메뉴 건너뛰기




Volumn 4, Issue 8, 2009, Pages

Human mesenchymal stem cells self-renew and differentiate according to a deterministic hierarchy

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL RENEWAL; CLONOGENESIS; CONNECTIVE TISSUE; CONTROLLED STUDY; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; OSSIFICATION; UMBILICAL CORD; Y CHROMOSOME; CELL CULTURE; CELL DIVISION; CYTOLOGY;

EID: 68349128436     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0006498     Document Type: Article
Times cited : (209)

References (55)
  • 1
    • 0017119380 scopus 로고
    • Fibroblast precursors in normal and irradiated mouse hematopoietic organs
    • Friedenstein AJ, Gorskaja JF, Kulagina NN (1976) Fibroblast precursors in normal and irradiated mouse hematopoietic organs. Exp Hematol 4: 267-274.
    • (1976) Exp Hematol , vol.4 , pp. 267-274
    • Friedenstein, A.J.1    Gorskaja, J.F.2    Kulagina, N.N.3
  • 2
    • 0018947660 scopus 로고
    • Characterization of human bone marrow fibroblast colony-forming cells (CFUF) and their progeny
    • Castro-Malaspina H, Gay RE, Resnick G, Kapoor N, Meyers P, et al. (1980) Characterization of human bone marrow fibroblast colony-forming cells (CFUF) and their progeny. Blood 56: 289-301.
    • (1980) Blood , vol.56 , pp. 289-301
    • Castro-Malaspina, H.1    Gay, R.E.2    Resnick, G.3    Kapoor, N.4    Meyers, P.5
  • 3
    • 0030938134 scopus 로고    scopus 로고
    • Factors required for bone marrow stromal fibroblast colony formation in vitro
    • Kuznetsov SA, Friedenstein AJ, Robey PG (1997) Factors required for bone marrow stromal fibroblast colony formation in vitro. Br J Haematol 97: 561-570.
    • (1997) Br J Haematol , vol.97 , pp. 561-570
    • Kuznetsov, S.A.1    Friedenstein, A.J.2    Robey, P.G.3
  • 4
    • 0030763497 scopus 로고    scopus 로고
    • Single-colony derived strains of human marrow stromal fibroblasts form bone after transplantation in vivo
    • Kuznetsov SA, Krebsbach PH, Satomura K, Kerr J, Riminucci M, et al. (1997) Single-colony derived strains of human marrow stromal fibroblasts form bone after transplantation in vivo. J Bone Miner Res 12: 1335-1347.
    • (1997) J Bone Miner Res , vol.12 , pp. 1335-1347
    • Kuznetsov, S.A.1    Krebsbach, P.H.2    Satomura, K.3    Kerr, J.4    Riminucci, M.5
  • 6
    • 0035043970 scopus 로고    scopus 로고
    • Adipogenic potential of human adipose derived stromal cells from multiple donors is heterogeneous
    • Sen A, Lea-Currie YR, Sujkowska D, Franklin DM, Wilkison WO, et al. (2001) Adipogenic potential of human adipose derived stromal cells from multiple donors is heterogeneous. J Cell Biochem 81: 312-319.
    • (2001) J Cell Biochem , vol.81 , pp. 312-319
    • Sen, A.1    Lea-Currie, Y.R.2    Sujkowska, D.3    Franklin, D.M.4    Wilkison, W.O.5
  • 7
    • 0034605069 scopus 로고    scopus 로고
    • Clonal isolation of muscle-derived cells capable of enhancing muscle regeneration and bone healing
    • Lee JY, Qu-Petersen Z, Cao B, Kimura S, Jankowski R, et al. (2000) Clonal isolation of muscle-derived cells capable of enhancing muscle regeneration and bone healing. Journal of Cell Biology 150: 1085-1100.
    • (2000) Journal of Cell Biology , vol.150 , pp. 1085-1100
    • Lee, J.Y.1    Qu-Petersen, Z.2    Cao, B.3    Kimura, S.4    Jankowski, R.5
  • 9
    • 4444317343 scopus 로고    scopus 로고
    • Effects of osteogenic induction on mesenchymal cells from fetal and maternal parts of human placenta
    • Takahashi K, Igura K, Zhang X, Mitsuru A, Takahashi TA (2004) Effects of osteogenic induction on mesenchymal cells from fetal and maternal parts of human placenta. Cell Transplantation 13: 337-341.
