Nanoparticles of 2-deoxy-d-glucose functionalized poly(ethylene glycol)-co-poly(trimethylene carbonate) for dual-targeted drug delivery in glioma treatment

Biomaterials

Volumn 35, Issue 1, 2014, Pages 518-529

  Jiang, Xinyi ^a,b   Xin, Hongliang ^a,c   Ren, Qiuyue ^a   Gu, Jijin ^a   Zhu, Lingjun ^d   Du, Fengyi ^b   Feng, Chunlai ^b   Xie, Yike ^a   Sha, Xianyi ^a   Fang, Xiaoling ^a  

^a FUDAN UNIVERSITY   (China)

^b JIANGSU UNIVERSITY   (China)

^c NANJING MEDICAL UNIVERSITY   (China)

^d THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Avascular glioma spheroids; Dual targeted drug delivery system; Endocytic mechanism; Glioma; Glucose transporter

Indexed keywords

DRUG DELIVERY SYSTEM; ENCAPSULATION EFFICIENCY; GLIOMA; GLIOMA SPHEROIDS; GLUCOSE TRANSPORTERS; INTRAVENOUS ADMINISTRATION; NANOPARTICULATE SYSTEM; PHYSICO-CHEMICAL CHARACTERIZATION;

DRUG DELIVERY; ENCAPSULATION; ENZYME INHIBITION; MOLECULAR BIOLOGY; NANOPARTICLES; POLYETHYLENE GLYCOLS; SAFETY TESTING;

TUMORS;

CLATHRIN; DEOXYGLUCOSE; NANOPARTICLE; PACLITAXEL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BLOOD BRAIN BARRIER; CAVEOLA; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG TARGETING; ENDOCYTOSIS; FLUORESCENCE IMAGING; GLIOMA; GLIOMA CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NANOENCAPSULATION; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; TRANSCYTOSIS;

MUS;

AVASCULAR GLIOMA SPHEROIDS; DUAL-TARGETED DRUG DELIVERY SYSTEM; ENDOCYTIC MECHANISM; GLIOMA; GLUCOSE TRANSPORTER;

ANIMALS; BRAIN NEOPLASMS; CELL LINE, TUMOR; DEOXYGLUCOSE; DIOXANES; DRUG DELIVERY SYSTEMS; ENDOCYTOSIS; GLIOMA; MICE; MICROSCOPY, CONFOCAL; NANOPARTICLES; OPTICAL IMAGING; POLYETHYLENE GLYCOLS; POLYMERS; SUBCELLULAR FRACTIONS;

EID: 84887019309     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.09.094     Document Type: Article

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