Specific lipase-responsive polymer-coated gadolinium nanoparticles for MR imaging of early acute pancreatitis

Biomaterials

Volumn 35, Issue 1, 2014, Pages 356-367

  Zhang, Hong Wu ^a   Wang, Li Qin ^a   Xiang, Qing Feng ^a   Zhong, Qian ^b   Chen, Lu Ming ^c   Xu, Cai Xia ^a   Xiang, Xian Hong ^a   Xu, Bo ^a   Meng, Fei ^a   Wan, Yi Qian ^a   Deng, David Y B ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^c YALE UNIVERSITY   (United States)

Author keywords

Acute pancreatitis; Conditional activation; Diagnosis; Gadolinium; Magnetic resonance imaging; Nanoparticle

Indexed keywords

ACUTE PANCREATITIS; DIAGNOSTIC METHODS; DIAGNOSTIC TOOLS; GADOLINIUM NANOPARTICLES; LOW CYTOTOXICITIES; MRI CONTRAST AGENTS; SENSITIVITY AND SPECIFICITY; SIGNAL INTENSITIES;

AMINO ACIDS; BIOCOMPATIBILITY; DIAGNOSIS; DIAGNOSTIC PRODUCTS; GADOLINIUM; MAGNETIC RESONANCE IMAGING; NANOPARTICLES; SIGNAL SYSTEMS;

SYNTHESIS (CHEMICAL);

ARGININE; GADOLINIUM PENTETATE; NANOPARTICLE;

ACUTE PANCREATITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOCOMPATIBILITY; CONJUGATION; CONTROLLED STUDY; CYTOTOXICITY; DIAGNOSIS; DIAGNOSTIC ACCURACY; IN VITRO STUDY; IN VIVO STUDY; NANOPROBE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RAT;

RATTUS;

ACUTE PANCREATITIS; CONDITIONAL ACTIVATION; DIAGNOSIS; GADOLINIUM; MAGNETIC RESONANCE IMAGING; NANOPARTICLE;

ACUTE DISEASE; ANIMALS; EARLY DIAGNOSIS; GADOLINIUM; HEK293 CELLS; HUMANS; LIPASE; MAGNETIC RESONANCE IMAGING; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; PANCREATITIS; POLYMERS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84887016276     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.09.046     Document Type: Article

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