    • (2004) Cell Transplantation , vol.13 , pp. 337-341
    • Takahashi, K.1    Igura, K.2    Zhang, X.3    Mitsuru, A.4    Takahashi, T.A.5
  • 10
    • 13744254666 scopus 로고    scopus 로고
    • Human umbilical cord perivascular (HUCPV) cells: A source of mesenchymal progenitors
    • Sarugaser R, Lickorish D, Baksh D, Hosseini MM, Davies JE (2005) Human umbilical cord perivascular (HUCPV) cells: a source of mesenchymal progenitors. Stem Cells 23: 220-229.
    • (2005) Stem Cells , vol.23 , pp. 220-229
    • Sarugaser, R.1    Lickorish, D.2    Baksh, D.3    Hosseini, M.M.4    Davies, J.E.5
  • 11
    • 10444248938 scopus 로고    scopus 로고
    • Mesenchymal stem cells in the Wharton's jelly of the human umbilical cord
    • Wang HS, Hung SC, Peng ST, Huang CC, Wei HM, et al. (2004) Mesenchymal stem cells in the Wharton's jelly of the human umbilical cord. Stem Cells 22: 1330-1337.
    • (2004) Stem Cells , vol.22 , pp. 1330-1337
    • Wang, H.S.1    Hung, S.C.2    Peng, S.T.3    Huang, C.C.4    Wei, H.M.5
  • 13
    • 59749097201 scopus 로고    scopus 로고
    • Isolation, propagation, and characterization of human umbilical cord perivascular cells (HUCPVCs)
    • Sarugaser R, Ennis J, Stanford WL, Davies JE (2009) Isolation, propagation, and characterization of human umbilical cord perivascular cells (HUCPVCs). Methods Mol Biol 482: 269-279.
    • (2009) Methods Mol Biol , vol.482 , pp. 269-279
    • Sarugaser, R.1    Ennis, J.2    Stanford, W.L.3    Davies, J.E.4
  • 14
    • 36249001191 scopus 로고    scopus 로고
    • Concise review: Human umbilical cord stroma with regard to the source of fetus-derived stem cells
    • Can A, Karahuseyinoglu S (2007) Concise review: human umbilical cord stroma with regard to the source of fetus-derived stem cells. Stem Cells 25: 2886-2895.
    • (2007) Stem Cells , vol.25 , pp. 2886-2895
    • Can, A.1    Karahuseyinoglu, S.2
  • 15
    • 4444300615 scopus 로고    scopus 로고
    • Human placenta-derived cells have mesenchymal stem/progenitor cell potential
    • Fukuchi Y, Nakajima H, Sugiyama D, Hirose I, Kitamura T, et al. (2004) Human placenta-derived cells have mesenchymal stem/progenitor cell potential. Stem Cells 22: 649-658.
    • (2004) Stem Cells , vol.22 , pp. 649-658
    • Fukuchi, Y.1    Nakajima, H.2    Sugiyama, D.3    Hirose, I.4    Kitamura, T.5
  • 16
    • 33745503987 scopus 로고    scopus 로고
    • Mesenchymal stem cells reside in virtually all post-natal organs and tissues
    • da Silva Meirelles L, Chagastelles PC, Nardi NB (2006) Mesenchymal stem cells reside in virtually all post-natal organs and tissues. J Cell Sci 119: 2204-2213.
    • (2006) J Cell Sci , vol.119 , pp. 2204-2213
    • da Silva Meirelles, L.1    Chagastelles, P.C.2    Nardi, N.B.3
  • 18
    • 0031955152 scopus 로고    scopus 로고
    • Doherty MJ, Ashton BA, Walsh S, Beresford JN, Grant ME, et al. (1998) Vascular pericytes express osteogenic potential in vitro and in vivo. J Bone MinerRes 13: 828-838.
