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Volumn 36, Issue 6, 2008, Pages 1267-1271

The role of iron in neurodevelopment: Fetal iron deficiency and the developing hippocampus

Author keywords

Brain; Development; Fetal iron deficiency; Hippocampus; Iron; Memory

Indexed keywords

IRON; MONOAMINE;

EID: 59149091750     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST0361267     Document Type: Article
Times cited : (150)

References (47)
  • 1
    • 0035150385 scopus 로고    scopus 로고
    • Defining iron-deficiency anemia in public health terms: A time for reflection
    • Stoltzfus, R.J. (2001) Defining iron-deficiency anemia in public health terms: a time for reflection. J. Nutr. 131, 565S-567S
    • (2001) J. Nutr , vol.131
    • Stoltzfus, R.J.1
  • 2
    • 59249095170 scopus 로고    scopus 로고
    • World Health Organization (1998) Micronutrient deficiencies, http://www.who.int/nutrition/topics/ida/en/index.html
    • (1998) Micronutrient deficiencies
  • 3
    • 33750841283 scopus 로고    scopus 로고
    • Iron deficiency and brain development
    • Lozoff, B. and Georgieff, M.K. (2006) Iron deficiency and brain development. Semin. Pediatr. Neurol. 13, 158-65
    • (2006) Semin. Pediatr. Neurol , vol.13 , pp. 158-165
    • Lozoff, B.1    Georgieff, M.K.2
  • 4
    • 0028202461 scopus 로고
    • Deferoxamine posttreatment reduces ischemic brain injury in neonatal rats
    • Palmer, C., Roberts, R.L. and Bero, C. (1994) Deferoxamine posttreatment reduces ischemic brain injury in neonatal rats. Stroke 25, 1039-1045
    • (1994) Stroke , vol.25 , pp. 1039-1045
    • Palmer, C.1    Roberts, R.L.2    Bero, C.3
  • 5
    • 0035221585 scopus 로고    scopus 로고
    • Developmental science and the media: Early brain development
    • Thompson, R.A. and Nelson, C.A. (2001) Developmental science and the media: early brain development. Am. Psychol. 56, 5-15
    • (2001) Am. Psychol , vol.56 , pp. 5-15
    • Thompson, R.A.1    Nelson, C.A.2
  • 6
    • 0029973761 scopus 로고    scopus 로고
    • The role of nutrition in the development of normal cognition
    • Kretchmer, N., Beard, J.L. and Carlson, S. (1996) The role of nutrition in the development of normal cognition. Am. J. Clin. Nutr. 63, 977-1001
    • (1996) Am. J. Clin. Nutr , vol.63 , pp. 977-1001
    • Kretchmer, N.1    Beard, J.L.2    Carlson, S.3
  • 7
    • 59249095025 scopus 로고    scopus 로고
    • The role of nutrition in cognitive development
    • 2nd edn Nelson, C.A. and Luciana, M, eds, pp, MIT Press, Cambridge, MA, U.S.A
    • Fuglestad, A., Rao, R. and Georgieff, M.K. (2008) The role of nutrition in cognitive development. in Handbook of Developmental Cognitive Neuroscience, 2nd edn (Nelson, C.A. and Luciana, M., eds), pp. 623-642, MIT Press, Cambridge, MA, U.S.A.
