메뉴 건너뛰기




Volumn 27, Issue 11, 2013, Pages 4476-4488

A de novo-designed antimicrobial peptide with activity against multiresistant Staphylococcus aureus acting on RsbW kinase

Author keywords

B Transcription factor; DNA binding; NanoSIMS

Indexed keywords

AMINO ACID; PHOSPHOTRANSFERASE; POLYPEPTIDE ANTIBIOTIC AGENT; RSBW KINASE; SP1 1; UNCLASSIFIED DRUG;

EID: 84887113318     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.13-234575     Document Type: Article
Times cited : (21)

References (72)
  • 1
    • 14544282377 scopus 로고    scopus 로고
    • Antimicrobial peptides: Pore formers or metabolic inhibitors in bacteria?
    • DOI 10.1038/nrmicro1098
    • Brogden, K. A. (2005) Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? Nat. Rev. Microbiol. 3, 238-250 (Pubitemid 40298223)
    • (2005) Nature Reviews Microbiology , vol.3 , Issue.3 , pp. 238-250
    • Brogden, K.A.1
  • 2
    • 79960931688 scopus 로고    scopus 로고
    • Host-defense peptides: From biology to therapeutic strategies
    • Mangoni, M. L. (2011) Host-defense peptides: from biology to therapeutic strategies. Cell. Mol. Life Sci. 68, 2157-2159
    • (2011) Cell. Mol. Life Sci. , vol.68 , pp. 2157-2159
    • Mangoni, M.L.1
  • 3
    • 84863855517 scopus 로고    scopus 로고
    • Cationic antimicrobial peptides in clinical development, with special focus on thanatin and heliomicin
    • Andres, E. (2012) Cationic antimicrobial peptides in clinical development, with special focus on thanatin and heliomicin. Eur. J. Clin. Microbiol. Infect. Dis. 31, 881-888
    • (2012) Eur. J. Clin. Microbiol. Infect. Dis. , vol.31 , pp. 881-888
    • Andres, E.1
  • 4
    • 80055054079 scopus 로고    scopus 로고
    • The potential of antimicrobial peptides as biocides
    • Laverty, G., and Gorman., S. P., and Gilmore, B. F. (2011) The potential of antimicrobial peptides as biocides. Int. J. Mol. Sci. 12, 6566-6596
    • (2011) Int. J. Mol. Sci. , vol.12 , pp. 6566-6596
    • Laverty, G.1    Gorman, S.P.2    Gilmore, B.F.3
  • 5
    • 80051785173 scopus 로고    scopus 로고
    • The expanding scope of antimicrobial peptide structures and their modes of action
    • Nguyen, L. T., and Haney., E. F., and Vogel, H. J. (2011) The expanding scope of antimicrobial peptide structures and their modes of action. Trends Biotechnol. 29, 464-472
    • (2011) Trends Biotechnol. , vol.29 , pp. 464-472
    • Nguyen, L.T.1    Haney, E.F.2    Vogel, H.J.3
  • 6
    • 0019386682 scopus 로고
    • Sequence and specificity of two antibacterial proteins involved in insect immunity
    • DOI 10.1038/292246a0
    • Steiner, H., Hultmark, D., Engstrom, A., Bennich, H., and Boman, H. G. (1981) Sequence and specificity of two antibacterial proteins involved in insect immunity. Nature 292, 246-248 (Pubitemid 11001840)
    • (1981) Nature , vol.292 , Issue.5820 , pp. 246-248
    • Steiner, H.1    Hultmark, D.2    Engstrom, A.3
  • 7
    • 2042513493 scopus 로고
    • Magainins, a class of antimicrobial peptides from Xenopus skin: Isolation, characterization of two active forms, and partial cDNA sequence of a precursor
    • Zasloff, M. (1987) Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor. Proc. Natl. Acad. Sci. U. S. A. 84, 5449-5453 (Pubitemid 17129018)
    • (1987) Proceedings of the National Academy of Sciences of the United States of America , vol.84 , Issue.15 , pp. 5449-5453
    • Zasloff, M.1
  • 8
    • 1642545489 scopus 로고    scopus 로고
    • Anti-microbial peptides: From invertebrates to vertebrates
    • DOI 10.1111/j.0105-2896.2004.0124.x
