, pp. 65-93
-
-
Young, S.-H.1
Castranova, V.2
-
40
-
-
0035955456
-
Acute inflammation and recovery in rats after intratracheal instillation of a 1-> 3 -beta-glucan (zymosan a)
-
Young, S.-H., Robinson, V. A., Barger, M., Porter, D. W., Frazer, D. G., and Castranova, V. 2001a. Acute inflammation and recovery in rats after intratracheal instillation of a 1-> 3 -beta-glucan (zymosan a). J. Toxicol. Environ. Health A 64:311-325.
-
(2001)
J. Toxicol. Environ. Health A
, vol.64
, pp. 311-325
-
-
Young, S.-H.1
Robinson, V.A.2
Barger, M.3
Porter, D.W.4
Frazer, D.G.5
Castranova, V.6
-
41
-
-
0035827579
-
Molecular mechanism of TNF-a production in 1->3-b-glucan (zymosan) activated macrophages
-
Young, S.-H., Ye, J., Frazer, D. G., Shi, X., and Castranova, V. 2001b. Molecular mechanism of TNF-a production in 1->3-b-glucan (zymosan) activated macrophages. J. Biol. Chem. 276:20781-20787.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 20781-20787
-
-
Young, S.-H.1
Ye, J.2
Frazer, D.G.3
Shi, X.4
Castranova, V.5
-
42
-
-
0036473558
-
Modified endotoxin responses in rats pre-treated with 1->3-beta -glucan (zymosan a)
-
Young, S.-H., Robinson, V. A., Barger, M., Zeidler, P., Porter, D. W., Frazer, D. G., and Castranova, V. 2002. Modified endotoxin responses in rats pre-treated with 1->3-beta -glucan (zymosan a). Toxicol. Appl. Pharmacol. 178:172-179.
-
(2002)
Toxicol. Appl. Pharmacol
, vol.178
, pp. 172-179
-
-
Young, S.-H.1
Robinson, V.A.2
Barger, M.3
Zeidler, P.4
Porter, D.W.5
Frazer, D.G.6
Castranova, V.7
-
43
-
-
0037470980
-
Partially opened triple helix is the biologically active conformation of 1 - >3-beta-glucans that induces pulmonary inflammation in rats
-
Young, S.-H., Robinson, V. A., Barger, M., Frazer, D. G., Castranova, V., and Jacobs, R. R. 2003a. Partially opened triple helix is the biologically active conformation of 1 - >3-beta-glucans that induces pulmonary inflammation in rats. J. Toxicol. Environ. Health A 66:551-563.
-
(2003)
J. Toxicol. Environ. Health A
, vol.66
, pp. 551-563
-
-
Young, S.-H.1
Robinson, V.A.2
Barger, M.3
Frazer, D.G.4
Castranova, V.5
Jacobs, R.R.6
-
44
-
-
0037427936
-
Exposure to particulate 1 - >3-beta-glucans induces greater pulmonary toxicity than soluble 1 - >3-betaglucans in rats
-
Young, S.-H., Robinson, V. A., Barger, M., Whitmer, M., Porter, D. W., Frazer, D. G., and Castranova, V. 2003b. Exposure to particulate 1 - >3-beta-glucans induces greater pulmonary toxicity than soluble 1 - >3-betaglucans in rats. J. Toxicol. Environ. Health A 66:25-38.
-
(2003)
J. Toxicol. Environ. Health A
, vol.66
, pp. 25-38
-
-
Young, S.-H.1
Robinson, V.A.2
Barger, M.3
Whitmer, M.4
Porter, D.W.5
Frazer, D.G.6
Castranova, V.7
-
45
-
-
0028340546
-
Differential blocking of coagulation-activating pathways of limulus amebocyte lysate
-
Zhang, G. H., Baek, L., Buchardt, O., and Koch, C. 1994. Differential blocking of coagulation-activating pathways of limulus amebocyte lysate. J. Clin. Microbiol. 32:1537-1541.
-
(1994)
J. Clin. Microbiol
, vol.32
, pp. 1537-1541
-
-
Zhang, G.H.1
Baek, L.2
Buchardt, O.3
Koch, C.4
|