The Staphylococcus aureus rsbW (orf159) gene encodes an anti-sigma factor of SigB

Journal of Bacteriology

Volumn 181, Issue 9, 1999, Pages 2846-2851

  Miyazaki, Eishi ^a   Chen, Jong Min ^a   Ko, Chiew ^a   Bishai, William R ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COAGULASE; HEAT SHOCK PROTEIN; HYBRID PROTEIN; SIGMA FACTOR; TRANSCRIPTION FACTOR; VIRULENCE FACTOR;

ARTICLE; BACILLUS SUBTILIS; BACTERIAL VIRULENCE; CROSS LINKING; GENETIC TRANSCRIPTION; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PURIFICATION; STAPHYLOCOCCUS AUREUS;

ANIMALIA; BACILLUS SUBTILIS; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; POSIBACTERIA; PROKARYOTA; STAPHYLOCOCCUS AUREUS;

EID: 0032951950     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.181.9.2846-2851.1999     Document Type: Article

References (41)

1. Alper, S., L. Duncan, and R. Losick. 1994. An adenosine nucleotide switch controlling the activity of a cell type-specific transcription factor in B. subtilis. Cell 77:195-205.
2. Bayer, M. G., J. H. Heinrichs, and A. L. Cheung. 1996. The molecular architecture of the sar locus in Staphylococcus aureus. J. Bacteriol. 178: 4563-4570.
3. B from Listeria monocytogenes and its role in osmotolerance. J. Bacteriol. 180:4547-4554.
4. B is regulated by a binding protein (RsbW) that blocks its association with core RNA polymerase. Proc. Natl. Acad. Sci. USA 90:2330-2334.
5. Brown, K. L., and K. T. Hughes. 1995. The role of anti-sigma factors in gene regulation. Mol. Microbiol. 16:397-404.
6. B controls the environmental stress response but not starvation survival or pathogenicity in a mouse abscess model. J. Bacteriol. 180:6082-6089.
7. Cheung, A. L., J. M. Koomey, C. A. Butler, S. J. Projan, and V. A. Fischetti. 1992. Regulation of exoprotein expression in Staphylococcus aureus by a locus (sar) distinct from agr. Proc. Natl. Acad. Sci. USA 89:6462-6466.
8. Cheung, A. L., and P. Ying. 1994. Regulation of α-and β-hemolysins by the sar locus of Staphylococcus aureus. J. Bacteriol. 176:580-585.
9. F and its antisigma factor SpoIIAB. Genes Dev. 10:2348-2358.
10. DeMaio, J., Y. Zhang, C. Ko, D. B. Young, and W. R. Bishai. 1996. A stationary-phase stress-response sigma factor from Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. USA 93:2790-2794.
11. DeMaio, J., Y. Zhang, C. Ko, and W. R. Bishai. 1997. The Mycobacterium tuberculosis sigF gene is part of a gene cluster with similarities to the Bacillus subtilis sigF and sigB operons. Tubercle Lung Dis. 78:3-12.
12. SB of Staphylococcus aureus: characterization and role in transcription of the global regulatory locus sar. J. Bacteriol. 179:6355-6359.
13. Deretic, V., M. J. Schurr, J. C. Boucher, and D. W. Martin. 1994. Conversion of Pseudomonas aeruginosa to mucoidy in cystic fibrosis: environmental stress and regulation of bacterial virulence by alternative sigma factors. J. Bacteriol. 176:2773-2780.
14. Dufour, A., and W. G. Haldenwang. 1994. Interactions between a Bacillus subtilis anti-σ factor (RsbW) and its antagonist (RsbV). J. Bacteriol. 176: 1813-1820.
15. Duncan, L., and R. Losick. 1993. SpoIIAB is an anti-sigma factor that binds to and inhibits transcription by regulatory protein sigma F from Bacillus subtilis. Proc. Natl. Acad. Sci. USA 15:2325-2329.
16. Emori, T. G., and R. P. Gayner. 1993. An overview of nosocomial infections, including the role of the microbiology laboratory. Clin. Microbiol. Rev. 6: 428-442.
17. Fang, F. C., S. J. Libby, N. A. Buchmeier, P. C. Loewen, J. Switala, J. Harwood, and D. G. Guiney. 1992. The alternative σ factor KatF (RpoS) regulates Salmonella virulence. Proc. Natl. Acad. Sci. USA 89:11978-11982.
18. Gillen, K. L., and K. T. Hughes. 1991. Molecular characterization of flgM, a gene encoding a negative regulator of flagellin synthesis in Salmonella typhimurium. J. Bacteriol. 173:6453-6459.
19. Hughes, K. T., and K. Mathee. 1998. The anti-sigma factors. Annu. Rev. Microbiol. 52:231-286.