    • (2008) Handbook of Developmental Cognitive Neuroscience , pp. 623-642
    • Fuglestad, A.1    Rao, R.2    Georgieff, M.K.3
  • 8
    • 34547753552 scopus 로고    scopus 로고
    • The assessment of newborn iron stores at birth: A review of the literature and standards for ferritin concentrations
    • Siddappa, A.J., Rao, R., Long, J.D., Widness, J.A. and Georgieff, M.K. (2007) The assessment of newborn iron stores at birth: a review of the literature and standards for ferritin concentrations. Neonatology 92, 73-82
    • (2007) Neonatology , vol.92 , pp. 73-82
    • Siddappa, A.J.1    Rao, R.2    Long, J.D.3    Widness, J.A.4    Georgieff, M.K.5
  • 10
  • 11
    • 0026580959 scopus 로고
    • Fetal iron and cytochrome c status after intrauterine hypoxemia and erythropoietin administration
    • Georgieff, M.K., Schmidt, R.L., Mills, M.M., Radmer, W.J. and Widness, J.A. (1992) Fetal iron and cytochrome c status after intrauterine hypoxemia and erythropoietin administration. Am. J. Physiol. 262, R485-R491
    • (1992) Am. J. Physiol , vol.262
    • Georgieff, M.K.1    Schmidt, R.L.2    Mills, M.M.3    Radmer, W.J.4    Widness, J.A.5
  • 13
    • 0033638119 scopus 로고    scopus 로고
    • Neurophysiologic evaluation of auditory recognition memory in healthy newborn infants and infants of diabetic mothers
    • deRegnier, R.A., Nelson, C.A., Thomas, K., Wewerka, S. and Georgieff, M.K. (2000) Neurophysiologic evaluation of auditory recognition memory in healthy newborn infants and infants of diabetic mothers. J. Pediatr. 137, 777-784
    • (2000) J. Pediatr , vol.137 , pp. 777-784
    • deRegnier, R.A.1    Nelson, C.A.2    Thomas, K.3    Wewerka, S.4    Georgieff, M.K.5
  • 14
    • 33751215360 scopus 로고
    • The ontogeny of human memory
    • Nelson, C.A. (1995) The ontogeny of human memory. Dev. Psychol. 31, 723-738
    • (1995) Dev. Psychol , vol.31 , pp. 723-738
    • Nelson, C.A.1
  • 15
    • 16444380593 scopus 로고    scopus 로고
    • Relation of neonatal iron status to individual variability in neonatal temperament
    • Wachs, T.D., Pollitt, E., Cuerto, S., Jacoby, E. and Creed-Kanishiro, H. (2005) Relation of neonatal iron status to individual variability in neonatal temperament. Dev. Psychobiol. 46, 141-153
    • (2005) Dev. Psychobiol , vol.46 , pp. 141-153
    • Wachs, T.D.1    Pollitt, E.2    Cuerto, S.3    Jacoby, E.4    Creed-Kanishiro, H.5
  • 16
    • 33750608234 scopus 로고    scopus 로고
    • Effects of iron deficiency in infancy on patterns of motor development over time
    • Shifir, T., Angulo-Barroso, R., Calatroni, A., Jimenez, E. and Lozoff, B. (2006) Effects of iron deficiency in infancy on patterns of motor development over time. Hum. Mov. Sci. 25, 821-838
    • (2006) Hum. Mov. Sci , vol.25 , pp. 821-838
    • Shifir, T.1    Angulo-Barroso, R.2    Calatroni, A.3    Jimenez, E.4    Lozoff, B.5
  • 17
    • 10244277947 scopus 로고    scopus 로고
    • Iron status and neurobehavioral development of premature infants
    • Armony-Sivan, R., Eidelman, A., Lanir, A., Sredni, D. and Yehuda, S. (2004) Iron status and neurobehavioral development of premature infants. J. Perinatol. 24, 757-762
    • (2004) J. Perinatol , vol.24 , pp. 757-762
    • Armony-Sivan, R.1    Eidelman, A.2    Lanir, A.3    Sredni, D.4    Yehuda, S.5
  • 18
