The effect of the adenosine A2A antagonist KW-6002 on motor and motivational processes in the rat

Psychopharmacology

Volumn 184, Issue 1, 2006, Pages 46-55

  O'Neill, Martin ^a   Brown, Verity J ^a  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

Author keywords

Anticipatory; Foreperiod; Motivation; Motor readiness; Response inhibition

Indexed keywords

ADENOSINE A2A RECEPTOR ANTAGONIST; DOPAMINE; ISTRADEFYLLINE;

ANTICIPATION; ARTICLE; ASSOCIATION; CONTROLLED STUDY; DOPAMINERGIC ACTIVITY; DOPAMINERGIC NERVE CELL; DRUG EFFECT; DRUG EFFICACY; DRUG RECEPTOR BINDING; MALE; MOTIVATION; MOTOR PERFORMANCE; NONHUMAN; PRIORITY JOURNAL; RAT; REACTION TIME; REWARD; TASK PERFORMANCE; VISUAL STIMULATION;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MOTIVATION; MOTOR ACTIVITY; PURINES; RATS; REACTION TIME; RECEPTOR, ADENOSINE A2A;

EID: 29344464083     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-005-0240-z     Document Type: Article

References (37)

1. Alexander GE, Crutcher MD (1990) Functional architecture of basal ganglia circuits: neural substrates of parallel processing. Trends Neurosci 13:266-271
2. Alexander SP, Reddington M (1989) The cellular localization of adenosine receptors in rat neostriatum. Neuroscience 28:645-651
3. Aoyama S, Kase H, Borrelli E (2000) Rescue of locomotor impairment in dopamine D2 receptor-deficient mice by an adenosine A2A receptor antagonist. J Neurosci 20:5848-5852
4. Aoyama S, Koga K, Mori A, Miyaji H, Sekine S, Kase H, Uchimura T, Kobayashi H, Kuwana Y (2002) Distribution of adenosine A(2A) receptor antagonist KW-6002 and its effect on gene expression in the rat brain. Brain Res 953:119-125
5. Bara-Jimenez W, Sherzai A, Dimitrova T, Favit A, Bibbiani F, Gillespie M, Morris MJ, Mouradian MM, Chase TN (2003) Adenosine A(2A) receptor antagonist treatment of Parkinson's disease. Neurology 61:293-296
6. Baunez C, Nieoullon A, Amalric M (1995) Dopamine and complex sensorimotor integration: further studies in a conditioned motor task in the rat. Neuroscience 65:375-384
7. Bizot JC (1997) Effects of psychoactive drugs on temporal discrimination in rats. Behav Pharmacol 8:293-308
8. Bowman EM, Brown VJ (1998) Effects of excitotoxic lesions of the rat ventral striatum on the perception of reward cost. Exp Brain Res 123:439-448
9. Bowman EM, Aigner TG, Richmond BJ (1996) Neural signals in the monkey ventral striatum related to motivation for juice and cocaine rewards. J Neurophysiol 75:1061-1073
10. Brown VJ, Brasted PJ, Bowman EM (1996) The effect of systemic D-amphetamine on motor versus motivational processes in the rat. Psychopharmacology (Berl) 128:171-180
11. Brown VJ, Robbins TW (1991) Simple and choice reaction time performance following unilateral striatal dopamine depletion in the rat. Impaired motor readiness but preserved response preparation. Brain 114(Pt 1B):513-525
12. Buhusi CV, Meck WH (2002) Differential effects of methamphetamine and haloperidol on the control of an internal clock. Behav Neurosci 116:291-297
13. Chiang TJ, Al-Ruwaitea AS, Mobini S, Ho MY, Bradshaw CM, Szabadi E (2000) The effect of D-amphetamine on performance on two operant timing schedules. Psychopharmacology (Berl) 150:170-184
14. Coccurello R, Breysse N, Amalric M (2004) Simultaneous blockade of adenosine A2A and metabotropic glutamate mGlu5 receptors increase their efficacy in reversing Parkinsonian deficits in rats. Neuropsychopharmacology 29:1451-1461
15. Fenu S, Pinna A, Ongini E, Morelli M (1997) Adenosine A2A receptor antagonism potentiates L-DOPA-induced turning behaviour and c-fos expression in 6-hydroxydopamine-lesioned rats. Eur J Pharmacol 321:143-147
16. Ferre S, Fredholm BB, Morelli M, Popoli P, Fuxe K (1997) Adenosine-dopamine receptor-receptor interactions as an integrative mechanism in the basal ganglia. Trends Neurosci 20:482-487
