Water-soluble superparamagnetic magnetite nanoparticles with biocompatible coating for enhanced magnetic resonance imaging

ACS Nano

Volumn 5, Issue 8, 2011, Pages 6315-6324

  Xiao, Lisong ^a   Li, Jiangtian ^a   Brougham, Dermot F ^b   Fox, Eoin K ^b   Feliu, Neus ^c   Bushmelev, Alexey ^a   Schmidt, Annette ^a   Mertens, Natascha ^d   Kiessling, Fabian ^d   Valldor, Martin ^a   Fadeel, Bengt ^c   Mathur, Sanjay ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

^b DUBLIN CITY UNIVERSITY   (Ireland)

^c KAROLINSKA INSTITUTE   (Sweden)

^d RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

biocompatibility; contrast agents; magnetic nanoparticles; magnetic resonance imaging; superparamagnetic iron oxide

Indexed keywords

BIOCOMPATIBLE COATINGS; BLOOD CIRCULATION; CAPPING AGENT; CELL CULTURE MEDIUMS; CELL TEST; CHEMICAL REDUCTION; CONTRAST AGENT; CRYSTALLINITIES; DEHYDROASCORBIC ACID; HYDRODYNAMIC SIZE; HYDROTHERMAL CONDITIONS; IRON HYDROXIDES; MAGNETIC NANOPARTICLES; MAGNETITE NANOPARTICLES; MRI SCANNERS; PHANTOM EXPERIMENT; PHYSICOCHEMICAL ANALYSIS; STRONG CONTRAST; SUPERPARAMAGNETIC IRON OXIDES; SUPERPARAMAGNETICS; ULTRA-SMALL; VITAMIN C;

ANIMAL CELL CULTURE; BIOCOMPATIBILITY; CARDIOVASCULAR SYSTEM; CHEMICAL STABILITY; CRYSTALLITE SIZE; HYDRODYNAMICS; IRON ORES; IRON OXIDES; MAGNETIC RESONANCE IMAGING; NANOPARTICLES; ORE REDUCTION; RESONANCE; SATURATION MAGNETIZATION; SCANNING; SUPERPARAMAGNETISM; SUSPENSIONS (FLUIDS);

NANOMAGNETICS;

BIOMATERIAL; CONTRAST MEDIUM; DEHYDROASCORBIC ACID; DIAGNOSTIC AGENT; MAGNETITE NANOPARTICLE; WATER;

ARTICLE; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; CYTOLOGY; DRUG EFFECT; HUMAN; MACROPHAGE; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; SOLUBILITY; SUSPENSION;

BIOCOMPATIBLE MATERIALS; CELL SURVIVAL; CONTRAST MEDIA; DEHYDROASCORBIC ACID; HUMANS; MACROPHAGES; MAGNETIC RESONANCE IMAGING; MAGNETITE NANOPARTICLES; MODELS, MOLECULAR; MOLECULAR CONFORMATION; SOLUBILITY; SUSPENSIONS; WATER;

EID: 80052064775     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn201348s     Document Type: Article

References (47)