  • 19
    • 33846878629 scopus 로고    scopus 로고
    • Cord serum ferritin concentrations and mental and psychomotor development of children at five years of age
    • Tamura, T., Goldenberg, R.L., Hou, J., Johnston, K.E., Cliver, S.P., Ramey, S.L. and Nelson, K.G. (2002) Cord serum ferritin concentrations and mental and psychomotor development of children at five years of age. J. Pediatr. 186, 458-463
    • (2002) J. Pediatr , vol.186 , pp. 458-463
    • Tamura, T.1    Goldenberg, R.L.2    Hou, J.3    Johnston, K.E.4    Cliver, S.P.5    Ramey, S.L.6    Nelson, K.G.7
  • 20
    • 59249105084 scopus 로고    scopus 로고
    • Long-term consequences of prenatal iron deficiency due to diabetes mellitus on children's explicit memory performance
    • in the press
    • DeBoer, T., Miller, N.C., Bauer, P.J., Georgieff, M.K. and Nelson, C.A. (2008) Long-term consequences of prenatal iron deficiency due to diabetes mellitus on children's explicit memory performance. Pediatr. Res., in the press
    • (2008) Pediatr. Res
    • DeBoer, T.1    Miller, N.C.2    Bauer, P.J.3    Georgieff, M.K.4    Nelson, C.A.5
  • 21
    • 34548836369 scopus 로고    scopus 로고
    • Dissociating the long-term effects of fetal/neonatal iron deficiency on three types of learning in the rat
    • Schmidt, A.T., Waldow, K.J., Grove, W.M., Salinas, J.A. and Georgieff, M.K. (2007) Dissociating the long-term effects of fetal/neonatal iron deficiency on three types of learning in the rat. Behav. Neurosci. 121, 475-482
    • (2007) Behav. Neurosci , vol.121 , pp. 475-482
    • Schmidt, A.T.1    Waldow, K.J.2    Grove, W.M.3    Salinas, J.A.4    Georgieff, M.K.5
  • 23
    • 0022464750 scopus 로고
    • Biochemical basis for the manifestations of iron deficiency
    • Dallman, P.R. (1986) Biochemical basis for the manifestations of iron deficiency. Annu. Rev. Nutr. 6, 13-40
    • (1986) Annu. Rev. Nutr , vol.6 , pp. 13-40
    • Dallman, P.R.1
  • 24
    • 0002097481 scopus 로고
    • Iron dependent enzymes in the brain
    • Youdim, M.B.H, ed, pp, Taylor and Francis, New York
    • Wigglesworth, J.M. and Baum, H. (1988) Iron dependent enzymes in the brain. in Brain Iron: Neurochemical and Behavioural Aspects (Youdim, M.B.H., ed.), pp. 25-66, Taylor and Francis, New York
    • (1988) Brain Iron: Neurochemical and Behavioural Aspects , pp. 25-66
    • Wigglesworth, J.M.1    Baum, H.2
  • 25
    • 0041534373 scopus 로고    scopus 로고
    • Iron status and neural functioning
    • Beard, J.L. and Connor, J.R. (2003) Iron status and neural functioning. Annu. Rev. Nutr. 23, 41-58
    • (2003) Annu. Rev. Nutr , vol.23 , pp. 41-58
    • Beard, J.L.1    Connor, J.R.2
  • 26
    • 0033944836 scopus 로고    scopus 로고
    • Perinatal iron de.ciency decreases cytochrome c oxidase (CytOx) activity in selected regions of neonatal rat brain
    • DeUngria, M., Rao, R., Wobken, J.D., Luciana, M., Nelson, C.A. and Georgieff, M.K. (2000) Perinatal iron de.ciency decreases cytochrome c oxidase (CytOx) activity in selected regions of neonatal rat brain. Pediatr. Res. 48, 169-176
    • (2000) Pediatr. Res , vol.48 , pp. 169-176
    • DeUngria, M.1    Rao, R.2    Wobken, J.D.3    Luciana, M.4    Nelson, C.A.5    Georgieff, M.K.6
  • 27
    • 42449116711 scopus 로고    scopus 로고