    • Bulet, P., Stocklin, R., and Menin, L. (2004) Anti-microbial peptides: from invertebrates to vertebrates. Immunol. Rev. 198, 169-184 (Pubitemid 38406943)
    • (2004) Immunological Reviews , vol.198 , pp. 169-184
    • Bulet, P.1    Stocklin, R.2    Menin, L.3
  • 10
    • 33745217570 scopus 로고    scopus 로고
    • The co-evolution of host cationic antimicrobial peptides and microbial resistance
    • DOI 10.1038/nrmicro1441, PII N1441
    • Peschel, A., and Sahl, H. G. (2006) The co-evolution of host cationic antimicrobial peptides and microbial resistance. Nat. Rev. Microbiol. 4, 529-536 (Pubitemid 43905612)
    • (2006) Nature Reviews Microbiology , vol.4 , Issue.7 , pp. 529-536
    • Peschel, A.1    Sahl, H.-G.2
  • 11
    • 33947393032 scopus 로고    scopus 로고
    • Antimicrobial peptides: An overview of a promising class of therapeutics
    • DOI 10.2478/s11535-007-0010-5
    • Giuliani, A., Pirri, G., and Nicoletto, S. F. (2007) Antimicrobial peptides: an overview of a promising class of therapeutics. Central Eur. J. Biol. 2, 1-33 (Pubitemid 46450753)
    • (2007) Central European Journal of Biology , vol.2 , Issue.1 , pp. 1-33
    • Giuliani, A.1    Pirri, G.2    Nicoletto, S.F.3
  • 12
    • 0032489294 scopus 로고    scopus 로고
    • Mechanism of action of the antimicrobial peptide buforin II: Buforin II kills microorganisms by penetrating the cell membrane and inhibiting cellular functions
    • DOI 10.1006/bbrc.1998.8159
    • Park, C. B., and Kim., H. S., and Kim, S. C. (1998) Mechanism of action of the antimicrobial peptide buforin II: buforin II kills microorganisms by penetrating the cell membrane and inhibiting cellular functions. Biochem. Biophys. Res. Commun. 244, 253-257 (Pubitemid 28419934)
    • (1998) Biochemical and Biophysical Research Communications , vol.244 , Issue.1 , pp. 253-257
    • Park, C.B.1    Kim, H.S.2    Kim, S.C.3
  • 13
    • 0036168570 scopus 로고    scopus 로고
    • Sublethal concentrations of pleurocidin-derived antimicrobial peptides inhibit macromolecular synthesis in Escherichia coli
    • DOI 10.1128/AAC.46.3.605-614.2002
    • Patrzykat, A., and Friedrich., C. L., Zhang, L., Mendoza, V., and Hancock, R. E. (2002) Sublethal concentrations of pleurocidin-derived antimicrobial peptides inhibit macromolecular synthesis in Escherichia coli. Antimicrob. Agents Chemother. 46, 605-614 (Pubitemid 34162506)
    • (2002) Antimicrobial Agents and Chemotherapy , vol.46 , Issue.3 , pp. 605-614
    • Patrzykat, A.1    Friedrich, C.L.2    Zhang, L.3    Mendoza, V.4    Hancock, R.E.W.5
  • 14
    • 0035853022 scopus 로고    scopus 로고
    • The antibacterial peptide pyrrhocoricin inhibits the ATPase actions of DnaK and prevents chaperone-assisted protein folding
    • DOI 10.1021/bi002656a
    • Kragol, G., Lovas, S., Varadi, G., Condie, B. A., Hoffmann, R., and Otvos, L., Jr. (2001) The antibacterial peptide pyrrhocoricin inhibits the ATPase actions of DnaK and prevents chaper-one-assisted protein folding. Biochemistry 40, 3016-3026 (Pubitemid 32206189)
    • (2001) Biochemistry , vol.40 , Issue.10 , pp. 3016-3026
    • Kragol, G.1    Lovas, S.2    Varadi, G.3    Condie, B.A.4    Hoffmann, R.5    Otvos Jr., L.6
  • 15
    • 0034332193 scopus 로고    scopus 로고
    • The human antimicrobial and chemotactic peptides LL-37 and alpha-defensins are expressed by specific lymphocyte and monocyte populations
    • Agerberth, B., Charo, J., Werr, J., Olsson, B., Idali, F., Lindbom, L., Kiessling, R., Jornvall, H., Wigzell, H., and Gudmundsson, G. H. (2000) The human antimicrobial and chemotactic peptides LL-37 and alpha-defensins are expressed by specific lymphocyte and monocyte populations. Blood 96, 3086-3093