17. Ferre S, O'Connor WT, Fuxe K, Ungerstedt U (1993) The striopallidal neuron: a main locus for adenosine-dopamine interactions in the brain. J Neurosci 13:5402-5406
18. Grondin R, Bedard PJ, Hadj Tahar A, Gregoire L, Mori A, Kase H (1999) Antiparkinsonian effect of a new selective adenosine A2A receptor antagonist in MPTP-treated monkeys. Neurology 52:1673-1677
19. Haracz JL, Tschanz JT, Wang Z, Griffith KE, Rebec GV (1998) Amphetamine effects on striatal neurons: implications for models of dopamine function. Neurosci Biobehav Rev 22:613-622
20. Hauber W, Munkle M (1995) Stimulation of adenosine A2a receptors in the rat striatum induces catalepsy that is reversed by antagonists of N-methyl-D-aspartate receptors. Neurosci Lett 196:205-208
21. Hauber W, Neuscheler P, Nagel J, Muller CE (2001) Catalepsy induced by a blockade of dopamine D1 or D2 receptors was reversed by a concomitant blockade of adenosine A(2A) receptors in the caudate-putamen of rats. Eur J Neurosci 14:1287-293
22. Hauser RA, Hubble JP, Truong DD (2003) Randomized trial of the adenosine A(2A) receptor antagonist istradefylline in advanced PD. Neurology 61:297-303
23. Kanda T, Jackson MJ, Smith LA, Pearce RK, Nakamura J, Kase H, Kuwana Y, Jenner P (2000) Combined use of the adenosine A (2A) antagonist KW-6002 with L-DOPA or with selective D1 or D2 dopamine agonists increases antiparkinsonian activity but not dyskinesia in MPTP-treated monkeys. Exp Neurol 162:321-327
24. Koga K, Kurokawa M, Ochi M, Nakamura J, Kuwana Y (2000) Adenosine A(2A) receptor antagonists KF17837 and KW-6002 potentiate rotation induced by dopaminergic drugs in hemi-Parkinsonian rats. Eur J Pharmacol 408:249-255
25. Maricq AV, Church RM (1983) The differential effects of haloperidol and methamphetamine on time estimation in the rat. Psychopharmacology (Berl) 79:10-15
26. Matell MS, Meck WH, Nicolelis MA (2003) Interval timing and the encoding of signal duration by ensembles of cortical and striatal neurons. Behav Neurosci 117:760-773
27. Meck WH (1983) Selective adjustment of the speed of internal clock and memory processes. J Exp Psychol Anim Behav Process 9:171-201
28. Meck WH (1986) Affinity for the dopamine D2 receptor predicts neuroleptic potency in decreasing the speed of an internal clock. Pharmacol Biochem Behav 25:1185-1189
29. Meck WH (1996) Neuropharmacology of timing and time perception. Brain Res Cogn Brain Res 3:227-242
30. Mink JW (1996) The basal ganglia: focused selection and inhibition of competing motor programs. Prog Neurobiol 50:381-425
31. Pinna A, di Chiara G, Wardas J, Morelli M (1996) Blockade of A2a adenosine receptors positively modulates turning behaviour and c-Fos expression induced by D1 agonists in dopamine-denervated rats. Eur J Neurosci 8:1176-1181
32. Risterucci C, Terramorsi D, Nieoullon A, Amalric M (2003) Excitotoxic lesions of the prelimbic-infralimbic areas of the rodent prefrontal cortex disrupt motor preparatory processes. Eur J Neurosci 17:1498-508
33. Robbins TW, Everitt BJ (1996) Neurobehavioural mechanisms of reward and motivation. Curr Opin Neurobiol 6:228-236
34. Santi A, Coppa R, Ross L (2001) Effects of the dopamine D2 agonist, quinpirole, on time and number processing in rats. Pharmacol Biochem Behav 68:147-155
35. Shiozaki S, Ichikawa S, Nakamura J, Kitamura S, Yamada K, Kuwana Y (1999) Actions of adenosine A2A receptor antagonist KW-6002 on drug-induced catalepsy and hypokinesia caused by reserpine or MPTP. Psychopharmacology (Berl) 147:90-95
36. Svenningsson P, Le Moine C, Fisone G, Fredholm BB (1999) Distribution, biochemistry and function of striatal adenosine A2A receptors. Prog Neurobiol 59:355-396
37. Wolfensohn S, Lloyd M (1998) Handbook of laboratory animal management and welfare, 2nd edn. Blackwell, Oxford, UK