-
1
-
-
23044510839
-
Growth regulation of the vascular system: An emerging role for adenosine
-
Adair TH (2005) Growth regulation of the vascular system: An emerging role for adenosine. Am J Physiol Regul Integr Comp Physiol 289:R283-R296
-
(2005)
Am J Physiol Regul Integr Comp Physiol
, vol.289
, pp. R283-R296
-
-
Adair, T.H.1
-
2
-
-
0345060347
-
Adenosinergic protection of dopaminergic and GABAergic neurons against mitochondrial inhibition through receptors located in the substantia nigra and striatum, respectively
-
Al fi nito PD, Wang SP, Manzino L, Rijhsinghani S, Zeevalk GD, Sonsalla PK (2003) Adenosinergic protection of dopaminergic and GABAergic neurons against mitochondrial inhibition through receptors located in the substantia nigra and striatum, respectively. J Neurosci 23:10982-10987
-
(2003)
J Neurosci
, vol.23
, pp. 10982-10987
-
-
Al Fi Nito, P.D.1
Wang, S.P.2
Manzino, L.3
Rijhsinghani, S.4
Zeevalk, G.D.5
Sonsalla, P.K.6
-
5
-
-
0034950069
-
Prospective study of caffeine consumption and risk of Parkinson's disease in men and women
-
Ascherio A, Zhang SM, Hernán MA, Kawachi I, Colditz GA, Speizer FE, Willett WC (2001) Prospective study of caffeine consumption and risk of Parkinson's disease in men and women. Ann Neurol 50:56-63
-
(2001)
Ann Neurol
, vol.50
, pp. 56-63
-
-
Ascherio, A.1
Zhang, S.M.2
Hernán, M.A.3
Kawachi, I.4
Colditz, G.A.5
Speizer, F.E.6
Willett, W.C.7
-
6
-
-
73549111772
-
Urate as a predictor of the rate of clinical decline in Parkinson disease
-
Ascherio A, LeWitt PA, Xu K, Eberly S, Watts A, Matson WR, Marras C, Kieburtz K, Rudolph A, Bogdanov MB et al (2009) Urate as a predictor of the rate of clinical decline in Parkinson disease. Arch Neurol 66:1460-1468
-
(2009)
Arch Neurol
, vol.66
, pp. 1460-1468
-
-
Ascherio, A.1
Lewitt, P.A.2
Xu, K.3
Eberly, S.4
Watts, A.5
Matson, W.R.6
Marras, C.7
Kieburtz, K.8
Rudolph, A.9
Bogdanov, M.B.10
-
7
-
-
0042626108
-
Adenosine A (2A) receptor antagonist treatment of Parkinson's disease
-
Bara-Jimenez W, Sherzai A, Dimitrova T, Favit A, Bibbiani F, Gillespie M, Morris MJ, Mouradian MM, Chase TN (2003) Adenosine A (2A) receptor antagonist treatment of Parkinson's disease. Neurology 61:293-296
-
(2003)
Neurology
, vol.61
, pp. 293-296
-
-
Bara-Jimenez, W.1
Sherzai, A.2
Dimitrova, T.3
Favit, A.4
Bibbiani, F.5
Gillespie, M.6
Morris, M.J.7
Mouradian, M.M.8
Chase, T.N.9
-
8
-
-
0042141599
-
A 2A antagonist prevents dopamine agonist-induced motor complications in animal models of Parkinson's disease
-
Bibbiani F, Oh JD, Petzer JP, Castagnoli N Jr, Chen JF, Schwarzschild MA, Chase TN (2003) A 2A antagonist prevents dopamine agonist-induced motor complications in animal models of Parkinson's disease. Exp Neurol 184:285-294
-
(2003)
Exp Neurol
, vol.184
, pp. 285-294
-
-
Bibbiani, F.1
Oh, J.D.2
Petzer, J.P.3
Castagnoli, N.4
Chen, J.F.5
Schwarzschild, M.A.6
Chase, T.N.7
-
9
-
-
78649742114
-
A randomized, double-blind, placebo-controlled cross-over trial of the adenosine A 2A antagonist SYN115 in Parkinson disease
-
Black KJ, Campbell MC, Dickerson W, Creech ML, Koller JM, Chung S, Bandak SI (2010) A randomized, double-blind, placebo-controlled cross-over trial of the adenosine A 2A antagonist SYN115 in Parkinson disease. Neurology 74(Suppl 2):A317
-
(2010)
Neurology
, vol.74
, pp. A317
-
-
Black, K.J.1
Campbell, M.C.2
Dickerson, W.3
Creech, M.L.4
Koller, J.M.5
Chung, S.6
Bandak, S.I.7
-
10
-
-
23944467999
-
Neuroprotection induced by the adenosine A 2A antagonist CSC in the 6-OHDA rat model of parkinsonism: Effect on the activity of striatal output pathways
-
Bové J, Serrats J, Mengod G, Cortés R, Tolosa E, Marin C (2005) Neuroprotection induced by the adenosine A 2A antagonist CSC in the 6-OHDA rat model of parkinsonism: effect on the activity of striatal output pathways. Exp Brain Res 165:362-374
-
(2005)
Exp Brain Res
, vol.165
, pp. 362-374
-
-
Bové, J.1
Serrats, J.2
Mengod, G.3
Cortés, R.4
Tolosa, E.5
Marin, C.6
-
11
-
-
33646005191
-
Reversion of levodopa-induced motor fl uctuations by the A 2A antagonist CSC is associated with an increase in striatal preprodynorphin mRNA expression in 6-OHDA-lesioned rats
-
Bové J, Serrats J, Mengod G, Cortés R, Aguilar E, Marin C (2006) Reversion of levodopa-induced motor fl uctuations by the A 2A antagonist CSC is associated with an increase in striatal preprodynorphin mRNA expression in 6-OHDA-lesioned rats. Synapse 59:435-444
-
(2006)
Synapse
, vol.59
, pp. 435-444
-
-
Bové, J.1
Serrats, J.2
Mengod, G.3
Cortés, R.4
Aguilar, E.5
Marin, C.6
-
12
-
-
0037333666
-
Staging of brain pathology related to sporadic Parkinson's disease
-
Braak H, Del Tredici K, Rüb U, de Vos RA, Jansen Steur EN, Braak E (2003) Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol Aging 24:197-211
-
(2003)
Neurobiol Aging
, vol.24
, pp. 197-211
-
-
Braak, H.1
Del Tredici, K.2
Rüb, U.3
De Vos, R.A.4
Jansen Steur, E.N.5
Braak, E.6
-
13
-
-
77957724387
-
Positron emission tomography (PET) study of preladenant in healthy male subjects
-
Brooks DJ, Warrington S, Tendolkar A, Cutler DL, Hunter J (2009) Positron emission tomography (PET) study of preladenant in healthy male subjects. Mov Disord 24(suppl 1):S257
-
(2009)
Mov Disord
, vol.24
, pp. S257
-
-
Brooks, D.J.1
Warrington, S.2
Tendolkar, A.3
Cutler, D.L.4
Hunter, J.5
-
14
-
-
77951087570
-
An open-label, positron emission tomography study to assess adenosine A2A brain receptor occupancy of vipadenant (BIIB014) at steady-state levels in healthy male volunteers
-
Brooks DJ, Papapetropoulos S, Vandenhende F, Tomic D, He P, Coppell A, O'Neill G (2010) An open-label, positron emission tomography study to assess adenosine A2A brain receptor occupancy of vipadenant (BIIB014) at steady-state levels in healthy male volunteers. Clin Neuropharmacol 33:55-60
-
(2010)
Clin Neuropharmacol
, vol.33
, pp. 55-60
-
-
Brooks, D.J.1
Papapetropoulos, S.2
Vandenhende, F.3
Tomic, D.4
He, P.5
Coppell, A.6
O'neill, G.7
-
15
-
-
2442595210
-
Increased adenosine A 2A receptors in the brain of Parkinson's disease patients with dyskinesias
-
Calon F, Dridi M, Hornykiewicz O, Bedard PJ, Rajput AH, Di Paolo T (2004) Increased adenosine A 2A receptors in the brain of Parkinson's disease patients with dyskinesias. Brain 127:1075-1084
-
(2004)
Brain
, vol.127
, pp. 1075-1084
-
-
Calon, F.1
Dridi, M.2
Hornykiewicz, O.3
Bedard, P.J.4
Rajput, A.H.5
Di Paolo, T.6
