The association of ClipR-59 protein with AS160 modulates AS160 protein phosphorylation and adipocyte Glut4 protein membrane translocation

Journal of Biological Chemistry

Volumn 287, Issue 32, 2012, Pages 26890-26900

  Ren, Wenying ^a   Cheema, Sarwat ^a   Du, Keyong ^a  

^a TUFTS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3T3-L1 ADIPOCYTES; ADIPOCYTES; ANKYRIN; GLUCOSE TRANSPORT; INSULIN SIGNALING; MEMBRANE TRANSLOCATION; MEMBRANE-ASSOCIATED PROTEINS; PROTEIN MEMBRANE; PROTEIN PHOSPHORYLATION; REGULATORY EFFECTS; SCAFFOLD PROTEIN; SUB-CELLULAR; VESICLE TRAFFICKING;

GLUCOSE; INSULIN; MEMBRANES; MOLECULAR WEIGHT; PHOSPHORYLATION;

PROTEINS;

ANKYRIN; CELL MEMBRANE PROTEIN; CLIP 170 RELATED PROTEIN 59 PROTEIN; GLUCOSE; GLUCOSE TRANSPORTER 4; INSULIN; MUTANT PROTEIN; PROTEIN AS160; PROTEIN KINASE B; RAB PROTEIN; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG;

ADIPOCYTE; ARTICLE; CELL COMPARTMENTALIZATION; CELL MEMBRANE TRANSPORT; CONTROLLED STUDY; ENZYME SUBSTRATE; GLUCOSE TRANSPORT; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

3T3 CELLS; ADIPOCYTES; ANIMALS; CELL MEMBRANE; GLUCOSE TRANSPORTER TYPE 4; GTPASE-ACTIVATING PROTEINS; HUMANS; MICE; MICROTUBULE-ASSOCIATED PROTEINS; PHOSPHORYLATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84864573006     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.357699     Document Type: Article

References (29)