    • (2000) Blood , vol.96 , pp. 3086-3093
    • Agerberth, B.1    Charo, J.2    Werr, J.3    Olsson, B.4    Idali, F.5    Lindbom, L.6    Kiessling, R.7    Jornvall, H.8    Wigzell, H.9    Gudmundsson, G.H.10
  • 17
    • 16644364407 scopus 로고    scopus 로고
    • The need for new antibiotics
    • Livermore, D. M. (2004) The need for new antibiotics. Clin. Microbiol. Infect. 10(Suppl. 4), 1-9
    • (2004) Clin. Microbiol. Infect. , vol.10 , Issue.SUPPL. 4 , pp. 1-9
    • Livermore, D.M.1
  • 18
    • 78650534390 scopus 로고    scopus 로고
    • Multiresistant bacteria and current therapy: The economical side of the story
    • Wilke, M. H. (2010) Multiresistant bacteria and current therapy: the economical side of the story. Eur. J. Med. Res. 15, 571-576
    • (2010) Eur. J. Med. Res. , vol.15 , pp. 571-576
    • Wilke, M.H.1
  • 19
    • 73649107896 scopus 로고    scopus 로고
    • Staphylococcus aureus host cell invasion and post-invasion events
    • Sinha, B., and Fraunholz, M. (2010) Staphylococcus aureus host cell invasion and post-invasion events. Int. J. Med. Microbiol. 300, 170-175
    • (2010) Int. J. Med. Microbiol. , vol.300 , pp. 170-175
    • Sinha, B.1    Fraunholz, M.2
  • 20
    • 69249083586 scopus 로고    scopus 로고
    • Waves of resistance: Staphylococcus aureus in the antibiotic era
    • Chambers, H. F., and Deleo, F. R. (2009) Waves of resistance: Staphylococcus aureus in the antibiotic era. Nat. Rev. Microbiol. 7, 629-641
    • (2009) Nat. Rev. Microbiol. , vol.7 , pp. 629-641
    • Chambers, H.F.1    Deleo, F.R.2
  • 21
    • 39449086721 scopus 로고    scopus 로고
    • Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances
    • DOI 10.1038/nprot.2007.521, PII NPROT.2007.521
    • Wiegand, I., Hilpert, K., and Hancock, R. E. (2008) Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances. Nat. Protoc. 3, 163-175 (Pubitemid 351266501)
    • (2008) Nature Protocols , vol.3 , Issue.2 , pp. 163-175
    • Wiegand, I.1    Hilpert, K.2    Hancock, R.E.W.3
  • 22
    • 70349737935 scopus 로고    scopus 로고
    • Transcriptome analysis of the responses of staphylococcus aureus to antimicrobial peptides and characterization of the roles of vraDE and vraSR in antimicrobial resistance
    • Pietiainen, M., Francois, P., Hyyrylainen, H. L., Tangomo, M., Sass, V., Sahl, H. G., Schrenzel, J., and Kontinen, V. P. (2009) Transcriptome analysis of the responses of Staphylococcus aureus to antimicrobial peptides and characterization of the roles of vraDE and vraSR in antimicrobial resistance. BMC Genomics 10, 429
    • (2009) BMC Genomics , vol.10 , pp. 429
    • Pietiainen, M.1    Francois, P.2    Hyyrylainen, H.L.3    Tangomo, M.4    Sass, V.5    Sahl, H.G.6    Schrenzel, J.7    Kontinen, V.P.8
  • 23
    • 25444518699 scopus 로고    scopus 로고
    • A generic approach for the design of whole-genome oligoarrays, validated for genomotyping, deletion mapping and gene expression analysis on staphylococcus aureus
    • Charbonnier, Y., Gettler, B., Francois, P., Bento, M., Renzoni, A., Vaudaux, P., Schlegel, W., and Schrenzel, J. (2005) A generic approach for the design of whole-genome oligoarrays, validated for genomotyping, deletion mapping and gene expression analysis on Staphylococcus aureus. BMC Genomics 6, 95
    • (2005) BMC Genomics , vol.6 , pp. 95
    • Charbonnier, Y.1    Gettler, B.2    Francois, P.3    Bento, M.4    Renzoni, A.5    Vaudaux, P.6    Schlegel, W.7    Schrenzel, J.8
  • 28
  • 30