-
16
-
-
33748313455
-
Association of caffeine to MDMA does not increase antinociception but potentiates adverse effects of this recreational drug
-
Camarasa J, Pubill D, Escubedo E (2006) Association of caffeine to MDMA does not increase antinociception but potentiates adverse effects of this recreational drug. Brain Res 1111:72-82
-
(2006)
Brain Res
, vol.1111
, pp. 72-82
-
-
Camarasa, J.1
Pubill, D.2
Escubedo, E.3
-
17
-
-
34548538764
-
Striatal adenosine A 2A and cannabinoid CB 1 receptors form functional heteromeric complexes that mediate the motor effects of cannabinoids
-
Carriba P, Ortiz O, Patkar K, Justinova Z, Stroik J, Themann A, Müller C, Woods AS, Hope BT, Ciruela F et al (2007) Striatal adenosine A 2A and cannabinoid CB 1 receptors form functional heteromeric complexes that mediate the motor effects of cannabinoids. Neuropsychopharmacology 32:2249-2259
-
(2007)
Neuropsychopharmacology
, vol.32
, pp. 2249-2259
-
-
Carriba, P.1
Ortiz, O.2
Patkar, K.3
Justinova, Z.4
Stroik, J.5
Themann, A.6
Müller, C.7
Woods, A.S.8
Hope, B.T.9
Ciruela, F.10
-
18
-
-
0037013695
-
Differential regulation of GAD67, enkephalin and dynorphin mRNAs by chronic-intermittent L-DOPA and A 2A receptor blockade plus L-DOPA in dopamine-denervated rats
-
Carta AR, Pinna A, Cauli O, Morelli M (2002) Differential regulation of GAD67, enkephalin and dynorphin mRNAs by chronic-intermittent L-DOPA and A 2A receptor blockade plus L-DOPA in dopamine-denervated rats. Synapse 44:166-174
-
(2002)
Synapse
, vol.44
, pp. 166-174
-
-
Carta, A.R.1
Pinna, A.2
Cauli, O.3
Morelli, M.4
-
19
-
-
0344442731
-
Selective modi fi cations in GAD67 mRNA levels in striatonigral and striatopallidal pathways correlate to dopamine agonist priming in 6-hydroxydopamine-lesioned rats
-
Carta AR, Fenu S, Pala P, Tronci E, Morelli M (2003) Selective modi fi cations in GAD67 mRNA levels in striatonigral and striatopallidal pathways correlate to dopamine agonist priming in 6-hydroxydopamine-lesioned rats. Eur J Neurosci 18:2563-2572
-
(2003)
Eur J Neurosci
, vol.18
, pp. 2563-2572
-
-
Carta, A.R.1
Fenu, S.2
Pala, P.3
Tronci, E.4
Morelli, M.5
-
20
-
-
70450219517
-
Inactivation of neuronal forebrain A 2A receptors protects dopaminergic neurons in a mouse model of Parkinson's disease
-
Carta AR, Kachroo A, Schintu N, Xu K, Schwarzschild MA, Wardas J, Morelli M (2009) Inactivation of neuronal forebrain A 2A receptors protects dopaminergic neurons in a mouse model of Parkinson's disease. J Neurochem 111:1478-1489
-
(2009)
J Neurochem
, vol.111
, pp. 1478-1489
-
-
Carta, A.R.1
Kachroo, A.2
Schintu, N.3
Xu, K.4
Schwarzschild, M.A.5
Wardas, J.6
Morelli, M.7
-
21
-
-
0344630332
-
Translating A 2A antagonist KW6002 from animal models to parkinsonian patients
-
Chase TN, Bibbiani F, Bara-Jimenez W, Dimitrova T, Oh-Lee JD (2003) Translating A 2A antagonist KW6002 from animal models to parkinsonian patients. Neurology 61:S107-S111
-
(2003)
Neurology
, vol.61
, pp. S107-S111
-
-
Chase, T.N.1
Bibbiani, F.2
Bara-Jimenez, W.3
Dimitrova, T.4
Oh-Lee, J.D.5
-
22
-
-
0033232779
-
A (2A) adenosine receptor de fi ciency attenuates brain injury induced by transient focal ischemia in mice
-
Chen JF, Huang Z, Ma J, Zhu J, Moratalla R, Standaert D, Moskowitz MA, Fink JS, Schwarzschild MA (1999) A (2A) adenosine receptor de fi ciency attenuates brain injury induced by transient focal ischemia in mice. J Neurosci 19:9192-9200
-
(1999)
J Neurosci
, vol.19
, pp. 9192-9200
-
-
Chen, J.F.1
Huang, Z.2
Ma, J.3
Zhu, J.4
Moratalla, R.5
Standaert, D.6
Moskowitz, M.A.7
Fink, J.S.8
Schwarzschild, M.A.9
-
23
-
-
0035852721
-
The role of the D (2) dopamine receptor (D (2) R) in A (2A) adenosine receptor (A (2A) R)-mediated behavioral and cellular responses as revealed by A (2A) and D (2) receptor knockout mice
-
Chen JF, Moratalla R, Impagnatiello F, Grandy DK, Cuellar B, Rubinstein M, Beilstein MA, Hackett E, Fink JS, Low MJ et al (2001a) The role of the D (2) dopamine receptor (D (2) R) in A (2A) adenosine receptor (A (2A) R)-mediated behavioral and cellular responses as revealed by A (2A) and D (2) receptor knockout mice. Proc Natl Acad Sci USA 98:1970-1975
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 1970-1975
-
-
Chen, J.F.1
Moratalla, R.2
Impagnatiello, F.3
Grandy, D.K.4
Cuellar, B.5
Rubinstein, M.6
Beilstein, M.A.7
Hackett, E.8
Fink, J.S.9
Low, M.J.10
-
24
-
-
0035874345
-
Neuroprotection by caffeine and A (2A) adenosine receptor inactivation in a model of Parkinson's disease
-
Chen JF, Xu K, Petzer JP, Staal R, Xu YH, Beilstein M, Sonsalla PK, Castagnoli K, Castagnoli N Jr, Schwarzschild MA (2001b) Neuroprotection by caffeine and A (2A) adenosine receptor inactivation in a model of Parkinson's disease. J Neurosci 21:RC143
-
(2001)
J Neurosci
, vol.21
, pp. RC143
-
-
Chen, J.F.1
Xu, K.2
Petzer, J.P.3
Staal, R.4
Xu, Y.H.5
Beilstein, M.6
Sonsalla, P.K.7
Castagnoli, K.8
Castagnoli, N.9
Schwarzschild, M.A.10
-
25
-
-
0028036368
-
Uric acid is reduced in the substantia nigra in Parkinson's disease: Effect on dopamine oxidation
-
Church WH, Ward VL (1994) Uric acid is reduced in the substantia nigra in Parkinson's disease: effect on dopamine oxidation. Brain Res Bull 33:419-425
-
(1994)
Brain Res Bull
, vol.33
, pp. 419-425
-
-
Church, W.H.1
Ward, V.L.2
-
26
-
-
77958066708
-
Urate: A novel biomarker of Parkinson's disease risk, diagnosis and prognosis
-
Cipriani S, Chen X, Schwarzschild MA (2010) Urate: A novel biomarker of Parkinson's disease risk, diagnosis and prognosis. Biomark Med 4:701-712
-
(2010)
Biomark Med
, vol.4
, pp. 701-712
-
-
Cipriani, S.1
Chen, X.2
Schwarzschild, M.A.3
-
27
-
-
33644551294
-
Presynaptic control of striatal glutamatergic neurotransmission by adenosine A 1-A 2A receptor heteromers
-
Ciruela F, Casadó V, Rodrigues RJ, Luján R, Burgueño J, Canals M, Borycz J, Rebola N, Goldberg SR, Mallol J et al (2006) Presynaptic control of striatal glutamatergic neurotransmission by adenosine A 1-A 2A receptor heteromers. J Neurosci 26:2080-2087
-
(2006)
J Neurosci
, vol.26
, pp. 2080-2087
-
-
Ciruela, F.1
Casadó, V.2
Rodrigues, R.J.3
Luján, R.4
Burgueño, J.5
Canals, M.6
Borycz, J.7
Rebola, N.8
Goldberg, S.R.9
Mallol, J.10
-
28
-
-
3242765264
-
Simultaneous blockade of adenosine A 2A and metabotropic glutamate mGlu5 receptors increase their ef fi cacy in reversing Parkinsonian de fi cits in rats
-
