A Drosophila model of closed head traumatic brain injury

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 44, 2013, Pages

  Katzenberger, Rebeccah J ^a   Loewen, Carin A ^b   Wassarman, Douglas R ^a   Petersen, Andrew J ^a   Ganetzky, Barry ^b   Wassarman, David A ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATAXIA; CONTROLLED STUDY; DEATH; DROSOPHILA MELANOGASTER; ENVIRONMENTAL FACTOR; ENVIRONMENTAL TEMPERATURE; FEMALE; GENETICS; GENOTYPE; INNATE IMMUNITY; LIFESPAN; LONGEVITY; MALE; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; TRAUMATIC BRAIN INJURY;

CHRONIC TRAUMATIC ENCEPHALOPATHY; CONCUSSION; INSECT;

ACCELERATION; AGE FACTORS; ANALYSIS OF VARIANCE; ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; BRAIN INJURIES; DISEASE MODELS, ANIMAL; DROSOPHILA MELANOGASTER; FEMALE; IMMUNITY, INNATE; LONGEVITY; MALE; REAL-TIME POLYMERASE CHAIN REACTION; SEX FACTORS;

EID: 84887077818     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1316895110     Document Type: Article

References (41)

1. Masel BE, DeWitt DS (2010) Traumatic brain injury: A disease process, not an event. J Neurotrauma 27(8):1529-1540.
2. Blennow K, Hardy J, Zetterberg H (2012) The neuropathology and neurobiology of traumatic brain injury. Neuron 76(5):886-899.
3. Maas AI, et al. (2012) Re-orientation of clinical research in traumatic brain injury: Report of an international workshop on comparative effectiveness research. J Neurotrauma 29(1):32-46.
4. Xiong Y, Mahmood A, Chopp M (2013) Animal models of traumatic brain injury. Nat Rev Neurosci 14(2):128-142.
5. O'Connor WT, Smyth A, Gilchrist MD (2011) Animal models of traumatic brain injury: A critical evaluation. Pharmacol Ther 130(2):106-113.
6. Lessing D, Bonini NM (2009) Maintaining the brain: Insight into human neurodegeneration from Drosophila melanogaster mutants. Nat Rev Genet 10(6):359-370.
7. Kahsai L, Zars T (2011) Learning and memory in Drosophila: Behavior, genetics, and neural systems. Int Rev Neurobiol 99:139-167.
8. Bushey D, Cirelli C (2011) From genetics to structure to function: Exploring sleep in Drosophila. Int Rev Neurobiol 99:213-244.
9. Boyan GS, Reichert H (2011) Mechanisms for complexity in the brain: Generating the insect central complex. Trends Neurosci 34(5):247-257.
10. Reichert H (2005) A tripartite organization of the urbilaterian brain: Developmental genetic evidence from Drosophila. Brain Res Bull 66(4-6):491-494.
11. Littleton JT, Ganetzky B (2000) Ion channels and synaptic organization: Analysis of the Drosophila genome. Neuron 26(1):35-43.
12. Stork T, Bernardos R, Freeman MR (2012) Analysis of glial cell development and function in Drosophila. Cold Spring Harb Protoc 2012(1):1-17.
13. DeSalvo MK, Mayer N, Mayer F, Bainton RJ (2011) Physiologic and anatomic characterization of the brain surface glia barrier of Drosophila. Glia 59(9):1322-1340.
14. Petersen AJ, Rimkus SA, Wassarman DA (2012) ATM kinase inhibition in glial cells activates the innate immune response and causes neurodegeneration in Drosophila. Proc Natl Acad Sci USA 109(11):E656-E664.
15. Fristrom D, Fristrom JW(1993) The metamorphic development of the adult epidermis. The Development of Drosophila melanogaster, eds Bate M, Martinez-Arias A (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY), pp 843-897.
16. Piyankarage SC, Featherstone DE, Shippy SA (2012) Nanoliter hemolymph sampling and analysis of individual adult Drosophila melanogaster. Anal Chem 84(10):4460-4466.
17. Faul M, Xu L, Wald MM, Coronado VG (2010) Traumatic Brain Injury in the United States: Emergency Department Visits, Hospitalizations, and Deaths (Centers for Disease Control and Prevention, National Center for Injury Prevention and Control, Atlanta). 18. Baugh CM, et al. (2012) Chronic traumatic encephalopathy: Neurodegeneration following repetitive concussive and subconcussive brain trauma. Brain Imaging Behav 6(2):244-254.