    • Doherty MJ, Ashton BA, Walsh S, Beresford JN, Grant ME, et al. (1998) Vascular pericytes express osteogenic potential in vitro and in vivo. J Bone MinerRes 13: 828-838.
  • 20
    • 50849139576 scopus 로고    scopus 로고
    • A perivascular origin for mesenchymal stem cells in multiple human organs
    • Crisan M, Yap S, Casteilla L, Chen CW, Corselli M, et al. (2008) A perivascular origin for mesenchymal stem cells in multiple human organs. Cell Stem Cell 3: 301-313.
    • (2008) Cell Stem Cell , vol.3 , pp. 301-313
    • Crisan, M.1    Yap, S.2    Casteilla, L.3    Chen, C.W.4    Corselli, M.5
  • 21
    • 0026228558 scopus 로고
    • Mesenchymal stem cells
    • Caplan AI (1991) Mesenchymal stem cells. J OrthopRes 9: 641-650.
    • (1991) J OrthopRes , vol.9 , pp. 641-650
    • Caplan, A.I.1
  • 23
    • 0030889354 scopus 로고    scopus 로고
    • Marrow stromal cells as stem cells for nonhematopoietic tissues
    • Prockop DJ (1997) Marrow stromal cells as stem cells for nonhematopoietic tissues. Science 276: 71-74.
    • (1997) Science , vol.276 , pp. 71-74
    • Prockop, D.J.1
  • 24
    • 34250854663 scopus 로고    scopus 로고
    • Neuroepithelial cells supply an initial transient wave of MSC differentiation
    • Takashima Y, Era T, Nakao K, Kondo S, Kasuga M, et al. (2007) Neuroepithelial cells supply an initial transient wave of MSC differentiation. Cell 129: 1377-1388.
    • (2007) Cell , vol.129 , pp. 1377-1388
    • Takashima, Y.1    Era, T.2    Nakao, K.3    Kondo, S.4    Kasuga, M.5
  • 25
    • 27944435821 scopus 로고    scopus 로고
    • Clarification of the nomenclature for MSC: The International Society for Cellular Therapy position statement
    • Horwitz EM, Le Blanc K, Dominici M, Mueller I, Slaper-Cortenbach I, et al. (2005) Clarification of the nomenclature for MSC: The International Society for Cellular Therapy position statement. Cytotherapy 7: 393-395.
    • (2005) Cytotherapy , vol.7 , pp. 393-395
    • Horwitz, E.M.1    Le Blanc, K.2    Dominici, M.3    Mueller, I.4    Slaper-Cortenbach, I.5
  • 26
    • 4444263350 scopus 로고    scopus 로고
    • Isolation of a highly clonogenic and multipotential subfraction of adult stem cells from bone marrow stroma
    • Smith JR, Pochampally R, Perry A, Hsu SC, Prockop DJ (2004) Isolation of a highly clonogenic and multipotential subfraction of adult stem cells from bone marrow stroma. Stem Cells 22: 823-831.
    • (2004) Stem Cells , vol.22 , pp. 823-831
    • Smith, J.R.1    Pochampally, R.2    Perry, A.3    Hsu, S.C.4    Prockop, D.J.5
  • 27
    • 0034056758 scopus 로고    scopus 로고
    • Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to a hierarchical model
    • Muraglia A, Cancedda R, Quarto R (2000) Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to a hierarchical model. Journal of Cell Science 113: 1161-1166.
    • (2000) Journal of Cell Science , vol.113 , pp. 1161-1166
    • Muraglia, A.1    Cancedda, R.2    Quarto, R.3
  • 28
  • 29
    • 35348921682 scopus 로고    scopus 로고
    • Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment
    • Sacchetti B, Funari A, Michienzi S, Di Cesare S, Piersanti S, et al. (2007) Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment. Cell 131: 324-336.
    • (2007) Cell , vol.131 , pp. 324-336
    • Sacchetti, B.1    Funari, A.2    Michienzi, S.3    Di Cesare, S.4    Piersanti, S.5
  • 30
    • 33646358697 scopus 로고    scopus 로고
    • Mesenchymal multipotency of adult human periosteal cells demonstrated by single-cell lineage analysis
    • De Bari C, Dell'Accio F, Vanlauwe J, Eyckmans J, Khan IM, et al. (2006) Mesenchymal multipotency of adult human periosteal cells demonstrated by single-cell lineage analysis. Arthritis Rheum 54: 1209-1221.