Coccurello R, Breysse N, Amalric M (2004) Simultaneous blockade of adenosine A 2A and metabotropic glutamate mGlu5 receptors increase their ef fi cacy in reversing Parkinsonian de fi cits in rats. Neuropsychopharmacology 29:1451-1461
-
(2004)
Neuropsychopharmacology
, vol.29
, pp. 1451-1461
-
-
Coccurello, R.1
Breysse, N.2
Amalric, M.3
-
29
-
-
0141741347
-
Parkinson's disease: Mechanisms and models
-
Dauer W, Przedborski S (2003) Parkinson's disease: mechanisms and models. Neuron 39:889-909
-
(2003)
Neuron
, vol.39
, pp. 889-909
-
-
Dauer, W.1
Przedborski, S.2
-
30
-
-
31544465246
-
Selective elimination of glutamatergic synapses on striatopallidal neurons in Parkinson disease models
-
Day M, Wang Z, Ding J, An X, Ingham CA, Shering AF, Wokosin D, Ilijic E, Sun Z, Sampson AR et al (2006) Selective elimination of glutamatergic synapses on striatopallidal neurons in Parkinson disease models. Nat Neurosci 9:251-259
-
(2006)
Nat Neurosci
, vol.9
, pp. 251-259
-
-
Day, M.1
Wang, Z.2
Ding, J.3
An, X.4
Ingham, C.A.5
Shering, A.F.6
Wokosin, D.7
Ilijic, E.8
Sun, Z.9
Sampson, A.R.10
-
31
-
-
56049092243
-
Gout and the risk of Parkinson's disease: A cohort study
-
De Vera M, Rahman MM, Rankin J, Kopec J, Gao X, Choi H (2008) Gout and the risk of Parkinson's disease: A cohort study. Arthritis Rheum 59:1549-1554
-
(2008)
Arthritis Rheum
, vol.59
, pp. 1549-1554
-
-
De Vera, M.1
Rahman, M.M.2
Rankin, J.3
Kopec, J.4
Gao, X.5
Choi, H.6
-
32
-
-
0026654719
-
Potentiation of cocaine and d-amphetamine toxicity with caffeine
-
Derlet RW, Tseng JC, Albertson TE (1992) Potentiation of cocaine and d-amphetamine toxicity with caffeine. Am J Emerg Med 10:211-216
-
(1992)
Am J Emerg Med
, vol.10
, pp. 211-216
-
-
Derlet, R.W.1
Tseng, J.C.2
Albertson, T.E.3
-
34
-
-
0034741713
-
Adenosine A 2A receptor antagonists are potential antidepressants: Evidence based on pharmacology and A 2A receptor knockout mice
-
El Yacoubi M, Ledent C, Parmentier M, Bertorelli R, Ongini E, Costentin J, Vaugeois JM (2001) Adenosine A 2A receptor antagonists are potential antidepressants: evidence based on pharmacology and A 2A receptor knockout mice. Br J Pharmacol 134:68-77
-
(2001)
Br J Pharmacol
, vol.134
, pp. 68-77
-
-
El Yacoubi, M.1
Ledent, C.2
Parmentier, M.3
Bertorelli, R.4
Ongini, E.5
Costentin, J.6
Vaugeois, J.M.7
-
35
-
-
77953618656
-
A long-term study of istradefylline in subjects with fl uctuating Parkinson's disease
-
Factor S, Mark MH, Watts R, Struck L, Mori A, Ballerini R, Sussman NM (2010) A long-term study of istradefylline in subjects with fl uctuating Parkinson's disease. Parkinsonism Relat Disord 16:423-426
-
(2010)
Parkinsonism Relat Disord
, vol.16
, pp. 423-426
-
-
Factor, S.1
Mark, M.H.2
Watts, R.3
Struck, L.4
Mori, A.5
Ballerini, R.6
Sussman, N.M.7
-
36
-
-
0030615062
-
Adenosine A 2A receptor antagonism potentiates L-DOPA-induced turning behaviour and c-fos expression in 6-hydroxydopamine-lesioned rats
-
Fenu S, Pinna A, Ongini E, Morelli M (1997) Adenosine A 2A receptor antagonism potentiates L-DOPA-induced turning behaviour and c-fos expression in 6-hydroxydopamine-lesioned rats. Eur J Pharmacol 321:143-147
-
(1997)
Eur J Pharmacol
, vol.321
, pp. 143-147
-
-
Fenu, S.1
Pinna, A.2
Ongini, E.3
Morelli, M.4
-
37
-
-
70349657144
-
Impulse control disorders and dopamine dysregulation syndrome associated with dopamine agonist therapy in Parkinson's disease
-
Fenu S, Wardas J, Morelli M (2009) Impulse control disorders and dopamine dysregulation syndrome associated with dopamine agonist therapy in Parkinson's disease. Behav Pharmacol 20:363-379
-
(2009)
Behav Pharmacol
, vol.20
, pp. 363-379
-
-
Fenu, S.1
Wardas, J.2
Morelli, M.3
-
38
-
-
74149087857
-
Istradefylline as monotherapy for Parkinson disease: Results of the 6002-US-051 trial
-
Fernandez HH, Greeley DR, Zweig RM, Wojcieszek J, Mori A, Sussman NM (2010) Istradefylline as monotherapy for Parkinson disease: results of the 6002-US-051 trial. Parkinsonism Relat Disord 16:16-20
-
(2010)
Parkinsonism Relat Disord
, vol.16
, pp. 16-20
-
-
Fernandez, H.H.1
Greeley, D.R.2
Zweig, R.M.3
Wojcieszek, J.4
Mori, A.5
Sussman, N.M.6
-
39
-
-
0030861647
-
Adenosine-dopamine receptor-receptor interactions as an integrative mechanism in the basal ganglia
-
Ferré S, Fredholm BB, Morelli M, Popoli P, Fuxe K (1997) Adenosine-dopamine receptor-receptor interactions as an integrative mechanism in the basal ganglia. Trends Neurosci 20:482-487
-
(1997)
Trends Neurosci
, vol.20
, pp. 482-487
-
-
Ferré, S.1
Fredholm, B.B.2
Morelli, M.3
Popoli, P.4
Fuxe, K.5
-
40
-
-
0037015027
-
Synergistic interaction between adenosine A 2A and glutamate mGlu5 receptors: Implications for striatal neuronal function
-
Ferré S, Karcz-Kubicha M, Hope BT, Popoli P, Burgueno J, Gutierrez MA, Casadó V, Fuxe K, Goldberg SR, Lluis C et al (2002) Synergistic interaction between adenosine A 2A and glutamate mGlu5 receptors: implications for striatal neuronal function. Proc Natl Acad Sci USA 99:11940-11945
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 11940-11945
-
-
Ferré, S.1
Karcz-Kubicha, M.2
Hope, B.T.3
Popoli, P.4
Burgueno, J.5
Gutierrez, M.A.6
Casadó, V.7
Fuxe, K.8
Goldberg, S.R.9
Lluis, C.10
-
41
-
-
78650654063
-
Neuroprotective and anti-in fl ammatory effects of the adenosine A (2A) receptor antagonist ST1535 in a MPTP mouse model of Parkinson's disease
-
Frau L, Borsini F, Wardas J, Khairnar AS, Schintu N, Morelli M (2011) Neuroprotective and anti-in fl ammatory effects of the adenosine A (2A) receptor antagonist ST1535 in a MPTP mouse model of Parkinson's disease. Synapse 65:181-188
-
(2011)
Synapse
, vol.65
, pp. 181-188
-
-
Frau, L.1
Borsini, F.2
Wardas, J.3
Khairnar, A.S.4
Schintu, N.5
Morelli, M.6
-
42
-
-
0345561561
-
Actions of caffeine in the brain with special reference to factors that contribute to its widespread use
-
Fredholm BB, Bättig K, Holmén J, Nehlig A, Zvartau EE (1999) Actions of caffeine in the brain with special reference to factors that contribute to its widespread use. Pharmacol Rev 51(1):83-133
-
(1999)
Pharmacol Rev
, vol.51
, Issue.1
, pp. 83-133
-
-
Fredholm, B.B.1
Bättig, K.2
Holmén, J.3
Nehlig, A.4
Zvartau, E.E.5
-
43
-
-
41349103415
-
Diet, urate, and Parkinson's disease risk in men
-
Gao X, Chen H, Choi HK, Curhan G, Schwarzschild MA, Ascherio A (2008) Diet, urate, and Parkinson's disease risk in men. Am J Epidemiol 167:831-838
-
(2008)