    • Selective impairment of cognitive performance in the young monkey following recovery from iron deficiency
    • Lubach, G.R. and Coe, C.L. (2008) Selective impairment of cognitive performance in the young monkey following recovery from iron deficiency. J. Dev. Behav. Pediatr. 29, 11-17
    • (2008) J. Dev. Behav. Pediatr , vol.29 , pp. 11-17
    • Lubach, G.R.1    Coe, C.L.2
  • 28
    • 0141639898 scopus 로고    scopus 로고
    • Perinatal iron deficiency alters the neurochemical profile of the developing rat hippocampus
    • Rao, R., Tkac, I., Townsend, E.L., Gruetter, R. and Georgieff, M.K. (2003) Perinatal iron deficiency alters the neurochemical profile of the developing rat hippocampus. J. Nutr. 133, 3215-3221
    • (2003) J. Nutr , vol.133 , pp. 3215-3221
    • Rao, R.1    Tkac, I.2    Townsend, E.L.3    Gruetter, R.4    Georgieff, M.K.5
  • 29
    • 34247102590 scopus 로고    scopus 로고
    • Gestational and lactational iron deficiency alters the developing striatal metabolome and associated behaviors in young rats
    • Ward, K.L., Tkac, I., Jing, Y., Felt, B., Beard, J., Connor, J., Schallert, T., Georgieff, M.K. and Rao, R. (2007) Gestational and lactational iron deficiency alters the developing striatal metabolome and associated behaviors in young rats. J. Nutr. 137, 1043-1049
    • (2007) J. Nutr , vol.137 , pp. 1043-1049
    • Ward, K.L.1    Tkac, I.2    Jing, Y.3    Felt, B.4    Beard, J.5    Connor, J.6    Schallert, T.7    Georgieff, M.K.8    Rao, R.9
  • 30
    • 0022536857 scopus 로고
    • Iron deficiency alters discrete proteins in rat caudate nucleus and nucleus accumbens
    • Youdim, M.B.H., Sills, M.A., Heydorn, W.E., Creed, G.J. and Jacobowitz, D.M. (1986) Iron deficiency alters discrete proteins in rat caudate nucleus and nucleus accumbens. J. Neurochem. 47, 794-799
    • (1986) J. Neurochem , vol.47 , pp. 794-799
    • Youdim, M.B.H.1    Sills, M.A.2    Heydorn, W.E.3    Creed, G.J.4    Jacobowitz, D.M.5
  • 31
    • 0030174825 scopus 로고    scopus 로고
    • Relationship of iron to oligodendrocytes and myelination
    • Connor, J.R. and Menzies, S.L. (1996) Relationship of iron to oligodendrocytes and myelination. Glia 17, 83-93
    • (1996) Glia , vol.17 , pp. 83-93
    • Connor, J.R.1    Menzies, S.L.2
  • 32
    • 0344395069 scopus 로고    scopus 로고
    • Pre- and postweaning iron deficiency alters myelination in Sprague-Dawley rats
    • Beard, J.L., Wiesinger, J.A. and Connor, J.R. (2003) Pre- and postweaning iron deficiency alters myelination in Sprague-Dawley rats. Dev. Neurosci. 25, 308-315
    • (2003) Dev. Neurosci , vol.25 , pp. 308-315
    • Beard, J.L.1    Wiesinger, J.A.2    Connor, J.R.3
  • 33
    • 0036615456 scopus 로고    scopus 로고
    • An integrative, multidisciplinary approach to the study of brain-behavior relations in the context of typical and atypical development
    • Nelson, C.A., Bloom, F.E., Cameron, J.L., Amaral, D., Dahl, R.E. and Pine, D. (2002) An integrative, multidisciplinary approach to the study of brain-behavior relations in the context of typical and atypical development. Dev. Psychopathol. 14, 499-520
    • (2002) Dev. Psychopathol , vol.14 , pp. 499-520
    • Nelson, C.A.1    Bloom, F.E.2    Cameron, J.L.3    Amaral, D.4    Dahl, R.E.5    Pine, D.6
  • 34
    • 30644464058 scopus 로고    scopus 로고
