Tissue-specific alterations of glucose transport and molecular mechanisms of intertissue communication in obesity and type 2 diabetes

Hormone and Metabolic Research

Volumn 39, Issue 10, 2007, Pages 717-721

  Graham, T E ^a   Kahn, B B ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

Adipose tissue; GLUT4; Insulin resistance; Retinol binding protein 4 (RBP4)

Indexed keywords

FENRETINIDE; GLUCOSE TRANSPORTER 4; INSULIN; RECOMBINANT PROTEIN; RECOMBINANT RETINOL BINDING PROTEIN; RETINOL BINDING PROTEIN; ROSIGLITAZONE; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; CELL MEMBRANE; CELL MIGRATION; CONFERENCE PAPER; DRUG BINDING; DRUG MECHANISM; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORT; HUMAN; INSULIN RESISTANCE; INSULIN SENSITIVITY; KNOCKOUT MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKELETAL MUSCLE; TARGET ORGAN; TISSUE SPECIFICITY; WILD TYPE;

ANIMALS; BIOLOGICAL TRANSPORT; CELL COMMUNICATION; DIABETES MELLITUS, TYPE 2; GLUCOSE; GLUCOSE TRANSPORTER TYPE 4; HUMANS; INSULIN RESISTANCE; MODELS, BIOLOGICAL; OBESITY; ORGAN SPECIFICITY; RETINOL-BINDING PROTEINS, PLASMA;

MUS;

EID: 36048934083     PISSN: 00185043     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-985879     Document Type: Conference Paper

References (25)

1. Abel ED, Shepherd PR, Kahn BB. Glucose transporters and pathophysiological states. In: LeRoith DR, Olefsky JM, Taylor SI (eds.) Diabetes Mellitus: A Fundamental and Clinical Text 3rd ed. Philadelphia, PA: JP Lippincott Co. 2004; 917-938
2. Shepherd PR, Kahn BB. Glucose transporters and insulin action - implications for insulin resistance and diabetes mellitus. N Engl J Med 1999; 341: 248-257
3. Abel ED, Peroni O, Kim JK et al. Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver. Nature 2001; 409 (6821): 729-733
4. Shepherd PR, Gnudi L, Tozzo E, Yang H, Leach F, Kahn BB. Adipose cell hyperplasia and enhanced glucose disposal in transgenic mice overexpressing GLUT4 selectively in adipose tissue. J Biol Chem 1993; 268: 22243-22246
5. Gnudi L, Tozzo E, Shepherd PR, Bliss JL, Kahn BB. High level overexpression of glucose transporter-4 driven by an adipose-specific promoter is maintained in transgenic mice on a high fat diet, but does not prevent impaired glucose tolerance. Endocrinology 1995; 136: 995-1002
6. Tozzo E, Gnudi L, Kahn BB. Amelioration of insulin resistance in streptozotocin diabetic mice by transgenic overexpression of GLUT4 driven by an adipose-specific promoter. Endocrinology 1997; 138: 1604-1611
7. Zisman A, Peroni OD, Abel ED et al. Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance. Nat Med 2000; 6: 924-928
8. Kotani K, Peroni OD, Minokoshi Y, Boss O, Kahn BB. GLUT4 glucose transporter deficiency increases hepatic lipid production and peripheral lipid utilization. J Clin Invest 2004; 114: 1666-1675
9. Yang Q, Graham TE, Mody N et al. Serum retinol binding protein contributes to insulin resistance in obesity and type 2 diabetes. Nature 2005; 436 (7049): 356-362
10. Blaner WS. Retinol-binding protein: the serum transport protein for vitamin A. Endocr Rev 1989; 10: 308-316
11. Chambon P. A decade of molecular biology of retinoic acid receptors. Faseb J 1996; 10: 940-954
12. Monaco HL. The transthyretin-retinol-binding protein complex. Biochim Biophys Acta 2000; 1482: 65-72
13. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature 1994; 372 (6505): 425-432
14. Basualdo CG, Wein EE, Basu TK. Vitamin A (retinol) status of first nation adults with non-insulin-dependent diabetes mellitus. J Am Coll Nutr 1997; 16 (1): 39-45
15. Abahusain MA, Wright J, Dickerson JW, Vol EB de. Retinol, alpha-tocopherol and carotenoids in diabetes. Eur J Clin Nutr 1999; 53: 630-635
16. Duggirala R, Blangero J, Almasy L et al. Linkage of type 2 diabetes mellitus and of age at onset to a genetic location on chromosome 10q in Mexican Americans. Am J Hum Genet 1999; 64: 1127-1140
17. Meigs JB, Panhuysen CI, Myers RH, Wilson PW, Cupples LA. A genome-wide scan for loci linked to plasma levels of glucose and HbA(1c) in a community-based sample of Caucasian pedigrees: The Framingham Offspring Study. Diabetes 2002; 51: 833-840
18. Graham TE, Yang Q, Bluher M, Hammarstedt A, Ciaraldi TP, Henry RR, Wason CJ, Oberbach A, Janssen P-A, Smith U, Kahn BB. Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects. N Eng J Med 2006; 354: 2552-2563
19. Carvalho E, Jansson PA, Nagaev I, Wenthzel AM, Smith U. Insulin resistance with low cellular IRS-1 expression is also associated with low GLUT4 expression and impaired insulin-stimulated glucose transport. Faseb J 2001; 15: 1101-1103
20. Quadro L, Blaner WS, Hamberger L et al. Muscle expression of human retinol-binding protein (RBP). Suppression of the visual defect of RBP knockout mice. J Biol Chem 2002; 277: 30191-30197
21. Quadro L, Blaner WS, Salchow DJ et al. Impaired retinal function and vitamin A availability in mice lacking retinol-binding protein. Embo J 1999; 18: 4633-4644
22. Berni R, Formelli F. In vitro interaction of fenretinide with plasma retinol-binding protein and its functional consequences. FEBS Lett 1992; 308: 43-45
23. Schaffer EM, Ritter SJ, Smith JE. N-(4-hydroxyphenyl) retinamide (fenretinide) induces retinol-binding protein secretion from liver and accumulation in the kidneys in rats. J Nutr 1993; 123: 1497-1503
24. Matarese V, Lodish HF. Specific uptake of retinol-binding protein by variant F9 cell lines. J Biol Chem 1993; 268: 18859-18865
25. Sivaprasadarao A, Findlay JB. Structure-function studies on human retinol-binding protein using site-directed mutagenesis. Biochem J 1994; 300 (Pt 2): 437-442