    • (2006) Arthritis Rheum , vol.54 , pp. 1209-1221
    • De Bari, C.1    Dell'Accio, F.2    Vanlauwe, J.3    Eyckmans, J.4    Khan, I.M.5
  • 31
    • 33144474684 scopus 로고    scopus 로고
    • Clonal amniotic fluid-derived stem cells express characteristics of both mesenchymal and neural stem cells
    • Tsai MS, Hwang SM, Tsai YL, Cheng FC, Lee JL, et al. (2006) Clonal amniotic fluid-derived stem cells express characteristics of both mesenchymal and neural stem cells. Biol Reprod 74: 545-551.
    • (2006) Biol Reprod , vol.74 , pp. 545-551
    • Tsai, M.S.1    Hwang, S.M.2    Tsai, Y.L.3    Cheng, F.C.4    Lee, J.L.5
  • 32
    • 1842783560 scopus 로고    scopus 로고
    • Clonal population of adult stem cells: Life span and differentiation potential
    • Seruya M, Shah A, Pedrotty D, du Laney T, Melgiri R, et al. (2004) Clonal population of adult stem cells: life span and differentiation potential. Cell Transplant 13: 93-101.
    • (2004) Cell Transplant , vol.13 , pp. 93-101
    • Seruya, M.1    Shah, A.2    Pedrotty, D.3    du Laney, T.4    Melgiri, R.5
  • 33
    • 42949100114 scopus 로고    scopus 로고
    • In vitro immunologic properties of human umbilical cord perivascular cells
    • Ennis J, Gotherstrom C, Le Blanc K, Davies JE (2008) In vitro immunologic properties of human umbilical cord perivascular cells. Cytotherapy 10: 174-181.
    • (2008) Cytotherapy , vol.10 , pp. 174-181
    • Ennis, J.1    Gotherstrom, C.2    Le Blanc, K.3    Davies, J.E.4
  • 34
    • 34547122719 scopus 로고    scopus 로고
    • Comparison of proliferative and multilineage differentiation potential of human mesenchymal stem cells derived from umbilical cord and bone marrow
    • Baksh D, Yao R, Tuan RS (2007) Comparison of proliferative and multilineage differentiation potential of human mesenchymal stem cells derived from umbilical cord and bone marrow. Stem Cells 25: 1384-1392.
    • (2007) Stem Cells , vol.25 , pp. 1384-1392
    • Baksh, D.1    Yao, R.2    Tuan, R.S.3
  • 36
    • 0028966028 scopus 로고
    • The growth factor requirements of STRO-1-positive human bone marrow stromal precursors under serum-deprived conditions in vitro
    • Gronthos S, Simmons PJ (1995) The growth factor requirements of STRO-1-positive human bone marrow stromal precursors under serum-deprived conditions in vitro. Blood 85: 929-940.
    • (1995) Blood , vol.85 , pp. 929-940
    • Gronthos, S.1    Simmons, P.J.2
  • 37
    • 0027230799 scopus 로고
    • Ultrastructural and immunohisto-chemical studies of Wharton's jelly umbilical cord cells
    • Takechi K, Kuwabara Y, Mizuno M (1993) Ultrastructural and immunohisto-chemical studies of Wharton's jelly umbilical cord cells. Placenta 14: 235-245.
    • (1993) Placenta , vol.14 , pp. 235-245
    • Takechi, K.1    Kuwabara, Y.2    Mizuno, M.3
  • 38
    • 0032504070 scopus 로고    scopus 로고
    • Study on myofibroblast differentiation in the stromal cells of Wharton's jelly Expression and localization of alpha-smooth muscle actin
    • Kobayashi K, Kubota T, Aso T (1998) Study on myofibroblast differentiation in the stromal cells of Wharton's jelly Expression and localization of alpha-smooth muscle actin. Early Human Development 51: 223-233.
