Iron

Present Knowledge in Nutrition: Tenth Edition

Volumn , Issue , 2012, Pages 506-520

  Aggett, Peter J ^a  

^a LANCASTER UNIVERSITY   (United Kingdom)

Author keywords

Acute phase recompartmentation of iron, a host defense restricting iron to pathogens; Anemia and physical performance, and psychomotor, immune function; Biological functions of iron, via four categories of metalloproteins; Hepatic sensory regulation of hepcidin, and interaction of HFE; Immune activation overriding iron responsive homeostasis, and anemia; Iron absorption, gastrointestinal mucosal uptake, transfer; Iron for energy metabolism, neuro and connective tissue synthesis; Iron kinetics and use, in inborn disorders; Iron status, normal erythropoiesis and function, not limited by iron supplies; Iron, systemic distribution, endogenous iron sustaining hemoglobin

Indexed keywords

EID: 84886974197     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9781119946045.ch33     Document Type: Chapter

References (38)

1. Allen, L.H., Peerson, J.M., and Olney, D.K. (2009) Provision of multiple rather than two or fewer micronutrients more effectively improves growth and other outcomes in micronutrient deficient children and adults. J Nutr 139, 1022-1030.
2. Beard, J.L., Murray-Kolb, L.E., Haas, J.D., et al. (2007) Iron absorption prediction equations lack agreement and underestimate iron absorption. J Nutr 137, 1741-1746.
3. Brownlie, T., Utermohlen, V., Hinton, P.S. et al. (2004) Tissue iron deficiency without anemia impairs adaptation in endurance capacity after aerobic training in previously untrained women. Am J Clin Nutr 79, 437-443.
4. Brunore, M. and Vallone, B. (2006) A globin for the brain. FASEB J 20, 2192-2197.
5. Connor, J.R., Wang, X-S., Allen, R.P., et al. (2009) Altered dopaminergic profile in the putamen and substantia nigra in restless leg syndrome. Brain 132, 2403-2412.
6. Conrad, M.E. and Umbriet, J.N. (2002) Pathways of iron absorption Blood Cells Mol Dis 29, 336-355.
7. Doherty, C.P. (2007) Host-pathogen interactions: the role of iron. J Nutr 137, 1341-1344.
8. Earnshaw, A.A. and Greenwood, N.N. (2010) Iron, ruthenium and osmium. In Chemistry of the Elements, 2nd Edn. Butterworth Heinemann, Oxford, pp 1070-1112.
9. European Commission Scientific Committee for Food (1993) Reports of the Scientific Committee for Food (Thirty-first series). Nutrient and Energy Intakes for the European Community 1993. http://ec.europa.eu/food/fs/sc/scf/out89.pdf.
10. European Food Safety Authority (2004) Opinion of the Scientific Panel on Dietetic Products, Nutrition and Allergies on a request from the Commission related to the Tolerable Upper Intake Level of Iron. EFSA J 125, 1-34.
11. Georgieff, M.K. (2008) The role of iron in neurodevelopment: fetal iron deficiency and the developing hippocampus. Biochem Soc Trans 36, 1267-1271.
12. Gibson, R.S. (2005) Assessment of iron status. In Principles of Nutritional Assessment, 2nd Edn. Oxford University Press, Oxford, pp. 443-476.
13. Hallberg, L. and Hulthen, L. (2002) Perspectives on iron absorption. Blood Cells Mol Dis 29, 562-573.
14. Hunt, J.M. (2002) Reversing productivity losses from iron defi-ciency: the economic case. J Nutr 132, 794-801.
15. Hurrell, R. and Egli, I. (2010) Iron bioavailability and dietary reference values. Am J Nutr 91, 1461S-1467S.
16. Institute of Medicine (2001) Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. National Academy Press, Washington, DC.
17. L ö nnerdal, B. (2009) Soybean ferritin: implications for iron status of vegetarians. Am J Clin Nutr 89, 1680S-1685S.
18. Lutter, C.K. (2008) Iron deficiency in young children in low-income countries and new approaches for its prevention. J Nutr 138, 2523-2528.
19. McCann, J.C. and Ames, B.N. (2007) An overview of evidence for a causal relation between iron deficiency during development and deficits in cognitive or behavioral function. Am J Clin Nutr 85, 931-945.
20. McDonald, S.J. and Middleton, P. (2008) Effect of timing of umbilical cord clamping of term infants on maternal and neonatal outcomes. Cochrane Database Syst Rev (2) CD004074.
21. Moos, T., Rosengren, N.T., Skjorringe, T., et al. (2007) Iron trafficking inside the brain. J Neurochem 103, 1730-1740.
22. Nemeth, E. and Ganz, T. (2009) The role of hepcidin in iron metabolism. Acta Haematol 122, 78-86.
23. OMIM (2012) Online Mendelian Inheritance in Man. www.omim.org.
24. Pietrangelo, A. (2004) Heriditary hemochromatosis-a new look at an old disease. N Engl J Med 350, 2383-2397.
25. Richardson, D.R., Lane, D.J.R., Becker, E.M., et al. (2010) Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol. Proc Natl Acad Sci 107, 10775-10782.
26. Sachdev, H., Gera, T., and Nestel, P. (2006) Effect of iron supplementation on physical growth in children: systematic review of randomised controlled trials. Publ Health Nutr 9, 904-920.
27. Scientific Advisory Committee on Nutrition (2010) Iron and Health. The Stationery Office, London. http://www.sacn.gov.uk/pdfs/sacn_iron_and_health_report_ web.pdf.
28. Steketee, R.W. (2003) Pregnancy, nutrition and parasitic diseases. J Nutr 133, 1661S-1667S.
29. Theil, E.C. and Goss, D.J. (2009) Living with iron (and oxygen): questions and answers about iron homeostasis. Chem Rev 109, 4568-4579.
30. Troesch, B., Egli, I., Zeder, C., et al. (2009) Optimization of a phytase-containing micronutrient powder with low amounts of highly bioavailable iron for in-home fortification of complementary foods. Am J Clin Nutr 89, 539-544.
31. Weiss, G. and Goodnough, L.T. (2005) Anemia of chronic disease. N Engl J Med 35, 1011-1023.
32. World Cancer Research Fund/American Institute for Cancer Research (2007) Food, Nutrition, Physical Activity and the Prevention of Cancer: a Global Perspective. AICR, Washington, DC.
33. World Health Organization/Centers for Disease Control and Prevention (2004) Assessing the Iron Status of Populations. WHO, Geneva.
34. World Health Organization/Food and Agricultural Organization of the United Nations (2006) Guidelines on Food Fortification with Micronutrients. WHO, Geneva.
35. World Health Organization/UNICEF (2006) Joint Statement: Iron supplementation of young children in regions where malaria transmission is intense and infectious disease highly prevalent. www.who.int/nutrition/publications/WHOStatement_%20 iron%20suppl.pdf.
36. Ye, H. and Rouault, T.A (2010) Human iron-sulfur cluster assembly, cellular iron homeostasis and disease. Biochemistry 49, 4945-4956.
37. Zehetner, A.A., Orr, N., Buckmaster, A., et al. (2010) Iron supplementation for breath-holding attacks in children. Cochrane Database Syst Rev CD008132.
38. Ziegler, E.E., Nelson, S.E., and Jeter, J.M. (2009) Iron supplementation of breastfed infants from an early age. Am J Clin Nutr 89, 525-532.