Am J Epidemiol
, vol.167
, pp. 831-838
-
-
Gao, X.1
Chen, H.2
Choi, H.K.3
Curhan, G.4
Schwarzschild, M.A.5
Ascherio, A.6
-
44
-
-
0035330026
-
Caffeine reverses the memory disruption induced by intra-nigral MPTP-injection in rats
-
Gevaerd MS, Takahashi RN, Silveira R, Da Cunha C (2001) Caffeine reverses the memory disruption induced by intra-nigral MPTP-injection in rats. Brain Res Bull 55:101-106
-
(2001)
Brain Res Bull
, vol.55
, pp. 101-106
-
-
Gevaerd, M.S.1
Takahashi, R.N.2
Silveira, R.3
Da Cunha, C.4
-
45
-
-
33751032604
-
Working memory de fi cits in transgenic rats overexpressing human adenosine A 2A receptors in the brain
-
Giménez-Llort L, Schiffmann SN, Shmidt T, Canela L, Camón L, Wassholm M, Canals M, Terasmaa A, Fernández-Teruel A, Tobeña A et al (2007) Working memory de fi cits in transgenic rats overexpressing human adenosine A 2A receptors in the brain. Neurobiol Learn Mem 87:42-56
-
(2007)
Neurobiol Learn Mem
, vol.87
, pp. 42-56
-
-
Giménez-Llort, L.1
Schiffmann, S.N.2
Shmidt, T.3
Canela, L.4
Camón, L.5
Wassholm, M.6
Canals, M.7
Terasmaa, A.8
Fernández-Teruel, A.9
Tobeña, A.10
-
46
-
-
0344052684
-
Antiparkinsonian effect of a new selective adenosine A 2A receptor antagonist in MPTP-treated monkeys
-
Grondin R, Bédard PJ, Hadj Tahar A, Grégoire L, Mori A, Kase H (1999) Antiparkinsonian effect of a new selective adenosine A 2A receptor antagonist in MPTP-treated monkeys. Neurology 52:1673-1677
-
(1999)
Neurology
, vol.52
, pp. 1673-1677
-
-
Grondin, R.1
Bédard, P.J.2
Hadj Tahar, A.3
Grégoire, L.4
Mori, A.5
Kase, H.6
-
47
-
-
61449172156
-
Study of istradefylline in patients with Parkinson's disease on levodopa with motor fl uctuations
-
Hauser RA, Shulman LM, Trugman JM, Roberts J, Mori A, Ballerini R, Sussman NM (2008) Study of istradefylline in patients with Parkinson's disease on levodopa with motor fl uctuations. Mov Disord 23:2177-2185
-
(2008)
Mov Disord
, vol.23
, pp. 2177-2185
-
-
Hauser, R.A.1
Shulman, L.M.2
Trugman, J.M.3
Roberts, J.4
Mori, A.5
Ballerini, R.6
Sussman, N.M.7
-
48
-
-
79951720949
-
Preladenant in patients with Parkinson's disease and motor fl uctuations: A phase 2, doubleblind, randomised trial
-
Hauser RA, Cantillon M, Pourcher E, Micheli F, Mok V, Onofrj M, Huyck S, Wolski K (2011) Preladenant in patients with Parkinson's disease and motor fl uctuations: A phase 2, doubleblind, randomised trial. Lancet Neurol 10:221-229
-
(2011)
Lancet Neurol
, vol.10
, pp. 221-229
-
-
Hauser, R.A.1
Cantillon, M.2
Pourcher, E.3
Micheli, F.4
Mok, V.5
Onofrj, M.6
Huyck, S.7
Wolski, K.8
-
49
-
-
12344281073
-
New insights into adenosine-receptor-mediated immunosuppression and the role of adenosine in causing the immunode fi ciency associated with adenosine deaminase de fi ciency
-
Hersh fi eld MS (2005) New insights into adenosine-receptor-mediated immunosuppression and the role of adenosine in causing the immunode fi ciency associated with adenosine deaminase de fi ciency. Eur J Immunol 35:25-30
-
(2005)
Eur J Immunol
, vol.35
, pp. 25-30
-
-
Hersh Fi Eld, M.S.1
-
50
-
-
0035848459
-
Ultrastructural localization of adenosine A 2A receptors suggests multiple cellular sites for modulation of GABAergic neurons in rat striatum
-
Hettinger BD, Lee A, Linden J, Rosin DL (2001) Ultrastructural localization of adenosine A 2A receptors suggests multiple cellular sites for modulation of GABAergic neurons in rat striatum. J Comp Neurol 431:331-346
-
(2001)
J Comp Neurol
, vol.431
, pp. 331-346
-
-
Hettinger, B.D.1
Lee, A.2
Linden, J.3
Rosin, D.L.4
-
51
-
-
35248853826
-
The effect of caffeine to increase reaction time in the rat during a test of attention is mediated through antagonism of adenosine A 2A receptors
-
Higgins GA, Grzelak ME, Pond AJ, Cohen-Williams ME, Hodgson RA, Varty GB (2007) The effect of caffeine to increase reaction time in the rat during a test of attention is mediated through antagonism of adenosine A 2A receptors. Behav Brain Res 185:32-42
-
(2007)
Behav Brain Res
, vol.185
, pp. 32-42
-
-
Higgins, G.A.1
Grzelak, M.E.2
Pond, A.J.3
Cohen-Williams, M.E.4
Hodgson, R.A.5
Varty, G.B.6
-
52
-
-
77955058291
-
Competitive regulation of synaptic Ca 2+ in fl ux by D 2 dopamine and A 2A adenosine receptors
-
Higley MJ, Sabatini BL (2010) Competitive regulation of synaptic Ca 2+ in fl ux by D 2 dopamine and A 2A adenosine receptors. Nat Neurosci 13:958-966
-
(2010)
Nat Neurosci
, vol.13
, pp. 958-966
-
-
Higley, M.J.1
Sabatini, B.L.2
-
53
-
-
0037124032
-
Coaggregation, cointernalization, and codesensitization of adenosine A 2A receptors and dopamine D 2 receptors
-
Hillion J, Canals M, Torvinen M, Casado V, Scott R, Terasmaa A, Hansson A, Watson S, Olah ME, Mallol J et al (2002) Coaggregation, cointernalization, and codesensitization of adenosine A 2A receptors and dopamine D 2 receptors. J Biol Chem 77:18091-18097
-
(2002)
J Biol Chem
, vol.77
, pp. 18091-18097
-
-
Hillion, J.1
Canals, M.2
Torvinen, M.3
Casado, V.4
Scott, R.5
Terasmaa, A.6
Hansson, A.7
Watson, S.8
Olah, M.E.9
Mallol, J.10
-
54
-
-
67649836782
-
Characterization of the potent and highly selective A 2A receptor antagonists preladenant and SCH 412348 in rodent models of movement disorders and depression
-
Hodgson RA, Bertorelli R, Varty GB, Lachowicz JE, Forlani A, Fredduzzi S, Cohen-Williams ME, Higgins GA, Impagnatiello F, Nicolussi E et al (2009) Characterization of the potent and highly selective A 2A receptor antagonists preladenant and SCH 412348 in rodent models of movement disorders and depression. J Pharmacol Exp Ther 330:294-303
-
(2009)
J Pharmacol Exp Ther
, vol.330
, pp. 294-303
-
-
Hodgson, R.A.1
Bertorelli, R.2
Varty, G.B.3
Lachowicz, J.E.4
Forlani, A.5
Fredduzzi, S.6
Cohen-Williams, M.E.7
Higgins, G.A.8
Impagnatiello, F.9
Nicolussi, E.10
-
55
-
-
77956424883
-
Preladenant, a selective A (2A) receptor antagonist, is active in primate models of movement disorders
-
Hodgson RA, Bedard PJ, Varty GB, Kazdoba TM, Di Paolo T, Grzelak ME, Pond AJ, Hadjtahar A, Belanger N, Gregoire L et al (2010) Preladenant, a selective A (2A) receptor antagonist, is active in primate models of movement disorders. Exp Neurol 225:384-390
-
(2010)
Exp Neurol
, vol.225
, pp. 384-390
-
-
Hodgson, R.A.1
Bedard, P.J.2
Varty, G.B.3
Kazdoba, T.M.4
Di Paolo, T.5
Grzelak, M.E.6
Pond, A.J.7
Hadjtahar, A.8
Belanger, N.9
Gregoire, L.10
-
56
-
-
24944458193
-