1. Laurent, S.; Forge, D.; Port, M.; Roch, A.; Robic, C.; Vander, L.; Muller, R. Magnetic Iron Oxide Nanoparticles: Synthesis, Stabilization, Vectorization, Physicochemical Characterizations, and Biological Applications Chem. Rev. 2008, 108, 2064-2110
2. Gupta, A. K.; Gupta, M. Synthesis and Surface Engineering of Iron Oxide Nanoparticles for Biomedical Applications Biomaterials 2005, 26, 3995-4021 (Pubitemid 40044762)
3. LaConte, L.; Nitin, N.; Bao, G. Magnetic Nanoparticle Probes Mater. Today 2005, 8, 32-38 (Pubitemid 40574412)
4. 1 MR Contrast Agent Based on Ultrasmall PEGylated Iron Oxide Nanoparticles Nano Lett. 2009, 9, 4434-4440
5. Jun, Y.; Lee, J.; Cheon, J. Chemical Design of Nanoparticle Probes for High-Performance Magnetic Resonance Imaging Angew. Chem., Int. Ed. 2008, 47, 5122-5135
6. 2 Nanoparticles via Bioinspired Silification for Magnetic Resonance Imaging Adv. Funct. Mater. 2010, 20, 722-731
7. Sun, C.; Du, K.; Fang, C.; Bhattarai, N.; Veiseh, O.; Kievit, F.; Stephen, Z.; Lee, D.; Ellenbogen, R. G.; Ratner, B. et al. PEG-Mediated Synthesis of Highly Dispersive Multifunctional Superparamagnetic Nanoparticles: Their Physicochemical Properties and Function in Vivo ACS Nano 2010, 4, 2402-2410
8. Huang, J.; Bu, L.; Xie, J.; Chen, K.; Cheng, Z.; Li, X.; Chen, X. Effects of Nanoparticle Size on Cellular Uptake and Liver MRI with Polyvinylpyrrolidone-Coated Iron Oxide Nanoparticles ACS Nano 2010, 4, 7151-7160
9. Basly, B.; Felder-Flesch, D.; Perriat, P.; Billotey, C.; Taleb, J.; Pourroy, G.; Begin-Colin, S. Dendronized Iron Oxide Nanoparticles as Contrast Agents for MRI Chem. Commun. 2010, 46, 985-987
10. Bruns, O. T.; Ittrich, H.; Peldschus, K.; Kaul, M. G.; Tromsdorf, U. I.; Lauterwasser, J.; Nikolic, M. S.; Mollwitz, B.; Merkel, M.; Bigall, N. C. et al. Real-time Magnetic Resonance Imaging and Quantification of Liporotein Metabolism In Vivo Using Nanocrystals Nat. Nanotechnol. 2009, 4, 193-201
11. Kunzmann, A.; Andersson, B.; Thurnherr, T.; Krug, H.; Scheynius, A.; Fadeel, B. Toxicology of Engineered Nanomaterials: Focus on Biocompatibility, Biodistribution and Biodegradation Biochim. Biophys. Acta 2011, 1810, 361-371
12. Sun, S.; Zeng, H. Size-Controlled Synthesis of Magnetite Nanoparticles J. Am. Chem. Soc. 2002, 124, 8204-8205 (Pubitemid 34875378)
13. 4 (M = Fe, Co, Mn) Nanoparticles J. Am. Chem. Soc. 2004, 126, 273-279 (Pubitemid 38090367)
14. Park, J.; An, K.; Hwang, Y.; Park, J.; Noh, H.; Kim, J.; Park, J.; Hwang, N.; Hyeon, T. Ultra-large-scale Syntheses of Monodisperse Nanocrystals Nat. Mater. 2004, 3, 891-895
15. Jeong, U.; Teng, X.; Wang, Y.; Yang, H.; Xia, Y. Superparamagnetic Colloids: Controlled Synthesis and Niche Applications Adv. Mater. 2007, 19, 33-60 (Pubitemid 46144809)
16. Hu, F.; MacRenaris, K.; Waters, E. A.; Liang, T.; Schultz-Sikma, E. A.; Eckermann, A. L.; Meade, T. J. Ultrasmall, Water-Soluble Magnetite Nanoparticles with High Relaxivity for Magnetic Resonance Imaging J. Phys. Chem. C 2009, 113, 20855-20860
