DHHC17 palmitoylates clipR-59 and modulates clipR-59 association with the plasma membrane

Molecular and Cellular Biology

Volumn 33, Issue 21, 2013, Pages 4255-4265

  Ren, Wenying ^a   Sun, Yingmin ^a,b   Du, Keyong ^a  

^a TUFTS MEDICAL CENTER   (United States)

^b CHINA AGRICULTURAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; ASPARTIC ACID HISTIDINE HISTIDINE CYSTEINE; GLUCOSE TRANSPORTER 4; INSULIN; MEMBRANE PROTEIN; MEMBRANE PROTEIN CLIPR59; PALMITOYLTRANSFERASE DHHC17; PROTEIN KINASE B; TRANSFERASE; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; MEMBRANE BIOLOGY; NONHUMAN; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN INTERACTION; WESTERN BLOTTING;

ACYLTRANSFERASES; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL MEMBRANE; CERCOPITHECUS AETHIOPS; COS CELLS; GLUCOSE TRANSPORTER TYPE 4; HEK293 CELLS; HUMANS; INSULIN; LIPOYLATION; MICROTUBULE-ASSOCIATED PROTEINS; NERVE TISSUE PROTEINS; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 84886914670     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00527-13     Document Type: Article

References (30)

1. Perez F, Pernet-Gallay K, Nizak C, Goodson HV, Kreis TE, Goud B. 2002. CLIPR-59, a new trans-Golgi/TGN cytoplasmic linker protein belonging to the CLIP-170 family. J. Cell Biol. 156:631-642.
2. Ding J, Du K. 2009. ClipR-59 interacts with Akt and regulates Akt cellular compartmentalization. Mol. Cell. Biol. 29:1459-1471.
3. Sakamoto K, Holman GD. 2008. Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic. Am. J. Physiol. Endocrinol. Metab. 295:E29-E37.
4. Ren W, Cheema S, Du K. 2012. The association of ClipR-59 protein with AS160 modulates AS160 protein phosphorylation and adipocyte Glut4 protein membrane translocation. J. Biol. Chem. 287:26890-26900.
5. Bogan JS. 2012. Regulation of glucose transporter translocation in health and diabetes. Annu. Rev. Biochem. 81:507-532.
6. Huang S, Czech MP. 2007. The GLUT4 glucose transporter. Cell Metab. 5:237-252.
7. Minokoshi Y, Kahn CR, Kahn BB. 2003. Tissue-specific ablation of the GLUT4 glucose transporter or the insulin receptor challenges assumptions about insulin action and glucose homeostasis. J. Biol. Chem. 278: 33609-33612.
8. Graham TE, Kahn BB. 2007. Tissue-specific alterations of glucose transport and molecular mechanisms of intertissue communication in obesity and type 2 diabetes. Horm. Metab. Res. 39:717-721.
9. Kotani K, Peroni OD, Minokoshi Y, Boss O, Kahn BB. 2004. GLUT4 glucose transporter deficiency increases hepatic lipid production and peripheral lipid utilization. J. Clin. Invest. 114:1666-1675.
10. Lallemand-Breitenbach V, Quesnoit M, Braun V, El Marjou A, Pous C, Goud B, Perez F. 2004. CLIPR-59 is a lipid raft-associated protein containing a cytoskeleton-associated protein glycine-rich domain (CAP-Gly) that perturbs microtubule dynamics. J. Biol. Chem. 279:41168-41178.
11. Mitchell DA, Vasudevan A, Linder ME, Deschenes RJ. 2006. Protein palmitoylation by a family of DHHC protein S-acyltransferases. J. Lipid Res. 47:1118-1127.
12. Greaves J, Chamberlain LH. 2011. DHHC palmitoyl transferases: substrate interactions and (patho)physiology. Trends Biochem. Sci. 36:245-253.
13. Korycka J, Lach A, Heger E, Boguslawska DM, Wolny M, Toporkiewicz M, AugoffK, Korzeniewski J, Sikorski AF. 2012. Human DHHC proteins: a spotlight on the hidden player of palmitoylation. Eur. J. Cell Biol. 91:107-117.
14. Fukata M, Fukata Y, Adesnik H, Nicoll RA, Bredt DS. 2004. Identification of PSD-95 palmitoylating enzymes. Neuron 44:987-996.