    • 37549035397 scopus 로고    scopus 로고
    • Genome sequence of staphylococcus aureus strain newman and comparative analysis of staphylococcal genomes: Polymorphism and evolution of two major pathogenicity Islands
    • Baba, T., Bae, T., Schneewind, O., Takeuchi, F., and Hiramatsu, K. (2008) Genome sequence of Staphylococcus aureus strain Newman and comparative analysis of staphylococcal genomes: polymorphism and evolution of two major pathogenicity islands. J. Bacteriol. 190, 300-310
    • (2008) J. Bacteriol. , vol.190 , pp. 300-310
    • Baba, T.1    Bae, T.2    Schneewind, O.3    Takeuchi, F.4    Hiramatsu, K.5
  • 33
    • 0033732564 scopus 로고    scopus 로고
    • GATEWAY recombinational cloning: Application to the cloning of large numbers of open reading frames or ORFeomes
    • Walhout, A. J., and Temple., G. F., Brasch, M. A., Hartley, J. L., and Lorson., M. A., van den Heuvel, S., and Vidal, M. (2000) GATEWAY recombinational cloning: application to the cloning of large numbers of open reading frames or ORFeomes. Methods Enzymol. 328, 575-592
    • (2000) Methods Enzymol. , vol.328 , pp. 575-592
    • Walhout, A.J.1    Temple, G.F.2    Brasch, M.A.3    Hartley, J.L.4    Lorson, M.A.5    Van Den Heuvel, S.6    Vidal, M.7
  • 34
    • 0033676098 scopus 로고    scopus 로고
    • DNA cloning using in vitro site-specific recombination
    • Hartley, J. L., and Temple., G. F., and Brasch, M. A. (2000) DNA cloning using in vitro site-specific recombination. Genome Res. 10, 1788-1795
    • (2000) Genome Res. , vol.10 , pp. 1788-1795
    • Hartley, J.L.1    Temple, G.F.2    Brasch, M.A.3
  • 35
    • 54349114887 scopus 로고    scopus 로고
    • Construction of a reading frame-independent yeast two-hybrid vector system for site-specific recombinational cloning and protein interaction screening
    • Maier, R., Brandner, C, Hintner, H., Bauer, J., and Onder, K (2008) Construction of a reading frame-independent yeast two-hybrid vector system for site-specific recombinational cloning and protein interaction screening. BioTechniques 45, 235-244
    • (2008) BioTechniques , vol.45 , pp. 235-244
    • Maier, R.1    Brandner, C.2    Hintner, H.3    Bauer, J.4    Onder, K.5
  • 36
    • 65249120167 scopus 로고    scopus 로고
    • Role of RsbU in controlling SigB activity in staphylococcus aureus following alkaline stress
    • Pane-Farre, J., Jonas, B., and Hardwick., S. W., Gronau, K., Lewis, R J., Hecker, M., and Engelmann, S. (2009) Role of RsbU in controlling SigB activity in Staphylococcus aureus following alkaline stress. J. Bacteriol. 191, 2561-2573
    • (2009) J. Bacteriol. , vol.191 , pp. 2561-2573
    • Pane-Farre, J.1    Jonas, B.2    Hardwick, S.W.3    Gronau, K.4    Lewis, R.J.5    Hecker, M.6    Engelmann, S.7
  • 37
    • 77952700194 scopus 로고    scopus 로고
    • Repair of global regulators in staphylococcus aureus 8325 and comparative analysis with other clinical isolates
    • Herbert, S., and Ziebandt., A. K., Ohlsen, K., Schafer, T., Hecker, M., Albrecht, D., Novick, R., and Gotz, F. (2010) Repair of global regulators in Staphylococcus aureus 8325 and comparative analysis with other clinical isolates. Infect. Immun. 78, 2877-2889
    • (2010) Infect. Immun. , vol.78 , pp. 2877-2889
    • Herbert, S.1    Ziebandt, A.K.2    Ohlsen, K.3    Schafer, T.4    Hecker, M.5    Albrecht, D.6    Novick, R.7    Gotz, F.8
  • 39
    • 23144451932 scopus 로고    scopus 로고
    • Progress in analytical imaging of the cell by dynamic secondary ion mass spectrometry (SIMS microscopy)
