Differentiation between genomic and non-genomic feedback controls yields an HPA axis model featuring Hypercortisolism as an irreversible bistable switch

Theoretical Biology and Medical Modelling

Volumn 10, Issue 1, 2013, Pages

  Zarzer, Clemens A ^b   Puchinger, Martin G ^c   Köhler, Gottfried ^c   Kügler, Philipp ^a,b  

^a UNIVERSITY OF HOHENHEIM   (Germany)

^b JOHANN RADON INSTITUTE FOR COMPUTATIONAL AND APPLIED MATHEMATICS   (Austria)

^c MAX F PERUTZ LABORATORIES   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

MURINAE;

CORTICOTROPIN;

ARTICLE; BIOLOGICAL MODEL; CUSHING SYNDROME; FEEDBACK SYSTEM; GENETICS; HUMAN; HUMAN GENOME; HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS HYPOPHYSIS SYSTEM; METABOLISM; REGULATOR GENE;

ADRENOCORTICOTROPIC HORMONE; CUSHING SYNDROME; FEEDBACK, PHYSIOLOGICAL; GENES, SWITCH; GENOME, HUMAN; HUMANS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MODELS, BIOLOGICAL; PITUITARY-ADRENAL SYSTEM;

EID: 84887050393     PISSN: None     EISSN: 17424682     Source Type: Journal    
DOI: 10.1186/1742-4682-10-65     Document Type: Article

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