18. Hellewell SC, Morganti-Kossmann MC (2012) Guilty molecules, guilty minds? The conflicting roles of the innate immune response to traumatic brain injury. Mediators Inflamm 2012:356494.
19. Ransohoff RM, Brown MA (2012) Innate immunity in the central nervous system. J Clin Invest 122(4):1164-1171.
20. Csuka E, et al. (1999) IL-10 levels in cerebrospinal fluid and serum of patients with severe traumatic brain injury: Relationship to IL-6, TNF-alpha, TGF-beta1 and bloodbrain barrier function. J Neuroimmunol 101(2):211-221.
21. Shohami E, Bass R, Wallach D, Yamin A, Gallily R (1996) Inhibition of tumor necrosis factor alpha (TNFalpha) activity in rat brain is associated with cerebroprotection after closed head injury. J Cereb Blood Flow Metab 16(3):378-384.
22. Sullivan PG, et al. (1999) Exacerbation of damage and altered NF-kappaB activation in mice lacking tumor necrosis factor receptors after traumatic brain injury. J Neurosci 19(15):6248-6256.
23. Lemaitre B, Hoffmann J (2007) The host defense of Drosophila melanogaster. Annu Rev Immunol 25:697-743.
24. Ramsden S, Cheung YY, Seroude L (2008) Functional analysis of the Drosophila immune response during aging. Aging Cell 7(2):225-236.
25. Dardiotis E, et al. (2010) Genetic association studies in patients with traumatic brain injury. Neurosurg Focus 28(1):E9.
26. Coimbra R, Hoyt DB, Potenza BM, Fortlage D, Hollingsworth-Fridlund P (2003) Does sexual dimorphism influence outcome of traumatic brain injury patients? The answer is no!. J Trauma 54(4):689-700.
27. Hukkelhoven CW, et al. (2003) Patient age and outcome following severe traumatic brain injury: An analysis of 5600 patients. J Neurosurg 99(4):666-673.
28. Dhandapani S, Manju D, Sharma B, Mahapatra A (2012) Prognostic significance of age in traumatic brain injury. J Neurosci Rural Pract 3(2):131-135.
29. Gavett BE, Stern RA, McKee AC (2011) Chronic traumatic encephalopathy: A potential late effect of sport-related concussive and subconcussive head trauma. Clin Sports Med 30(1):179-188, xi.
30. Gavett BE, Stern RA, Cantu RC, Nowinski CJ, McKee AC (2010) Mild traumatic brain injury: A risk factor for neurodegeneration. Alzheimers Res Ther 2(3):18.
31. Al Nimer F, et al. (2013) Strain influences on inflammatory pathway activation, cell infiltration and complement cascade after traumatic brain injury in the rat. Brain Behav Immun 27(1):109-122.
32. Singleton RH, Yan HQ, Fellows-Mayle W, Dixon CE (2010) Resveratrol attenuates behavioral impairments and reduces cortical and hippocampal loss in a rat controlled cortical impact model of traumatic brain injury. J Neurotrauma 27(6):1091-1099.
33. Timmers S, Auwerx J, Schrauwen P (2012) The journey of resveratrol from yeast to human. Aging (Albany, NY Online) 4(3):146-158.
34. Guo D, Zeng L, Brody DL, Wong M (2013) Rapamycin attenuates the development of posttraumatic epilepsy in a mouse model of traumatic brain injury. PLoS ONE 8(5): e64078.
35. Johnson SC, Rabinovitch PS, Kaeberlein M (2013) mTOR is a key modulator of ageing and age-related disease. Nature 493(7432):338-345.
36. Mahley RW, Huang Y (2012) Apolipoprotein e sets the stage: Response to injury triggers neuropathology. Neuron 76(5):871-885.
37. Ang LS, Cruz RP, Hendel A, Granville DJ (2008) Apolipoprotein E, an important player in longevity and age-related diseases. Exp Gerontol 43(7):615-622.
38. Tanzi RE (2012) The genetics of Alzheimer disease. Cold Spring Harb Perspect Med 2(10):a006296, 10.1101/cshperspect.a006296.
39. McKee AC, et al. (2009) Chronic traumatic encephalopathy in athletes: Progressive tauopathy after repetitive head injury. J Neuropathol Exp Neurol 68(7):709-735.
40. Li YJ, et al. (2002) Age at onset in two common neurodegenerative diseases is genetically controlled. Am J Hum Genet 70(4):985-993.
41. Petersen AJ, Katzenberger RJ, Wassarman DA (2013) The innate immune response transcription factor relish is necessary for neurodegeneration in a Drosophila model of ataxia-telangiectasia. Genetics 194(1):133-142.