Adenosine A 2A, but not A 1, receptors mediate the arousal effect of caffeine
-
Huang ZL, Qu WM, Eguchi N, Chen JF, Schwarzschild MA, Fredholm BB, Urade Y, Hayaishi O (2005) Adenosine A 2A, but not A 1, receptors mediate the arousal effect of caffeine. Nat Neurosci 8:858-859
-
(2005)
Nat Neurosci
, vol.8
, pp. 858-859
-
-
Huang, Z.L.1
Qu, W.M.2
Eguchi, N.3
Chen, J.F.4
Schwarzschild, M.A.5
Fredholm, B.B.6
Urade, Y.7
Hayaishi, O.8
-
57
-
-
0037378023
-
Neuroin fl ammatory processes in Parkinson's disease
-
Hunot S, Hirsch EC (2003) Neuroin fl ammatory processes in Parkinson's disease. Ann Neurol 53:S49-S58
-
(2003)
Ann Neurol
, vol.53
, pp. S49-S58
-
-
Hunot, S.1
Hirsch, E.C.2
-
58
-
-
0036020950
-
Neuroprotection by adenosine A 2A receptor blockade in experimental models of Parkinson's disease
-
Ikeda K, Kurokawa M, Aoyama S, Kuwana Y (2002) Neuroprotection by adenosine A 2A receptor blockade in experimental models of Parkinson's disease. J Neurochem 80:262-270
-
(2002)
J Neurochem
, vol.80
, pp. 262-270
-
-
Ikeda, K.1
Kurokawa, M.2
Aoyama, S.3
Kuwana, Y.4
-
59
-
-
0036048876
-
Recent developments in the pathology of Parkinson's disease
-
Jellinger KA (2002) Recent developments in the pathology of Parkinson's disease. J Neural Transm Suppl 62:347-376
-
(2002)
J Neural Transm Suppl
, vol.62
, pp. 347-376
-
-
Jellinger, K.A.1
-
60
-
-
21244440664
-
Istradefylline, a novel adenosine A 2A receptor antagonist, for the treatment of Parkinson's disease
-
Jenner P (2005) Istradefylline, a novel adenosine A 2A receptor antagonist, for the treatment of Parkinson's disease. Expert Opin Investig Drugs 14:729-738
-
(2005)
Expert Opin Investig Drugs
, vol.14
, pp. 729-738
-
-
Jenner, P.1
-
61
-
-
0022438093
-
The actions of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in animals as a model of Parkinson's disease
-
Jenner P, Marsden CD (1986) The actions of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in animals as a model of Parkinson's disease. J Neural Transm Suppl 20:11-39
-
(1986)
J Neural Transm Suppl
, vol.20
, pp. 11-39
-
-
Jenner, P.1
Marsden, C.D.2
-
62
-
-
27744450594
-
Interactions between metabotropic glutamate 5 and adenosine A 2A receptors in normal and parkinsonian mice
-
Kachroo A, Orlando LR, Grandy DK, Chen JF, Young AB, Schwarzschild MA (2005) Interactions between metabotropic glutamate 5 and adenosine A 2A receptors in normal and parkinsonian mice. J Neurosci 25:10414-10419
-
(2005)
J Neurosci
, vol.25
, pp. 10414-10419
-
-
Kachroo, A.1
Orlando, L.R.2
Grandy, D.K.3
Chen, J.F.4
Young, A.B.5
Schwarzschild, M.A.6
-
63
-
-
0031594271
-
Adenosine A 2A antagonist: A novel antiparkinsonian agent that does not provoke dyskinesia in parkinsonian monkeys
-
Kanda T, Jackson MJ, Smith LA, Pearce RK, Nakamura J, Kase H, Kuwana Y, Jenner P (1998a) Adenosine A 2A antagonist: A novel antiparkinsonian agent that does not provoke dyskinesia in parkinsonian monkeys. Ann Neurol 43:507-513
-
(1998)
Ann Neurol
, vol.43
, pp. 507-513
-
-
Kanda, T.1
Jackson, M.J.2
Smith, L.A.3
Pearce, R.K.4
Nakamura, J.5
Kase, H.6
Kuwana, Y.7
Jenner, P.8
-
64
-
-
0032563388
-
Adenosine A 2A receptors modify motor function in MPTP-treated common marmosets
-
Kanda T, Tashiro T, Kuwana Y, Jenner P (1998b) Adenosine A 2A receptors modify motor function in MPTP-treated common marmosets. Neuroreport 9:2857-2860
-
(1998)
Neuroreport
, vol.9
, pp. 2857-2860
-
-
Kanda, T.1
Tashiro, T.2
Kuwana, Y.3
Jenner, P.4
-
65
-
-
0034049544
-
Combined use of the adenosine A (2A) antagonist KW-6002 with L-DOPA or with selective D 1 or D 2 dopamine agonists increases antiparkinsonian activity but not dyskinesia in MPTPtreated monkeys
-
Kanda T, Jackson MJ, Smith LA, Pearce RK, Nakamura J, Kase H, Kuwana Y, Jenner P (2000) Combined use of the adenosine A (2A) antagonist KW-6002 with L-DOPA or with selective D 1 or D 2 dopamine agonists increases antiparkinsonian activity but not dyskinesia in MPTPtreated monkeys. Exp Neurol 162:321-327
-
(2000)
Exp Neurol
, vol.162
, pp. 321-327
-
-
Kanda, T.1
Jackson, M.J.2
Smith, L.A.3
Pearce, R.K.4
Nakamura, J.5
Kase, H.6
Kuwana, Y.7
Jenner, P.8
-
67
-
-
77953949824
-
Caffeine enhances astroglia and microglia reactivity induced by 3,4-methylenedioxymethamphetamine ('ecstasy') in mouse brain
-
Khairnar A, Plumitallo A, Frau L, Schintu N, Morelli M (2010) Caffeine enhances astroglia and microglia reactivity induced by 3,4-methylenedioxymethamphetamine ('ecstasy') in mouse brain. Neurotox Res 17:435-439
-
(2010)
Neurotox Res
, vol.17
, pp. 435-439
-
-
Khairnar, A.1
Plumitallo, A.2
Frau, L.3
Schintu, N.4
Morelli, M.5
-
68
-
-
34447651315
-
Interactions between 3,4-methylenedioxymethamphetamine, methamphetamine, ketamine, and caffeine in human intestinal Caco-2 cells and in oral administration to rats
-
Kuwayama K, Inoue H, Kanamori T, Tsujikawa K, Miyaguchi H, Iwata Y, Miyauchi S, Kamo N, Kishi T (2007) Interactions between 3,4-methylenedioxymethamphetamine, methamphetamine, ketamine, and caffeine in human intestinal Caco-2 cells and in oral administration to rats. Forensic Sci Int 170:183-188
-
(2007)
Forensic Sci Int
, vol.170
, pp. 183-188
-
-
Kuwayama, K.1
Inoue, H.2
Kanamori, T.3
Tsujikawa, K.4
Miyaguchi, H.5
Iwata, Y.6
Miyauchi, S.7
Kamo, N.8
Kishi, T.9
-
69
-
-
30444449968
-
Does contraversive circling in the 6-OHDA-lesioned rat indicate an ability to induce motor complications as well as therapeutic effects in Parkinson's disease
-
Lane EL, Cheetham SC, Jenner P (2006) Does contraversive circling in the 6-OHDA-lesioned rat indicate an ability to induce motor complications as well as therapeutic effects in Parkinson's disease Exp Neurol 197:284-290
-
(2006)
Exp Neurol
, vol.197
, pp. 284-290
-
-
Lane, E.L.1
Cheetham, S.C.2
Jenner, P.3
-
70
-
-
0027937810
-
Glutamatergic drugs in Parkinson's disease
-
Lange KW, Riederer P (1994) Glutamatergic drugs in Parkinson's disease. Life Sci 55: 2067-2075
-
(1994)
Life Sci
, vol.55
, pp. 2067-2075
-
-
Lange, K.W.1
Riederer, P.2
-
71
-
-
79960051903
-
Arousal effect of caffeine depends on adenosine A2A receptors in the shell of the nucleus accumbens
-
Lazarus M, Shen HY, Cherasse Y, Qu WM, Huang ZL, Bass CE, Winsky-Sommerer R, Semba K, Fredholm BB, Boison D, Hayaishi O, Urade Y, Chen JF (2011) Arousal effect of caffeine depends on adenosine A2A receptors in the shell of the nucleus accumbens. J Neurosci 6:10067-10075
-
(2011)
J Neurosci
, vol.6