15. Huang K, Yanai A, Kang R, Arstikaitis P, Singaraja RR, Metzler M, Mullard A, Haigh B, Gauthier-Campbell C, Gutekunst CA, Hayden MR, El-Husseini A. 2004. Huntingtin-interacting protein HIP14 is a palmitoyl transferase involved in palmitoylation and trafficking of multiple neuronal proteins. Neuron 44:977-986.
16. Huang K, Sanders S, Singaraja R, Orban P, Cijsouw T, Arstikaitis P, Yanai A, Hayden MR, El-Husseini A. 2009. Neuronal palmitoyl acyl transferases exhibit distinct substrate specificity. FASEB J. 23:2605-2615.
17. Du K, Herzig S, Kulkarni RN, Montminy M. 2003. TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver. Science 300: 1574-1577.
18. Fernández-Hernando C, Fukata M, Bernatchez PN, Fukata Y, Lin MI, Bredt DS, Sessa WC. 2006. Identification of Golgi-localized acyl transferases that palmitoylate and regulate endothelial nitric oxide synthase. J. Cell Biol. 174:369-377.
19. Forrester MT, Hess DT, Thompson JW, Hultman R, Moseley MA, Stamler JS, Casey PJ. 2011. Site-specific analysis of protein S-acylation by resin-assisted capture. J. Lipid Res. 52:393-398.
20. Ren W, Jhala US, Du D. 2013. Proteomic analysis of protein palmitoylation in adipocytes. Adipocyte 2:17-28.
21. Roth AF, Feng Y, Chen L, Davis NG. 2002. The yeast DHHC cysteinerich domain protein Akr1p is a palmitoyl transferase. J. Cell Biol. 159: 23-28.
22. Ohno Y, Kashio A, Ogata R, Ishitomi A, Yamazaki Y, Kihara A. 2012. Analysis of substrate specificity of human DHHC protein acyltransferases using a yeast expression system. Mol. Biol. Cell 23:4543-4551.
23. Dawson K, Aviles-Hernandez A, Cushman SW, Malide D. 2001. Insulin-regulated trafficking of dual-labeled glucose transporter 4 in primary rat adipose cells. Biochem. Biophys. Res. Commun. 287:445-454.
24. Ducker CE, Stettler EM, French KJ, Upson JJ, Smith CD. 2004. Huntingtin interacting protein 14 is an oncogenic human protein: palmitoyl acyltransferase. Oncogene 23:9230-9237.
25. Yanai A, Huang K, Kang R, Singaraja RR, Arstikaitis P, Gan L, Orban PC, Mullard A, Cowan CM, Raymond LA, Drisdel RC, Green WN, Ravikumar B, Rubinsztein DC, El-Husseini A, Hayden MR. 2006. Palmitoylation of huntingtin by HIP14 is essential for its trafficking and function. Nat. Neurosci. 9:824-831.
26. Ohno Y, Kihara A, Sano T, Igarashi Y. 2006. Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins. Biochim. Biophys. Acta 1761:474-483.
27. Rocks O, Gerauer M, Vartak N, Koch S, Huang ZP, Pechlivanis M, Kuhlmann J, Brunsveld L, Chandra A, Ellinger B, Waldmann H, Bastiaens PI. 2010. The palmitoylation machinery is a spatially organizing system for peripheral membrane proteins. Cell 141:458-471.
28. Berchtold LA, Storling ZM, Ortis F, Lage K, Bang-Berthelsen C, Bergholdt R, Hald J, Brorsson CA, Eizirik DL, Pociot F, Brunak S, Storling J. 2011. Huntingtin-interacting protein 14 is a type 1 diabetes candidate protein regulating insulin secretion and beta-cell apoptosis. Proc. Natl. Acad. Sci. U. S. A. 108:E681-E688.
29. Fujikura D, Ito M, Chiba S, Harada T, Perez F, Reed JC, Uede T, Miyazaki T. 2012. CLIPR-59 regulates TNF-alpha-induced apoptosis by controlling ubiquitination of RIP1. Cell Death Dis. 3:e264.
30. Couesnon A, Offner N, Bernard V, Chaverot N, Backer S, Dimitrov A, Perez F, Molgo J, Bloch-Gallego E. 2013. CLIPR-59: a protein essential for neuromuscular junction stability during mouse late embryonic development. Development 140:1583-1593.