Implication of the TRPM4 nonselective cation channel in mammalian sinus rhythm

Heart Rhythm

Volumn 10, Issue 11, 2013, Pages 1683-1689

  Hof, Thomas ^a   Simard, Christophe ^a   Rouet, René ^a   Sallé, Laurent ^a   Guinamard, Romain ^a  

^a France   (France)

Author keywords

Bradycardia; Ca2+ activated nonselective cation channel; Heart rate; Sinus node; Transient receptor potential melastatin 4

Indexed keywords

CALCIUM ION; CATION CHANNEL; SODIUM ION; TRANSIENT RECEPTOR POTENTIAL CHANNEL M4;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EXPERIMENTAL RABBIT; FEMALE; HEART BEAT; HEART DEPOLARIZATION; HEART MUSCLE POTENTIAL; HEART RATE; HEART RIGHT ATRIUM; ISOLATED HEART; MOUSE; NONHUMAN; PACEMAKER; PRIORITY JOURNAL; RAT; SINUS BRADYCARDIA; SINUS NODE; SINUS RHYTHM; SODIUM CALCIUM EXCHANGE;

ACTION POTENTIAL; ACTION POTENTIAL AMPLITUDE; ACTION POTENTIAL DURATION AT 50% REPOLARIZATION; ACTION POTENTIAL DURATION AT 70% OF REPOLARIZATION; ACTION POTENTIAL DURATION AT 90% OF REPOLARIZATION; AP; APA; APD(50); APD(70); APD(90); BRADYCARDIA; CA(2+)-ACTIVATED NONSELECTIVE CATION CHANNEL; CA(2+)-ACTIVATED NONSELECTIVE CATION CHANNELS; CONCENTRATION FOR HALF MAXIMAL EFFECT; DD; DIASTOLIC DEPOLARIZATION; EC(50); FUNNY CURRENT; HEART RATE; I(CA,L); I(CA,T); I(F); L-TYPE CA(2+) CURRENT; MAXIMUM UPSTROKE VELOCITY; NSC(CA); RESTING MEMBRANE POTENTIAL; RMP; SAN; SINOATRIAL NODE; SINUS NODE; T-TYPE CA(2+) CURRENT; TRANSIENT RECEPTOR POTENTIAL MELASTATIN; TRANSIENT RECEPTOR POTENTIAL MELASTATIN 4; TRPM; V(MAX); WILD TYPE; WT;

ANIMALS; BRADYCARDIA; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION; HEART ATRIA; HEART RATE; MICE; MICE, INBRED C57BL; PATCH-CLAMP TECHNIQUES; PHENANTHRENES; PROTEIN KINASE INHIBITORS; RABBITS; RATS; SINOATRIAL NODE; TRPM CATION CHANNELS;

EID: 84887026124     PISSN: 15475271     EISSN: 15563871     Source Type: Journal    
DOI: 10.1016/j.hrthm.2013.08.014     Document Type: Article

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