17. Wan, J.; Cai, W.; Meng, X.; Liu, E. Monodisperse Water-Soluble Magnetite Nanoparticles Prepared by Polyol Process for High-performance Magnetic Resonance Imaging Chem. Commun. 2007, 47, 5004-5006 (Pubitemid 350199436)
18. Ge, J.; Hu, Y.; Biasini, M.; Dong, C.; Guo, J.; Beyermann, W. P.; Yin, Y. One-step Synthesis of Highly Water-Soluble Magnetite Colloidal Nanocrystals Chem.-Eur. J. 2007, 13, 7153-7161 (Pubitemid 47340362)
19. Hu, F.; Wei, L.; Zhou, Z.; Ran, Y. L.; Li, Z.; Gao, M. Y. Preparation of Biocompatible Magnetite Nanocrzstals for In Vivo Magnetic Resonance Detection of Cancer Adv. Mater. 2006, 18, 2553-2556 (Pubitemid 44563472)
20. Jia, X.; Chen, D.; Jiao, X.; Zhai, S. Environmentally-friendly Preparation of Water-Dispersible Magnetite Nanoparticles Chem. Commun. 2009, 8, 968-970
21. Jain, T. K.; Richey, J.; Strand, M.; Leslie-Pelecky, D. L.; Flask, C. A.; Labhasetwar, V. Magnetic Nanoparticles with Dual Functional Properties: Drug Delivery and Magnetic Resonance Imaging Biomaterials 2008, 29, 4012-4021
22. 2 Contrast Agent Adv. Mater. 2007, 19, 1874-1878 (Pubitemid 47167437)
23. Hofmann, A.; Thierbach, S.; Semisch, A.; Hartwig, A.; Taupitz, M.; Ruhl, E.; Graf, C. Highly Monodisperse Water-dispersable Iron Oxide Nanoparticles for Biomedical Applications J. Mater. Chem. 2010, 20, 7842-7853
24. Cheng, D.; Hong, G.; Wang, W.; Yuan, R.; Ai, H.; Shen, J.; Liang, B.; Gao, J.; Shuai, X. Nonclustered Magnetite Nanoparticle Encapsulated Biodegradable Polymeric Micelles with Enhanced Properties for In Vivo Tumor Imaging. J. Mater. Chem. 2011, DOI: 10.1039/C0JM03783D.
25. Wang, Y.; Wong, J. F.; Teng, X. W.; Lin, X. Z.; Yang, H. Pulling" Nanoparticles into Water: Phase Transfer of Oleic Acid Stabilized Monodisperse Nanoparticles into Aqueous Solutions of α-Cyclodextrin Nano Lett. 2003, 3, 1555-1559 (Pubitemid 37518170)
26. Li, Z.; Chen, H.; Bao, H.; Gao, M. One-Pot Reaction to Synthesized Water-Soluble Magnetite Nanocrystals Chem. Mater. 2004, 16, 1391-1393
27. Li, Z.; Wei, L.; Gao, M.; Lei, Hao One-Pot Reaction to Synthesize Biocompatible Magnetite Nanoparticles Adv. Mater. 2005, 17, 1001-1005 (Pubitemid 40584337)
28. Xiao, L.; Shen, H.; von Hagen, R.; Pan, J.; Belkoura, L.; Mathur, S. Chem. Commun. 2010, 46, 6509-6511
29. Kokoh, K. B.; Hahn, F.; Metayer, A.; Lamy, C. FTIR Spectroelectrochemical Investigation of the Electrocatalytic Oxidation of Ascorbic Acid at Platinum Electrodes in Acid Medium Electrochim. Acta 2002, 47, 3965-3969 (Pubitemid 34974800)
30. Panicker, C. Y.; Varghese, H. T.; Philip, D. FT-IR, FT-Raman and SERS Spectra of Vitamin C Spectrochim. Acta A 2006, 65, 802-804 (Pubitemid 44499123)
31. 4 Nanocrystals Prepared by a 'One-Pot' Reaction J. Phys. Chem. B 2008, 112, 14390-14394
32. Aslam, M.; Schultz, E. A.; Sun, T.; Meade, T.; Dravid, V. P. Synthesis of Amine-stabilized Aqueous Colloidal Iron Oxide Nanoparticles Cryst. Growth Des. 2007, 7, 471-475