    • DOI 10.1016/j.bbagen.2005.05.013, PII S0304416505001546, Some Insights into the Biophysics of Complex Systems
    • Guerquin-Kern, J. L., Wu, T. D., Quintana, C, and Croisy, A (2005) Progress in analytical imaging of the cell by dynamic secondary ion mass spectrometry (SIMS microscopy). Biochim. Biophys. Acta 1724, 228-238 (Pubitemid 41080032)
    • (2005) Biochimica et Biophysica Acta - General Subjects , vol.1724 , Issue.3 , pp. 228-238
    • Guerquin-Kern, J.-L.1    Wu, T.-D.2    Quintana, C.3    Croisy, A.4
  • 40
    • 84887034427 scopus 로고    scopus 로고
    • Cameca SAS, Genevilliers, France
    • Cameca (2009) NanoSIMS 50/50L instrumentation [16 pp. booklet], Cameca SAS, Genevilliers, France; http://www.cameca.com/literature/product-brochures. aspx
    • (2009) NanoSIMS 50/50L Instrumentation [16 Pp. Booklet]
  • 41
    • 84856716159 scopus 로고    scopus 로고
    • Detecting metabolic activities in single cells, with emphasis on nanoSIMS
    • Musat, N., Foster, R., Vagner, T., Adam, B., and Kuypers, M. M. (2012) Detecting metabolic activities in single cells, with emphasis on nanoSIMS. FEMS Microbiol. Rev. 36, 486-511
    • (2012) FEMS Microbiol. Rev. , vol.36 , pp. 486-511
    • Musat, N.1    Foster, R.2    Vagner, T.3    Adam, B.4    Kuypers, M.M.5
  • 42
    • 78751575968 scopus 로고    scopus 로고
    • C-terminal amidation of PMAP-23: Translocation to the inner membrane of gram-negative bacteria
    • Kim, J. Y., and Park., S. C., Yoon, M. Y., Hahm, K. S., and Park, Y. (2011) C-terminal amidation of PMAP-23: translocation to the inner membrane of Gram-negative bacteria. Amino Acids 40, 183-195
    • (2011) Amino Acids , vol.40 , pp. 183-195
    • Kim, J.Y.1    Park, S.C.2    Yoon, M.Y.3    Hahm, K.S.4    Park, Y.5
  • 43
    • 84855778047 scopus 로고    scopus 로고
    • Characterization of BmKbpp, a multifunctional peptide from the chinese scorpion mesobuthus martensii karsch: Gaining insight into a new mechanism for the functional diversification of scorpion venom peptides
    • Zeng, X. C., Wang, S., Nie, Y., Zhang, L., and Luo, X. (2012) Characterization of BmKbpp, a multifunctional peptide from the Chinese scorpion Mesobuthus martensii Karsch: gaining insight into a new mechanism for the functional diversification of scorpion venom peptides. Peptides 33, 44-51
    • (2012) Peptides , vol.33 , pp. 44-51
    • Zeng, X.C.1    Wang, S.2    Nie, Y.3    Zhang, L.4    Luo, X.5
  • 44
    • 84862968750 scopus 로고    scopus 로고
    • Decoding the functional roles of cationic side chains of the major antimicrobial region of human cathelicidin LL-37
    • Wang, G., and Epand., R. F., Mishra, B., Lushnikova, T., Thomas, V. C., and Bayles., K. W., and Epand, R. M. (2012) Decoding the functional roles of cationic side chains of the major antimicrobial region of human cathelicidin LL-37. Antimicrob. Agents Chemother. 56, 845-856
    • (2012) Antimicrob. Agents Chemother. , vol.56 , pp. 845-856
    • Wang, G.1    Epand, R.F.2    Mishra, B.3    Lushnikova, T.4    Thomas, V.C.5    Bayles, K.W.6    Epand, R.M.7
  • 45
    • 78651068827 scopus 로고    scopus 로고
    • Recombinant antimicrobial peptide hPAB-beta expressed in pichia pastoris, a potential agent active against methicillin-resistant staphylococcus aureus
    • Chen, Z., Wang, D., Cong, Y., Wang, J., Zhu, J., Yang, J., Hu, Z., Hu, X., Tan, Y., Hu, F., and Rao, X. (2011) Recombinant antimicrobial peptide hPAB-beta expressed in Pichia pastoris, a potential agent active against methicillin-resistant Staphylococcus aureus. Appl. Microbiol. Biotechnol. 89, 281-291
    • (2011) Appl. Microbiol. Biotechnol. , vol.89 , pp. 281-291