, pp. 10067-10075
-
-
Lazarus, M.1
Shen, H.Y.2
Cherasse, Y.3
Qu, W.M.4
Huang, Z.L.5
Bass, C.E.6
Winsky-Sommerer, R.7
Semba, K.8
Fredholm, B.B.9
Boison, D.10
Hayaishi, O.11
Urade, Y.12
Chen, J.F.13
-
72
-
-
41849131038
-
Adenosine A 2A receptor antagonist istradefylline (KW-6002) reduces off time in Parkinson's disease: A double-blind, randomized, multicenter clinical trial (6002-US-005)
-
LeWitt PA, Guttman M, Tetrud JW, Tuite PJ, Mori A, Chaikin P, Sussman NM (2008) Adenosine A 2A receptor antagonist istradefylline (KW-6002) reduces OFF time in Parkinson's disease: A double-blind, randomized, multicenter clinical trial (6002-US-005). Ann Neurol 63:295-302
-
(2008)
Ann Neurol
, vol.63
, pp. 295-302
-
-
Lewitt, P.A.1
Guttman, M.2
Tetrud, J.W.3
Tuite, P.J.4
Mori, A.5
Chaikin, P.6
Sussman, N.M.7
-
73
-
-
0033390941
-
Cross talk between A(1) and A(2A) adenosine receptors in the hippocampus and cortex of young adult and old rats
-
Lopes LV, Cunha RA, Ribeiro JA (1999) Cross talk between A(1) and A(2A) adenosine receptors in the hippocampus and cortex of young adult and old rats. J Neurophysiol 82:3196-3203
-
(1999)
J Neurophysiol
, vol.82
, pp. 3196-3203
-
-
Lopes, L.V.1
Cunha, R.A.2
Ribeiro, J.A.3
-
74
-
-
2942754121
-
Cutting edge: Physiologic attenuation of proin fl ammatory transcription by the Gs protein-coupled A 2A adenosine receptor in vivo
-
Lukashev D, Ohta A, Apasov S, Chen JF, Sitkovsky M (2004) Cutting edge: physiologic attenuation of proin fl ammatory transcription by the Gs protein-coupled A 2A adenosine receptor in vivo. J Immunol 173:21-24
-
(2004)
J Immunol
, vol.173
, pp. 21-24
-
-
Lukashev, D.1
Ohta, A.2
Apasov, S.3
Chen, J.F.4
Sitkovsky, M.5
-
75
-
-
0037345646
-
Cellular and behavioural effects of the adenosine A 2A receptor antagonist KW-6002 in a rat model of l-DOPA-induced dyskinesia
-
Lundblad M, Vaudano E, Cenci MA (2003) Cellular and behavioural effects of the adenosine A 2A receptor antagonist KW-6002 in a rat model of l-DOPA-induced dyskinesia. J Neurochem 84:1398-1410
-
(2003)
J Neurochem
, vol.84
, pp. 1398-1410
-
-
Lundblad, M.1
Vaudano, E.2
Cenci, M.A.3
-
76
-
-
15244352457
-
Adenosine, glutamate and pH: Interactions and implications
-
Masino SA, Dulla CG (2005) Adenosine, glutamate and pH: interactions and implications. Neurol Res 27:149-152
-
(2005)
Neurol Res
, vol.27
, pp. 149-152
-
-
Masino, S.A.1
Dulla, C.G.2
-
77
-
-
30344471062
-
Caffeine promotes hyperthermia and serotonergic loss following co-administration of the substituted amphetamines, MDMA ("Ecstasy") and MDA ("Love")
-
McNamara R, Kerans A, O'Neill B, Harkin A (2006) Caffeine promotes hyperthermia and serotonergic loss following co-administration of the substituted amphetamines, MDMA ("Ecstasy") and MDA ("Love"). Neuropharmacology 50:69-80
-
(2006)
Neuropharmacology
, vol.50
, pp. 69-80
-
-
McNamara, R.1
Kerans, A.2
O'neill, B.3
Harkin, A.4
-
78
-
-
33846027055
-
Caffeine induces a profound and persistent tachycardia in response to MDMA ("Ecstasy") administration
-
McNamara R, Maginn M, Harkin A (2007) Caffeine induces a profound and persistent tachycardia in response to MDMA ("Ecstasy") administration. Eur J Pharmacol 555:194-198
-
(2007)
Eur J Pharmacol
, vol.555
, pp. 194-198
-
-
McNamara, R.1
Maginn, M.2
Harkin, A.3
-
79
-
-
77954994281
-
Clinical ef fi cacy of istradefylline (KW-6002) in Parkinson's disease: A randomized, controlled study
-
Mizuno Y, Hasegawa K, Kondo T, Kuno S, Yamamoto M (2010) Clinical ef fi cacy of istradefylline (KW-6002) in Parkinson's disease: A randomized, controlled study. Mov Disord 25:1437-1443
-
(2010)
Mov Disord
, vol.25
, pp. 1437-1443
-
-
Mizuno, Y.1
Hasegawa, K.2
Kondo, T.3
Kuno, S.4
Yamamoto, M.5
-
80
-
-
77955353133
-
Pathophysiological roles for purines: Adenosine, caffeine and urate
-
Morelli M, Carta AR, Kachroo A, Schwarzschild MA (2010) Pathophysiological roles for purines: Adenosine, caffeine and urate. Prog Brain Res 183:183-208
-
(2010)
Prog Brain Res
, vol.183
, pp. 183-208
-
-
Morelli, M.1
Carta, A.R.2
Kachroo, A.3
Schwarzschild, M.A.4
-
81
-
-
0037417810
-
Metabotropic mGlu5 receptors regulate adenosine A 2A receptor signaling
-
Nishi A, Liu F, Matsuyama S, Hamada M, Higashi H, Nairn AC, Greengard P (2003) Metabotropic mGlu5 receptors regulate adenosine A 2A receptor signaling. Proc Natl Acad Sci USA 100:1322-1327
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 1322-1327
-
-
Nishi, A.1
Liu, F.2
Matsuyama, S.3
Hamada, M.4
Higashi, H.5
Nairn, A.C.6
Greengard, P.7
-
82
-
-
29344464083
-
The effect of the adenosine A(2A) antagonist KW-6002 on motor and motivational processes in the rat
-
O'Neill M, Brown VJ (2006) The effect of the adenosine A(2A) antagonist KW-6002 on motor and motivational processes in the rat. Psychopharmacology (Berl) 184:46-55
-
(2006)
Psychopharmacology (Berl)
, vol.184
, pp. 46-55
-
-
O'neill, M.1
Brown, V.J.2
-
83
-
-
0033724826
-
Pathophysiology of the basal ganglia in Parkinson's disease
-
Obeso JA, Rodríguez-Oroz MC, Rodríguez M, Lanciego JL, Artieda J, Gonzalo N, Olanow CW (2000) Pathophysiology of the basal ganglia in Parkinson's disease. Trends Neurosci 23:S8-S19
-
(2000)
Trends Neurosci
, vol.23
, pp. S8-S19
-
-
Obeso, J.A.1
Rodríguez-Oroz, M.C.2
Rodríguez, M.3
Lanciego, J.L.4
Artieda, J.5
Gonzalo, N.6
Olanow, C.W.7
-
84
-
-
0036386814
-
Glutamate-mediated striatal dysregulation and the pathogenesis of motor response complications in Parkinson's disease
-
Oh JD, Chase TN (2002) Glutamate-mediated striatal dysregulation and the pathogenesis of motor response complications in Parkinson's disease. Amino Acids 23:133-139
-
(2002)
Amino Acids
, vol.23
, pp. 133-139
-
-
Oh, J.D.1
Chase, T.N.2
-
85
-
-
0035924320
-
Role of G-protein-coupled adenosine receptors in downregulation of in fl ammation and protection from tissue damage
-
Ohta A, Sitkovsky M (2001) Role of G-protein-coupled adenosine receptors in downregulation of in fl ammation and protection from tissue damage. Nature 414:916-920
-
(2001)
Nature
, vol.414
, pp. 916-920
-
-
Ohta, A.1
Sitkovsky, M.2
-
86
-
-
14544287564
-
KW-6002 protects from MPTP induced dopaminergic toxicity in the mouse
-
Pierri M, Vaudano E, Sager T, Englund U (2005) KW-6002 protects from MPTP induced dopaminergic toxicity in the mouse. Neuropharmacology 48:517-524
-
(2005)
Neuropharmacology
, vol.48
, pp. 517-524
-
-
Pierri, M.1
Vaudano, E.2
Sager, T.3