33. Roca, A. G.; Morales, M. P.; O'Grady, K.; Serna, C. J. Structural and Magnetic Properties of Uniform Magnetite Nanoparticles Prepared by High Temperature Decomposition of Organic Precursors Nanotechnology 2006, 17, 2783-2788 (Pubitemid 43814928)
34. Roca, A. G.; Niznansky, D.; Poltierova-Vejpravova, J.; Bittova, B.; González-Fernández, M. A.; Serna, C. J.; Morales, M. P. Magnetite Nanoparticles with no Surface Spin Canting J. Appl. Phys. 2009, 105, 114309-114315
35. Demortière, A.; Panissod, P.; Pichon, B. P.; Pourroy, G.; Guillon, D.; Donnio, B.; Bégin-Colin, S. Size-dependent Properties of Magnetic Iron Oxide Nanocrystals Nanoscale 2011, 3, 225-232
36. 2-Contrast Agents for Magnetic Resonance Imaging Adv. Funct. Mater. 2009, 19, 2319-2324
37. 1 Magnetic Resonance Imaging Contrast Agents for Molecular Imaging Langmuir 2007, 3, 4583-4588 (Pubitemid 46643193)
38. Stolarczyk, J.; Ghosh, S.; Brougham, D. F. Controlled Growth of Nanoparticle Clusters through Competitive Stabilizer Desorption Angew. Chem., Int. Ed. 2009, 48, 175-178
39. Roch, A.; Muller, R. N.; Gillis, P. Theory of Proton Relaxation Induced by Superparamagnetic Particles J. Chem. Phys. 1999, 110, 5403-5411 (Pubitemid 129615822)
40. Meledandri, C. J.; Stolarczyk, J. K.; Ghosh, S.; Brougham, D. F. Nonaqueous Magnetic Nanoparticle Suspensions with Controlled Particle Size and Nuclear Magnetic Resonance Properties Langmuir 2008, 24, 14159-14165
41. Corr, S. A.; Gun'ko, Y. K.; Tekoriute, R.; Meledandri, C. J.; Brougham, D. F. Poly(sodium-4-styrene) sulfonate-Iron Oxide Nanocomposite Dispersions with Controlled Magnetic Resonance Properties J. Phys. Chem. C 2008, 112, 13324-13327
42. Frankamp, B. L.; Boal, A. K.; Tuominen, M. T.; Rotello, V. M. Direct Control of the Magnetic Interaction between Iron Oxide Nanoparticles through Dendrimer-Mediated Selfassembly J. Am. Chem. Soc. 2005, 127, 9731-9735 (Pubitemid 40984009)
43. Chen, Y.; Chen, H.; Zeng, D.; Tian, Y.; Chen, F.; Feng, J.; Shi, J. Core/Shell Structured Hollow Mesoporous Nanocapsules; A Potential Platform for Simultaneous Cell Imaging and Anticancer Drug Delivery ACS Nano 2010, 4, 6001-6013
44. Vallhov, H.; Qin, J.; Johansson, S. M.; Ahlborg, N.; Muhammed, M.; Scheynius, A.; Gabrielsson, S. The Importance of An Endotoxin-free Environment During the Production of Nanoparticles Used in Medical Applications Nano Lett. 2006, 6, 1682-1686 (Pubitemid 44327531)
45. Braydich-Stolle, L.; Speshock, J.; Castle, A.; Smith, M.; Murdock, R. C.; Hussain, S. M. Nanosized Aluminum Altered Immune Function ACS Nano 2010, 4, 3661-3670
46. Witasp, E.; Kupferschmidt, N.; Bengtsson, L.; Hultenby, K.; Smedman, C.; Paulie, S.; Garcia-Bennett, A.; Fadeel, B. Efficient Internalization of Mesoporous Silica Particles of Different Sizes by Primary Human Macrophages without Impairment of Macrophage Clearance of Apoptotic or Antibody-opsonized Target Cells Toxicol. Appl. Pharmacol. 2009, 239, 306-19
47. Meledandri, C. J.; Ninjbadgar, T.; Brougham, D. F. Size-controlled Magnetoliposomes with Tunable Magnetic Resonance Relaxation Enhancements J. Mater. Chem. 2011, 21, 214-222