    • (1998) Early Human Development , vol.51 , pp. 223-233
    • Kobayashi, K.1    Kubota, T.2    Aso, T.3
  • 39
    • 13744254666 scopus 로고    scopus 로고
    • Human umbilical cord perivascular (HUCPV) cells: A source of mesenchymal progenitors
    • Sarugaser R, Lickorish D, Baksh D, Hosseini MM, Davies JE (2005) Human umbilical cord perivascular (HUCPV) cells: a source of mesenchymal progenitors. Stem Cells 23: 220-229.
    • (2005) Stem Cells , vol.23 , pp. 220-229
    • Sarugaser, R.1    Lickorish, D.2    Baksh, D.3    Hosseini, M.M.4    Davies, J.E.5
  • 40
    • 0038379165 scopus 로고    scopus 로고
    • Rapid myeloerythroid repopulation after intrafemoral transplantation of NOD-SCID mice reveals a new class of human stem cells
    • Mazurier F, Doedens M, Gan OI, Dick JE (2003) Rapid myeloerythroid repopulation after intrafemoral transplantation of NOD-SCID mice reveals a new class of human stem cells. Nature Medicine 9: 959-963.
    • (2003) Nature Medicine , vol.9 , pp. 959-963
    • Mazurier, F.1    Doedens, M.2    Gan, O.I.3    Dick, J.E.4
  • 41
    • 56349122502 scopus 로고    scopus 로고
    • Cyclic stretch-induced TGFbeta1/Smad signaling inhibits adipogenesis in umbilical cord progenitor cells
    • Turner NJ, Jones HS, Davies JE, Canfield AE (2008) Cyclic stretch-induced TGFbeta1/Smad signaling inhibits adipogenesis in umbilical cord progenitor cells. Biochem Biophys Res Commun 377: 1147-1151.
    • (2008) Biochem Biophys Res Commun , vol.377 , pp. 1147-1151
    • Turner, N.J.1    Jones, H.S.2    Davies, J.E.3    Canfield, A.E.4
  • 42
    • 33748990080 scopus 로고    scopus 로고
    • Defining the actual sensitivity and specificity of the neurosphere assay in stem cell biology
    • Singec I, Knoth R, Meyer RP, Maciaczyk J, Volk B, et al. (2006) Defining the actual sensitivity and specificity of the neurosphere assay in stem cell biology. Nat Methods 3: 801-806.
    • (2006) Nat Methods , vol.3 , pp. 801-806
    • Singec, I.1    Knoth, R.2    Meyer, R.P.3    Maciaczyk, J.4    Volk, B.5
  • 43
    • 0023922373 scopus 로고
    • Purification and characterization of mouse hematopoietic stem cells
    • Spangrude GJ, Heimfeld S, Weissman IL (1988) Purification and characterization of mouse hematopoietic stem cells. Science 241: 58-62.
    • (1988) Science , vol.241 , pp. 58-62
    • Spangrude, G.J.1    Heimfeld, S.2    Weissman, I.L.3
  • 44
    • 0029796633 scopus 로고    scopus 로고
    • Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell
    • Osawa M, Hanada K, Hamada H, Nakauchi H (1996) Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science 273: 242-245.
    • (1996) Science , vol.273 , pp. 242-245
    • Osawa, M.1    Hanada, K.2    Hamada, H.3    Nakauchi, H.4
  • 45
    • 0025903359 scopus 로고
    • Clonal analysis of hematopoietic stem-cell differentiation in vivo
    • Smith LG, Weissman IL, Heimfeld S (1991) Clonal analysis of hematopoietic stem-cell differentiation in vivo. Proc Natl Acad Sci USA 88: 2788-2792.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 2788-2792
    • Smith, L.G.1    Weissman, I.L.2    Heimfeld, S.3
  • 46
    • 0037609723 scopus 로고    scopus 로고
    • Mesenchymal progenitor self-renewal deficiency leads to age-dependent osteoporosis in Sca-1/Ly-6A null mice
    • Bonyadi M, Waldman SD, Liu D, Aubin JE, Grynpas MD, et al. (2003) Mesenchymal progenitor self-renewal deficiency leads to age-dependent osteoporosis in Sca-1/Ly-6A null mice. Proc Natl Acad Sci USA 100: 5840-5845.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 5840-5845
    • Bonyadi, M.1    Waldman, S.D.2    Liu, D.3    Aubin, J.E.4    Grynpas, M.D.5
  • 47
    • 34547120690 scopus 로고    scopus 로고
    • Concise review: Stem cell antigen-1: expression, function, and enigma
    • Holmes C, Stanford WL (2007) Concise review: stem cell antigen-1: expression, function, and enigma. Stem Cells 25: 1339-1347.