    • Chen, Z.1    Wang, D.2    Cong, Y.3    Wang, J.4    Zhu, J.5    Yang, J.6    Hu, Z.7    Hu, X.8    Tan, Y.9    Hu, F.10    Rao, X.11
  • 46
    • 0037371597 scopus 로고    scopus 로고
    • Mechanisms of antimicrobial peptide action and resistance
    • DOI 10.1124/pr.55.1.2
    • Yeaman, M. R., and Yount, N. Y. (2003) Mechanisms of antimicrobial peptide action and resistance. Pharmacol. Rev. 55, 27-55 (Pubitemid 36268398)
    • (2003) Pharmacological Reviews , vol.55 , Issue.1 , pp. 27-55
    • Yeaman, M.R.1    Yount, N.Y.2
  • 47
    • 9144258550 scopus 로고    scopus 로고
    • Antibacterial proline-rich oligopeptides and their target proteins
    • Markossian, K. A., and Zamyatnin., A. A., and Kurganov, B. I. (2004) Antibacterial proline-rich oligopeptides and their target proteins. Biochemistry (Mosc.) 69, 1082-1091
    • (2004) Biochemistry (Mosc.) , vol.69 , pp. 1082-1091
    • Markossian, K.A.1    Zamyatnin, A.A.2    Kurganov, B.I.3
  • 48
    • 0027318984 scopus 로고
    • Selective inhibition of microbial serine proteases by eNAP-2, an antimicrobial peptide from equine neutrophils
    • Couto, M. A., and Harwig., S. S., and Lehrer, R. I. (1993) Selective inhibition of microbial serine proteases by eNAP-2, an antimicrobial peptide from equine neutrophils. Infect. Immun. 61, 2991-2994 (Pubitemid 23182298)
    • (1993) Infection and Immunity , vol.61 , Issue.7 , pp. 2991-2994
    • Couto, M.A.1    Harwig, S.S.L.2    Lehrer, R.I.3
  • 49
    • 78651257345 scopus 로고    scopus 로고
    • Structural characterization of the multidomain regulatory protein rv1364c from mycobacterium tuberculosis
    • King-Scott, J., Konarev, P. V., Panjikar, S., Jordanova, R., Svergun, D. I., and Tucker, P. A. (2011) Structural characterization of the multidomain regulatory protein Rv1364c from Mycobacterium tuberculosis. Structure 19, 56-69
    • (2011) Structure , vol.19 , pp. 56-69
    • King-Scott, J.1    Konarev, P.V.2    Panjikar, S.3    Jordanova, R.4    Svergun, D.I.5    Tucker, P.A.6
  • 50
    • 35848954992 scopus 로고    scopus 로고
    • SigB-dependent general stress response in Bacillus subtilis and related gram-positive bacteria
    • DOI 10.1146/annurev.micro.61.080706.093445
    • Hecker, M., Pane-Farre, J., and Volker, U. (2007) SigB-dependent general stress response in Bacillus subtilis and related gram-positive bacteria. Annu. Rev. Microbiol. 61, 215-236 (Pubitemid 350058207)
    • (2007) Annual Review of Microbiology , vol.61 , pp. 215-236
    • Hecker, M.1    Pane-Farre, J.2    Volker, U.3
  • 52
    • 0032951950 scopus 로고    scopus 로고
    • The Staphylococcus aureus rsbW (orf159) gene encodes an anti-sigma factor of SigB
    • Miyazaki, E., and Chen., J. M., Ko, C., and Bishai, W. R. (1999) The Staphylococcus aureus rsbW (orf159) gene encodes an anti-sigma factor of SigB. J. Bacteriol. 181, 2846-2851 (Pubitemid 29211102)
    • (1999) Journal of Bacteriology , vol.181 , Issue.9 , pp. 2846-2851
    • Miyazaki, E.1    Chen, J.-M.2    Ko, C.3    Bishai, W.R.4
  • 53
    • 0031659829 scopus 로고    scopus 로고
    • Deletion of the alternative sigma factor σ(B) in Staphylococcus aureus reveals its function as a global regulator of virulence genes
    • Kullik, I., Giachino, P., and Fuchs, T. (1998) Deletion of the alternative sigma factor sigmaB in Staphylococcus aureus reveals its function as a global regulator of virulence genes. J. Bacteriol. 180, 4814-4820 (Pubitemid 28429367)
    • (1998) Journal of Bacteriology , vol.180 , Issue.18 , pp. 4814-4820
    • Kullik, I.1    Giachino, P.2    Fuchs, T.3