Englund, U.4
-
87
-
-
73449139510
-
Novel investigational adenosine A 2A receptor antagonists for Parkinson's disease
-
Pinna A (2009) Novel investigational adenosine A 2A receptor antagonists for Parkinson's disease. Expert Opin Investig Drugs 18:1619-1631
-
(2009)
Expert Opin Investig Drugs
, vol.18
, pp. 1619-1631
-
-
Pinna, A.1
-
88
-
-
0029666492
-
Blockade of A 2A adenosine receptors positively modulates turning behaviour and c-Fos expression induced by D 1 agonists in dopamine-denervated rats
-
Pinna A, Di Chiara G, Wardas J, Morelli M (1996) Blockade of A 2A adenosine receptors positively modulates turning behaviour and c-Fos expression induced by D 1 agonists in dopamine-denervated rats. Eur J Neurosci 8:1176-1181
-
(1996)
Eur J Neurosci
, vol.8
, pp. 1176-1181
-
-
Pinna, A.1
Di Chiara, G.2
Wardas, J.3
Morelli, M.4
-
89
-
-
0035283648
-
Motor stimulant effects of the adenosine A 2A receptor antagonist SCH 58261 do not develop tolerance after repeated treatments in 6-hydroxydopaminelesioned rats
-
Pinna A, Fenu S, Morelli M (2001) Motor stimulant effects of the adenosine A 2A receptor antagonist SCH 58261 do not develop tolerance after repeated treatments in 6-hydroxydopaminelesioned rats. Synapse 39:233-238
-
(2001)
Synapse
, vol.39
, pp. 233-238
-
-
Pinna, A.1
Fenu, S.2
Morelli, M.3
-
90
-
-
17444413762
-
New adenosine A 2A receptor antagonists: Actions on Parkinson's disease models
-
Pinna A, Volpini R, Cristalli G, Morelli M (2005) New adenosine A 2A receptor antagonists: Actions on Parkinson's disease models. Eur J Pharmacol 512:157-164
-
(2005)
Eur J Pharmacol
, vol.512
, pp. 157-164
-
-
Pinna, A.1
Volpini, R.2
Cristalli, G.3
Morelli, M.4
-
91
-
-
33646547603
-
Expression of dyskinetic movements and turning behaviour in subchronic L-DOPA 6-hydroxydopamine-treated rats is in fl uenced by the testing environment
-
Pinna A, Pontis S, Morelli M (2006) Expression of dyskinetic movements and turning behaviour in subchronic L-DOPA 6-hydroxydopamine-treated rats is in fl uenced by the testing environment. Behav Brain Res 171:175-178
-
(2006)
Behav Brain Res
, vol.171
, pp. 175-178
-
-
Pinna, A.1
Pontis, S.2
Morelli, M.3
-
92
-
-
73449102471
-
A new ethyladenine antagonist of adenosine A (2A) receptors: Behavioral and biochemical characterization as an antiparkinsonian drug
-
Pinna A, Tronci E, Schintu N, Simola N, Volpini R, Pontis S, Cristalli G, Morelli M (2010) A new ethyladenine antagonist of adenosine A (2A) receptors: behavioral and biochemical characterization as an antiparkinsonian drug. Neuropharmacology 58:613-623
-
(2010)
Neuropharmacology
, vol.58
, pp. 613-623
-
-
Pinna, A.1
Tronci, E.2
Schintu, N.3
Simola, N.4
Volpini, R.5
Pontis, S.6
Cristalli, G.7
Morelli, M.8
-
93
-
-
9744277523
-
Adenosine A 2A receptor antagonism and neuroprotection: Mechanisms, lights, and shadows
-
Popoli P, Minghetti L, Tebano MT, Pintor A, Domenici MR, Massotti M (2004) Adenosine A 2A receptor antagonism and neuroprotection: mechanisms, lights, and shadows. Crit Rev Neurobiol 16:99-106
-
(2004)
Crit Rev Neurobiol
, vol.16
, pp. 99-106
-
-
Popoli, P.1
Minghetti, L.2
Tebano, M.T.3
Pintor, A.4
Domenici, M.R.5
Massotti, M.6
-
94
-
-
1442299425
-
Opposite modulatory roles for adenosine A 1 and A 2A receptors on glutamate and dopamine release in the shell of the nucleus accumbens: Effects of chronic caffeine exposure
-
Quarta D, Ferré S, Solinas M, You ZB, Hockemeyer J, Popoli P, Goldberg SR (2004) Opposite modulatory roles for adenosine A 1 and A 2A receptors on glutamate and dopamine release in the shell of the nucleus accumbens: effects of chronic caffeine exposure. J Neurochem 88:1151-1158
-
(2004)
J Neurochem
, vol.88
, pp. 1151-1158
-
-
Quarta, D.1
Ferré, S.2
Solinas, M.3
You, Z.B.4
Hockemeyer, J.5
Popoli, P.6
Goldberg, S.R.7
-
95
-
-
34548433951
-
The neuroprotective effects of caffeine: A prospective population study (the Three City Study)
-
Ritchie K, Carrière I, de Mendonca A, Portet F, Dartigues JF, Rouaud O, Barberger-Gateau P, Ancelin ML (2007) The neuroprotective effects of caffeine: A prospective population study (the Three City Study). Neurology 69:536-545
-
(2007)
Neurology
, vol.69
, pp. 536-545
-
-
Ritchie, K.1
Carrière, I.2
De Mendonca, A.3
Portet, F.4
Dartigues, J.F.5
Rouaud, O.6
Barberger-Gateau, P.7
Ancelin, M.L.8
-
96
-
-
33748457136
-
The novel adenosine A 2A receptor antagonist ST1535 potentiates the effects of a threshold dose of L-DOPA in MPTP treated common marmosets
-
Rose S, Jackson MJ, Smith LA, Stockwell K, Johnson L, Carminati P, Jenner P (2006) The novel adenosine A 2A receptor antagonist ST1535 potentiates the effects of a threshold dose of L-DOPA in MPTP treated common marmosets. Eur J Pharmacol 546:82-87
-
(2006)
Eur J Pharmacol
, vol.546
, pp. 82-87
-
-
Rose, S.1
Jackson, M.J.2
Smith, L.A.3
Stockwell, K.4
Johnson, L.5
Carminati, P.6
Jenner, P.7
-
97
-
-
0034738134
-
Association of coffee and caffeine intake with the risk of Parkinson disease
-
Ross GW, Abbott RD, Petrovitch H, Morens DM, Grandinetti A, Tung KH, Tanner CM, Masaki KH, Blanchette PL, Curb JD et al (2000) Association of coffee and caffeine intake with the risk of Parkinson disease. JAMA 283:2674-2679
-
(2000)
JAMA
, vol.283
, pp. 2674-2679
-
-
Ross, G.W.1
Abbott, R.D.2
Petrovitch, H.3
Morens, D.M.4
Grandinetti, A.5
Tung, K.H.6
Tanner, C.M.7
Masaki, K.H.8
Blanchette, P.L.9
Curb, J.D.10
-
98
-
-
0032427295
-
Tremulous jaw movements in rats: A model of parkinsonian tremor
-
Salamone JD, Mayorga AJ, Trevitt JT, Cousins MS, Conlan A, Nawab A (1998) Tremulous jaw movements in rats: A model of parkinsonian tremor. Prog Neurobiol 56:591-611
-
(1998)
Prog Neurobiol
, vol.56
, pp. 591-611
-
-
Salamone, J.D.1
Mayorga, A.J.2
Trevitt, J.T.3
Cousins, M.S.4
Conlan, A.5
Nawab, A.6
-
99
-
-
36148983766
-
Adenosine A 2A receptors and basal ganglia physiology
-
Schiffmann SN, Fisone G, Moresco R, Cunha RA, Ferré S (2007) Adenosine A 2A receptors and basal ganglia physiology. Prog Neurobiol 83:277-292
-
(2007)
Prog Neurobiol
, vol.83
, pp. 277-292
-
-
Schiffmann, S.N.1
Fisone, G.2
Moresco, R.3
Cunha, R.A.4
Ferré, S.5
-
100
-
-
45149122797
-
Serum urate as a predictor of clinical and radiographic progression in Parkinson disease
-
Schwarzschild MA, Schwid SR, Marek K, Watts A, Lang AE, Oakes D, Shoulson I, Ascherio A, Hyson C, Parkinson Study Group PRECEPT Investigators et al (2008) Serum urate as a predictor of clinical and radiographic progression in Parkinson disease. Arch Neurol 65:716-723
