ASB2α, an E3 ubiquitin ligase specificity subunit, regulates cell spreading and triggers proteasomal degradation of filamins by targeting the filamin calponin homology 1 domain

Journal of Biological Chemistry

Volumn 288, Issue 44, 2013, Pages 32093-32105

  Razinia, Ziba ^a,b   Baldassarre, Massimiliano ^a   Cantelli, Gaia ^a,c   Calderwood, David A ^a,d  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE CANCER CENTER   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN-BINDING DOMAINS; CROSS-LINKING PROTEIN; FLOW CYTOMETRY ANALYSIS; HEMATOPOIETIC CELL DIFFERENTIATION; PROTEASOMAL DEGRADATION; SUBCELLULAR LOCALIZATIONS; TRANS-MEMBRANE PROTEINS; TRANSIENT EXPRESSION;

AMINO ACIDS; CELL ADHESION; CELLS; SCAFFOLDS (BIOLOGY);

PROTEINS;

ACTIN; ARGININE; CALPONIN; F ACTIN; FILAMIN; FILAMIN A; LYSINE; LYSINE 135; LYSINE 42; LYSINE 43; MEMBRANE PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ACTIN FILAMENT; AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CELL ADHESION; CELL DIFFERENTIATION; CELL MATURATION; CELL SPREADING; CELLULAR DISTRIBUTION; ENZYME SPECIFICITY; FLOW CYTOMETRY; HEMATOPOIETIC CELL; HUMAN; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TARGETING; SEQUENCE HOMOLOGY;

ACTIN; CALPONIN HOMOLOGY DOMAIN; CELL BIOLOGY; CYTOSKELETON; E3 UBIQUITIN LIGASE; FILAMIN; STRESS FIBER;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; FILAMINS; HEMATOPOIETIC STEM CELLS; HUMANS; MUTATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEOLYSIS; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84887045259     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.496604     Document Type: Article

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