    • (2007) Stem Cells , vol.25 , pp. 1339-1347
    • Holmes, C.1    Stanford, W.L.2
  • 48
    • 37749010464 scopus 로고    scopus 로고
    • Efficient generation of human hepatocytes by the intrahepatic delivery of clonal human mesenchymal stem cells in fetal sheep
    • Chamberlain J, Yamagami T, Colletti E, Theise ND, Desai J, et al. (2007) Efficient generation of human hepatocytes by the intrahepatic delivery of clonal human mesenchymal stem cells in fetal sheep. Hepatology 46: 1935-1945.
    • (2007) Hepatology , vol.46 , pp. 1935-1945
    • Chamberlain, J.1    Yamagami, T.2    Colletti, E.3    Theise, N.D.4    Desai, J.5
  • 50
    • 84989485234 scopus 로고
    • The development of fibroblast colonies in monolayer cultures of guinea-pig bone marrow and spleen cells
    • Friedenstein AJ, Chailakhjan RK, Lalykina KS (1970) The development of fibroblast colonies in monolayer cultures of guinea-pig bone marrow and spleen cells. Cell and Tissue Kinetics 3: 393-403.
    • (1970) Cell and Tissue Kinetics , vol.3 , pp. 393-403
    • Friedenstein, A.J.1    Chailakhjan, R.K.2    Lalykina, K.S.3
  • 51
    • 0016214539 scopus 로고
    • Precursors for fibroblasts in different populations of hematopoietic cells as detected by the in vitro colony assay method
    • Friedenstein AJ, Deriglasova UF, Kulagina NN, Panasuk AF, Rudakowa SF, et al. (1974) Precursors for fibroblasts in different populations of hematopoietic cells as detected by the in vitro colony assay method. Exp Hematol 2: 83-92.
    • (1974) Exp Hematol , vol.2 , pp. 83-92
    • Friedenstein, A.J.1    Deriglasova, U.F.2    Kulagina, N.N.3    Panasuk, A.F.4    Rudakowa, S.F.5
  • 53
    • 0042306316 scopus 로고    scopus 로고
    • Perivascular niche of postnatal mesenchymal stem cells in human bone marrow and dental pulp
    • Shi S, Gronthos S (2003) Perivascular niche of postnatal mesenchymal stem cells in human bone marrow and dental pulp. J Bone Miner Res 18: 696-704.
    • (2003) J Bone Miner Res , vol.18 , pp. 696-704
    • Shi, S.1    Gronthos, S.2
  • 54
    • 7944220831 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Potential precursors for tumor stroma and targeted-delivery vehicles for anticancer agents
    • Studeny M, Marini FC, Dembinski JL, Zompetta C, Cabreira-Hansen M, et al. (2004) Mesenchymal stem cells: potential precursors for tumor stroma and targeted-delivery vehicles for anticancer agents. J Natl Cancer Inst 96: 1593-1603.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 1593-1603
    • Studeny, M.1    Marini, F.C.2    Dembinski, J.L.3    Zompetta, C.4    Cabreira-Hansen, M.5
  • 55
    • 34948896045 scopus 로고    scopus 로고
    • Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
    • Karnoub AE, Dash AB, Vo AP, Sullivan A, Brooks MW, et al. (2007) Mesenchymal stem cells within tumour stroma promote breast cancer metastasis. Nature 449: 557-563.
    • (2007) Nature , vol.449 , pp. 557-563
    • Karnoub, A.E.1    Dash, A.B.2    Vo, A.P.3    Sullivan, A.4    Brooks, M.W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.