-
(2008)
Arch Neurol
, vol.65
, pp. 716-723
-
-
Schwarzschild, M.A.1
Schwid, S.R.2
Marek, K.3
Watts, A.4
Lang, A.E.5
Oakes, D.6
Shoulson, I.7
Ascherio, A.8
Hyson, C.9
-
101
-
-
77954650213
-
Recent progress in the discovery of adenosine A (2A) receptor antagonists for the treatment of Parkinson's disease
-
Shah U, Hodgson R (2010) Recent progress in the discovery of adenosine A (2A) receptor antagonists for the treatment of Parkinson's disease. Curr Opin Drug Discov Devel 13:466-480
-
(2010)
Curr Opin Drug Discov Devel
, vol.13
, pp. 466-480
-
-
Shah, U.1
Hodgson, R.2
-
102
-
-
3543107307
-
Blockade of adenosine A 2A receptors antagonizes parkinsonian tremor in the rat tacrine model by an action on speci fi c striatal regions
-
Simola N, Fenu S, Baraldi PG, Tabrizi MA, Morelli M (2004) Blockade of adenosine A 2A receptors antagonizes parkinsonian tremor in the rat tacrine model by an action on speci fi c striatal regions. Exp Neurol 189:182-188
-
(2004)
Exp Neurol
, vol.189
, pp. 182-188
-
-
Simola, N.1
Fenu, S.2
Baraldi, P.G.3
Tabrizi, M.A.4
Morelli, M.5
-
103
-
-
70349192980
-
Adenosine A 2A receptor-antagonist/dopamine D 2 receptor-agonist bivalent ligands as pharmacological tools to detect A 2A-D 2 receptor heteromers
-
Soriano A, Ventura R, Molero A, Hoen R, Casadó V, Cortés A, Fanelli F, Albericio F, Lluís C, Franco R et al (2009) Adenosine A 2A receptor-antagonist/dopamine D 2 receptor-agonist bivalent ligands as pharmacological tools to detect A 2A-D 2 receptor heteromers. J Med Chem 52:5590-5602
-
(2009)
J Med Chem
, vol.52
, pp. 5590-5602
-
-
Soriano, A.1
Ventura, R.2
Molero, A.3
Hoen, R.4
Casadó, V.5
Cortés, A.6
Fanelli, F.7
Albericio, F.8
Lluís, C.9
Franco, R.10
-
104
-
-
44949229417
-
A 12-week, placebocontrolled study (6002-US-006) of istradefylline in Parkinson disease
-
Stacy M, Silver D, Mendis T, Sutton J, Mori A, Chaikin P, Sussman NM (2008) A 12-week, placebocontrolled study (6002-US-006) of istradefylline in Parkinson disease. Neurology 70:2233-2240
-
(2008)
Neurology
, vol.70
, pp. 2233-2240
-
-
Stacy, M.1
Silver, D.2
Mendis, T.3
Sutton, J.4
Mori, A.5
Chaikin, P.6
Sussman, N.M.7
-
105
-
-
33750200622
-
ST 1535: A preferential A 2A adenosine receptor antagonist
-
Stasi MA, Borsini F, Varani K, Vincenzi F, Di Cesare MA, Minetti P, Ghirardi O, Carminati P (2006) ST 1535: A preferential A 2A adenosine receptor antagonist. Int J Neuropsychopharmacol 9:575-584
-
(2006)
Int J Neuropsychopharmacol
, vol.9
, pp. 575-584
-
-
Stasi, M.A.1
Borsini, F.2
Varani, K.3
Vincenzi, F.4
Di Cesare, M.A.5
Minetti, P.6
Ghirardi, O.7
Carminati, P.8
-
106
-
-
38449097509
-
Adenosine receptor antagonists for cognitive dysfunction: A review of animal studies
-
Takahashi RN, Pamplona FA, Prediger RD (2008) Adenosine receptor antagonists for cognitive dysfunction: A review of animal studies. Front Biosci 13:2614-2632
-
(2008)
Front Biosci
, vol.13
, pp. 2614-2632
-
-
Takahashi, R.N.1
Pamplona, F.A.2
Prediger, R.D.3
-
107
-
-
34249034952
-
Characterization of the antiparkinsonian effects of the new adenosine A 2A receptor antagonist ST1535: Acute and subchronic studies in rats
-
Tronci E, Simola N, Borsini F, Schintu N, Frau L, Carminati P, Morelli M (2007) Characterization of the antiparkinsonian effects of the new adenosine A 2A receptor antagonist ST1535: Acute and subchronic studies in rats. Eur J Pharmacol 566:94-102
-
(2007)
Eur J Pharmacol
, vol.566
, pp. 94-102
-
-
Tronci, E.1
Simola, N.2
Borsini, F.3
Schintu, N.4
Frau, L.5
Carminati, P.6
Morelli, M.7
-
108
-
-
78649750167
-
A role for adenosine A(1) receptor blockade in the ability of caffeine to promote MDMA "Ecstasy"-induced striatal dopamine release
-
Vanattou-Saïfoudine N, Gossen A, Harkin A, Neuropsychopharmacology Research Group (2011) A role for adenosine A(1) receptor blockade in the ability of caffeine to promote MDMA "Ecstasy"-induced striatal dopamine release. Eur J Pharmacol 650:220-228
-
(2011)
Eur J Pharmacol
, vol.650
, pp. 220-228
-
-
Vanattou-Saïfoudine, N.1
Gossen, A.2
Harkin, A.3
Research Group, N.4
-
109
-
-
33745257553
-
Improved spatial recognition memory in mice lacking adenosine A 2A receptors
-
Wang JH, Ma YY, van den Buuse M (2006) Improved spatial recognition memory in mice lacking adenosine A 2A receptors. Exp Neurol 199:438-445
-
(2006)
Exp Neurol
, vol.199
, pp. 438-445
-
-
Wang, J.H.1
Ma, Y.Y.2
Van Den Buuse, M.3
-
110
-
-
84871343716
-
Study on uric acid and the related factors associated with cognition in the patients with Parkinson's disease
-
Wang XJ, Luo WF, Wang LJ, Mao CJ, Wang L, Liu CF (2009) Study on uric acid and the related factors associated with cognition in the patients with Parkinson's disease. Zhonghua Yi Xue Za Zhi 89:1633-1635
-
(2009)
Zhonghua Yi Xue Za Zhi
, vol.89
, pp. 1633-1635
-
-
Wang, X.J.1
Luo, W.F.2
Wang, L.J.3
Mao, C.J.4
Wang, L.5
Liu, C.F.6
-
111
-
-
0034970280
-
SCH 58261, an A (2A) adenosine receptor antagonist, counteracts parkinsonian-like muscle rigidity in rats
-
Wardas J, Konieczny J, Lorenc-Koci E (2001) SCH 58261, an A (2A) adenosine receptor antagonist, counteracts parkinsonian-like muscle rigidity in rats. Synapse 41:160-171
-
(2001)
Synapse
, vol.41
, pp. 160-171
-
-
Wardas, J.1
Konieczny, J.2
Lorenc-Koci, E.3
-
112
-
-
79959381969
-
Selective inactivation of adenosine A( 2A ) receptors in striatal neurons enhances working memory and reversal learning
-
Wei CJ, Singer P, Coelho J, Boison D, Feldon J, Yee BK, Chen JF (2011) Selective inactivation of adenosine A( 2A ) receptors in striatal neurons enhances working memory and reversal learning. Learn Mem 18:459-474
-
(2011)
Learn Mem
, vol.18
, pp. 459-474
-
-
Wei, C.J.1
Singer, P.2
Coelho, J.3
Boison, D.4
Feldon, J.5
Yee, B.K.6
Chen, J.F.7
-
113
-
-
41849085227
-
Adenosine A 2A receptor antagonists exert motor and neuroprotective effects by distinct cellular mechanisms
-
Yu L, Shen HY, Coelho JE, Araújo IM, Huang QY, Day YJ, Rebola N, Canas PM, Rapp EK, Ferrara J et al (2008) Adenosine A 2A receptor antagonists exert motor and neuroprotective effects by distinct cellular mechanisms. Ann Neurol 63:338-346
-
(2008)
Ann Neurol
, vol.63
, pp. 338-346
-
-
Yu, L.1
Shen, H.Y.2
Coelho, J.E.3
Araújo, I.M.4
Huang, Q.Y.5
Day, Y.J.6
Rebola, N.7
Canas, P.M.8
Rapp, E.K.9
Ferrara, J.10
|