    • Transcriptional profiling of the developing rat brain reveals that the most dramatic regional differentiation in gene expression occurs postpartum
    • Stead, J.D., Neal, C., Meng, F., Wang, Y., Evans, S., Vazquez, D.M., Watson, S.J. and Akil, H. (2006) Transcriptional profiling of the developing rat brain reveals that the most dramatic regional differentiation in gene expression occurs postpartum. J. Neurosci. 26, 345-353
    • (2006) J. Neurosci , vol.26 , pp. 345-353
    • Stead, J.D.1    Neal, C.2    Meng, F.3    Wang, Y.4    Evans, S.5    Vazquez, D.M.6    Watson, S.J.7    Akil, H.8
  • 35
    • 1342280471 scopus 로고    scopus 로고
    • Perinatal iron deficiency alters apical dendritic growth in hippocampal CA1 pyramidal neurons
    • Jorgenson, L.A., Wobken, J.D. and Georgieff, M.K. (2003) Perinatal iron deficiency alters apical dendritic growth in hippocampal CA1 pyramidal neurons. Dev. Neurosci. 25, 412-420
    • (2003) Dev. Neurosci , vol.25 , pp. 412-420
    • Jorgenson, L.A.1    Wobken, J.D.2    Georgieff, M.K.3
  • 36
  • 37
    • 30344478580 scopus 로고    scopus 로고
    • Fetal iron deficiency disrupts the maturation of synaptic function and efficacy in area CA1 of the developing rat hippocampus
    • Jorgenson, L.A., Sun, M., O'Conner, M. and Georgieff, M.K. (2005) Fetal iron deficiency disrupts the maturation of synaptic function and efficacy in area CA1 of the developing rat hippocampus. Hippocampus 15, 1094-1102
    • (2005) Hippocampus , vol.15 , pp. 1094-1102
    • Jorgenson, L.A.1    Sun, M.2    O'Conner, M.3    Georgieff, M.K.4
  • 38
    • 43249100646 scopus 로고    scopus 로고
    • Perinatal nutritional iron deficiency impairs hippocampus-dependent trace eyeblink conditioning in rats
    • McEchron, M.D., Alexander, D.N., Gilmartin, M.R. and Paronish, M.D. (2008) Perinatal nutritional iron deficiency impairs hippocampus-dependent trace eyeblink conditioning in rats. Dev. Neurosci. 30, 243-254
    • (2008) Dev. Neurosci , vol.30 , pp. 243-254
    • McEchron, M.D.1    Alexander, D.N.2    Gilmartin, M.R.3    Paronish, M.D.4
  • 39
    • 0030001813 scopus 로고    scopus 로고
    • Brain iron and behavior of rats are not normalized by treatment of iron deficiency anemia during early development
    • Felt, B.T. and Lozoff, B. (1996) Brain iron and behavior of rats are not normalized by treatment of iron deficiency anemia during early development. J. Nutr. 126, 693-701
    • (1996) J. Nutr , vol.126 , pp. 693-701
    • Felt, B.T.1    Lozoff, B.2
  • 40
    • 34548075903 scopus 로고    scopus 로고
    • Perinatal ID results in altered developmental expression of genes mediating energy metabolism and neuronal morphogenesis in hippocampus
    • Carlson, E.S., Stead, J.D.H., Neal, C.R., Petryk, A. and Georgieff, M.K. (2007) Perinatal ID results in altered developmental expression of genes mediating energy metabolism and neuronal morphogenesis in hippocampus. Hippocampus 17, 678-691
    • (2007) Hippocampus , vol.17 , pp. 678-691
    • Carlson, E.S.1    Stead, J.D.H.2    Neal, C.R.3    Petryk, A.4    Georgieff, M.K.5
  • 41
    • 33847038824 scopus 로고    scopus 로고
    • The growing role of mTOR in neuronal development and plasticity
    • Jaworski, J. and Sheng, M. (2006) The growing role of mTOR in neuronal development and plasticity. Mol. Neurobiol. 34, 205-219