  • 57
    • 84868002629 scopus 로고    scopus 로고
    • Linking environmental processes to the in situ functioning of microorganisms by high-resolution secondary ion mass spectrometry (Nano-SIMS) and scanning transmission X-ray microscopy (STXM)
    • Behrens, S., Kappler, A., and Obst, M. (2012) Linking environmental processes to the in situ functioning of microorganisms by high-resolution secondary ion mass spectrometry (Nano-SIMS) and scanning transmission X-ray microscopy (STXM). Environ. Microbiol. 14, 2851-2869
    • (2012) Environ. Microbiol. , vol.14 , pp. 2851-2869
    • Behrens, S.1    Kappler, A.2    Obst, M.3
  • 59
    • 67349215276 scopus 로고    scopus 로고
    • Physiological proteomics and stress/starvation responses in bacillus subtilis and staphylococcus aureus
    • Hecker, M., Reder, A., Fuchs, S., Pagels, M., and Engelmann, S. (2009) Physiological proteomics and stress/starvation responses in Bacillus subtilis and Staphylococcus aureus. Res. Microbiol. 160, 245-258
    • (2009) Res. Microbiol. , vol.160 , pp. 245-258
    • Hecker, M.1    Reder, A.2    Fuchs, S.3    Pagels, M.4    Engelmann, S.5
  • 60
    • 80052396610 scopus 로고    scopus 로고
    • Vancomycin activates sigma in vancomycin-resistant staphylococcus aureus resulting in the enhancement of cytotoxicity
    • Chen, H. Y., and Chen., C. C., Fang, C. S., Hsieh, Y. T., and Lin., M. H., and Shu, J. C. (2011) Vancomycin activates sigma in vancomycin-resistant Staphylococcus aureus resulting in the enhancement of cytotoxicity. PLoS ONE 6, e24472
    • (2011) PLoS ONE , vol.6
    • Chen, H.Y.1    Chen, C.C.2    Fang, C.S.3    Hsieh, Y.T.4    Lin, M.H.5    Shu, J.C.6
  • 61
    • 66849140962 scopus 로고    scopus 로고
    • Role of the alternative sigma factor sigma on staphylococcus aureus resistance to stresses of relevance to food preservation
    • Cebrian, G., Sagarzazu, N., Aertsen, A., Pagan, R., Condon, S., and Manas, P. (2009) Role of the alternative sigma factor sigma on Staphylococcus aureus resistance to stresses of relevance to food preservation. J. Appl. Microbiol. 107, 187-196
    • (2009) J. Appl. Microbiol. , vol.107 , pp. 187-196
    • Cebrian, G.1    Sagarzazu, N.2    Aertsen, A.3    Pagan, R.4    Condon, S.5    Manas, P.6
  • 63
    • 77949473313 scopus 로고    scopus 로고
    • Production of icaADBC-encoded polysaccharide intercellular adhesin and therapeutic failure in pediatric patients with staphylococcal device-related infections
    • Diemond-Hernandez, B., Solorzano-Santos, F., Leanos-Miranda, B., Peregrino-Bejarano, L., and Miranda-Novales, G. (2010) Production of icaADBC-encoded polysaccharide intercellular adhesin and therapeutic failure in pediatric patients with Staphylococcal device-related infections. BMC Infect. Dis. 10, 68
    • (2010) BMC Infect. Dis. , vol.10 , pp. 68
    • Diemond-Hernandez, B.1    Solorzano-Santos, F.2    Leanos-Miranda, B.3    Peregrino-Bejarano, L.4    Miranda-Novales, G.5
  • 64
    • 3042546274 scopus 로고    scopus 로고
    • B by repression of the negative regulator gene icaR
    • DOI 10.1128/IAI.72.7.3838-3848.2004
    • Knobloch, J. K., Jager, S., Horstkotte, M. A., Rohde, H., and Mack, D. (2004) RsbU-dependent regulation of Staphylococcus epidermidis biofilm formation is mediated via the alternative sigma factor sigmaB by repression of the negative regulator gene icaR. Infect. Immun. 72, 3838-3848 (Pubitemid 38821896)
    • (2004) Infection and Immunity , vol.72 , Issue.7 , pp. 3838-3848
    • Knobloch, J.K.-M.1    Jager, S.2    Horstkotte, M.A.3    Rohde, H.4    Mack, D.5
  • 65
