Profiling formulated monoclonal antibodies by 1H NMR spectroscopy

Analytical Chemistry

Volumn 85, Issue 20, 2013, Pages 9623-9629

  Poppe, Leszek ^a   Jordan, John B ^a   Lawson, Ken ^b   Jerums, Matthew ^b   Apostol, Izydor ^b   Schnier, Paul D ^a  

^a Departments of Molecular Structure   (United States)

^b AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FORMULATION BUFFERS; H NMR SPECTROSCOPY; HIGHER-ORDER STRUCTURE; MONOCLONAL ANTIBODIES (MAB); NUCLEAR MAGNETIC RESONANCE(NMR); PROTON RELAXATION; PULSED FIELD GRADIENTS; STRUCTURAL CHARACTERIZATION;

DIFFUSION; EXPERIMENTS; ISOTOPES; MONOCLONAL ANTIBODIES; PROTEINS; SIGNAL PROCESSING;

NUCLEAR MAGNETIC RESONANCE;

MONOCLONAL ANTIBODY;

ANIMAL; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CHO CELL LINE; CRICETULUS; HAMSTER; HUMAN; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN CONFORMATION;

ANIMALS; ANTIBODIES, MONOCLONAL; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PROTEIN CONFORMATION;

EID: 84886937973     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/ac401867f     Document Type: Article

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