1. Whiteman, E. L., Cho, H., and Birnbaum, M. J. (2002) Role of Akt/protein kinase B in metabolism. Trends Endocrinol. Metab. 13, 444-451 (Pubitemid 36733939)
2. Bryant, N. J., Govers, R., and James, D. E. (2002) Regulated transport of the glucose transporter GLUT4. Nat. Rev. Mol. Cell Biol. 3, 267-277 (Pubitemid 34619262)
3. Watson, R. T., and Pessin, J. E. (2006) Bridging the GAP between insulin signaling and GLUT4 translocation. Trends Biochem. Sci. 31, 215-222
4. Sano, H., Eguez, L., Teruel, M. N., Fukuda, M., Chuang, T. D., Chavez, J. A., Lienhard, G. E., and McGraw, T. E. (2007) Rab10, a target of the AS160 Rab GAP, is required for insulin-stimulated translocation of GLUT4 to the adipocyte plasma membrane. Cell Metab. 5, 293-303 (Pubitemid 46477855)
5. Larance, M., Ramm, G., Stöckli, J., van Dam, E. M., Winata, S., Wasinger, V., Simpson, F., Graham, M., Junutula, J. R., Guilhaus, M., and James, D. E. (2005) Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking. J. Biol. Chem. 280, 37803-37813 (Pubitemid 41642391)
6. Welsh, G. I., Leney, S. E., Lloyd-Lewis, B., Wherlock, M., Lindsay, A. J., McCaffrey, M. W., and Tavaré, J. M. (2007) Rip11 is a Rab11- and AS160-RabGAP-binding protein required for insulin-stimulated glucose uptake in adipocytes. J. Cell Sci. 120, 4197-4208
7. Ishikura, S., Bilan, P. J., and Klip, A. (2007) Rab8A and -14 are targets of the insulin-regulated Rab-GAP AS160 regulating GLUT4 traffic in muscle cells. Biochem. Biophys. Res. Commun. 353, 1074-1079 (Pubitemid 46080408)
8. Sano, H., Kane, S., Sano, E., Mîinea, C. P., Asara, J. M., Lane, W. S., Garner, C. W., and Lienhard, G. E. (2003) Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation. J. Biol. Chem. 278, 14599-14602 (Pubitemid 36799780)
9. Eguez, L., Lee, A., Chavez, J. A., Miinea, C. P., Kane, S., Lienhard, G. E., and McGraw, T. E. (2005) Full intracellular retention of GLUT4 requires AS160 Rab GTPase-activating protein. Cell Metab. 2, 263-272
10. Bai, L., Wang, Y., Fan, J., Chen, Y., Ji, W., Qu, A., Xu, P., James, D. E., and Xu, T. (2007) Dissecting multiple steps of GLUT4 trafficking and identifying the sites of insulin action. Cell Metab. 5, 47-57 (Pubitemid 44939397)
11. Kane, S., Sano, H., Liu, S. C., Asara, J. M., Lane, W. S., Garner, C. C., and Lienhard, G. E. (2002) A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain. J. Biol. Chem. 277, 22115-22118 (Pubitemid 34967174)
12. Perez, F., Pernet-Gallay, K., Nizak, C., Goodson, H. V., Kreis, T. E., and Goud, B. (2002) CLIPR-59, a new trans-Golgi/TGN cytoplasmic linker protein belonging to the CLIP-170 family. J. Cell Biol. 156, 631-642 (Pubitemid 34839879)
13. Pierre, P., Scheel, J., Rickard, J. E., and Kreis, T. E. (1992) CLIP-170 links endocytic vesicles to microtubules. Cell 70, 887-900
14. Lallemand-Breitenbach, V., Quesnoit, M., Braun, V., El Marjou, A., Poüs, C., Goud, B., and Perez, F. (2004) CLIPR-59 is a lipid raft-associated protein containing a cytoskeleton-associated protein glycine-rich domain (CAP-Gly) that perturbs microtubule dynamics. J. Biol. Chem. 279, 41168-41178 (Pubitemid 39287719)
15. Ding, J., and Du, K. (2009) ClipR-59 interacts with Akt and regulates Akt cellular compartmentalization. Mol. Cell. Biol. 29, 1459-1471
16. Jiang, K., Coppola, D., Crespo, N. C., Nicosia, S. V., Hamilton, A. D., Sebti, S. M., and Cheng, J. Q. (2000) The phosphoinositide 3-OH kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced apoptosis. Mol. Cell. Biol. 20, 139-148 (Pubitemid 30002555)
17. Shulman, G. I. (2000) Cellular mechanisms of insulin resistance. J. Clin. Invest. 106, 171-176
18. Quon, M. J., Guerre-Millo, M., Zarnowski, M. J., Butte, A. J., Em, M., Cushman, S. W., and Taylor, S. I. (1994) Tyrosine kinase-deficient mutant human insulin receptors (Met-1153 → Ile) overexpressed in transfected rat adipose cells fail to mediate translocation of epitope-tagged GLUT4. Proc. Natl. Acad. Sci. U.S.A. 91, 5587-5591
19. Du, K., Herzig, S., Kulkarni, R. N., and Montminy, M. (2003) TRB3. A tribbles homolog that inhibits Akt/PKB activation by insulin in liver. Science 300, 1574-1577 (Pubitemid 36682889)
20. Mills, I. G., Jones, A. T., and Clague, M. J. (1999) Regulation of endosome fusion. Mol. Membr. Biol. 16, 73-79 (Pubitemid 29179340)
21. Mîinea, C. P., Sano, H., Kane, S., Sano, E., Fukuda, M., Peränen, J., Lane, W. S., and Lienhard, G. E. (2005) AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domain. Biochem. J. 391, 87-93 (Pubitemid 41445479)
22. Dawson, K., Aviles-Hernandez, A., Cushman, S. W., and Malide, D. (2001) Insulin-regulated trafficking of dual-labeled glucose transporter 4 in primary rat adipose cells. Biochem. Biophys. Res. Commun. 287, 445- 454
23. Hill, M. M., Clark, S. F., Tucker, D. F., Birnbaum, M. J., James, D. E., and Macaulay, S. L. (1999) A role for protein kinase Bβ/Akt2 in insulin-stimulated GLUT4 translocation in adipocytes. Mol. Cell. Biol. 19, 7771-7781 (Pubitemid 29493441)
24. Jedrychowski, M. P., Gartner, C. A., Gygi, S. P., Zhou, L., Herz, J., Kandror, K. V., and Pilch, P. F. (2010) Proteomic analysis of GLUT4 storage vesicles reveals LRP1 to be an important vesicle component and target of insulin signaling. J. Biol. Chem. 285, 104-114
25. Stöckli, J., Davey, J. R., Hohnen-Behrens, C., Xu, A., James, D. E., and Ramm, G. (2008) Regulation of glucose transporter 4 translocation by the Rab guanosine triphosphatase-activating protein AS160/TBC1D4. Role of phosphorylation and membrane association. Mol. Endocrinol. 22, 2703-2715
26. Ng, Y., Ramm, G., Burchfield, J. G., Coster, A. C., Stöckli, J., and James, D. E. (2010) Cluster analysis of insulin action in adipocytes reveals a key role for Akt at the plasma membrane. J. Biol. Chem. 285, 2245-2257
27. Kuijl, C., Savage, N. D., Marsman, M., Tuin, A. W., Janssen, L., Egan, D. A., Ketema, M., van den Nieuwendijk, R., van den Eeden, S. J., Geluk, A., Poot, A., van der Marel, G., Beijersbergen, R. L., Overkleeft, H., Ottenhoff, T. H., and Neefjes, J. (2007) Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1. Nature 450, 725-730 (Pubitemid 350207691)
28. Lin, H. V., Ren, H., Samuel, V. T., Lee, H. Y., Lu, T. Y., Shulman, G. I., and Accili, D. (2011) Diabetes in mice with selective impairment of insulin action in Glut4-expressing tissues. Diabetes 60, 700-709
29. Nandi, A., Kitamura, Y., Kahn, C. R., and Accili, D. (2004) Mouse models of insulin resistance. Physiol. Rev. 84, 623-647 (Pubitemid 38365494)