    • 63149097265 scopus 로고    scopus 로고
    • Interconnections between sigma B, agr, and proteolytic activity in staphylococcus aureus biofilm maturation
    • Lauderdale, K. J., and Boles., B. R., Cheung, A. L., and Horswill, A. R. (2009) Interconnections between Sigma B, agr, and proteolytic activity in Staphylococcus aureus biofilm maturation. Infect. Immun. 77, 1623-1635
    • (2009) Infect. Immun. , vol.77 , pp. 1623-1635
    • Lauderdale, K.J.1    Boles, B.R.2    Cheung, A.L.3    Horswill, A.R.4
  • 66
    • 0035100985 scopus 로고    scopus 로고
    • B activity depends on RsbU in Staphylococcus aureus
    • DOI 10.1128/JB.183.6.1843-1852.2001
    • Giachino, P., Engelmann, S., and Bischoff, M. (2001) Sigma(B) activity depends on RsbU in Staphylococcus aureus. J. Bacteriol. 183, 1843-1852 (Pubitemid 32225979)
    • (2001) Journal of Bacteriology , vol.183 , Issue.6 , pp. 1843-1852
    • Giachino, P.1    Engelmann, S.2    Bischoff, M.3
  • 67
    • 36549008206 scopus 로고    scopus 로고
    • New insights into the WalK/WalR (YycG/YycF) essential signal transduction pathway reveal a major role in controlling cell wall metabolism and biofilm formation in Staphylococcus aureus
    • DOI 10.1128/JB.00645-07
    • Dubrac, S., and Boneca., I. G., Poupel, O., and Msadek, T. (2007) New insights into the WalK/WalR (YycG/YycF) essential signal transduction pathway reveal a major role in controlling cell wall metabolism and biofilm formation in Staphylococcus aureus. J. Bacteriol. 189, 8257-8269 (Pubitemid 350178938)
    • (2007) Journal of Bacteriology , vol.189 , Issue.22 , pp. 8257-8269
    • Dubrac, S.1    Boneca, I.G.2    Poupel, O.3    Msadek, T.4
  • 69
    • 77949916499 scopus 로고    scopus 로고
    • Two-component signal transduction as potential drug targets in pathogenic bacteria
    • Gotoh, Y., Eguchi, Y., Watanabe, T., Okamoto, S., Doi, A., and Utsumi, R. (2010) Two-component signal transduction as potential drug targets in pathogenic bacteria. Curr. Opinion Microbiol. 13, 232-239
    • (2010) Curr. Opinion Microbiol. , vol.13 , pp. 232-239
    • Gotoh, Y.1    Eguchi, Y.2    Watanabe, T.3    Okamoto, S.4    Doi, A.5    Utsumi, R.6
  • 70
    • 0043122944 scopus 로고    scopus 로고
    • ExPASy: The proteomics server for in-depth protein knowledge and analysis
    • DOI 10.1093/nar/gkg563
    • Gasteiger, E., Gattiker, A., Hoogland, C., Ivanyi, I., and Appel., R. D., and Bairoch, A. (2003) ExPASy: The proteomics server for in-depth protein knowledge and analysis. Nucleic Acids Res. 31, 3784-3788 (Pubitemid 37442246)
    • (2003) Nucleic Acids Research , vol.31 , Issue.13 , pp. 3784-3788
    • Gasteiger, E.1    Gattiker, A.2    Hoogland, C.3    Ivanyi, I.4    Appel, R.D.5    Bairoch, A.6
  • 71
    • 0021152462 scopus 로고
    • Three-dimensional structure of membrane and surface proteins
    • Eisenberg, D. (1984) Three-dimensional structure of membrane and surface proteins. Annu. Rev. Biochem. 53, 595-623
    • (1984) Annu. Rev. Biochem. , vol.53 , pp. 595-623
    • Eisenberg, D.1
  • 72
    • 0025334980 scopus 로고
    • Improvements in protein secondary structure prediction by an enhanced neural network
    • DOI 10.1016/0022-2836(90)90154-E
    • Kneller, D. G., and Cohen., F. E., and Langridge, R. (1990) Improvements in protein secondary structure prediction by an enhanced neural network. J. Mol. Biol. 214, 171-182 (Pubitemid 20231217)
    • (1990) Journal of Molecular Biology , vol.214 , Issue.1 , pp. 171-182
    • Kneller, D.G.1    Cohen, F.E.2    Langridge, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.