20. Jonsson, P., M. Lindberg, I. Haraldsson, and T. Wadström. 1985. Virulence of Staphylococcus aureus in a mouse mastitis model: studies of alpha hemolysin, coagulase, and protein A as possible virulence determinants with protoplast fusion and gene cloning. Infect. Immun. 49:765-769.
21. Kaida, S., T. Miyata, Y. Yoshizawa, S. Kawabata, T. Morita, H. Igarashi, and S. Iwanaga. 1987. Nucleotide sequence of the staphylocoagulase gene: its unique COOH-terminal 8 tandem repeats. J. Biochem. 102:1177-1186.
22. Kullik, I., and P. Giachino. 1997. The alternative sigma factor sigma B in Staphylococcus aureus: regulation of the sigB operon in response to growth phase and heat shock. Arch. Microbiol. 167:151-159.
23. B in Staphylococcus aureus reveals its function as a global regulator of virulence genes. J. Bacteriol. 180:4814-4820.
24. Kuroda, M., T. Ohta, and H. Hayashi. 1995. Isolation and the gene cloning of an alkaline shock protein in methicillin-resistant Staphylococcus aureus. Biochem. Biophys. Res. Commun. 207:978-984.
25. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
26. Lowy, F. D. 1998. Staphylococcus aureus infections. N. Engl. J. Med. 339: 520-532.
27. Manna, A. C., M. G. Bayer, and A. L. Cheung. 1998. Transcriptional analysis of different promoters in the sar locus in Staphylococcus aureus. J. Bacteriol. 180:3828-3836.
28. Masuda, S. 1983. An efficient method foi the isolation of a mutant with an extremely low producibility of coagulase from a Staphylococcus aureus strain. Microbiol. Immunol. 27:801-805.
29. Mekalanos, J. J. 1992. Environmental signals controlling expression of virulence determinants in bacteria. J. Bacteriol. 174:1-7.
30. Michele, T. M., C. Ko, and W. R. Bishai. 1999. Exposure to antibiotics induces expression of the Mycobacterium tuberculosis sigF gene: implications for chemotherapy against mycobacterial persistors. Antimicrob. Agents Chemother. 43:218-225.
31. F, the first compartment-specific transcription factor of B. subtilis, is regulated by an anti-σ factor that is also a protein kinase. Cell 74:735-742.
32. Moreillon, P., J. M. Entenza, P. Francioli, D. McDevitt, T. J. Foster, P. Francois, and P. Vaudaux. 1995. Role of Staphylococcus aureus coagulase and clumping factor in pathogenesis of experimental endocarditis. Infect. Immun. 63:4738-4743.
33. Phonimdaeng, P., M. O'Reilly, P. Nowlan, A. J. Bramley, and T. J. Foster. 1990. The coagulase of Staphylococcus aureus 8325-4. Sequence analysis and virulence of site-specific coagulase-deficient mutants. Mol. Microbiol. 4: 393-404.
34. Sawai, T., K. Tomono, K. Yanagihara, Y. Yamamoto, M. Kaku, Y. Hirakata, H. Koga, T. Tashiro, and S. Kohno. 1997. Role of coagulase in a murine model of hematogenous pulmonary infection induced by intravenous injection of Staphylococcus aureus enmeshed in agar beads. Infect. Immun. 65: 466-471.
35. Seki, K., M. Ogasawara, J. Sakurada, M. Murai, and S. Masuda. 1989. Altered virulence of a pleiotropic Staphylococcus aureus mutant with low producibility of coagulase and other factors in mice. Microbiol. Immunol. 33: 981-990.
36. Sheagren, J. N. 1984. Staphylococcus aureus: the persistent pathogen. N. Engl. J. Med. 310:1368-1373.
37. Speller, D. C. E., A. P. Johnson, D. James, R. R. Marples, A. Charlett, and R. C. George. 1997. Resistance to methicillin and other antibiotics in isolates of Staphylococcus aureus from blood and cerebrospinal fluid, England and Wales, 1989-95. Lancet 350:323-325.
38. B and its role in acid tolerance and virulence of Listeria monocytogenes. J. Bacteriol. 180:3650-3656.
39. Wilkinson, B. J. 1997. Biology, p. 1-38. In K. B. Crossley and G. L. Archer (ed.), The staphylococci in human disease. Churchill Livingstone, New York, N.Y.
40. Wu, S., H. de Lencastre, and A. Tomasz. 1996. Sigma-B, a putative operon encoding alternate sigma factor of Staphylococcus aureus RNA polymerase: molecular cloning and DNA sequencing. J. Bacteriol. 178:6036-6042.
41. Yang, X., C. M. Kang, M. S. Brody, and C. W. Price. 1996. Opposing pairs of serine protein kinases and phosphatases transmit signals of environmental stress to activate a bacterial transcription factor. Genes Dev. 10:2265-2275.