Gd-DTPA-loaded polymer-metal complex micelles with high relaxivity for MR cancer imaging

Biomaterials

Volumn 34, Issue 2, 2013, Pages 492-500

  Mi, Peng ^a   Cabral, Horacio ^a   Kokuryo, Daisuke ^b   Rafi, Mohammad ^c   Terada, Yasuko ^d   Aoki, Ichio ^b   Saga, Tsuneo ^b   Takehiko, Ishii ^a   Nishiyama, Nobuhiro ^c   Kataoka, Kazunori ^a,c  

^a UNIVERSITY OF TOKYO   (Japan)

^b NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d NONE   (Japan)

Author keywords

Cancer diagnosis; Drug delivery; Magnetic resonance imaging (MRI); Micelles; Polymer metal complex

Indexed keywords

BIOACTIVE MOLECULES; CANCER DIAGNOSIS; CANCER IMAGING; CIRCULATION TIME; CLINICAL APPLICATION; CONTRAST AGENT; CONTRAST ENHANCEMENT; CORE SIZE; CORE-SHELL; DIETHYLENETRIAMINE PENTA-ACETIC ACIDS; DIHYDROGEN; DRUG CARRIER; GD-DTPA; HYDRODYNAMIC DIAMETER; METAL COMPLEX FORMATION; MICELLAR STRUCTURES; NANO-DEVICES; PHYSIOLOGICAL CONDITION; POLYMER-METAL COMPLEXES; POLYMERIC MICELLE; RELAXIVITY; SELF-ASSEMBLED; SOLID TUMORS; TUMOR ACCUMULATION; TUMOR SITE;

DIAGNOSIS; DISEASES; DRUG DELIVERY; MAGNETIC RESONANCE IMAGING; MEDICAL IMAGING; METAL COMPLEXES; MICELLES; NANOSTRUCTURED MATERIALS; PLATINUM; PLATINUM COMPOUNDS; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; POLYMERS; TUMORS;

GADOLINIUM;

AMIDE; GADOLINIUM PENTETATE; MACROGOL; METAL; POLYMER; POLY{N [N' (2 AMINOETHYL) 2 AMINOETHYL]ASPARTAMIDE}; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; CIRCULATION TIME; CONTRAST ENHANCEMENT; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; HISTOPATHOLOGY; HYDRODYNAMICS; IN VITRO STUDY; IN VIVO STUDY; MICELLE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; ONCOLOGICAL PARAMETERS; PHYSIOLOGY; PRIORITY JOURNAL; SOLID TUMOR; SYNCHROTRON RADIATION; TRANSMISSION ELECTRON MICROSCOPY; TUMOR ACCUMULATION; X RAY FLUORESCENCE;

ANIMALS; CELL LINE, TUMOR; CONTRAST MEDIA; COORDINATION COMPLEXES; DRUG CARRIERS; FEMALE; GADOLINIUM DTPA; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MAGNETIC RESONANCE IMAGING; MICE; MICELLES; NEOPLASMS; POLYETHYLENE GLYCOLS; PROTEINS; TISSUE DISTRIBUTION;

EID: 84868195363     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.09.030     Document Type: Article

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