    • (2006) Mol. Neurobiol , vol.34 , pp. 205-219
    • Jaworski, J.1    Sheng, M.2
  • 42
    • 59249107311 scopus 로고    scopus 로고
    • Altered neurotrophic factor expression and hippocampal neuron differentiation in early-life iron deficiency anemia
    • in the press
    • Tran, P.V., Carlson, S.E., Fretham, S.J.B. and Georgieff, M.K. (2008) Altered neurotrophic factor expression and hippocampal neuron differentiation in early-life iron deficiency anemia. J. Nutr., in the press
    • (2008) J. Nutr
    • Tran, P.V.1    Carlson, S.E.2    Fretham, S.J.B.3    Georgieff, M.K.4
  • 43
    • 0019788115 scopus 로고
    • Postnatal ontogenesis of hippocampal CA1 area in rats: Development of dendritic arborisation in pyramidal neurons
    • Pokorny, J. and Yamamoto, T. (1981) Postnatal ontogenesis of hippocampal CA1 area in rats: development of dendritic arborisation in pyramidal neurons. Brain Res. Bull. 7, 113-120
    • (1981) Brain Res. Bull , vol.7 , pp. 113-120
    • Pokorny, J.1    Yamamoto, T.2
  • 44
    • 0035155874 scopus 로고    scopus 로고
    • Variations in dietary iron alter behavior in developing rats
    • Pinero, D., Jones, B. and Beard, J. (2001) Variations in dietary iron alter behavior in developing rats. J. Nutr. 131, 311-318
    • (2001) J. Nutr , vol.131 , pp. 311-318
    • Pinero, D.1    Jones, B.2    Beard, J.3
  • 45
    • 4444273210 scopus 로고    scopus 로고
    • Effect of manipulation of iron storage, transport, or availability on myelin composition and brain iron content in three different animal models
    • Ortiz, E., Pasquini, J.M., Thompson, K., Felt, B., Butkus, G., Beard, J. and Connor, J.R. (2004) Effect of manipulation of iron storage, transport, or availability on myelin composition and brain iron content in three different animal models. J. Neurosci. Res. 77, 681-689
    • (2004) J. Neurosci. Res , vol.77 , pp. 681-689
    • Ortiz, E.1    Pasquini, J.M.2    Thompson, K.3    Felt, B.4    Butkus, G.5    Beard, J.6    Connor, J.R.7
  • 46
    • 33745402807 scopus 로고    scopus 로고
    • Persistent neurochemicalJ. Nutr. and behavioral abnormalities in adulthood despite early iron supplementation for perinatal iron deficiency anemia in rats
    • Felt, B.T., Beard, J.L., Schallert, T., Shao, J., Aldridge, J.W., Connor, J.R., Georgieff, M.K. and Lozoff, B. (2006) Persistent neurochemicalJ. Nutr. and behavioral abnormalities in adulthood despite early iron supplementation for perinatal iron deficiency anemia in rats. Behav. Brain Res. 171, 261-270
    • (2006) Behav. Brain Res , vol.171 , pp. 261-270
    • Felt, B.T.1    Beard, J.L.2    Schallert, T.3    Shao, J.4    Aldridge, J.W.5    Connor, J.R.6    Georgieff, M.K.7    Lozoff, B.8
  • 47
    • 0342546002 scopus 로고    scopus 로고
    • Phosphorylation of microtubule-associated protein 2 (MAP2) and its relevance for the regulation of the neuronal cytoskeleton function
    • Sánchez, C., Díaz-Nido, J. and Avila, J. (2000) Phosphorylation of microtubule-associated protein 2 (MAP2) and its relevance for the regulation of the neuronal cytoskeleton function. Prog. Neurobiol. 61, 133-168
    • (2000) Prog. Neurobiol , vol.61 , pp. 133-168
    • Sánchez, C.1    Díaz-Nido, J.2    Avila, J.3


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